glycine has been researched along with Electrocardiogram QT Prolonged in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ivosidenib is a once daily (q." | 3.01 | Population pharmacokinetic and exposure-response analyses of ivosidenib in patients with IDH1-mutant advanced hematologic malignancies. ( Fan, B; Jiang, X; Kapsalis, S; Kleijn, HJ; Le, K; Liu, G; Liu, H; Poland, B; Wada, R; Yang, H, 2021) |
| "Congenital long QT syndrome is a cardiac disorder characterized by prolongation of QT interval on the surface ECG associated with syncopal attacks and a high risk of sudden death." | 1.35 | The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes. ( Du, R; Li, W; Song, ZF; Tian, L; Wang, QF; Yang, JG, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, X | 1 |
| Wada, R | 1 |
| Poland, B | 1 |
| Kleijn, HJ | 1 |
| Fan, B | 2 |
| Liu, G | 2 |
| Liu, H | 2 |
| Kapsalis, S | 1 |
| Yang, H | 2 |
| Le, K | 1 |
| Caltabiano, S | 1 |
| Collins, J | 1 |
| Serbest, G | 1 |
| Morgan, L | 1 |
| Smith, DA | 1 |
| Ravindranath, R | 1 |
| Cobitz, AR | 1 |
| Dai, D | 1 |
| Nabhan, S | 1 |
| Hickman, D | 1 |
| Zacher, J | 1 |
| Vutikullird, A | 1 |
| Prakash, C | 1 |
| Agresta, S | 1 |
| Bowden, C | 1 |
| Okata, S | 1 |
| Yuasa, S | 1 |
| Yamane, T | 1 |
| Furukawa, T | 1 |
| Fukuda, K | 1 |
| Yamaguchi, Y | 1 |
| Nishide, K | 1 |
| Kato, M | 1 |
| Hata, Y | 1 |
| Mizumaki, K | 1 |
| Kinoshita, K | 1 |
| Nonobe, Y | 1 |
| Tabata, T | 1 |
| Sakamoto, T | 1 |
| Kataoka, N | 1 |
| Nakatani, Y | 1 |
| Ichida, F | 1 |
| Mori, H | 1 |
| Fukurotani, K | 1 |
| Inoue, H | 1 |
| Nishida, N | 1 |
| Li, W | 1 |
| Du, R | 1 |
| Wang, QF | 1 |
| Tian, L | 1 |
| Yang, JG | 1 |
| Song, ZF | 1 |
| Delisle, BP | 1 |
| Anderson, CL | 1 |
| Balijepalli, RC | 1 |
| Anson, BD | 1 |
| Kamp, TJ | 1 |
| January, CT | 1 |
| Lai, LP | 1 |
| Deng, CL | 1 |
| Moss, AJ | 1 |
| Kass, RS | 1 |
| Liang, CS | 1 |
| Akimoto, K | 1 |
| Furutani, M | 1 |
| Imamura, S | 1 |
| Furutani, Y | 1 |
| Kasanuki, H | 1 |
| Takao, A | 1 |
| Momma, K | 1 |
| Matsuoka, R | 1 |
| Benhorin, J | 1 |
| Goldmit, M | 1 |
| MacCluer, JW | 1 |
| Blangero, J | 1 |
| Goffen, R | 1 |
| Leibovitch, A | 1 |
| Rahat, A | 1 |
| Wang, Q | 1 |
| Medina, A | 1 |
| Towbin, J | 1 |
| Kerem, B | 1 |
| Jahr, S | 1 |
| Lewalter, T | 1 |
| Hesch, RD | 1 |
| Lüderitz, B | 1 |
| Englisch, S | 1 |
| Seebohm, G | 1 |
| Scherer, CR | 1 |
| Busch, AE | 1 |
| Lerche, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation[NCT02074839] | Phase 1 | 291 participants (Anticipated) | Interventional | 2014-03-31 | Recruiting | ||
| Long QT Syndrome-Population Genetics and Cardiac Studies[NCT00005176] | 2,125 participants (Actual) | Observational | 1985-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for glycine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Population pharmacokinetic and exposure-response analyses of ivosidenib in patients with IDH1-mutant advanced hematologic malignancies.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under | 2021 |
A Randomized, Placebo- and Positive-Controlled, Single-Dose, Crossover Thorough QT/QTc Study Assessing the Effect of Daprodustat on Cardiac Repolarization in Healthy Subjects.
Topics: Adolescent; Adult; Barbiturates; Cross-Over Studies; Dose-Response Relationship, Drug; Electrocardio | 2017 |
Effect of itraconazole, food, and ethnic origin on the pharmacokinetics of ivosidenib in healthy subjects.
Topics: Administration, Oral; Adult; Antineoplastic Agents; Area Under Curve; Asian People; Cross-Over Studi | 2019 |
Glycine/Serine polymorphism at position 38 influences KCNE1 subunit's modulatory actions on rapid and slow delayed rectifier K+ currents.
Topics: Amino Acid Substitution; Female; Glycine; HEK293 Cells; Humans; Ion Transport; Long QT Syndrome; Mal | 2014 |
Polymorphism of the gene encoding a human minimal potassium ion channel (minK).
Topics: Alleles; Animals; Base Sequence; Chromosomes, Human, Pair 11; Codon; DNA Primers; Genetic Carrier Sc | 1994 |
7 other studies available for glycine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
The generation of induced pluripotent stem cells from a patient with KCNH2 G603D, without LQT2 disease associated symptom.
Topics: Adenine; Aspartic Acid; Cell Culture Techniques; Child; ERG1 Potassium Channel; Ether-A-Go-Go Potass | 2013 |
The G314S KCNQ1 mutation exerts a dominant-negative effect on expression of KCNQ1 channels in oocytes.
Topics: Action Potentials; Amino Acid Sequence; Animals; Electrophysiological Phenomena; Genes, Dominant; Gl | 2009 |
Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Cation Transport Proteins; Cell Line; Cell Membr | 2003 |
Novel missense mutation (G601S) of HERG in a Japanese long QT syndrome family.
Topics: Amino Acid Substitution; Cation Transport Proteins; Codon; DNA; DNA Mutational Analysis; DNA-Binding | 1998 |
Identification of a new SCN5A mutation, D1840G, associated with the long QT syndrome. Mutations in brief no. 153. Online.
Topics: Amino Acid Substitution; Aspartame; Glycine; Humans; Long QT Syndrome; Mutation; NAV1.5 Voltage-Gate | 1998 |
New missense mutation (G626V) in the predicted selectivity filter of the HERG channel associated with familial long QT syndrome.
Topics: Cation Transport Proteins; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Cha | 2000 |
Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome.
Topics: Amino Acid Sequence; Animals; Arrhythmias, Cardiac; Electrophysiology; Glycine; Humans; KCNQ Potassi | 2001 |