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glycine and Degenerative Diseases, Central Nervous System

glycine has been researched along with Degenerative Diseases, Central Nervous System in 17 studies

Research Excerpts

ExcerptRelevanceReference
"Conversely, cataplexy, one of the key symptoms of narcolepsy, is a striking sudden episode of muscle weakness triggered by emotions during wakefulness, and comparable to REM sleep atonia."2.47The neuronal network responsible for paradoxical sleep and its dysfunctions causing narcolepsy and rapid eye movement (REM) behavior disorder. ( Clément, O; Fort, P; Gervasoni, D; Léger, L; Luppi, PH; Peyron, C; Salvert, D; Sapin, E, 2011)
" So far it is not clear whether NMDA receptor antagonists including glycine antagonists would be suitable for chronic administration because of their effects on cognition, learning and motor function."2.40The glycine site on the NMDA receptor: structure-activity relationships and possible therapeutic applications. ( Dannhardt, G; Kohl, BK, 1998)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's7 (41.18)29.6817
2010's5 (29.41)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Lenard, AJ1
Zhou, Q1
Madreiter-Sokolowski, C1
Bourgeois, B1
Habacher, H1
Khanna, Y1
Madl, T1
Wright, SE1
Rodriguez, CM1
Monroe, J1
Xing, J1
Krans, A1
Flores, BN1
Barsur, V1
Ivanova, MI1
Koutmou, KS1
Barmada, SJ1
Todd, PK1
Ullah, R1
Jo, MH1
Riaz, M1
Alam, SI1
Saeed, K1
Ali, W1
Rehman, IU1
Ikram, M1
Kim, MO1
Heinß, N1
Sushkin, M1
Yu, M1
Lemke, EA1
Wu, YR1
Chen, CM1
Chao, CY1
Lyu, RK1
Lee-Chen, GJ1
Luppi, PH1
Clément, O1
Sapin, E1
Gervasoni, D1
Peyron, C1
Léger, L1
Salvert, D1
Fort, P1
Bech, S1
Nørremølle, A1
Winge, K1
Hasholt, L1
Tommerup, N1
Svenstrup, K1
Nielsen, JE1
Hjermind, LE1
Byrnes, KR1
Loane, DJ1
Stoica, BA1
Zhang, J1
Faden, AI1
Carta, E1
Chung, SK1
James, VM1
Robinson, A1
Gill, JL1
Remy, N1
Vanbellinghen, JF1
Drew, CJ1
Cagdas, S1
Cameron, D1
Cowan, FM1
Del Toro, M1
Graham, GE1
Manzur, AY1
Masri, A1
Rivera, S1
Scalais, E1
Shiang, R1
Sinclair, K1
Stuart, CA1
Tijssen, MA1
Wise, G1
Zuberi, SM1
Harvey, K1
Pearce, BR1
Topf, M1
Thomas, RH1
Supplisson, S1
Rees, MI1
Harvey, RJ1
Wang, YT1
Kuo, PH1
Chiang, CH1
Liang, JR1
Chen, YR1
Wang, S1
Shen, JC1
Yuan, HS1
Valera, E1
Fernández-Salguero, PM1
Planells-Cases, R1
Messeguer, A1
Van Den Nest, W1
Carreño, C1
Ferrer-Montiel, A1
Merino, JM1
Angusti, A1
Durini, E1
Vertuani, S1
Dalpiaz, A1
Ruffo, A1
Di Fabio, R1
Donati, D1
Pentassuglia, G1
Vitulli, G1
Barnaby, RJ1
Manfredini, S1
Liang, TW1
Truax, AC1
Trojanowski, JQ1
Lee, VM1
Stern, MB1
Kotzbauer, PT1
Dannhardt, G1
Kohl, BK1
Basile, AS1
Koustova, E1
Ioan, P1
Rizzoli, S1
Rogawski, MA1
Usherwood, PN1
Dringen, R1
Gutterer, JM1
Gros, C1
Hirrlinger, J1
Bilska, A1
Włodek, L1

Reviews

4 reviews available for glycine and Degenerative Diseases, Central Nervous System

ArticleYear
Multifunctionality of F-rich nucleoporins.
    Biochemical Society transactions, 2020, 12-18, Volume: 48, Issue:6

    Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; Animals; Cell Lineage; Cell Nucleus; Cilia; Cytop

2020
The neuronal network responsible for paradoxical sleep and its dysfunctions causing narcolepsy and rapid eye movement (REM) behavior disorder.
    Sleep medicine reviews, 2011, Volume: 15, Issue:3

    Topics: Amygdala; Animals; Brain; Brain Mapping; Cataplexy; Emotions; gamma-Aminobutyric Acid; Glutamine; Gl

2011
The glycine site on the NMDA receptor: structure-activity relationships and possible therapeutic applications.
    Current medicinal chemistry, 1998, Volume: 5, Issue:4

    Topics: Alzheimer Disease; Animals; Binding Sites; Cerebrovascular Disorders; Epilepsy; Glycine; Humans; Neu

1998
[Biologic properties of lipoic acid].
    Postepy higieny i medycyny doswiadczalnej, 2002, Volume: 56, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Aging; Animals; Antioxidants; Cataract; Decarboxylation; Diabeti

2002

Trials

1 trial available for glycine and Degenerative Diseases, Central Nervous System

ArticleYear
Mutations in the GlyT2 gene (SLC6A5) are a second major cause of startle disease.
    The Journal of biological chemistry, 2012, Aug-17, Volume: 287, Issue:34

    Topics: Animals; DNA Mutational Analysis; Female; Genetic Diseases, Inborn; Glycine; Glycine Plasma Membrane

2012

Other Studies

12 other studies available for glycine and Degenerative Diseases, Central Nervous System

ArticleYear
EGCG Promotes FUS Condensate Formation in a Methylation-Dependent Manner.
    Cells, 2022, 02-09, Volume: 11, Issue:4

    Topics: Arginine; Catechin; Glycine; Humans; Methylation; Neurodegenerative Diseases; Proteins; RNA-Binding

2022
CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins.
    Nucleic acids research, 2022, 08-26, Volume: 50, Issue:15

    Topics: Arginine; Ataxia; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glycine; Humans; Neurode

2022
Glycine, the smallest amino acid, confers neuroprotection against D-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain.
    Journal of neuroinflammation, 2020, Oct-15, Volume: 17, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Galactose; Glycine; JNK Mitogen

2020
Pantothenate kinase-associated neurodegeneration in two Taiwanese siblings: identification of a novel PANK2 gene mutation.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Apr-30, Volume: 24, Issue:6

    Topics: Aspartic Acid; DNA Mutational Analysis; Glycine; Humans; Magnetic Resonance Imaging; Male; Middle Ag

2009
The lrrk2 p.Gly2019Ser mutation is uncommon in a Danish cohort with various neurodegenerative disorders.
    Parkinsonism & related disorders, 2011, Volume: 17, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Denmark; Female; Genome-Wide Association Study; Glyc

2011
Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury.
    Journal of neuroinflammation, 2012, Feb-28, Volume: 9

    Topics: Animals; Brain Injuries; Calcium-Binding Proteins; Cognition Disorders; Diffusion Tensor Imaging; Di

2012
The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.
    The Journal of biological chemistry, 2013, Mar-29, Volume: 288, Issue:13

    Topics: Amino Acid Motifs; Amyloidogenic Proteins; Amyotrophic Lateral Sclerosis; Benzothiazoles; Chromatogr

2013
Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons.
    Neuromolecular medicine, 2002, Volume: 2, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Fetus; Glutamic

2002
Synthesis and biological evaluation of pro-drugs of GW196771, a potent glycine antagonist acting at the NMDA receptor.
    Farmaco (Societa chimica italiana : 1989), 2005, Volume: 60, Issue:5

    Topics: Animals; Drug Evaluation, Preclinical; Glycine; Indenes; Monosaccharides; Neurodegenerative Diseases

2005
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:5

    Topics: Arginine; Brain; DNA Mutational Analysis; Glycine; Humans; Iron; Isoleucine; Male; Middle Aged; Muta

2006
IgG isolated from LP-BM5 infected mouse brain activates ionotropic glutamate receptors.
    Neurobiology of disease, 2001, Volume: 8, Issue:6

    Topics: Animals; Autoantibodies; Autoimmune Diseases of the Nervous System; Brain; Cells, Cultured; Cerebral

2001
Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons.
    Journal of neuroscience research, 2001, Dec-01, Volume: 66, Issue:5

    Topics: Animals; CD13 Antigens; Cells, Cultured; Central Nervous System; Cysteine; Dipeptides; DNA, Compleme

2001