glycine has been researched along with Frontotemporal Lobar Degeneration in 5 studies
Frontotemporal Lobar Degeneration: Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "FUS-positive inclusions in FTLD and ALS patients are consistently co-labeled with stress granule (SG) marker proteins." | 1.38 | Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43). ( Bentmann, E; Dormann, D; Haass, C; Neumann, M; Rodde, R; Tahirovic, S, 2012) |
| "We identified 1 patient with FTLD with a novel missense mutation, M254V, that was absent in 638 control individuals." | 1.36 | Genetic contribution of FUS to frontotemporal lobar degeneration. ( Cruts, M; De Deyn, PP; Engelborghs, S; Gijselinck, I; Mattheijssens, M; Peeters, K; Sleegers, K; Van Broeckhoven, C; Van den Broeck, M; van der Zee, J; Van Langenhove, T; Vandenberghe, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gleixner, AM | 1 |
| Verdone, BM | 1 |
| Otte, CG | 1 |
| Anderson, EN | 1 |
| Ramesh, N | 1 |
| Shapiro, OR | 1 |
| Gale, JR | 1 |
| Mauna, JC | 1 |
| Mann, JR | 1 |
| Copley, KE | 1 |
| Daley, EL | 1 |
| Ortega, JA | 1 |
| Cicardi, ME | 1 |
| Kiskinis, E | 1 |
| Kofler, J | 1 |
| Pandey, UB | 1 |
| Trotti, D | 1 |
| Donnelly, CJ | 1 |
| Chattopadhyay, K | 1 |
| Van Langenhove, T | 1 |
| van der Zee, J | 1 |
| Sleegers, K | 1 |
| Engelborghs, S | 1 |
| Vandenberghe, R | 1 |
| Gijselinck, I | 1 |
| Van den Broeck, M | 1 |
| Mattheijssens, M | 1 |
| Peeters, K | 1 |
| De Deyn, PP | 1 |
| Cruts, M | 1 |
| Van Broeckhoven, C | 1 |
| Bentmann, E | 1 |
| Neumann, M | 1 |
| Tahirovic, S | 1 |
| Rodde, R | 1 |
| Dormann, D | 1 |
| Haass, C | 1 |
| Wang, YT | 1 |
| Kuo, PH | 1 |
| Chiang, CH | 1 |
| Liang, JR | 1 |
| Chen, YR | 1 |
| Wang, S | 1 |
| Shen, JC | 1 |
| Yuan, HS | 1 |
5 other studies available for glycine and Frontotemporal Lobar Degeneration
| Article | Year |
|---|---|
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
Topics: Amyotrophic Lateral Sclerosis; C9orf72 Protein; Dipeptides; DNA Repeat Expansion; DNA-Binding Protei | 2022 |
Probing the influence of mutations on FUS condensates, one molecule at a time.
Topics: Amyotrophic Lateral Sclerosis; Frontotemporal Lobar Degeneration; Glycine; Humans; Mutation; RNA-Bin | 2021 |
Genetic contribution of FUS to frontotemporal lobar degeneration.
Topics: Aged; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; DNA Mutational Analysis; DNA-Binding Prote | 2010 |
Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).
Topics: Amyotrophic Lateral Sclerosis; Binding Sites; Cerebral Cortex; DNA-Binding Proteins; Frontotemporal | 2012 |
The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.
Topics: Amino Acid Motifs; Amyloidogenic Proteins; Amyotrophic Lateral Sclerosis; Benzothiazoles; Chromatogr | 2013 |