glycine has been researched along with Granulocytic Leukemia, Chronic in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute lymphoblastic leukemia (ALL) is a disease of lymphoid progenitor cells with an often aggressive course and is commonly caused by the BCR-ABL fusion gene t(9;22) in adults." | 1.72 | Combined inhibition of BCR-ABL1 and the proteasome as a potential novel therapeutic approach in BCR-ABL positive acute lymphoblastic leukemia. ( Appelmann, I; Brümmendorf, TH; Koschmieder, S; Maletzke, S; Masouleh, BK; Salimi, A; Schemionek, M; Schroeder, KM; Vieri, M, 2022) |
| "Acute and chronic myeloid leukemia are initiated and sustained by a small, self-renewing population of leukemic stem cells, which produce progeny of a heterogeneous population of progenitor cells." | 1.40 | Stromal cell derived factor-1 (CXCL12) chemokine gene variant in myeloid leukemias. ( Bahaa, NM; El-Ghany, HM; El-Saadany, ZA; Hussien, SM; Ibrahim, NY, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, C | 1 |
| Zou, W | 1 |
| Nie, D | 1 |
| Li, S | 1 |
| Duan, C | 1 |
| Zhou, M | 1 |
| Lai, P | 1 |
| Yang, S | 1 |
| Ji, S | 1 |
| Li, Y | 1 |
| Mei, M | 1 |
| Bao, S | 1 |
| Jin, Y | 1 |
| Pan, J | 1 |
| Maletzke, S | 1 |
| Salimi, A | 1 |
| Vieri, M | 1 |
| Schroeder, KM | 1 |
| Schemionek, M | 1 |
| Masouleh, BK | 1 |
| Brümmendorf, TH | 1 |
| Koschmieder, S | 1 |
| Appelmann, I | 1 |
| Navada, SC | 1 |
| Garcia-Manero, G | 1 |
| OdchimarReissig, R | 1 |
| Pemmaraju, N | 1 |
| Alvarado, Y | 1 |
| Ohanian, MN | 1 |
| John, RB | 1 |
| Demakos, EP | 1 |
| Zbyszewski, PS | 1 |
| Maniar, M | 1 |
| Woodman, RC | 1 |
| Fruchtman, SM | 1 |
| Silverman, LR | 1 |
| El-Ghany, HM | 1 |
| El-Saadany, ZA | 1 |
| Bahaa, NM | 1 |
| Ibrahim, NY | 1 |
| Hussien, SM | 1 |
| Okabe, S | 1 |
| Tauchi, T | 1 |
| Tanaka, Y | 1 |
| Sakuta, J | 1 |
| Ohyashiki, K | 1 |
| Engür, S | 1 |
| Dikmen, M | 1 |
| Öztürk, Y | 1 |
| FUJII, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I/II, Multi-center, Dose-escalating Study of the Tolerability, Pharmacokinetics, and Clinical Activity of the Combined Administration of Oral Rigosertib With Azacitidine in Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia[NCT01926587] | Phase 1/Phase 2 | 45 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for glycine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Rigosertib in combination with azacitidine in patients with myelodysplastic syndromes or acute myeloid leukemia: Results of a phase 1 study.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Female; Glycine; Humans; Leukemia, Myelogenous, Chronic | 2020 |
6 other studies available for glycine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML.
Topics: Animals; Epigenesis, Genetic; Glycine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, M | 2022 |
Combined inhibition of BCR-ABL1 and the proteasome as a potential novel therapeutic approach in BCR-ABL positive acute lymphoblastic leukemia.
Topics: Adult; Aged; Boron Compounds; Bortezomib; Dasatinib; Drug Resistance, Neoplasm; Fusion Proteins, bcr | 2022 |
Stromal cell derived factor-1 (CXCL12) chemokine gene variant in myeloid leukemias.
Topics: 3' Untranslated Regions; Adolescent; Adult; Aged; Alanine; Case-Control Studies; Chemokine CXCL12; F | 2014 |
Efficacy of the polo-like kinase inhibitor rigosertib, alone or in combination with Abelson tyrosine kinase inhibitors, against break point cluster region-c-Abelson-positive leukemia cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Glycine; Humans; Leukemia, Myelogenous, Chronic, BC | 2015 |
Comparison of antiproliferative and apoptotic effects of a novel proteasome inhibitor MLN2238 with bortezomib on K562 chronic myeloid leukemia cells.
Topics: Apoptosis; Boron Compounds; Bortezomib; Cell Proliferation; Dose-Response Relationship, Drug; Drug S | 2016 |
BIOSYNTHESIS OF HEME AND STERCOBILIN IN CHRONIC MYELOID LEUKEMIA AND IRON DEFICIENCY ANEMIA. STUDY WITH 2-14C-GLYCINE.
Topics: Anemia; Anemia, Hypochromic; Anemia, Iron-Deficiency; Bile Pigments; Glycine; Heme; Humans; Leukemia | 1964 |