glycine has been researched along with Epilepsies, Partial in 12 studies
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amino acid analysis of plasma and urine obtained from 12 patients with epilepsy indicated that the plasma concentrations of taurine and glutamic acid were much higher than might have been expected." | 7.65 | Biochemical observations following administration of taurine to patients with epilepsy. ( Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM, 1975) |
| "Amino acid analysis of plasma and urine obtained from 12 patients with epilepsy indicated that the plasma concentrations of taurine and glutamic acid were much higher than might have been expected." | 3.65 | Biochemical observations following administration of taurine to patients with epilepsy. ( Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM, 1975) |
| "The patient developed a series of partial seizures during an 8 min period." | 1.28 | Seizure related elevations of extracellular amino acids in human focal epilepsy. ( Carlson, H; Hillered, L; Ronne-Engström, E; Ungerstedt, U, 1992) |
| "Glycine content was elevated markedly in some foci, whereas aspartic acid content was normal." | 1.26 | Amino acid abnormalities in epileptogenic foci. ( Hansen, S; Perry, TL, 1981) |
| "In mice showing sound induced seizures, clobazam, 1--4 mg/kg, i." | 1.26 | Anticonvulsant action of a 1,5-benzodiazepine, clobazam, in reflex epilepsy. ( Chapman, AG; Horton, RW; Meldrum, BS, 1978) |
| "Glycine content was markedly elevated in two of 16 epileptogenic foci." | 1.25 | Amino acids in human epileptogenic foci. ( Hansen, S; Kennedy, J; Perry, TL; Thompson, GB; Wada, JA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leschziner, GD | 1 |
| Coffey, AJ | 1 |
| Andrew, T | 1 |
| Gregorio, SP | 1 |
| Dias-Neto, E | 1 |
| Calafato, M | 1 |
| Bentley, DR | 1 |
| Kinton, L | 1 |
| Sander, JW | 1 |
| Johnson, MR | 1 |
| Hammond, EJ | 1 |
| Wilder, BJ | 1 |
| Bruni, J | 1 |
| Perry, TL | 2 |
| Hansen, S | 2 |
| Sherwin, AL | 3 |
| Chapman, AG | 1 |
| Horton, RW | 1 |
| Meldrum, BS | 1 |
| Fariello, RG | 1 |
| Van Gelder, NM | 3 |
| Sacks, C | 1 |
| Anderman, F | 1 |
| Kennedy, J | 1 |
| Wada, JA | 1 |
| Thompson, GB | 1 |
| Carlson, H | 1 |
| Ronne-Engström, E | 1 |
| Ungerstedt, U | 1 |
| Hillered, L | 1 |
| Abdul-Ghani, AS | 1 |
| Rasmussen, T | 1 |
| Courtois, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study in Adolescents With Bipolar Disorder[NCT00391001] | Phase 1 | 4 participants (Actual) | Interventional | 2006-02-28 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for glycine and Epilepsies, Partial
| Article | Year |
|---|---|
Central actions of valproic acid in man and in experimental models of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Action Potentials; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; | 1981 |
Neuroactive amino acids in focally epileptic human brain: a review.
Topics: Aspartic Acid; Brain; Epilepsies, Partial; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic | 1999 |
10 other studies available for glycine and Epilepsies, Partial
| Article | Year |
|---|---|
Q8IYL2 is a candidate gene for the familial epilepsy syndrome of Partial Epilepsy with Pericentral Spikes (PEPS).
Topics: Alanine; Brazil; Computational Biology; DNA Copy Number Variations; Epilepsies, Partial; Family Heal | 2011 |
Amino acid abnormalities in epileptogenic foci.
Topics: Adolescent; Adult; Aged; Amino Acids; Aspartic Acid; Cerebral Cortex; Child; Epilepsies, Partial; Fr | 1981 |
Anticonvulsant action of a 1,5-benzodiazepine, clobazam, in reflex epilepsy.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzodiazepinones; Disease Models, Animal; Drug Eval | 1978 |
Action of inhibitory amino acids on acute epileptic foci: an electrographic study.
Topics: Animals; beta-Alanine; Blood Pressure; Cats; Electroencephalography; Epilepsies, Partial; Female; ga | 1979 |
Biochemical observations following administration of taurine to patients with epilepsy.
Topics: Adolescent; Adult; Alanine; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Child; Child, Preschool | 1975 |
Amino acids in human epileptogenic foci.
Topics: Adolescent; Adult; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Child; Cystathionine; Epile | 1975 |
Seizure related elevations of extracellular amino acids in human focal epilepsy.
Topics: Amino Acids; Asparagine; Aspartic Acid; Cerebral Cortex; Dialysis; Electroencephalography; Epilepsie | 1992 |
Effect of alpha-amino-4-phosphonobutyrate on the release of endogenous glutamate and aspartate from cortical synaptosomes of epileptic rats.
Topics: Aminobutyrates; Animals; Anticonvulsants; Aspartic Acid; Cobalt; Epilepsies, Partial; Female; gamma- | 1985 |
Amino acid content of epileptogenic human brain: focal versus surrounding regions.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Cerebral Cortex; Chil | 1972 |
Close correlation between changing content of specific amino acids in epileptogenic cortex of cats, and severity of epilepsy.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Cerebral Cortex; Cobalt; Electro | 1972 |