glycine has been researched along with Hyperactivity, Motor in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " They were challenged on the eighth day with one dosage and sacrificed 3 h later." | 1.32 | Activation of metabotropic glutamate receptor 5 is associated with effect of amphetamine on brain neurons. ( Li, LT; Lin, WW; Yin, HS; Yu, MF, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, L | 2 |
| Parlar, S | 2 |
| Kvist, K | 1 |
| Whiteley, P | 2 |
| Shattock, P | 2 |
| Longo, F | 1 |
| Russo, I | 1 |
| Shimshek, DR | 1 |
| Greggio, E | 1 |
| Morari, M | 1 |
| Haracopos, D | 1 |
| Knivsberg, AM | 1 |
| Reichelt, KL | 1 |
| Jacobsen, J | 1 |
| Seim, A | 1 |
| Schondel, M | 1 |
| Ballard, TM | 1 |
| Pauly-Evers, M | 1 |
| Higgins, GA | 1 |
| Ouagazzal, AM | 1 |
| Mutel, V | 1 |
| Borroni, E | 1 |
| Kemp, JA | 1 |
| Bluethmann, H | 1 |
| Kew, JN | 1 |
| Yu, MF | 1 |
| Lin, WW | 1 |
| Li, LT | 1 |
| Yin, HS | 1 |
| Shin, KW | 1 |
| Hong, JT | 1 |
| Yoo, HS | 1 |
| Song, S | 1 |
| Oh, KW | 1 |
| Miranda-Contreras, L | 1 |
| Dávila-Ovalles, R | 1 |
| Benítez-Díaz, P | 1 |
| Peña-Contreras, Z | 1 |
| Palacios-Prü, E | 1 |
| Costa, MJ | 1 |
| Monteiro, DA | 1 |
| Oliveira-Neto, AL | 1 |
| Rantin, FT | 1 |
| Kalinin, AL | 1 |
| Kato, K | 1 |
| Shishido, T | 1 |
| Ono, M | 1 |
| Shishido, K | 1 |
| Kobayashi, M | 1 |
| Niwa, S | 1 |
| Darracq, L | 1 |
| Drouin, C | 1 |
| Blanc, G | 1 |
| Glowinski, J | 1 |
| Tassin, JP | 1 |
| Ma, J | 1 |
| Leung, LS | 1 |
| Toth, E | 1 |
| Lajtha, A | 1 |
| Stern, P | 1 |
| Catović, S | 1 |
| Stern, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A1 Beta Casein Free Milk (a2 Milk) for Autism and Attention-deficit Hyperactivity Disorder[NCT02911194] | 40 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| The ScanBrit Randomised Controlled Study of Gluten- and Casein-free Dietary Intervention for Children With Autism Spectrum Disorders[NCT00614198] | Phase 2 | 72 participants (Actual) | Interventional | 2006-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
ADOS (Autism Diagnostic Observation Schedule): module 1 cutoff scores (communication+social): autism=12, autism spectrum (AS)=7; module 2 cutoffs: autism=12, AS=8; module 3 cutoffs: autism=10; AS=7. GARS (Gilliam Autism Rating Scale): <80 low probability of autism, 81-90 below average, 91-110 average, >110 above average probability of autism. VABS (Vineland Adaptive Behaviour Scale): <69 (low ability), 70-84 (moderate/low), 85-115 (adequate), 116-130 (moderate/high), >130 (high). ADHD-IV: 0=no problems indicated. >11 attention & >11 hyperactivity = ADHD diagnosis. (NCT00614198)
Timeframe: Baseline - 8 months - 12 months - 24 months
| Intervention | Units on a scale (Mean) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADOS - Communication (8 months) | ADOS - Communication (24 months) | ADOS - Social (8 months) | ADOS - Social (24 months) | ADOS - Repetitive behaviours (8 months) | ADOS - Reptitive behaviours (24 months) | GARS - Social (8 months) | GARS - Social (12 months) | GARS - Social (24 months) | GARS - Communication (8 months) | GARS - Communication (12 months) | GARS - Communication (24 months) | GARS - Stereotyped behaviours (8 months) | GARS - Stereotyped behaviours (12 months) | GARS - Stereotyped behaviours (24 months) | VABS - Communication (8 months) | VABS - Communication (12 months) | VABS - Communication (24 months) | VABS - Social (8 months) | VABS - Social (12 months) | VABS - Social (24 months) | VABS - Daily Living (8 months) | VABS - Daily Living (12 months) | VABS - Daily Living (24 months) | ADHD-IV - Inattention (8 months) | ADHD-IV - Inattention (12 months) | ADHD-IV - Inattention (24 months) | ADHD-IV - Hyperactivity (8 months) | ADHD-IV - Hyperactivity (12 months) | ADHD-IV Hyperactivity (24 months) | |
| Gluten- and Casein-free Dietary Intervention | -0.16715 | -0.16176 | 0.016807 | -0.5042 | -0.14706 | -0.14216 | -1.07692 | -1.57692 | -1.88235 | -1.23077 | -1.47826 | -2 | -0.96154 | -1.46154 | -0.88235 | 0.23077 | 0.92308 | 1.27778 | 1.53846 | -4.15385 | 0.72222 | 3.03846 | 3.46154 | -0.16667 | -2.15385 | -2.19231 | -2.29412 | -2.03846 | -1.69231 | -2.58824 |
| No Gluten- and Casein-free Dietary Intervention | 0.08235 | 0.18529 | 0.02521 | 0.02521 | 0.03431 | -0.0049 | -0.06897 | -0.42308 | -1.11765 | -0.51724 | -1.46154 | -1.29412 | -0.7931 | -1.3333 | -1.70588 | 1.25 | 1.85714 | -2.05882 | 0.92857 | -3.25 | -3.29412 | -1.64286 | -2.85714 | -4.64706 | 0.31034 | -0.03704 | -3.35294 | -0.17241 | -0.92593 | -4.17647 |
2 trials available for glycine and Hyperactivity, Motor
| Article | Year |
|---|---|
Data mining the ScanBrit study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders: behavioural and psychometric measures of dietary response.
Topics: Attention; Caseins; Child; Child Development Disorders, Pervasive; Child, Preschool; Data Mining; Di | 2014 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
11 other studies available for glycine and Hyperactivity, Motor
| Article | Year |
|---|---|
Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Analysis of Variance; Animals; Brain; Dose-Res | 2014 |
Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding Sites; Binding, Competitive; Biogenic Amine | 2002 |
Activation of metabotropic glutamate receptor 5 is associated with effect of amphetamine on brain neurons.
Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Brain; Cells, Cultured; Centr | 2003 |
Inhibitory effects of glycine on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity in mice.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Glycine; Hyperkinesis; Male; Mice; Mice, | 2003 |
Effects of prenatal paraquat and mancozeb exposure on amino acid synaptic transmission in developing mouse cerebellar cortex.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Disease Models, Animal; Down-Regulation; Female; Fungicid | 2005 |
Oxidative stress biomarkers and heart function in bullfrog tadpoles exposed to Roundup Original.
Topics: Animals; Catalase; Glycine; Glyphosate; Herbicides; Hyperkinesis; Larva; Liver; Myocardial Contracti | 2008 |
Glycine reduces novelty- and methamphetamine-induced locomotor activity in neonatal ventral hippocampal damaged rats.
Topics: Animals; Disease Models, Animal; Glycine; Hippocampus; Hyperkinesis; Ibotenic Acid; Methamphetamine; | 2001 |
Stimulation of metabotropic but not ionotropic glutamatergic receptors in the nucleus accumbens is required for the D-amphetamine-induced release of functional dopamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Benz | 2001 |
Metabotropic glutamate receptors in the hippocampus and nucleus accumbens are involved in generating seizure-induced hippocampal gamma waves and behavioral hyperactivity.
Topics: Animals; Behavior, Animal; Benzoates; Electroencephalography; Electrophysiology; Excitatory Amino Ac | 2002 |
Antagonism of phencyclidine-induced hyperactivity by glycine in mice.
Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Glycine; Hyperkinesis; Locomotion; Male; | 1986 |
Mechanism of action of substance P.
Topics: Animals; Brain Chemistry; Diethylamines; Glycine; Humans; Hyperkinesis; Male; Mice; Nitriles; Spinal | 1974 |