glycine has been researched along with Disease, Pulmonary in 32 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors evaluated the protective effect of sivelestat sodium on postoperative lung dysfunction in patients with type A acute aortic dissection who underwent aortic arch surgery with cardiopulmonary bypass (CPB) under deep hypothermia with circulatory arrest (DHCA)." | 7.74 | Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study. ( Dardik, A; Kainuma, M; Kondo, Y; Muto, A; Nishibe, T; Ohara, Y; Takeda, K, 2008) |
| "Hydrogen sulfide (H2S) is a naturally occurring gas with potent vasodilator activity." | 5.33 | Role of hydrogen sulfide in acute pancreatitis and associated lung injury. ( Bhatia, M; Fu, D; Lau, HY; Moochhala, SM; Moore, PK; Wong, FL, 2005) |
| "The authors evaluated the protective effect of sivelestat sodium on postoperative lung dysfunction in patients with type A acute aortic dissection who underwent aortic arch surgery with cardiopulmonary bypass (CPB) under deep hypothermia with circulatory arrest (DHCA)." | 3.74 | Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study. ( Dardik, A; Kainuma, M; Kondo, Y; Muto, A; Nishibe, T; Ohara, Y; Takeda, K, 2008) |
| "Sivelestat sodium was administered within 24 h after the onset of respiratory dysfunction in 87." | 1.36 | A survey of the effects of sivelestat sodium administration on patients with postoperative respiratory dysfunction. ( Harada, N; Harimoto, N; Kakeji, Y; Koga, T; Maehara, Y; Miyazaki, M; Morita, M; Nagata, S; Oki, E; Saeki, H, 2010) |
| "Hydrogen sulfide (H2S) is a naturally occurring gas with potent vasodilator activity." | 1.33 | Role of hydrogen sulfide in acute pancreatitis and associated lung injury. ( Bhatia, M; Fu, D; Lau, HY; Moochhala, SM; Moore, PK; Wong, FL, 2005) |
| "Ischemia-reperfusion injury is a significant problem in lung transplantation." | 1.32 | The effects of a specific neutrophil elastase inhibitor (ONO-5046) in pulmonary ischemia-reperfusion injury. ( Ishikawa, N; Kawaguchi, M; Oda, M; Tsunezuka, Y; Watanabe, G, 2003) |
| "Lung hemorrhage was seen in the animals with pancreatitis untreated with ONO-5046 24 hr following the first cerulein injection." | 1.29 | Neutrophil elastase inhibitor (ONO-5046) prevents lung hemorrhage induced by lipopolysaccharide in rat model of cerulein pancreatitis. ( Guo, L; Ikei, S; Ogawa, M; Sugita, H; Yamaguchi, Y, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 11 (34.38) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, LW | 1 |
| Anahtar, MN | 1 |
| Ong, TH | 1 |
| Hern, KE | 1 |
| Kunz, RR | 1 |
| Bhatia, SN | 1 |
| Pandher, U | 1 |
| Kirychuk, S | 1 |
| Schneberger, D | 1 |
| Thompson, B | 1 |
| Aulakh, G | 1 |
| Sethi, RS | 1 |
| Singh, B | 1 |
| Calkins, KL | 1 |
| Sanchez, LA | 1 |
| Tseng, CH | 1 |
| Faull, KF | 1 |
| Yoon, AJ | 1 |
| Ryan, CM | 1 |
| Le, T | 1 |
| Shew, SB | 1 |
| Gaggar, A | 1 |
| Weathington, N | 1 |
| Ando, M | 1 |
| Murai, T | 1 |
| Takahashi, Y | 1 |
| Nishibe, T | 1 |
| Kondo, Y | 1 |
| Muto, A | 1 |
| Dardik, A | 1 |
| Ohara, Y | 1 |
| Kainuma, M | 1 |
| Takeda, K | 1 |
| Morimoto, N | 1 |
| Morimoto, K | 1 |
| Morimoto, Y | 1 |
| Takahashi, H | 1 |
| Asano, M | 1 |
| Matsumori, M | 1 |
| Okada, K | 1 |
| Okita, Y | 1 |
| Yokoyama, T | 1 |
| Tsushima, K | 1 |
| Ushiki, A | 1 |
| Kobayashi, N | 1 |
| Urushihata, K | 1 |
| Koizumi, T | 3 |
| Kubo, K | 3 |
| Saeki, H | 1 |
| Morita, M | 1 |
| Harada, N | 1 |
| Harimoto, N | 1 |
| Nagata, S | 1 |
| Miyazaki, M | 1 |
| Koga, T | 1 |
| Oki, E | 1 |
| Kakeji, Y | 1 |
| Maehara, Y | 1 |
| Iwahashi, M | 1 |
| Nakamori, M | 1 |
| Nakamura, M | 1 |
| Ojima, T | 1 |
| Naka, T | 1 |
| Yamaue, H | 1 |
| Ishikawa, N | 1 |
| Oda, M | 1 |
| Kawaguchi, M | 1 |
| Tsunezuka, Y | 1 |
| Watanabe, G | 1 |
| Bhatia, M | 2 |
| Wong, FL | 1 |
| Fu, D | 1 |
| Lau, HY | 1 |
| Moochhala, SM | 1 |
| Moore, PK | 2 |
| Yamaki, E | 1 |
| Ogata, K | 1 |
| Hinohara, H | 1 |
| Kadoi, Y | 1 |
| Kunimoto, F | 1 |
| Kuwano, H | 1 |
| Fujita, Y | 1 |
| Fujino, Y | 1 |
| Maeda, Y | 1 |
| Uchiyama, A | 1 |
| Mashimo, T | 1 |
| Nishimura, M | 1 |
| Snyder, EM | 1 |
| Turner, ST | 1 |
| Johnson, BD | 1 |
| Zhang, H | 1 |
| Zhi, L | 1 |
| Moochhala, S | 1 |
| Sakashita, A | 1 |
| Nishimura, Y | 1 |
| Nishiuma, T | 1 |
| Takenaka, K | 1 |
| Kobayashi, K | 1 |
| Kotani, Y | 1 |
| Yokoyama, M | 1 |
| Mori, M | 1 |
| Iwasaki, T | 1 |
| Nakazawa, Y | 1 |
| Namba, Y | 1 |
| Niinaka, M | 1 |
| Yano, Y | 1 |
| Kitada, S | 1 |
| Kimura, H | 1 |
| Naka, N | 1 |
| Okada, T | 1 |
| Nakagawa, M | 1 |
| Maekura, R | 1 |
| Yokota, S | 1 |
| Herman, EH | 1 |
| Hasinoff, BB | 1 |
| Zhang, J | 1 |
| Raley, LG | 1 |
| Zhang, TM | 1 |
| Fukuda, Y | 1 |
| Ferrans, VJ | 1 |
| Guo, L | 1 |
| Yamaguchi, Y | 1 |
| Ikei, S | 1 |
| Sugita, H | 1 |
| Ogawa, M | 1 |
| Kobayashi, T | 2 |
| Hayano, T | 1 |
| Honda, T | 1 |
| Sekiguchi, M | 1 |
| Sakai, A | 1 |
| Yoshimura, K | 1 |
| Nakagawa, S | 1 |
| Koyama, S | 1 |
| Homma, T | 1 |
| Sakamaki, F | 1 |
| Ishizaka, A | 1 |
| Urano, T | 1 |
| Sayama, K | 1 |
| Nakamura, H | 1 |
| Terashima, T | 1 |
| Waki, Y | 1 |
| Tasaka, S | 1 |
| Hasegawa, N | 1 |
| Sato, K | 1 |
| Nakagawa, N | 1 |
| Obata, T | 1 |
| Kanazawa, M | 1 |
| Kitamura, S | 1 |
| Yamamoto, H | 1 |
| Kaneki, T | 1 |
| Hanaoka, M | 1 |
| Hagio, T | 1 |
| Nakao, S | 1 |
| Matsuoka, H | 1 |
| Matsumoto, S | 1 |
| Kawabata, K | 2 |
| Ohno, H | 1 |
| Varani, J | 1 |
| Ginsburg, I | 1 |
| Gibbs, DF | 1 |
| Mukhopadhyay, PS | 1 |
| Sulavik, C | 1 |
| Johnson, KJ | 1 |
| Weinberg, JM | 1 |
| Ryan, US | 1 |
| Ward, PA | 1 |
| Talbot, AR | 1 |
| Shiaw, MH | 1 |
| Huang, JS | 1 |
| Yang, SF | 1 |
| Goo, TS | 1 |
| Wang, SH | 1 |
| Chen, CL | 1 |
| Sanford, TR | 1 |
| Martinez, TT | 2 |
| Long, WC | 1 |
| Hiller, R | 1 |
| Brown, K | 1 |
| Suzuki, M | 1 |
| Sugitani, M | 1 |
| Imaki, K | 1 |
| Toda, M | 1 |
| Miyamoto, T | 1 |
| Adnet, JJ | 1 |
| Caulet, T | 1 |
| Legeay, G | 1 |
| Hopfner, C | 1 |
| Guenet, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Perioperative Application of Sivelestat Sodium in Acute Type A Aortic Dissection Patients With Preoperative Moderate to Severe Hypoxemia to Shorten the Duration of Postoperative Invasive Mechanical Ventilation[NCT05874700] | 30 participants (Anticipated) | Interventional | 2023-05-31 | Not yet recruiting | |||
| A Phase II Double Blind Randomized Controlled Trial of High Dose Vitamin B12 in Septic Shock[NCT03783091] | Phase 2 | 20 participants (Anticipated) | Interventional | 2019-08-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for glycine and Disease, Pulmonary
| Article | Year |
|---|---|
Bioactive extracellular matrix fragments in lung health and disease.
Topics: Animals; Chemotaxis; Collagen; Extracellular Matrix; Extracellular Matrix Proteins; Glycine; Humans; | 2016 |
[Pathophysiology of acute lung injury].
Topics: Acute Disease; Animals; Biomarkers; Capillary Permeability; Cell Adhesion Molecules; Clinical Trials | 1996 |
3 trials available for glycine and Disease, Pulmonary
| Article | Year |
|---|---|
Effect of High-Dose Cysteine Supplementation on Erythrocyte Glutathione: A Double-Blinded, Randomized Placebo-Controlled Pilot Study in Critically Ill Neonates.
Topics: Amino Acids; Chronic Disease; Critical Illness; Cysteine; Dietary Supplements; Dose-Response Relatio | 2016 |
Optimal period for the prophylactic administration of neutrophil elastase inhibitor for patients with esophageal cancer undergoing esophagectomy.
Topics: Aged; Esophageal Neoplasms; Esophagectomy; Female; Glycine; Humans; Lung Diseases; Male; Middle Aged | 2011 |
[Effects of neutrophil elastase inhibitor on postoperative cytokine levels in patients after esophagectomy].
Topics: Cytokines; Esophageal Neoplasms; Esophagectomy; Glycine; Humans; Interleukin-8; Leukocyte Elastase; | 2005 |
27 other studies available for glycine and Disease, Pulmonary
| Article | Year |
|---|---|
Engineering synthetic breath biomarkers for respiratory disease.
Topics: alpha 1-Antitrypsin Deficiency; Animals; Biomarkers; Breath Tests; Computer Simulation; Dose-Respons | 2020 |
Pulmonary inflammatory response from co-exposure to LPS and glyphosate.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Drug Interactions; Glycine; Glyphosate; Herbicides | 2021 |
The effect of sivelestat sodium on post-cardiopulmonary bypass acute lung injury in a neonatal piglet model.
Topics: Animals; Animals, Newborn; Cardiopulmonary Bypass; Disease Models, Animal; Drug Administration Sched | 2008 |
Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study.
Topics: Acute Disease; Analysis of Variance; Aortic Aneurysm, Thoracic; Aortic Dissection; Cardiopulmonary B | 2008 |
Sivelestat attenuates postoperative pulmonary dysfunction after total arch replacement under deep hypothermia.
Topics: Aged; Aged, 80 and over; Aorta, Thoracic; Aortic Aneurysm; Blood Vessel Prosthesis Implantation; C-R | 2008 |
Acute lung injury with alveolar hemorrhage due to a novel swine-origin influenza A (H1N1) virus.
Topics: Acute Lung Injury; Adult; Antiviral Agents; Female; Glycine; Hemorrhage; Humans; Influenza A Virus, | 2010 |
A survey of the effects of sivelestat sodium administration on patients with postoperative respiratory dysfunction.
Topics: Adult; Aged; Aged, 80 and over; Female; Glycine; Health Status; Health Surveys; Humans; Inflammation | 2010 |
The effects of a specific neutrophil elastase inhibitor (ONO-5046) in pulmonary ischemia-reperfusion injury.
Topics: Animals; Cardiac Output; Female; Glycine; Leukocyte Elastase; Lung Diseases; Lung Transplantation; O | 2003 |
Role of hydrogen sulfide in acute pancreatitis and associated lung injury.
Topics: Acute Disease; Alkynes; Amylases; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; C | 2005 |
Effect of Ono-EI-600 elastase inhibitor on high-tidal-volume-induced lung injury in rats.
Topics: Animals; Blood Gas Analysis; Cytokines; Glycine; Lung; Lung Diseases; Male; Pancreatic Elastase; Pro | 2006 |
Beta2-adrenergic receptor genotype and pulmonary function in patients with heart failure.
Topics: Adult; Arginine; Blood Pressure; Cardiac Output, Low; Case-Control Studies; DNA; Female; Glycine; Ho | 2006 |
Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB.
Topics: Alkynes; Animals; Cecum; Chemokines; Cystathionine gamma-Lyase; Cytokines; Disease Models, Animal; G | 2007 |
Neutrophil elastase inhibitor (sivelestat) attenuates subsequent ventilator-induced lung injury in mice.
Topics: Animals; Apoptosis; Blotting, Western; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Chemokines, CX | 2007 |
[A case of lung adenocarcinoma effectively treated with sivelestat and corcicosteroid for drug-induced lung disease due to gefitinib].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Gefitinib; Glycine; Humans; Lung Diseases; Lung Neoplas | 2008 |
Morphologic and morphometric evaluation of the effect of ICRF-187 on bleomycin-induced pulmonary toxicity.
Topics: Animals; Bleomycin; Ethylenediamines; Female; Glycine; Iron; Lung; Lung Diseases; Male; Mice; Mice, | 1995 |
Neutrophil elastase inhibitor (ONO-5046) prevents lung hemorrhage induced by lipopolysaccharide in rat model of cerulein pancreatitis.
Topics: Animals; Ceruletide; Disease Models, Animal; Drug Evaluation, Preclinical; Glycine; Hemorrhage; Leuk | 1995 |
Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bacteremia; Blood Gas Analysis; Endotoxins; Escherichia coli | 1994 |
Roles of neutrophil elastase and superoxide anion in leukotriene B4-induced lung injury in rabbit.
Topics: Animals; Capillary Permeability; Female; Glycine; In Vitro Techniques; Leukocyte Elastase; Leukotrie | 1994 |
Effect of a specific neutrophil elastase inhibitor, ONO-5046, on endotoxin-induced acute lung injury.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis; Escherichia coli; Glyc | 1996 |
Effects of lecithinized superoxide dismutase and a neutrophil elastase inhibitor (ONO-5046) on hyperoxic lung injury in rat.
Topics: Albumins; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Glycine; Hyperoxia; Leukocyte Elastase; | 2000 |
Inhibition of neutrophil elastase activity attenuates complement-mediated lung injury in the hamster.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Catalase; Complement Activation; Cric | 2001 |
Hydrogen peroxide-induced cell and tissue injury: protective effects of Mn2+.
Topics: Animals; Antioxidants; Bicarbonates; Capillary Permeability; Cells, Cultured; Cytotoxicity, Immunolo | 1991 |
Acute poisoning with a glyphosate-surfactant herbicide ('Roundup'): a review of 93 cases.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Central Nervous Sy | 1991 |
Comparison of the toxicology of the herbicide roundup by oral and pulmonary routes of exposure.
Topics: Administration, Inhalation; Administration, Oral; Animals; Glycine; Glyphosate; Herbicides; Lung; Lu | 1990 |
Oral and pulmonary toxicology of the surfactant used in roundup herbicide.
Topics: Administration, Oral; Animals; Glycine; Glyphosate; Herbicides; Intubation, Intratracheal; Lung Dise | 1991 |
ONO-5046, a novel inhibitor of human neutrophil elastase.
Topics: Animals; Binding, Competitive; Capillary Permeability; Cricetinae; Glycine; Guinea Pigs; Hemorrhage; | 1991 |
[Late lesions in the rat lung following whole-body irradiation. II. Morphological and cytochemical studies using electron microscopy].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Disease Models, Animal; Glycine; Histocytochemistry | 1970 |