glycine has been researched along with Colorectal Neoplasms in 35 studies
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
Excerpt | Relevance | Reference |
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"We tested these hypotheses among participants in the Aspirin/Folate Polyp Prevention Study who were randomly assigned to placebo or to aspirin treatment (81 or 325 mg daily) and followed for 3 years for the occurrence of new adenomas." | 7.73 | Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention. ( Ahnen, DJ; Baron, JA; Barry, EL; Bhat, S; Burke, CA; Grau, MV; Haile, RW; O'Brien, TG; Sandler, RS, 2006) |
"Glycine has been shown to protect livers from CTx-induced injury and oxidative stress, and it reduces platelet aggregation and improves microperfusion." | 5.56 | Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats. ( Bausys, A; Feldbacher, N; Hoefler, G; Kolb-Lenz, D; Leber, B; Maneikyte, J; Schemmer, P; Stiegler, P; Strupas, K, 2020) |
"Fucoxanthinol (FxOH) is a strong anticancer metabolite of fucoxanthin that accumulates in abundance in edible brown algae and promises human health benefits." | 5.48 | Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells. ( Endo, T; Hamada, J; Kudoh, S; Maeda, H; Mima, M; Miyashita, K; Mutoh, M; Osada, K; Terasaki, M, 2018) |
"Glycine is a non-toxic amino acid with suspected anti-angiogenic effects." | 5.43 | Glycine inhibits angiogenesis in colorectal cancer: role of endothelial cells. ( Bruns, H; Kazanavicius, D; Saeedi, MA; Schemmer, P; Schultze, D; Strupas, K; Yamanaka, K, 2016) |
"We tested these hypotheses among participants in the Aspirin/Folate Polyp Prevention Study who were randomly assigned to placebo or to aspirin treatment (81 or 325 mg daily) and followed for 3 years for the occurrence of new adenomas." | 3.73 | Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention. ( Ahnen, DJ; Baron, JA; Barry, EL; Bhat, S; Burke, CA; Grau, MV; Haile, RW; O'Brien, TG; Sandler, RS, 2006) |
"Glycine has been shown to protect livers from CTx-induced injury and oxidative stress, and it reduces platelet aggregation and improves microperfusion." | 1.56 | Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats. ( Bausys, A; Feldbacher, N; Hoefler, G; Kolb-Lenz, D; Leber, B; Maneikyte, J; Schemmer, P; Stiegler, P; Strupas, K, 2020) |
"Fucoxanthinol (FxOH) is a strong anticancer metabolite of fucoxanthin that accumulates in abundance in edible brown algae and promises human health benefits." | 1.48 | Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells. ( Endo, T; Hamada, J; Kudoh, S; Maeda, H; Mima, M; Miyashita, K; Mutoh, M; Osada, K; Terasaki, M, 2018) |
" The sensitivity of human colorectal carcinoma cells to the PI Ixazomib was assessed via in vitro and in vivo dose-response experiments." | 1.48 | Non-invasive imaging of disrupted protein homeostasis induced by proteasome inhibitor treatment using chemical exchange saturation transfer MRI. ( Bradley, D; Chattopadhyay, N; Gibb, A; Golay, X; Johnson, SP; Lythgoe, MF; Pedley, RB; Ramasawmy, R; Taylor, V; Walker-Samuel, S; Zhu, Y, 2018) |
"Glycine is a non-toxic amino acid with suspected anti-angiogenic effects." | 1.43 | Glycine inhibits angiogenesis in colorectal cancer: role of endothelial cells. ( Bruns, H; Kazanavicius, D; Saeedi, MA; Schemmer, P; Schultze, D; Strupas, K; Yamanaka, K, 2016) |
"The increased risk of colorectal cancer in biallelic and monoallelic MYH gene mutation carriers was not consistently associated with the development of multiple adenomatous polyps." | 1.32 | Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk. ( Aronson, M; Cleary, SP; Cotterchio, M; Croitoru, ME; Di Nicola, N; Gallinger, S; Gryfe, R; Knight, J; Manno, M; Redston, M; Selander, T, 2004) |
"Once positive the circulating tumor cells persisted in subsequent multiple blood samples." | 1.31 | K-ras mutational analysis of polyclonal colorectal cancers identifies uniclonal circulating tumor cells. ( Krygier, S; Luchtefeld, MA; Senagore, AJ; Thebo, JS, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (11.43) | 18.2507 |
2000's | 10 (28.57) | 29.6817 |
2010's | 16 (45.71) | 24.3611 |
2020's | 5 (14.29) | 2.80 |
Authors | Studies |
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Zhu, C | 2 |
Huang, F | 1 |
Li, Y | 1 |
Zhou, K | 1 |
Xie, H | 1 |
Xia, L | 1 |
Xie, G | 1 |
Li, K | 1 |
Wu, JL | 1 |
Qin, B | 1 |
Fan, Z | 1 |
Tang, Q | 1 |
Lu, W | 1 |
Zhang, H | 2 |
Xing, F | 1 |
Meng, M | 1 |
Zou, S | 1 |
Wei, W | 1 |
Chen, H | 1 |
Cai, J | 2 |
Wang, H | 1 |
Fang, L | 2 |
Bian, X | 1 |
Chen, C | 1 |
Lan, P | 1 |
Ghesquière, B | 1 |
Lee, MH | 1 |
Maneikyte, J | 1 |
Bausys, A | 1 |
Leber, B | 2 |
Feldbacher, N | 1 |
Hoefler, G | 1 |
Kolb-Lenz, D | 1 |
Strupas, K | 4 |
Stiegler, P | 2 |
Schemmer, P | 4 |
Kvietkauskas, M | 1 |
Zitkute, V | 1 |
Rahmani, F | 1 |
Hashemzehi, M | 1 |
Avan, A | 1 |
Barneh, F | 1 |
Asgharzadeh, F | 1 |
Moradi Marjaneh, R | 1 |
Soleimani, A | 1 |
Parizadeh, M | 1 |
Ferns, GA | 1 |
Ghayour Mobarhan, M | 1 |
Ryzhikov, M | 1 |
Afshari, AR | 1 |
Ahmadian, MR | 1 |
Giovannetti, E | 1 |
Jafari, M | 1 |
Khazaei, M | 1 |
Hassanian, SM | 1 |
Chapelle, T | 1 |
Op de Beeck, B | 1 |
Driessen, A | 1 |
Roeyen, G | 1 |
Bracke, B | 1 |
Hartman, V | 1 |
Huyghe, I | 1 |
Morrison, S | 1 |
Ysebaert, D | 1 |
Francque, S | 1 |
Terasaki, M | 1 |
Mima, M | 1 |
Kudoh, S | 1 |
Endo, T | 1 |
Maeda, H | 1 |
Hamada, J | 1 |
Osada, K | 1 |
Miyashita, K | 1 |
Mutoh, M | 1 |
Zhu, Y | 1 |
Ramasawmy, R | 1 |
Johnson, SP | 1 |
Taylor, V | 1 |
Gibb, A | 1 |
Pedley, RB | 2 |
Chattopadhyay, N | 1 |
Lythgoe, MF | 1 |
Golay, X | 1 |
Bradley, D | 1 |
Walker-Samuel, S | 1 |
Yue, D | 1 |
Sun, X | 1 |
Smith, CG | 1 |
West, H | 1 |
Harris, R | 1 |
Idziaszczyk, S | 1 |
Maughan, TS | 1 |
Kaplan, R | 1 |
Richman, S | 1 |
Quirke, P | 1 |
Seymour, M | 1 |
Moskvina, V | 1 |
Steinke, V | 1 |
Propping, P | 1 |
Hes, FJ | 1 |
Wijnen, J | 1 |
Cheadle, JP | 1 |
Ho, AS | 1 |
Chen, CH | 1 |
Cheng, CC | 1 |
Wang, CC | 1 |
Lin, HC | 1 |
Luo, TY | 1 |
Lien, GS | 1 |
Chang, J | 1 |
Mazurenko, NN | 1 |
Gagarin, IM | 1 |
Tsyganova, IV | 1 |
Mochal'nikova, VV | 1 |
Breder, VV | 1 |
Geisel, D | 1 |
Lüdemann, L | 1 |
Gebauer, B | 1 |
Fröling, V | 1 |
Prasad, V | 1 |
Heimann, U | 1 |
Stockmann, M | 1 |
Malinowski, M | 1 |
Hamm, B | 1 |
Brenner, W | 1 |
Denecke, T | 1 |
Rocha, C | 1 |
Papon, L | 1 |
Cacheux, W | 1 |
Marques Sousa, P | 1 |
Lascano, V | 1 |
Tort, O | 1 |
Giordano, T | 1 |
Vacher, S | 1 |
Lemmers, B | 1 |
Mariani, P | 1 |
Meseure, D | 1 |
Medema, JP | 1 |
Bièche, I | 1 |
Hahne, M | 1 |
Janke, C | 1 |
Truant, S | 1 |
Baillet, C | 1 |
Deshorgue, AC | 1 |
Leteurtre, E | 1 |
Hebbar, M | 1 |
Ernst, O | 1 |
Huglo, D | 1 |
Pruvot, FR | 1 |
Bruns, H | 2 |
Kazanavicius, D | 1 |
Schultze, D | 1 |
Saeedi, MA | 1 |
Yamanaka, K | 1 |
Banerjee, K | 1 |
Das, S | 1 |
Majumder, S | 1 |
Majumdar, S | 1 |
Biswas, J | 1 |
Choudhuri, SK | 1 |
Berndt, SI | 1 |
Huang, WY | 1 |
Yeager, M | 1 |
Weissfeld, JL | 1 |
Chanock, SJ | 1 |
Hayes, RB | 1 |
Holdhoff, M | 1 |
Schmidt, K | 1 |
Donehower, R | 1 |
Diaz, LA | 1 |
Mikalauskas, S | 1 |
Mikalauskiene, L | 1 |
Nickkholgh, A | 1 |
Hoffmann, K | 1 |
Longerich, T | 1 |
Büchler, MW | 1 |
Zulhabri, O | 1 |
Rahman, J | 1 |
Ismail, S | 1 |
Isa, MR | 1 |
Wan Zurinah, WN | 1 |
Ferrari, P | 1 |
Nicolini, A | 1 |
Manca, ML | 1 |
Rossi, G | 1 |
Anselmi, L | 2 |
Conte, M | 1 |
Carpi, A | 1 |
Bonino, F | 1 |
Mao, C | 1 |
Huang, YF | 1 |
Yang, ZY | 1 |
Zheng, DY | 1 |
Chen, JZ | 1 |
Tang, JL | 1 |
Gismondi, V | 1 |
Meta, M | 1 |
Bonelli, L | 1 |
Radice, P | 1 |
Sala, P | 1 |
Bertario, L | 1 |
Viel, A | 1 |
Fornasarig, M | 1 |
Arrigoni, A | 1 |
Gentile, M | 1 |
Ponz de Leon, M | 1 |
Mareni, C | 1 |
Bruzzi, P | 1 |
Varesco, L | 1 |
Patel, O | 1 |
Dumesny, C | 1 |
Giraud, AS | 1 |
Baldwin, GS | 1 |
Shulkes, A | 1 |
Croitoru, ME | 1 |
Cleary, SP | 1 |
Di Nicola, N | 1 |
Manno, M | 1 |
Selander, T | 1 |
Aronson, M | 1 |
Redston, M | 1 |
Cotterchio, M | 1 |
Knight, J | 1 |
Gryfe, R | 1 |
Gallinger, S | 1 |
Menin, C | 1 |
Scaini, MC | 1 |
De Salvo, GL | 1 |
Biscuola, M | 1 |
Quaggio, M | 1 |
Esposito, G | 1 |
Belluco, C | 1 |
Montagna, M | 1 |
Agata, S | 1 |
D'Andrea, E | 1 |
Nitti, D | 1 |
Amadori, A | 1 |
Bertorelle, R | 1 |
Barry, EL | 1 |
Baron, JA | 1 |
Bhat, S | 1 |
Grau, MV | 1 |
Burke, CA | 1 |
Sandler, RS | 1 |
Ahnen, DJ | 1 |
Haile, RW | 1 |
O'Brien, TG | 1 |
Tuupanen, S | 1 |
Alhopuro, P | 1 |
Mecklin, JP | 1 |
Järvinen, H | 1 |
Aaltonen, LA | 1 |
Shanmugam, KS | 1 |
Brenner, H | 1 |
Hoffmeister, M | 1 |
Chang-Claude, J | 1 |
Burwinkel, B | 1 |
Fossum, B | 1 |
Gedde-Dahl, T | 1 |
Breivik, J | 1 |
Eriksen, JA | 1 |
Spurkland, A | 1 |
Thorsby, E | 1 |
Gaudernack, G | 1 |
Michael, NP | 1 |
Chester, KA | 1 |
Melton, RG | 1 |
Robson, L | 1 |
Nicholas, W | 1 |
Boden, JA | 1 |
Begent, RH | 1 |
Sherwood, RF | 1 |
Minton, NP | 1 |
Al-Mulla, F | 1 |
Going, JJ | 1 |
Sowden, ET | 1 |
Winter, A | 1 |
Pickford, IR | 1 |
Birnie, GD | 1 |
Conover, CD | 1 |
Greenwald, RB | 1 |
Pendri, A | 1 |
Gilbert, CW | 1 |
Shum, KL | 1 |
Thebo, JS | 1 |
Senagore, AJ | 1 |
Krygier, S | 1 |
Luchtefeld, MA | 1 |
1 review available for glycine and Colorectal Neoplasms
Article | Year |
---|---|
KRAS p.G13D mutation and codon 12 mutations are not created equal in predicting clinical outcomes of cetuximab in metastatic colorectal cancer: a systematic review and meta-analysis.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Antibodies, Monoclonal; Antibodies, Monoclo | 2013 |
1 trial available for glycine and Colorectal Neoplasms
Article | Year |
---|---|
Treatment of mild non-chemotherapy-induced iron deficiency anemia in cancer patients: comparison between oral ferrous bisglycinate chelate and ferrous sulfate.
Topics: Aged; Anemia, Iron-Deficiency; Breast Neoplasms; Colorectal Neoplasms; Dietary Supplements; Female; | 2012 |
33 other studies available for glycine and Colorectal Neoplasms
Article | Year |
---|---|
Distinct Urinary Metabolic Biomarkers of Human Colorectal Cancer.
Topics: Biomarkers; Biomarkers, Tumor; Colorectal Neoplasms; Glycine; Humans; Mass Spectrometry; Metabolomic | 2022 |
ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Epidermal Gr | 2020 |
Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms | 2020 |
Dietary Melatonin and Glycine Decrease Tumor Growth through Antiangiogenic Activity in Experimental Colorectal Liver Metastasis.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Colorectal Neoplasms; Diet; Glycine; Leukocyte C | 2021 |
Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Glycine; Humans; Sig | 2021 |
Estimation of the future remnant liver function is a better tool to predict post-hepatectomy liver failure than platelet-based liver scores.
Topics: Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasm | 2017 |
Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells.
Topics: Apoptosis; beta Carotene; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Epithelial-Mesenc | 2018 |
Non-invasive imaging of disrupted protein homeostasis induced by proteasome inhibitor treatment using chemical exchange saturation transfer MRI.
Topics: Amides; Amines; Animals; Apoptosis; Boron Compounds; Cell Line, Tumor; Cell Survival; Colorectal Neo | 2018 |
Ixazomib promotes CHOP-dependent DR5 induction and apoptosis in colorectal cancer cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boron Compounds; C | 2019 |
Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Alleles; Carcinoma; Case-Control Studies; Colorectal Neopla | 2013 |
Neutrophil elastase as a diagnostic marker and therapeutic target in colorectal cancers.
Topics: Amino Acid Sequence; Animals; Biomarkers, Tumor; Colorectal Neoplasms; Glycine; Humans; Leukocyte El | 2014 |
[The frequency and spectrum of KRAS mutations in metastatic colorectal cancer].
Topics: Adult; Aged; Amino Acid Substitution; Aspartic Acid; Colorectal Neoplasms; Female; Glycine; Humans; | 2013 |
Optimized separation of left and right liver lobe in dynamic (99m)Tc-mebrofenin hepatobiliary scintigraphy using a hybrid SPECT-CT scanner.
Topics: Aged; Aged, 80 and over; Aniline Compounds; Colorectal Neoplasms; Female; Glycine; Humans; Imino Aci | 2014 |
Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.
Topics: Animals; Blotting, Western; Carcinogens; Cell Proliferation; Cells, Cultured; Cilia; Colon; Colonic | 2014 |
Drop of Total Liver Function in the Interstages of the New Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Technique: Analysis of the "Auxiliary Liver" by HIDA Scintigraphy.
Topics: Aged; Aged, 80 and over; Aniline Compounds; Colorectal Neoplasms; Combined Modality Therapy; Emboliz | 2016 |
Glycine inhibits angiogenesis in colorectal cancer: role of endothelial cells.
Topics: Animals; Colorectal Neoplasms; Glycine; Human Umbilical Vein Endothelial Cells; Humans; Neovasculari | 2016 |
Modulation of cell death in human colorectal and breast cancer cells through a manganese chelate by involving GSH with intracellular p53 status.
Topics: Apoptosis; Breast Neoplasms; Chelating Agents; Colorectal Neoplasms; Female; Gene Expression Regulat | 2017 |
Genetic variants in frizzled-related protein (FRZB) and the risk of colorectal neoplasia.
Topics: Adenoma; Algorithms; Alleles; Amino Acid Substitution; Black or African American; Case-Control Studi | 2009 |
Analysis of circulating tumor DNA to confirm somatic KRAS mutations.
Topics: Amino Acid Substitution; Colorectal Neoplasms; DNA, Neoplasm; Flow Cytometry; Glycine; Humans; Male; | 2009 |
Dietary glycine protects from chemotherapy-induced hepatotoxicity.
Topics: Animals; Antineoplastic Agents; Camptothecin; Chemical and Drug Induced Liver Injury; Colorectal Neo | 2011 |
Predominance of G to A codon 12 mutation K-ras gene in Dukes' B colorectal cancer.
Topics: Adenine; Adenoma; Adult; Aged; Aged, 80 and over; Aspartic Acid; Carcinoma; Codon; Colorectal Neopla | 2012 |
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.
Topics: Adenine; Adenoma; Adenomatous Polyposis Coli; Adult; Aged; Aspartic Acid; Case-Control Studies; Colo | 2004 |
Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor.
Topics: Bombesin; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enzyme Activation; Focal Adhesion | 2004 |
Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk.
Topics: Adenomatous Polyposis Coli; Aspartic Acid; Base Pair Mismatch; Biomarkers, Tumor; Case-Control Studi | 2004 |
Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Colorectal Neoplasms; Female; Genes, p53; Genotype; Gly | 2006 |
Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention.
Topics: Adenoma; Adenomatous Polyposis Coli; Aged; Alanine; Anticarcinogenic Agents; Aspirin; Colorectal Neo | 2006 |
No evidence for association of NOD2 R702W and G908R with colorectal cancer.
Topics: Arginine; Colorectal Neoplasms; Female; Finland; Glycine; Humans; Male; Middle Aged; Mutation, Misse | 2007 |
The functional genetic variant Arg324Gly of frizzled-related protein is associated with colorectal cancer risk.
Topics: Amino Acid Substitution; Arginine; Case-Control Studies; Colorectal Neoplasms; Genetic Linkage; Gene | 2007 |
p21-ras-peptide-specific T-cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly-->Asp).
Topics: Adenocarcinoma; Amino Acid Sequence; Aspartic Acid; CD4-Positive T-Lymphocytes; CD8 Antigens; Cells, | 1994 |
In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein.
Topics: Animals; Artificial Gene Fusion; Blotting, Western; Carcinoembryonic Antigen; Chromatography, Affini | 1996 |
Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortality.
Topics: Adenocarcinoma; Adenoma; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Genes, ras; Genetic H | 1998 |
Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Drug Carriers; Glyci | 1998 |
K-ras mutational analysis of polyclonal colorectal cancers identifies uniclonal circulating tumor cells.
Topics: Aspartic Acid; Colorectal Neoplasms; Disease Progression; DNA Mutational Analysis; Genes, ras; Glyci | 2001 |