glycine has been researched along with Coronary Disease in 31 studies
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The overall aim of this study was to determine if adrenomedullin (AM) protects against myocardial ischaemia (MI)-induced arrhythmias via nitric oxide (NO) and peroxynitrite." | 7.73 | Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats. ( Kane, KA; Looi, YH; McPhaden, AR; Wainwright, CL, 2006) |
| "Higher activated partial thromboplastin time levels during inogatran treatment are related to increased risk of death, myocardial infarction or refractory angina." | 5.09 | Activated partial thromboplastin time and clinical outcome after thrombin inhibition in unstable coronary artery disease. ( Grip, L; Linder, R; Oldgren, J; Siegbahn, A; Wallentin, L, 1999) |
| "Circulating levels of glycine have previously been associated with lower incidence of coronary heart disease (CHD) and type 2 diabetes (T2D) but it remains uncertain if glycine plays an aetiological role." | 5.01 | Assessing the causal association of glycine with risk of cardio-metabolic diseases. ( Burgess, S; Butterworth, AS; Danesh, J; Day, FR; Erdmann, J; Forouhi, NG; Griffin, JL; Howson, JMM; Imamura, F; Karthikeyan, S; Khaw, KT; Koulman, A; Langenberg, C; Lotta, LA; Oliver-Williams, C; Schunkert, H; Scott, RA; Stewart, ID; Surendran, P; Wareham, NJ; Wittemans, LBL; Wood, AM; Zeng, L, 2019) |
| " The overall aim of this study was to determine if adrenomedullin (AM) protects against myocardial ischaemia (MI)-induced arrhythmias via nitric oxide (NO) and peroxynitrite." | 3.73 | Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats. ( Kane, KA; Looi, YH; McPhaden, AR; Wainwright, CL, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (38.71) | 18.7374 |
| 1990's | 8 (25.81) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 3 (9.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wittemans, LBL | 1 |
| Lotta, LA | 1 |
| Oliver-Williams, C | 1 |
| Stewart, ID | 1 |
| Surendran, P | 1 |
| Karthikeyan, S | 1 |
| Day, FR | 1 |
| Koulman, A | 1 |
| Imamura, F | 1 |
| Zeng, L | 1 |
| Erdmann, J | 1 |
| Schunkert, H | 1 |
| Khaw, KT | 1 |
| Griffin, JL | 1 |
| Forouhi, NG | 1 |
| Scott, RA | 1 |
| Wood, AM | 1 |
| Burgess, S | 1 |
| Howson, JMM | 1 |
| Danesh, J | 1 |
| Wareham, NJ | 1 |
| Butterworth, AS | 1 |
| Langenberg, C | 1 |
| Gao, H | 1 |
| Zhang, Z | 1 |
| Zhang, J | 1 |
| Zhao, N | 1 |
| Li, Q | 1 |
| Bai, M | 1 |
| Mencarelli, M | 1 |
| Zulian, A | 1 |
| Cancello, R | 1 |
| Alberti, L | 1 |
| Gilardini, L | 1 |
| Di Blasio, AM | 1 |
| Invitti, C | 1 |
| Oldgren, J | 2 |
| Wallentin, L | 3 |
| Grip, L | 3 |
| Linder, R | 2 |
| Nørgaard, BL | 2 |
| Siegbahn, A | 2 |
| Tan, JH | 1 |
| Low, PS | 1 |
| Tan, YS | 1 |
| Tong, MC | 1 |
| Saha, N | 1 |
| Yang, H | 1 |
| Heng, CK | 1 |
| MORRISON, LM | 1 |
| Vilahur, G | 1 |
| Baldellou, MI | 1 |
| Segalés, E | 1 |
| Salas, E | 1 |
| Badimon, L | 1 |
| Davis, BR | 1 |
| Arnett, DK | 1 |
| Boerwinkle, E | 2 |
| Ford, CE | 1 |
| Leiendecker-Foster, C | 1 |
| Miller, MB | 1 |
| Black, H | 1 |
| Eckfeldt, JH | 1 |
| Looi, YH | 1 |
| Kane, KA | 1 |
| McPhaden, AR | 1 |
| Wainwright, CL | 1 |
| Liedtke, AJ | 4 |
| Nellis, SH | 4 |
| Mjøs, OD | 1 |
| Korb, H | 1 |
| Hoeft, A | 1 |
| Hunneman, DH | 1 |
| Schraeder, R | 1 |
| Wolpers, HG | 1 |
| Wober, W | 1 |
| Hellige, G | 1 |
| Naqvi, N | 1 |
| Thompson, DS | 1 |
| Juul, SM | 1 |
| Jenkins, BS | 1 |
| Webb-Peploe, MM | 1 |
| Coltart, DJ | 1 |
| Darsee, JR | 1 |
| Kloner, RA | 1 |
| Burges, RA | 3 |
| Gardiner, DG | 3 |
| Higgins, AJ | 3 |
| Morville, M | 2 |
| Page, MG | 2 |
| Blackburn, KJ | 2 |
| Lüscher, MS | 1 |
| Thygesen, K | 2 |
| Ravkilde, J | 2 |
| Heickendorff, L | 1 |
| Antman, EM | 1 |
| Kastelein, JJ | 1 |
| Groenemeyer, BE | 1 |
| Hallman, DM | 1 |
| Henderson, H | 1 |
| Reymer, PW | 1 |
| Gagné, SE | 1 |
| Jansen, H | 1 |
| Seidell, JC | 1 |
| Kromhout, D | 1 |
| Jukema, JW | 1 |
| Bruschke, AV | 1 |
| Hayden, MR | 1 |
| Holmvang, L | 1 |
| Andersen, K | 2 |
| Dellborg, M | 2 |
| Clemmensen, P | 1 |
| Wagner, G | 1 |
| Grande, P | 1 |
| Abrahamsson, P | 2 |
| Näslund, U | 1 |
| Fischer-Hansen, J | 1 |
| Gundersen, T | 1 |
| Lehto, S | 2 |
| Pulkkinen, A | 1 |
| Viitanen, L | 1 |
| Kareinen, A | 1 |
| Laakso, M | 1 |
| Zheng, F | 1 |
| Chevalier, JA | 1 |
| Zhang, LQ | 1 |
| Virgil, D | 1 |
| Ye, SQ | 1 |
| Kwiterovich, PO | 1 |
| Nishiyama, Y | 1 |
| Nejima, J | 1 |
| Watanabe, A | 1 |
| Kotani, E | 1 |
| Sakai, N | 1 |
| Hatamochi, A | 1 |
| Shinkai, H | 1 |
| Kiuchi, K | 1 |
| Tamura, K | 1 |
| Shimada, T | 1 |
| Takano, T | 1 |
| Katayama, Y | 1 |
| Atkinson, L | 1 |
| Bergman, G | 1 |
| Jackson, N | 1 |
| Jewitt, DE | 1 |
| Metcalfe, JM | 1 |
| Renstrom, B | 2 |
| Molaparast-Saless, F | 1 |
| Goldsmith, JR | 1 |
| Landaw, SA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| GenHAT - Genetics of Hypertension Associated Treatments - Ancillary to ALLHAT[NCT00563901] | 37,939 participants (Actual) | Observational | 2000-09-30 | Completed | |||
| Are Serial Electrocardiograms Additive to SeriAl Second-generations Troponins in Predicting Acute CoronAry Syndromes in PatienTs With Undifferentiated cHest Pain (ASAP CATH) Study[NCT01953276] | 382 participants (Anticipated) | Observational | 2013-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for glycine and Coronary Disease
| Article | Year |
|---|---|
Assessing the causal association of glycine with risk of cardio-metabolic diseases.
Topics: Coronary Disease; Diabetes Mellitus, Type 2; Genetic Loci; Genetic Predisposition to Disease; Genome | 2019 |
7 trials available for glycine and Coronary Disease
| Article | Year |
|---|---|
Myocardial damage, inflammation and thrombin inhibition in unstable coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Antithrombins; C-Reactive Protein; Coronary Disease; Female; Fibrino | 2003 |
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Chlorthalido | 2007 |
Applicability of cardiac troponin T and I for early risk stratification in unstable coronary artery disease. TRIM Study Group. Thrombin Inhibition in Myocardial ischemia.
Topics: Adult; Aged; Antithrombins; Cohort Studies; Coronary Disease; Female; Glycine; Heparin; Humans; Male | 1997 |
Relative contributions of a single-admission 12-lead electrocardiogram and early 24-hour continuous electrocardiographic monitoring for early risk stratification in patients with unstable coronary artery disease.
Topics: Aged; Angina Pectoris; Angina, Unstable; Anticoagulants; Antithrombins; Coronary Disease; Electrocar | 1999 |
The impact of an end-point committee in a large multicentre, randomized, placebo-controlled clinical trial: results with and without the end-point committee's final decision on end-points.
Topics: Anticoagulants; Antithrombins; Coronary Disease; Data Collection; Double-Blind Method; Glycine; Hepa | 1999 |
Admission risk assessment by cardiac troponin T in unstable coronary artery disease: additional prognostic information from continuous ST segment monitoring. TRIM study group. Thrombin Inhibition in Myocardial Ischemia.
Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Antithrombins; Coronary Disease; Death, Sudden, Ca | 1999 |
Activated partial thromboplastin time and clinical outcome after thrombin inhibition in unstable coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Angina, Unstable; Antithrombins; Cause of Death; Coronary Disease; D | 1999 |
23 other studies available for glycine and Coronary Disease
| Article | Year |
|---|---|
Association of LT-alpha Ala252Gly gene polymorphism and the genetic predisposition of coronary heart disease in Chinese.
Topics: Alanine; Asian People; Case-Control Studies; China; Coronary Disease; Female; Genetic Predisposition | 2010 |
A novel missense mutation in the signal peptide of the human POMC gene: a possible additional link between early-onset type 2 diabetes and obesity.
Topics: Animals; Arginine; Cell Line, Tumor; Coronary Disease; Diabetes Mellitus, Type 2; Female; Genetic Lo | 2012 |
ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.
Topics: Alanine; Apolipoprotein A-I; Asian People; ATP Binding Cassette Transporter 1; ATP-Binding Cassette | 2003 |
Results of betaine treatment of atherosclerosis.
Topics: Arteriosclerosis; Atherosclerosis; Betaine; Coronary Disease; Fabaceae; Glycine | 1952 |
Inhibition of thrombosis by a novel platelet selective S-nitrosothiol compound without hemodynamic side effects.
Topics: Animals; Blood Platelets; Coronary Disease; Coronary Thrombosis; Coronary Vessels; Cyclic GMP; Femal | 2004 |
Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats.
Topics: Adrenomedullin; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; | 2006 |
Effects of reducing fatty acid metabolism on mechanical function in regionally ischemic hearts.
Topics: Animals; Coronary Disease; Fatty Acids; Glycine; Heart; Myocardium; Oxygen Consumption; Perfusion; P | 1984 |
Changes in myocardial substrate utilisation and protection of ischemic stressed myocardium by oxfenicine [(S)-4-hydroxyphenylglycine].
Topics: Animals; Carbohydrate Metabolism; Coronary Disease; Dogs; Fatty Acids, Nonesterified; Glycine; Hemod | 1984 |
Stimulation of myocardial lactate extraction by oxfenicine (L-hydroxyphenylglycine).
Topics: Adult; Coronary Angiography; Coronary Circulation; Coronary Disease; Glycine; Hemodynamics; Humans; | 1980 |
Dependency of location of salvageable myocardium on type of intervention.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Flurbiprofen; Glycine; Heart; Ibuprof | 1981 |
Protection of the ischaemic dog heart by oxfenicine.
Topics: Animals; Blood Glucose; Coronary Disease; Creatine Kinase; Dogs; Glycine; Heart; Isoenzymes; L-Lacta | 1981 |
Oxfenicine diverts rat muscle metabolism from fatty acid to carbohydrate oxidation and protects the ischaemic rat heart.
Topics: Animals; Coronary Disease; Diaphragm; Fatty Acids; Glycine; Lactates; Male; Myocardium; Oxidation-Re | 1980 |
Another chapter of the antithrombin story has been written...
Topics: Acute Disease; Antithrombins; Coronary Disease; Glycine; Heparin; Hirudin Therapy; Humans; Piperidin | 1997 |
The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group.
Topics: Asparagine; Coronary Disease; Genetic Heterogeneity; Genetic Variation; Glycine; Humans; Lipoprotein | 1998 |
Gly82Ser polymorphism of the receptor of advanced glycation end product gene is not associated with coronary heart disease in Finnish nondiabetic subjects or in patients with type 2 diabetes.
Topics: Amino Acid Substitution; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; | 2000 |
An HphI polymorphism in the E-selectin gene is associated with premature coronary artery disease.
Topics: Alleles; Apolipoproteins; Coronary Disease; Deoxyribonucleases, Type II Site-Specific; DNA Mutationa | 2001 |
Ehlers-Danlos syndrome type IV with a unique point mutation in COL3A1 and familial phenotype of myocardial infarction without organic coronary stenosis.
Topics: Adult; Aneurysm; Aspartic Acid; Collagen; Coronary Disease; Ehlers-Danlos Syndrome; Emphysema; Glyci | 2001 |
Protection against experimental myocardial ischaemia by L-4-hydroxy-phenylglycine, a new agent which alters myocardial metabolic balance in favour of carbohydrate utilisation [proceedings].
Topics: Animals; Carbohydrate Metabolism; Coronary Disease; Glycine; In Vitro Techniques; Myocardium; Rats | 1979 |
Potential protective value of enhanced myocardial carbohydrate utilisation with reduced free fatty acid uptake after UK 25842 in patients with coronary artery disease [proceedings].
Topics: Carbohydrate Metabolism; Coronary Disease; Fatty Acids, Nonesterified; Glycine; Humans; Myocardium | 1979 |
Mechanisms of substrate preference for oxidative metabolism during early myocardial reperfusion.
Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Coronary Disease; Fatty Acids; Glycine; Myocardial Repe | 1990 |
Metabolic oxidation of glucose during early myocardial reperfusion.
Topics: Animals; Coronary Disease; Fatty Acids; Glucose; Glycine; Glycogen; Heart; Myocardial Contraction; M | 1989 |
Effects of the fatty acid blocking agents, oxfenicine and 4-bromocrotonic acid, on performance in aerobic and ischemic myocardium.
Topics: Aerobiosis; Animals; Butyrates; Carnitine; Carnitine O-Palmitoyltransferase; Coronary Disease; Croto | 1987 |
Carbon monoxide and human health.
Topics: Accidents, Traffic; Aged; Air Pollution; Anemia, Hemolytic; Carbon; Carbon Isotopes; Carbon Monoxide | 1968 |