Page last updated: 2024-10-18

glycine and Edema

glycine has been researched along with Edema in 24 studies

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"SNPs in renin (rs2368564) and endothelin-1 (rs5370) were associated with reduced risk of edema (P=0."9.13Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists. ( Achanzar, W; Cheng, P; Cosma, G; Delmonte, T; Dracopoli, NC; Geese, WJ; Hariharan, N; Hui, L; Krishnan, B; Ordway, N; Ranade, K; Rubin, C; Tomlinson, L, 2008)
"Muraglitazar, a dual PPARalpha/gamma agonist, caused a robust increase in body weight in db/db mice."7.74Increase in weight induced by muraglitazar, a dual PPARalpha/gamma agonist, in db/db mice: adipogenesis/or oedema? ( Bansal, VS; Bora, RS; Gupta, A; Khanna, V; Khattar, SK; Mittra, S; Priyadarsiny, P; Roy, S; Saini, KS; Sangle, G; Sattigeri, J; Sharma, L; Sharma, S; Tandon, R, 2007)
"SNPs in renin (rs2368564) and endothelin-1 (rs5370) were associated with reduced risk of edema (P=0."5.13Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists. ( Achanzar, W; Cheng, P; Cosma, G; Delmonte, T; Dracopoli, NC; Geese, WJ; Hariharan, N; Hui, L; Krishnan, B; Ordway, N; Ranade, K; Rubin, C; Tomlinson, L, 2008)
" In particular, the glycine derivative proved to be extremely active in suppressing hyperalgesia and edema."3.80Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors. ( Alfonso, S; Anzini, M; Battilocchio, C; Biava, M; Calderone, V; Colovic, M; Consalvi, S; Di Capua, A; Di Cesare Mannelli, L; Dovizio, M; Ghelardini, C; Giordani, A; Martelli, A; Patrignani, P; Persiani, S; Poce, G; Rossi, A; Sautebin, L; Testai, L, 2014)
"Muraglitazar, a dual PPARalpha/gamma agonist, caused a robust increase in body weight in db/db mice."3.74Increase in weight induced by muraglitazar, a dual PPARalpha/gamma agonist, in db/db mice: adipogenesis/or oedema? ( Bansal, VS; Bora, RS; Gupta, A; Khanna, V; Khattar, SK; Mittra, S; Priyadarsiny, P; Roy, S; Saini, KS; Sangle, G; Sattigeri, J; Sharma, L; Sharma, S; Tandon, R, 2007)
"We aimed to measure glycine production in children with edematous and nonedematous severe childhood undernutrition."3.73Glycine production in severe childhood undernutrition. ( Badaloo, A; Forrester, T; Jahoor, F; Reid, M, 2006)
"ST 679 dose-dependently inhibited carrageenan-, concanavalin A-, and nystatin-induced oedema."3.68Profile of activity of a new anti-inflammatory agent, ST 679 (MED 15). ( Arrigoni-Martelli, E, 1990)
"Muraglitazar is a dual (alpha/gamma) PPAR activator."2.74Efficacy and safety of muraglitazar: a double-blind, 24-week, dose-ranging study in patients with type 2 diabetes. ( Fiedorek, FT; Rubin, CJ; Viraswami-Appanna, K, 2009)
"Glyphosate is an organophosphorus compound and the active ingredient in commonly used herbicides, whereas polyoxyethyleneamine (POEA) is a nonionic surfactant often coupled with glyphosate in these herbicides to increase their efficacy."1.62Glyphosate and Polyoxyethyleneamine Ingestion Leading to Renal, Hepatic, and Pulmonary Failure. ( Bigner, JA; Burney, HE; Fiester, SE; Fulcher, JW; Schammel, CMG; Teuber, JM; Ward, ME; Wheeler, JF; Wheeler, SK, 2021)
"Rat acute inflammation was induced by subcutaneous injection of carrageenan in hind paws."1.42The investigation of anti-inflammatory activity of volatile oil of Angelica sinensis by plasma metabolomics approach. ( Hua, Y; Ji, P; Li, J; Li, P; Wei, Y; Yao, W; Zhang, L; Zhao, H; Zhong, L, 2015)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's7 (29.17)18.2507
2000's10 (41.67)29.6817
2010's4 (16.67)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Bigner, JA1
Fiester, SE1
Fulcher, JW1
Schammel, CMG1
Ward, ME1
Burney, HE1
Wheeler, JF1
Wheeler, SK1
Teuber, JM1
Biava, M1
Battilocchio, C1
Poce, G1
Alfonso, S1
Consalvi, S1
Di Capua, A1
Calderone, V1
Martelli, A1
Testai, L1
Sautebin, L1
Rossi, A1
Ghelardini, C1
Di Cesare Mannelli, L1
Giordani, A1
Persiani, S1
Colovic, M1
Dovizio, M1
Patrignani, P1
Anzini, M1
Yao, W1
Zhang, L1
Hua, Y1
Ji, P1
Li, P1
Li, J1
Zhong, L1
Zhao, H1
Wei, Y1
Mikusic, NLR1
Roson, MI1
Penna, SLD1
Choi, MR1
Gorzalczany, S1
Zotta, E1
Toblli, JE1
Fernandez, BE1
Geese, WJ1
Achanzar, W1
Rubin, C1
Hariharan, N1
Cheng, P1
Tomlinson, L1
Ordway, N1
Dracopoli, NC1
Delmonte, T1
Hui, L1
Krishnan, B1
Cosma, G1
Ranade, K1
Rubin, CJ1
Viraswami-Appanna, K1
Fiedorek, FT1
Rasheed, A1
Ashok Kumar, CK1
Bhatia, M1
Sidhapuriwala, J1
Moochhala, SM1
Moore, PK1
Serena, J1
Blanco, M1
Castellanos, M1
Silva, Y1
Vivancos, J1
Moro, MA1
Leira, R1
Lizasoain, I1
Castillo, J1
Dávalos, A1
Sharma, HS1
Rincón, AC1
Molina-Martinez, IT1
de Las Heras, B1
Alonso, M1
Baílez, C1
Rodríguez-Cabello, JC1
Herrero-Vanrell, R1
Jahoor, F1
Badaloo, A1
Reid, M1
Forrester, T1
Mittra, S1
Sangle, G1
Tandon, R1
Sharma, S1
Roy, S1
Khanna, V1
Gupta, A1
Sattigeri, J1
Sharma, L1
Priyadarsiny, P1
Khattar, SK1
Bora, RS1
Saini, KS1
Bansal, VS1
Burstein, SH1
Adams, JK1
Bradshaw, HB1
Fraioli, C1
Rossetti, RG1
Salmonsen, RA1
Shaw, JW1
Walker, JM1
Zipkin, RE1
Zurier, RB1
Zhang, JX1
Li, SH1
Li, XH1
Qiu, LY1
Li, XD1
Li, XJ1
Jin, Y1
Zhu, KJ1
Hahn, RG2
Grangeiro, TB1
Schriefer, A1
Calvete, JJ1
Raida, M1
Urbanke, C1
Barral-Netto, M1
Cavada, BS1
Schulz, E3
Kobow, M3
Sprung, WD3
Arrigoni-Martelli, E1
Salem, SI1
Hegazi, SM1
Morcos, SR1
Matveev, MP1
Chudnovskaia, MV1
Sukhanberdina, FKh1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Dose Ranging, Dose Comparison-Controlled Trial to Determine the Safety and Efficacy of BMS-298585 in Subjects With Type 2 Diabetes[NCT00240383]Phase 2/Phase 31,260 participants Interventional2002-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for glycine and Edema

ArticleYear
Irrigating fluids in endoscopic surgery.
    British journal of urology, 1997, Volume: 79, Issue:5

    Topics: Absorption; Body Temperature; Brain; Edema; Endoscopy; Glycine; Hemodynamics; Humans; Hypotension; R

1997

Trials

3 trials available for glycine and Edema

ArticleYear
Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists.
    Pharmacogenetics and genomics, 2008, Volume: 18, Issue:10

    Topics: Animals; Diabetes Mellitus, Type 2; Edema; Endothelin-1; Female; Gene Expression Regulation; Glycine

2008
Efficacy and safety of muraglitazar: a double-blind, 24-week, dose-ranging study in patients with type 2 diabetes.
    Diabetes & vascular disease research, 2009, Volume: 6, Issue:3

    Topics: Biomarkers; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; D

2009
The prediction of malignant cerebral infarction by molecular brain barrier disruption markers.
    Stroke, 2005, Volume: 36, Issue:9

    Topics: Aged; Biomarkers; Blood-Brain Barrier; Brain; Case-Control Studies; Edema; Female; Fibronectins; gam

2005

Other Studies

20 other studies available for glycine and Edema

ArticleYear
Glyphosate and Polyoxyethyleneamine Ingestion Leading to Renal, Hepatic, and Pulmonary Failure.
    The American journal of forensic medicine and pathology, 2021, Sep-01, Volume: 42, Issue:3

    Topics: Acute Kidney Injury; Adult; Edema; Glycine; Glyphosate; Hemorrhage; Herbicides; Humans; Liver; Liver

2021
Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors.
    Bioorganic & medicinal chemistry, 2014, Jan-15, Volume: 22, Issue:2

    Topics: Acetic Acid; Amides; Animals; Carrageenan; Cell Line; Constriction, Pathologic; Cyclooxygenase 2; Cy

2014
The investigation of anti-inflammatory activity of volatile oil of Angelica sinensis by plasma metabolomics approach.
    International immunopharmacology, 2015, Volume: 29, Issue:2

    Topics: Angelica sinensis; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Edema; Glycine;

2015
Synthesis and Biological Evaluation of New N-(4-Substituted phenyl)glycine Derivatives as Potential Anti-inflammatory Agents.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2016, Volume: 15, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Diclofenac; Disease Models, Animal; Drug Design; Dru

2016
Tyrosine and glycine derivatives as potential prodrugs: design, synthesis, and pharmacological evaluation of amide derivatives of mefenamic acid.
    Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:6

    Topics: Amides; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Ede

2010
Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat.
    British journal of pharmacology, 2005, Volume: 145, Issue:2

    Topics: Alkynes; Animals; Carrageenan; Cystathionine gamma-Lyase; Edema; Glycine; Hindlimb; Hydrogen Sulfide

2005
Hyperthermia influences excitatory and inhibitory amino acid neurotransmitters in the central nervous system. An experimental study in the rat using behavioural, biochemical, pharmacological, and morphological approaches.
    Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:4

    Topics: Animals; Aspartic Acid; Behavior, Animal; Blood-Brain Barrier; Brain; Capillary Permeability; Cerebr

2006
Biocompatibility of elastin-like polymer poly(VPAVG) microparticles: in vitro and in vivo studies.
    Journal of biomedical materials research. Part A, 2006, Volume: 78, Issue:2

    Topics: Alanine; Amino Acid Sequence; Animals; Biocompatible Materials; Cell Survival; Conjunctivitis; Edema

2006
Glycine production in severe childhood undernutrition.
    The American journal of clinical nutrition, 2006, Volume: 84, Issue:1

    Topics: Amino Acids; Edema; Female; Glycine; Hemoglobins; Humans; Infant; Infant Nutrition Disorders; Infect

2006
Increase in weight induced by muraglitazar, a dual PPARalpha/gamma agonist, in db/db mice: adipogenesis/or oedema?
    British journal of pharmacology, 2007, Volume: 150, Issue:4

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Blood Glucose; Body Weight; Cell Differentiation; E

2007
Potential anti-inflammatory actions of the elmiric (lipoamino) acids.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Alanine; Animals; Anti-Inflammatory Agents; Cell Line; Cell Proliferation; Chromatography, Thin Laye

2007
Physicochemical characterization, in vitro, and in vivo evaluation of indomethacin-loaded nanocarriers self-assembled by amphiphilic polyphosphazene.
    Journal of biomedical materials research. Part A, 2008, Sep-15, Volume: 86, Issue:4

    Topics: Acrylamides; Acrylic Resins; Animals; Arthritis; Carrageenan; Dose-Response Relationship, Drug; Drug

2008
Life-threatening transurethral resection syndrome despite monitoring of fluid absorption with ethanol.
    European journal of anaesthesiology, 1995, Volume: 12, Issue:4

    Topics: Absorption; Aged; Edema; Ethanol; Fluid Therapy; Glycine; Humans; Hypotension; Indicators and Reagen

1995
Molecular cloning and characterization of ConBr, the lectin of Canavalia brasiliensis seeds.
    European journal of biochemistry, 1997, Aug-15, Volume: 248, Issue:1

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; Edema;

1997
[Anti-inflammatory action of structural analogs of dl-2-phenylglycine esters and amides].
    Die Pharmazie, 1992, Volume: 47, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Female; Glycine; Male; Rats

1992
Analgesic and anti-inflammatory activity of DL-2-(alkoxyphenyl)glycine octyl esters.
    Agents and actions, 1991, Volume: 32, Issue:1-2

    Topics: Analgesia; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Female;

1991
[The pharmacologic activity of p-substituted DL-2-phenylglycine octyl esters].
    Die Pharmazie, 1990, Volume: 45, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Caprylates; Carrageenan;

1990
Profile of activity of a new anti-inflammatory agent, ST 679 (MED 15).
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Concanavalin

1990
Experimental protein-energy deficiency in rats. Ratio of serine+glycine to threonine as an index of deficiency.
    The British journal of nutrition, 1973, Volume: 29, Issue:1

    Topics: Amino Acids; Animals; Blood Proteins; Body Weight; Chromatography; Diarrhea; Dietary Proteins; Edema

1973
[Some data on the developmental mechanism of nephrotic edema].
    Voprosy okhrany materinstva i detstva, 1969, Volume: 14, Issue:7

    Topics: Asparagine; Blood Proteins; Child; Child, Preschool; Edema; Female; Glutamine; Glycine; Humans; Male

1969