Page last updated: 2024-10-18

glycine and Diabetes Mellitus

glycine has been researched along with Diabetes Mellitus in 44 studies

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen sulfide (H(2)S) has been traditionally known for its toxic effects on living organisms."1.35Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats. ( Cao, K; Duridanova, D; Jia, X; Wang, R; Wu, L; Yang, G; Yang, W, 2009)
"Insulin resistance was evaluated with fasting insulin, fasting glucose/insulin ratio, and homeostasis model assessment index for insulin resistance (HOMAIR)."1.33Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism. ( Gong, KB; Ku, DC; Kuo, TC; Liang, SF; Lin, TC; Wu, MJ; Yen, JM, 2006)
" Unlike morphine, CHF3381 chronic administration was not accompanied by the development of tolerance in the formalin test."1.32Antinociceptive activity of the N-methyl-D-aspartate receptor antagonist N-(2-Indanyl)-glycinamide hydrochloride (CHF3381) in experimental models of inflammatory and neuropathic pain. ( Barbieri, M; Bassani, F; Bergamaschi, M; Bolzoni, PT; Chamiot-Clerc, P; Maiorino, M; Pietra, C; Rondelli, I; Simonato, M; Villetti, G, 2003)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199024 (54.55)18.7374
1990's4 (9.09)18.2507
2000's10 (22.73)29.6817
2010's3 (6.82)24.3611
2020's3 (6.82)2.80

Authors

AuthorsStudies
Li, Y1
Yao, W1
Gao, Y1
Akizawa, T1
Tanaka-Amino, K1
Otsuka, T1
Yamaguchi, Y1
Gregory, A1
Yumnamcha, T1
Shawky, M1
Eltanani, S1
Naghdi, A1
Ross, BX1
Lin, X1
Ibrahim, AS1
Khera, PK1
Smith, EP1
Lindsell, CJ1
Rogge, MC1
Haggerty, S1
Wagner, DA1
Palascak, MB1
Mehta, S1
Hibbert, JM1
Joiner, CH1
Franco, RS1
Cohen, RM1
Wu, L1
Yang, W1
Jia, X1
Yang, G1
Duridanova, D1
Cao, K1
Wang, R1
Saigusa, D1
Suzuki, N1
Takahashi, M1
Shiba, K1
Tanaka, S1
Abe, T1
Hishinuma, T1
Tomioka, Y1
Lees, HJ1
Swann, JR1
Wilson, ID1
Nicholson, JK1
Holmes, E1
Villetti, G1
Bergamaschi, M1
Bassani, F1
Bolzoni, PT1
Maiorino, M1
Pietra, C1
Rondelli, I1
Chamiot-Clerc, P1
Simonato, M1
Barbieri, M1
Stefan, N1
Kovacs, P1
Stumvoll, M2
Hanson, RL1
Lehn-Stefan, A1
Permana, PA1
Baier, LJ1
Tataranni, PA1
Silver, K1
Bogardus, C1
Jellema, A1
Zeegers, MP1
Feskens, EJ1
Dagnelie, PC1
Mensink, RP1
Barbato, A1
Russo, P1
Venezia, A1
Strazzullo, V1
Siani, A1
Cappuccio, FP1
Chadarevian, R1
Foubert, L1
Beucler, I1
Kottler, ML1
Raisonnier, A1
Ajlouni, A1
Giral, P1
Turpin, G1
Bruckert, E1
BARNABEI, O1
MORSIANI, M1
FERRARI, R1
CHAO, PY1
KARAM, JH1
GRODSKY, GM1
KAESER, H1
Fritsche, A1
t'Hart, LM1
Machann, J1
Thamer, C1
Tschritter, O1
Van Haeften, TW1
Jacob, S1
Dekker, JM1
Maassen, JA1
Machicao, F1
Schick, F1
Heine, RJ1
Häring, H1
Oxombre, B1
Kouach, M1
Moerman, E1
Formstecher, P1
Laine, B1
Erlich, R1
Lin, TC1
Yen, JM1
Gong, KB1
Kuo, TC1
Ku, DC1
Liang, SF1
Wu, MJ1
Tokodi, I1
Pozsár, BI1
Szczeklik, A1
Pietoń, R1
Sieradzki, J1
Nizankowski, R1
Lever, M1
Sizeland, PC1
Bason, LM1
Hayman, CM1
Robson, RA1
Chambers, ST1
Gougeon, R1
Marliss, EB1
Jones, PJ1
Pencharz, PB1
Morais, JA1
Kasai, K1
Kobayashi, M1
Shimoda, SI1
Kadono, K1
Yamaguchi, T1
Tetsutani, T1
Yasunaga, K1
Matsumura, M1
Kuroda, M1
Itoh, M1
Hatakeyama, S1
Haruki, K1
Hirata, M1
Koni, I1
Takeda, R1
Tofuku, Y1
Molina, F1
Valencia, MC1
de la Torre, J1
Capitán-Vallvey, LF1
Wapnir, RA1
Gorback, MS1
Edwards, EH1
Ruderman, NB1
Berger, M1
Lal, D1
Schedl, HP1
Björkerud, S1
Björntorp, P1
Scherstén, T1
Vasiukova, EA1
Zefirova, GS1
Briskin, AI1
Beisswenger, PJ1
Spiro, RG1
Mertz, W1
Toepfer, EW1
Roginski, EE1
Polansky, MM1
Jerzykowski, T2
Matuszewski, W2
Nowak, S2
Otrzonsek, N2
Winter, R2
Hanoune, J1
Chambaut, AM1
Josipowicz, A1
Gylfe, E1
Lutkić, A1
Reipen, W1
Staib, W1
Matwiyoff, NA1
Ott, DG1
Kefalides, NA1
Manchester, KL1
Panksepp, J1
Grannis, GF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Measurement of Exhaled Lower Respiratory Carbon Monoxide and Correlation With Previous Measures of Red Cell Lifespan[NCT03288233]30 participants (Anticipated)Observational2015-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for glycine and Diabetes Mellitus

ArticleYear
Hippurate: the natural history of a mammalian-microbial cometabolite.
    Journal of proteome research, 2013, Apr-05, Volume: 12, Issue:4

    Topics: Age Factors; Animals; Atherosclerosis; Autistic Disorder; Benzoic Acid; Diabetes Mellitus; Diet; Fem

2013
Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies.
    Diabetologia, 2003, Volume: 46, Issue:7

    Topics: Amino Acid Substitution; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Genetic Carrier Scr

2003
[The possibilities to study the function of the human cells in clinical cell research].
    Lakartidningen, 1968, Jun-19, Volume: 65, Issue:25

    Topics: Adipose Tissue; Arteries; Arteriosclerosis; Diabetes Mellitus; Gallic Acid; Glucose; Glycine; Hepati

1968
[Anabolic steroids in the treatment of endocrine diseases].
    Terapevticheskii arkhiv, 1969, Volume: 41, Issue:4

    Topics: Adrenocorticotropic Hormone; Amino Acids; Anabolic Agents; Animals; Blood Glucose; Carbon Isotopes;

1969
Present knowledge of the role of chromium.
    Federation proceedings, 1974, Volume: 33, Issue:11

    Topics: Animals; Blood Glucose; Chromium; Cysteine; Diabetes Mellitus; Food Analysis; Glucose Tolerance Test

1974
Regulation by insulin of protein and amino acid metabolism.
    The Scientific basis of medicine annual reviews, 1971

    Topics: Amino Acids; Animals; Arteries; Carbon Isotopes; Cycloheximide; Diabetes Mellitus; Diaphragm; Glycin

1971

Trials

2 trials available for glycine and Diabetes Mellitus

ArticleYear
Clinical parameters among patients in Japan with anemia and non-dialysis-dependent chronic kidney disease with and without diabetes mellitus who received roxadustat.
    Clinical and experimental nephrology, 2022, Volume: 26, Issue:9

    Topics: Anemia; Cholesterol; Diabetes Mellitus; Glycated Hemoglobin; Glycine; Hemoglobins; Humans; Iron; Iso

2022
Abnormal glycine betaine content of the blood and urine of diabetic and renal patients.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Oct-14, Volume: 230, Issue:1

    Topics: Adult; Albuminuria; Betaine; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus; Fe

1994

Other Studies

36 other studies available for glycine and Diabetes Mellitus

ArticleYear
Effects of Tang Luo Ning on diabetic peripheral neuropathy in rats revealed by LC-MS metabolomics approach.
    Biomedical chromatography : BMC, 2022, Volume: 36, Issue:7

    Topics: Animals; Chromatography, Liquid; Citrates; Diabetes Mellitus; Diabetic Neuropathies; Glycine; Metabo

2022
The Warburg effect alters amino acid homeostasis in human retinal endothelial cells: implication for proliferative diabetic retinopathy.
    Scientific reports, 2023, 09-25, Volume: 13, Issue:1

    Topics: Diabetes Mellitus; Diabetic Retinopathy; Endothelial Cells; Fabaceae; Glycine; Homeostasis; Humans;

2023
Use of an oral stable isotope label to confirm variation in red blood cell mean age that influences HbA1c interpretation.
    American journal of hematology, 2015, Volume: 90, Issue:1

    Topics: Blood Glucose; Cell Survival; Cellular Senescence; Diabetes Mellitus; Erythrocytes; Female; Glycated

2015
Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:1

    Topics: Alkynes; Animals; Blood Glucose; Catalysis; Cystathionine gamma-Lyase; Diabetes Mellitus; Glycine; H

2009
Simultaneous determination of guanidinosuccinic acid and guanidinoacetic acid in urine using high performance liquid chromatography/tandem mass spectrometry.
    Analytica chimica acta, 2010, Sep-16, Volume: 677, Issue:2

    Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus; Diabetes Mel

2010
Antinociceptive activity of the N-methyl-D-aspartate receptor antagonist N-(2-Indanyl)-glycinamide hydrochloride (CHF3381) in experimental models of inflammatory and neuropathic pain.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: Animals; Carrageenan; Cold Temperature; Diabetes Mellitus; Disease Models, Animal; Drug Tolerance; E

2003
Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.
    Diabetes, 2003, Volume: 52, Issue:6

    Topics: Adult; Amino Acid Substitution; Animals; Arizona; Aspartic Acid; Base Sequence; Body Composition; Co

2003
Analysis of Gly40Ser polymorphism of the glucagon receptor (GCGR) gene in different ethnic groups.
    Journal of human hypertension, 2003, Volume: 17, Issue:8

    Topics: Adult; Asian People; Black People; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus; Female

2003
Lipoprotein lipase activity and common gene variants in severely hypertriglyceridemic patients with and without diabetes.
    Hormone research, 2003, Volume: 60, Issue:2

    Topics: Adult; Apolipoproteins; Asparagine; Aspartic Acid; Diabetes Complications; Diabetes Mellitus; Female

2003
[Peptic synthesis in alloxan diabetes].
    Bollettino della Societa italiana di biologia sperimentale, 1958, Apr-30, Volume: 34, Issue:8

    Topics: 4-Aminobenzoic Acid; Animals; Biochemical Phenomena; Diabetes Mellitus; Diabetes Mellitus, Experimen

1958
INSULIN I-131 BINDING IN SERUM FROM NORMAL AND DIABETIC SUBJECTS BY ULTRACENTRIFUGATION AND GEL FILTRATION.
    Diabetes, 1965, Volume: 14

    Topics: Antibodies; Bicarbonates; Blood Proteins; Chromatography, Gel; Diabetes Mellitus; Glycine; Humans; H

1965
[Glyco-glycinuric diabetes, a new familial syndrome].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1962, Volume: 17

    Topics: Body Fluids; Diabetes Mellitus; Glycine; Glycosuria; Humans; Syndrome

1962
The Gly482Ser variant in the peroxisome proliferator-activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2004, Volume: 112, Issue:5

    Topics: Adult; Amino Acid Substitution; Diabetes Mellitus; Female; Genotype; Germany; Glucose Clamp Techniqu

2004
The G115S mutation associated with maturity-onset diabetes of the young impairs hepatocyte nuclear factor 4alpha activities and introduces a PKA phosphorylation site in its DNA-binding domain.
    The Biochemical journal, 2004, Nov-01, Volume: 383, Issue:Pt. 3

    Topics: Age of Onset; Amino Acid Substitution; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; C

2004
American Diabetes Association - 65th Scientific Sessions. PPAR agents.
    IDrugs : the investigational drugs journal, 2005, Volume: 8, Issue:8

    Topics: Alkanesulfonates; Animals; Blood Glucose; Diabetes Mellitus; Glycine; Humans; Hypoglycemic Agents; O

2005
Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population- not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism.
    BMC medical genetics, 2006, Apr-07, Volume: 7

    Topics: Adolescent; Adult; Alanine; Amino Acid Substitution; Arginine; Diabetes Mellitus; Female; Glucose In

2006
Protein synthesis in leukocytes of diabetic and normal subjects.
    Nature, 1967, Jul-15, Volume: 215, Issue:5098

    Topics: Blood Proteins; Carbon Isotopes; Cysteine; Diabetes Mellitus; Glucose; Glycine; Humans; Leukocytes;

1967
The effects of prostacyclin on glycemia and insulin release in man.
    Prostaglandins, 1980, Volume: 19, Issue:6

    Topics: Adult; Aged; Arteriosclerosis; Blood Glucose; Buffers; Diabetes Mellitus; Epoprostenol; Female; Glyc

1980
Effect of exogenous insulin on protein metabolism with differing nonprotein energy intakes in Type 2 diabetes mellitus.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1998, Volume: 22, Issue:3

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dietary Proteins; Energy Intake;

1998
Stimulatory effect of glycine on human growth hormone secretion.
    Metabolism: clinical and experimental, 1978, Volume: 27, Issue:2

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Gastrectomy; Glycine; Growth Hormone; Humans;

1978
[A diabetic patient with empty sella syndrome accompanied by stimulated guanidinoacetic acid metabolism].
    Nihon Jinzo Gakkai shi, 1992, Volume: 34, Issue:11

    Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Empty Sella Syndrome; Female; Glyci

1992
[Guanidino compounds in the elderly].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1992, Volume: 29, Issue:4

    Topics: Aged; Aging; Bed Rest; Cerebrovascular Disorders; Diabetes Mellitus; Female; Glycine; Humans; Kidney

1992
Determination of acetoacetate in urine by solid-phase spectrophotometry.
    Journal of pharmaceutical and biomedical analysis, 1989, Volume: 7, Issue:7

    Topics: Acetoacetates; Calibration; Diabetes Mellitus; Glycine; Humans; Hydrogen-Ion Concentration; Ions; Ke

1989
Hyperglycemia and starvation: contrast in rat brain gluconeogenic amino acids and glycogen.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2

    Topics: Alanine; Animals; Blood Glucose; Brain Chemistry; Diabetes Mellitus; Gluconeogenesis; Glutamates; Gl

1972
The formation of glutamine and alanine in skeletal muscle.
    The Journal of biological chemistry, 1974, Sep-10, Volume: 249, Issue:17

    Topics: Alanine; Amino Acids; Animals; Arteries; Diabetes Mellitus; Electric Stimulation; Fasting; Female; G

1974
Intestinal adaptation in diabetes: amino acid absorption.
    The American journal of physiology, 1974, Volume: 227, Issue:4

    Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Chromatography, Paper; Diabetes M

1974
Studies on the human glomerular basement membrane. Composition, nature of the carbohydrate units and chemical changes in diabetes mellitus.
    Diabetes, 1973, Volume: 22, Issue:3

    Topics: Basement Membrane; Cystine; Diabetes Mellitus; Disaccharides; Fucose; Galactose; Glycine; Glycoprote

1973
Synthesis and decomposition of aminoacetone in sera of healthy subjects and of patients with various internal diseases.
    Polish medical journal, 1968, Volume: 7, Issue:6

    Topics: Acetone; Adult; Aged; Amino Acids; Arteriosclerosis; Chemical Phenomena; Chemistry; Chromatography,

1968
The glucose effect and cortisone action upon rat liver metabolism.
    Biochimica et biophysica acta, 1971, Aug-19, Volume: 244, Issue:2

    Topics: Acetates; Adenylyl Cyclases; Animals; Blood Glucose; Carbon Isotopes; Cortisone; Diabetes Mellitus;

1971
Changes of free amino acids in pancreatic beta-cells after starvation and substrate deprivation.
    Acta endocrinologica, 1974, Volume: 75, Issue:1

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography,

1974
Isolation of particulate glycogen by differential centrifugation.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1972, Volume: 353, Issue:10

    Topics: Animals; Buffers; Centrifugation; Centrifugation, Density Gradient; Chloroform; Cricetinae; Diabetes

1972
Stable isotope tracers in the life sciences and medicine.
    Science (New York, N.Y.), 1973, Sep-21, Volume: 181, Issue:4105

    Topics: Candida; Carbon Isotopes; Diabetes Mellitus; Eukaryota; Glucose; Glycine; Humans; Isotope Labeling;

1973
Biochemical properties of human glomerular basement membrane in normal and diabetic kidneys.
    Advances in metabolic disorders, 1973, Volume: 2

    Topics: Amino Acids; Animals; Basement Membrane; Carbohydrate Metabolism; Collagen; Diabetes Mellitus; Diabe

1973
Hypothalamic radioactivity after intragastric glucose- 14 C in rats.
    The American journal of physiology, 1972, Volume: 223, Issue:2

    Topics: Alanine; Animals; Carbon Isotopes; Diabetes Mellitus; Feeding Behavior; Food Deprivation; Glucose; G

1972
Plasma fibrinogen: determination, normal values, physiopathologic shifts, and fluctuations.
    Clinical chemistry, 1970, Volume: 16, Issue:6

    Topics: Blood Coagulation; Blood Coagulation Disorders; Chemical Precipitation; Densitometry; Diabetes Melli

1970
[Synthesis and decomposition of aminoacetone in serum of healthy persons and in various internal diseases].
    Polskie Archiwum Medycyny Wewnetrznej, 1968, Volume: 40, Issue:2

    Topics: Adult; Aged; Catalysis; Diabetes Mellitus; Female; Glycine; Humans; Kidney Diseases; Liver Cirrhosis

1968