glycine has been researched along with Dermatitis Herpetiformis in 2 studies
Dermatitis Herpetiformis: Rare, chronic, papulo-vesicular disease characterized by an intensely pruritic eruption consisting of various combinations of symmetrical, erythematous, papular, vesicular, or bullous lesions. The disease is strongly associated with the presence of HLA-B8 and HLA-DR3 antigens. A variety of different autoantibodies has been detected in small numbers in patients with dermatitis herpetiformis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silk, DB | 2 |
| Kumar, PJ | 1 |
| Perrett, D | 1 |
| Clark, ML | 2 |
| Dawson, AM | 1 |
| Kumar, P | 1 |
| Dawson, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute Glycine Pharmacodynamic Study[NCT01610011] | 21 participants (Actual) | Interventional | 2010-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Brain and plasma glycine levels are measured with proton magnetic resonance spectroscopy at 4T and analytically, respectively. Because glycine doses were limited to 30 g to avoid nausea and vomiting, some subjects with higher weights were administered lower doses per body weight of glycine (g/kg). Therefore, we corrected MRS data by the actual glycine dose administered (g/kg) to account for dosing differences. (NCT01610011)
Timeframe: For up to 2 hours
| Intervention | Percent brain glycine/creatine increase (Mean) |
|---|---|
| Glycine Administration Controls | 393 |
| Glycine Administration GLDC Mutation Subjects | 677 |
2 other studies available for glycine and Dermatitis Herpetiformis
| Article | Year |
|---|---|
Amino acid and peptide absorption in patients with coeliac disease and dermatitis herpetiformis.
Topics: Adult; Aged; Alanine; Amino Acids; Celiac Disease; Dermatitis Herpetiformis; Dipeptides; Glycine; Hu | 1974 |
Change in jejunal structure and function in dermatitis herpetiformis: effect of gluten-free diet and corticosteroids.
Topics: Adrenal Cortex Hormones; Alanine; Bicarbonates; Dermatitis Herpetiformis; Diet Therapy; Glucose; Glu | 1972 |