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glycine and Hemoglobinopathies

glycine has been researched along with Hemoglobinopathies in 14 studies

Hemoglobinopathies: A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.

Research Excerpts

ExcerptRelevanceReference
"The biosynthesis of two types of human fetal hemoglobin (Hb F), namely Hb F with G gamma chains having glycine in position 136 and Hb F with A gamma chains having alanine in position 136, was studied in blood samples and in cultures of erythroid precursors from blood of patients with different hemoglobinopathies."3.66The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu ( Efremov, GD; Gravely, ME; Harris, HF; Howard, JS; Huisman, TH; Reese, AL; Wilson, JB, 1979)
" In Greek double heterozygotes for beta-thalassemia and the hereditary persistence of fetal hemoglobin, fetal hemoglobin is increased above the level of hemoglobin F in simple heterozygotes and gamma-chains with glycine in position 136 become apparent."3.65Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia. ( Apell, G; Bouver, N; Huisman, TH; Schroeder, WA; Shelton, JB; Shelton, JR; Stamatoyannopoulos, G, 1970)
"He showed mild polycythemia, and his whole blood dissociation curve for oxygen was clearly left-shifted, with a decreased p50."1.28Functional properties of Hb-J Calabria, beta 64 (E8) Gly-Asp. ( Bertello, PD; Bonetti, G; Izzo, P; Rabino Massa, E; Ricco, G, 1991)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marinucci, M1
Giampaolo, A1
Maffi, D1
Mavilio, F1
Cianetti, L1
Mulè, F1
Tentori, L1
Iuchi, I1
Shimasaki, S1
Hidaka, K1
Ueda, S1
Harano, T1
Shibata, S1
Mizushima, J1
Ohnishi, Y1
Clegg, JB2
Metaxatou-Mavromati, A1
Kattamis, C1
Sofroniadou, K1
Wood, WG2
Weatherall, DJ2
Huisman, TH7
Efremov, GD2
Reese, AL1
Howard, JS1
Gravely, ME1
Harris, HF1
Wilson, JB2
Rabino Massa, E1
Bonetti, G1
Izzo, P1
Bertello, PD1
Ricco, G1
Gordon-Smith, EC1
Dacie, JV1
Blecher, TE1
French, EA1
Wiltshirre, BG1
Lehmann, H1
Schroeder, WA6
Sukumaran, PK2
Sadikario, A1
Stojmirovic, E1
Shelton, JR5
Shelton, JB5
Apell, G5
Brodie, AR1
Bouver, NG1
Miller, A1
Mann, JR1
MacNeish, AS1
Bannister, D1
McCurdy, PR1
Freehafer, JT1
Bouver, N2
Blackwell, RQ1
Boon, WH1
Liu, CS1
Weng, MI1
Dozy, AM1
Boyd, EM1
Stamatoyannopoulos, G1

Other Studies

14 other studies available for glycine and Hemoglobinopathies

ArticleYear
The biosynthesis of hemoglobin G San Josè (beta 7(A4) Glu replaced by Gly).
    Acta haematologica, 1981, Volume: 66, Issue:2

    Topics: Adult; Genetic Carrier Screening; Glutamine; Glycine; Hemoglobinopathies; Hemoglobins, Abnormal; Hum

1981
Hemoglobin J Bangkok (beta 56[D7]Gly leads to Asp): a hemoglobin variant discovered by the hemoglobinopathy survey in Takamatsu district.
    Hemoglobin, 1981, Volume: 5, Issue:2

    Topics: Amino Acids; Aspartic Acid; Electrophoresis, Cellulose Acetate; Genetic Variation; Glycine; Hemoglob

1981
Occurrence of G gamma Hb F in Greek HPFH: analysis of heterozygotes and compound heterozygotes with beta thalassaemia.
    British journal of haematology, 1979, Volume: 43, Issue:4

    Topics: Adult; Alanine; Erythrocyte Indices; Female; Fetal Hemoglobin; Globins; Glycine; Greece; Hemoglobin

1979
The synthesis of fetal hemoglobin types in red blood cells and in BFU-E derived colonies from peripheral blood of patients with sickle cell anemia, beta+ - and delta beta-thalassemia, various forms of hereditary persistence of fetal hemoglobin, normal adu
    Hemoglobin, 1979, Volume: 3, Issue:4

    Topics: Adult; Alanine; Anemia, Sickle Cell; Cells, Cultured; Chromatography, High Pressure Liquid; Clone Ce

1979
Functional properties of Hb-J Calabria, beta 64 (E8) Gly-Asp.
    Bollettino della Societa italiana di biologia sperimentale, 1991, Volume: 67, Issue:1

    Topics: Adult; Female; Glycine; Hemoglobin J; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Hydrogen-Io

1991
Haemoglobin Nottingham, beta FG 5 (98) valgly: a new unstable haemoglobin producing severe haemolysis.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:6

    Topics: Child, Preschool; Female; Glycine; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Infant; Valine

1973
A second type of hereditary persistence of foetal haemoglobin in India.
    British journal of haematology, 1973, Volume: 25, Issue:1

    Topics: Adult; Alanine; Amino Acid Sequence; Child; Child, Preschool; Female; Fetal Hemoglobin; Globins; Gly

1973
Chemical heterogeneity of foetal haemoglobin in the Lepore haemoglobinopathy.
    British journal of haematology, 1974, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Chemical Phenomena; Chemistry; Child; Chromatograph

1974
Chemical heterogeneity of fetal hemoglobin in subjects with sickle cell anemia, homozygous Hb-C disease, SC disease, and various combinations of hemoglobin variants.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Alanine; Anemia, Sickle Cell; Child; Child, Preschool; Chromatograph

1972
Delta-beta-thalassaemia in a Chinese family.
    British journal of haematology, 1972, Volume: 23, Issue:4

    Topics: Adult; Alanine; Asian People; Black People; Carbon Isotopes; Child; Child, Preschool; Chromatography

1972
A homozygote for the Hb G type of foetal haemoglobin in India: a study of two Indian and four Negro families.
    British journal of haematology, 1972, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Black People; Child; Child, Preschool; District of Col

1972
Hemoglobin J Singapore: alpha 78 Asn--Asp; alpha 79 Ala--Gly.
    Biochimica et biophysica acta, 1972, Oct-31, Volume: 278, Issue:3

    Topics: Adult; Alanine; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Che

1972
Evidence for multiple structural genes for the gamma-chain of human fetal hemoglobin in hereditary persistence of fetal hemoglobin.
    Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

    Topics: Adolescent; Adult; Aged; Alanine; Child; Child, Preschool; Erythrocyte Count; Female; Fetal Hemoglob

1969
Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:5

    Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Chromatography, Paper; Fetal Hemoglobin; Glycine; Hem

1970