Page last updated: 2024-10-18

glycine and Endotoxemia

glycine has been researched along with Endotoxemia in 16 studies

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
"Glycine is well known to protect the intestine against ischemia-reperfusion injury and during mechanical manipulation."7.80Glycine selectively reduces intestinal injury during endotoxemia. ( de Groot, H; Effenberger-Neidnicht, K; Jägers, J; Verhaegh, R, 2014)
"Hydrogen sulfide (H2S) is a naturally occurring gaseous transmitter, which may play important roles in normal physiology and disease."5.33Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia. ( Anuar, FB; Bhatia, M; Collin, M; Moore, PK; Murch, O; Thiemermann, C, 2005)
"Glycine is well known to protect the intestine against ischemia-reperfusion injury and during mechanical manipulation."3.80Glycine selectively reduces intestinal injury during endotoxemia. ( de Groot, H; Effenberger-Neidnicht, K; Jägers, J; Verhaegh, R, 2014)
"Male SD rats were sacrificed to acute endotoxemia and pretreated with H2S donor sodium hydrogen sulfide (NaHS) or H2S inhibitor dl-propargylglycine (PAG)."3.79Endogenous hydrogen sulfide formation mediates the liver damage in endotoxemic rats. ( Chen, C; Chen, L; Gao, H; Gao, L; Sun, Y; Yan, Y; Zhao, R; Zhou, H, 2013)
"Hydrogen sulfide (H2S) is a naturally occurring gaseous transmitter, which may play important roles in normal physiology and disease."1.40Propargylglycine aggravates liver damage in LPS-treated rats: Possible relation of nitrosative stress with the inhibition of H2S formation. ( Bekpinar, S; Gurdol, F; Unlucerci, Y; Uysal, M, 2014)
"Hydrogen sulfide (H2S) is a naturally occurring gaseous transmitter, which may play important roles in normal physiology and disease."1.33Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia. ( Anuar, FB; Bhatia, M; Collin, M; Moore, PK; Murch, O; Thiemermann, C, 2005)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's6 (37.50)29.6817
2010's7 (43.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Fukuta, T2
Okada, H2
Takemura, G2
Suzuki, K2
Takada, C2
Tomita, H2
Suzuki, A1
Oda, K2
Uchida, A2
Matsuo, S2
Fukuda, H1
Yano, H2
Muraki, I1
Zaikokuji, R2
Kuroda, A2
Nishio, A1
Sampei, S2
Miyazaki, N2
Hotta, Y1
Yamada, N1
Watanabe, T2
Morishita, K2
Doi, T1
Yoshida, T2
Ushikoshi, H2
Yoshida, S2
Maekawa, Y2
Ogura, S2
Kawaguchi, T1
Hamburger, T1
Broecker-Preuss, M1
Hartmann, M1
Schade, FU1
de Groot, H2
Petrat, F1
Norris, EJ1
Feilen, N1
Nguyen, NH1
Culberson, CR1
Shin, MC1
Fish, M1
Clemens, MG1
Effenberger-Neidnicht, K1
Jägers, J1
Verhaegh, R1
Bekpinar, S1
Unlucerci, Y1
Uysal, M1
Gurdol, F1
Zhou, X1
Han, D1
Xu, R1
Wu, H1
Qu, C1
Wang, F1
Wang, X1
Zhao, Y1
Yan, Y1
Chen, C1
Zhou, H1
Gao, H1
Chen, L2
Gao, L1
Zhao, R1
Sun, Y1
Bruck, R1
Wardi, J1
Aeed, H1
Avni, Y1
Shirin, H1
Avinoach, I1
Shahmurov, M1
Hershkoviz, R1
Endler, G1
Marsik, C1
Joukhadar, C1
Marculescu, R1
Mayr, F1
Mannhalter, C1
Wagner, OF1
Jilma, B1
Collin, M1
Anuar, FB1
Murch, O1
Bhatia, M1
Moore, PK1
Thiemermann, C1
Loï, C1
Kana, G1
Blanc, MC1
Genthon, C1
Cynober, L2
Eriksson, M2
Larsson, A2
Saldeen, T2
Mattsson, C2
Chambon-Savanovitch, C1
Felgines, C1
Farges, MC1
Raul, F1
Cézard, JP1
Davot, P1
Vasson, MP1
Cynober, LA1
Schlegel, L1
Coudray-Lucas, C1
Barbut, F1
Le Boucher, J1
Jardel, A1
Zarrabian, S1

Other Studies

16 other studies available for glycine and Endotoxemia

ArticleYear
Neutrophil Elastase Inhibition Ameliorates Endotoxin-induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx.
    Shock (Augusta, Ga.), 2020, Volume: 54, Issue:3

    Topics: Animals; Endotoxemia; Endotoxins; Glycine; Glycocalyx; Granulocyte-Macrophage Colony-Stimulating Fac

2020
Neutrophil Elastase Damages the Pulmonary Endothelial Glycocalyx in Lipopolysaccharide-Induced Experimental Endotoxemia.
    The American journal of pathology, 2019, Volume: 189, Issue:8

    Topics: Animals; Endothelium; Endotoxemia; Glycine; Glycocalyx; Leukocyte Elastase; Lipopolysaccharides; Lun

2019
Effects of glycine, pyruvate, resveratrol, and nitrite on tissue injury and cytokine response in endotoxemic rats.
    The Journal of surgical research, 2013, Volume: 183, Issue:1

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Cytokines; Disease Models, Animal; Drug Therapy, Combin

2013
Hydrogen sulfide modulates sinusoidal constriction and contributes to hepatic microcirculatory dysfunction during endotoxemia.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Jun-15, Volume: 304, Issue:12

    Topics: Alkynes; Animals; Endothelins; Endotoxemia; Enzyme Inhibitors; Escherichia coli; Glycine; Hemodynami

2013
Glycine selectively reduces intestinal injury during endotoxemia.
    The Journal of surgical research, 2014, Volume: 192, Issue:2

    Topics: Animals; Disease Models, Animal; Endotoxemia; Enteritis; Gastrointestinal Hemorrhage; Glycine; Glyci

2014
Propargylglycine aggravates liver damage in LPS-treated rats: Possible relation of nitrosative stress with the inhibition of H2S formation.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:5

    Topics: Alkynes; Amidohydrolases; Animals; Arginine; Aspartate Aminotransferases; Chromatography, High Press

2014
Glycine protects against high sucrose and high fat-induced non-alcoholic steatohepatitis in rats.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cytoprotection; Diet, High-Fat; Dietary Sucrose; Disea

2016
Endogenous hydrogen sulfide formation mediates the liver damage in endotoxemic rats.
    Research in veterinary science, 2013, Volume: 94, Issue:3

    Topics: Alanine Transaminase; Alkynes; Animals; Aspartate Aminotransferases; Cystathionine gamma-Lyase; Endo

2013
Glycine modulates cytokine secretion, inhibits hepatic damage and improves survival in a model of endotoxemia in mice.
    Liver international : official journal of the International Association for the Study of the Liver, 2003, Volume: 23, Issue:4

    Topics: Adjuvants, Immunologic; Animals; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Disease Mod

2003
The interleukin-6 G(-174)C promoter polymorphism does not determine plasma interleukin-6 concentrations in experimental endotoxemia in humans.
    Clinical chemistry, 2004, Volume: 50, Issue:1

    Topics: Adult; Endotoxemia; Glycine; Humans; Interleukin-6; Lipopolysaccharides; Male; Plasma; Polymorphism,

2004
Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia.
    British journal of pharmacology, 2005, Volume: 146, Issue:4

    Topics: Alanine Transaminase; Alkynes; Analysis of Variance; Animals; Blood Pressure; Chemotaxis, Leukocyte;

2005
Evaluation of a glycine-rich amino acid solution for parenteral nutrition in endotoxemic rats.
    Critical care medicine, 2005, Volume: 33, Issue:10

    Topics: Amino Acids; Animals; Creatinine; Disease Models, Animal; Endotoxemia; Glycine; Glycine Agents; Lipo

2005
Melagatran, a low molecular weight thrombin inhibitor, counteracts endotoxin-induced haemodynamic and renal dysfunctions in the pig.
    Thrombosis and haemostasis, 1998, Volume: 80, Issue:6

    Topics: Animals; Azetidines; Benzylamines; Blood Coagulation; Creatinine; Diuresis; Drug Evaluation, Preclin

1998
Comparative study of glycine, alanine or casein as inert nitrogen sources in endotoxemic rats.
    The Journal of nutrition, 1999, Volume: 129, Issue:10

    Topics: Alanine; Analysis of Variance; Animals; Body Weight; Caseins; Endotoxemia; Glycine; Intestinal Mucos

1999
Effects of melagatran, an inhibitor of thrombin, on fibrin deposits, haemodynamics, and platelet count in endotoxaemic pigs.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:1

    Topics: Animals; Anticoagulants; Azetidines; Benzylamines; Endotoxemia; Female; Fibrin; Glycine; Hemodynamic

2000
Bacterial dissemination and metabolic changes in rats induced by endotoxemia following intestinal E. coli overgrowth are reduced by ornithine alpha-ketoglutarate administration.
    The Journal of nutrition, 2000, Volume: 130, Issue:12

    Topics: Animals; Bacterial Translocation; Endotoxemia; Enteral Nutrition; Escherichia coli; Escherichia coli

2000