Page last updated: 2024-10-18

glycine and Fatty Liver, Nonalcoholic

glycine has been researched along with Fatty Liver, Nonalcoholic in 17 studies

Research Excerpts

ExcerptRelevanceReference
" Glycine-β-muricholic acid (Gly-MCA) is an intestine-specific FXR antagonist previously shown to have favorable metabolic effects on obesity and insulin resistance."4.12Glycine-β-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice. ( Amin, SG; Desai, D; Gao, X; Gonzalez, FJ; Jiang, J; Krausz, KW; Liu, Y; Lu, D; Ma, Y; Patterson, AD; Xie, C, 2022)
"Patients with chronic hepatitis C are expected to receive this treatment worldwide."2.52Does herbal medicine reduce the risk of hepatocellular carcinoma? ( Rino, Y; Yamamoto, N; Yukawa, N, 2015)
"NAFLD and liver fibrosis were diagnosed using transient elastography and subjects were divided into three groups: normal, NAFLD, and liver fibrosis."1.56Changed Amino Acids in NAFLD and Liver Fibrosis: A Large Cross-Sectional Study without Influence of Insulin Resistance. ( Endo, T; Fukuda, S; Hasegawa, T; Iino, C; Kimura, M; Mikami, K; Nakaji, S; Sawada, N, 2020)
"Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease in developed countries."1.56Glyphosate Excretion is Associated With Steatohepatitis and Advanced Liver Fibrosis in Patients With Fatty Liver Disease. ( Caussy, C; Loomba, R; Mills, PJ, 2020)
"Glycine is a non-essential amino acid having multiple roles in many reactions."1.38Glycine alleviates liver injury induced by deficiency in methionine and or choline in rats. ( Barakat, HA; Hamza, AH, 2012)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (64.71)24.3611
2020's6 (35.29)2.80

Authors

AuthorsStudies
Jiang, J1
Ma, Y1
Liu, Y2
Lu, D1
Gao, X1
Krausz, KW1
Desai, D1
Amin, SG1
Patterson, AD2
Gonzalez, FJ1
Xie, C1
Chen, D1
Liang, Y1
Liang, J1
Shen, F1
Cheng, Y1
Qu, H1
Wa, Y1
Guo, C1
Gu, R1
Qian, J1
Chen, X1
Zhang, C2
Guan, C1
Yamamoto, S1
Sato, I1
Fujii, M1
Kakimoto, M1
Honma, K1
Akiyama, N1
Sakai, M1
Fukuhama, N1
Kumazaki, S1
Hirohata, S1
Kitamori, K2
Yamori, Y1
Watanabe, S1
Vildhede, A1
Kimoto, E1
Pelis, RM1
Rodrigues, AD1
Varma, MVS1
Hasegawa, T1
Iino, C1
Endo, T1
Mikami, K1
Kimura, M1
Sawada, N1
Nakaji, S1
Fukuda, S1
Allen, J1
Zhang, J1
Quickel, MD1
Kennett, M1
Hankey-Giblin, PA1
Khukhlina, O1
Antoniv, A1
Kanovska, L1
Mandryk, O1
Smandych, V1
Mills, PJ1
Caussy, C1
Loomba, R1
Alves, A1
Bassot, A1
Bulteau, AL1
Pirola, L1
Morio, B1
Suzuki, Y1
Kaneko, R1
Nomura, M1
Naito, H1
Nakajima, T1
Ogawa, T1
Hattori, H1
Seno, H1
Ishii, A1
Rogue, A1
Anthérieu, S1
Vluggens, A1
Umbdenstock, T1
Claude, N1
de la Moureyre-Spire, C1
Weaver, RJ1
Guillouzo, A1
Rino, Y1
Yukawa, N1
Yamamoto, N1
Zang, S1
Wang, L1
Ma, X1
Zhu, G1
Zhuang, Z1
Xun, Y1
Zhao, F1
Yang, W1
Liu, J1
Luo, Y1
Ye, D1
Shi, J1
Zhou, X1
Han, D1
Xu, R1
Wu, H1
Qu, C1
Wang, F1
Wang, X1
Zhao, Y1
Mesnage, R1
Renney, G1
Séralini, GE1
Ward, M1
Antoniou, MN1
Mardinoglu, A1
Bjornson, E1
Klevstig, M1
Söderlund, S1
Ståhlman, M1
Adiels, M1
Hakkarainen, A1
Lundbom, N1
Kilicarslan, M1
Hallström, BM1
Lundbom, J1
Vergès, B1
Barrett, PH1
Watts, GF1
Serlie, MJ1
Nielsen, J1
Uhlén, M1
Smith, U1
Marschall, HU1
Taskinen, MR1
Boren, J1
Barakat, HA1
Hamza, AH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Glycine on Atherosclerosis and Metabolic Syndrome-related Parameters: A Clinical and Ex-vivo Study.[NCT03850314]Phase 2/Phase 350 participants (Anticipated)Interventional2019-03-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for glycine and Fatty Liver, Nonalcoholic

ArticleYear
Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases.
    Nutrients, 2019, Jun-16, Volume: 11, Issue:6

    Topics: Biological Availability; Diabetes Mellitus, Type 2; Diet; Gastrointestinal Microbiome; Glycine; Huma

2019
Does herbal medicine reduce the risk of hepatocellular carcinoma?
    World journal of gastroenterology, 2015, Oct-07, Volume: 21, Issue:37

    Topics: Animals; Anti-Inflammatory Agents; Benzimidazoles; Carcinoma, Hepatocellular; Clinical Trials as Top

2015

Other Studies

15 other studies available for glycine and Fatty Liver, Nonalcoholic

ArticleYear
Glycine-β-muricholic acid antagonizes the intestinal farnesoid X receptor-ceramide axis and ameliorates NASH in mice.
    Hepatology communications, 2022, Volume: 6, Issue:12

    Topics: Animals; Ceramides; Glycine; Intestines; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Receptors

2022
Beneficial effects of Lactobacillus rhamnosus hsryfm 1301 fermented milk on rats with nonalcoholic fatty liver disease.
    Journal of dairy science, 2023, Volume: 106, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Cholesterol; D-Aspartic Aci

2023
Increased Glycine-conjugated and Unconjugated Bile Acid Levels Associated with Aggravation of Nonalcoholic Steatohepatitis and Cardiovascular Disease in SHRSP5/Dmcr Rat.
    Acta medica Okayama, 2023, Volume: 77, Issue:1

    Topics: Animals; Bile Acids and Salts; Cardiovascular Diseases; Glycine; Non-alcoholic Fatty Liver Disease;

2023
Quantitative Proteomics and Mechanistic Modeling of Transporter-Mediated Disposition in Nonalcoholic Fatty Liver Disease.
    Clinical pharmacology and therapeutics, 2020, Volume: 107, Issue:5

    Topics: Aniline Compounds; Chromatography, Liquid; Glucuronides; Glycine; Humans; Imino Acids; Membrane Tran

2020
Changed Amino Acids in NAFLD and Liver Fibrosis: A Large Cross-Sectional Study without Influence of Insulin Resistance.
    Nutrients, 2020, May-17, Volume: 12, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Cross-Sectional Studies; Female; Glutamic Acid; Glycine

2020
Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model.
    Journal of proteome research, 2018, 09-07, Volume: 17, Issue:9

    Topics: Animals; Apolipoproteins E; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Collagen; Cytokines; D

2018
EFFECTIVENESS OF NONALCOHOLIC STEATOHEPATITIS CORRECTION ON THE BAСKGROUND OF OBESITY WITH CONCOMITANT CHRONIC KIDNEY DISEASE.
    Georgian medical news, 2018, Issue:283

    Topics: Administration, Oral; Anti-Inflammatory Agents; Cysteine; Drug Administration Schedule; Drug Combina

2018
Glyphosate Excretion is Associated With Steatohepatitis and Advanced Liver Fibrosis in Patients With Fatty Liver Disease.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2020, Volume: 18, Issue:3

    Topics: Carcinoma, Hepatocellular; Disease Progression; Glycine; Glyphosate; Humans; Liver; Liver Cirrhosis;

2020
Simple and rapid quantitation of 21 bile acids in rat serum and liver by UPLC-MS-MS: effect of high fat diet on glycine conjugates of rat bile acids.
    Nagoya journal of medical science, 2013, Volume: 75, Issue:1-2

    Topics: Animals; Bile Acids and Salts; Biomarkers; Calibration; Cholesterol, Dietary; Chromatography, Liquid

2013
PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells.
    Toxicology and applied pharmacology, 2014, Apr-01, Volume: 276, Issue:1

    Topics: Cell Line; Constitutive Androstane Receptor; Drug Evaluation, Preclinical; Fatty Acids, Nonesterifie

2014
Neutrophils Play a Crucial Role in the Early Stage of Nonalcoholic Steatohepatitis via Neutrophil Elastase in Mice.
    Cell biochemistry and biophysics, 2015, Volume: 73, Issue:2

    Topics: Alanine Transaminase; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apolipoprote

2015
Glycine protects against high sucrose and high fat-induced non-alcoholic steatohepatitis in rats.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cytoprotection; Diet, High-Fat; Dietary Sucrose; Disea

2016
Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide.
    Scientific reports, 2017, 01-09, Volume: 7

    Topics: Animals; Disease Models, Animal; Glycine; Glyphosate; Herbicides; Liver; Metabolomics; Non-alcoholic

2017
Personal model-assisted identification of NAD
    Molecular systems biology, 2017, 03-02, Volume: 13, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Genome; Glutathion

2017
Glycine alleviates liver injury induced by deficiency in methionine and or choline in rats.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:6

    Topics: Animals; Antioxidants; Choline Deficiency; Fatty Liver; Glycine; Lipid Metabolism; Lipid Peroxidatio

2012