glycine has been researched along with Colonic Neoplasms in 35 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we evaluated the anti-inflammatory Trimethylglycine and the Signal transducer and activator of transcription (STAT6) inhibitor AS1517499, as possible adjuvants to 5-FU in already established cancers, using a model of colitis-associated colon cancer (CAC)." | 7.96 | Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis. ( Beristain-Terrazas, DL; Callejas, BE; Chirino, YI; Delgado-Buenrostro, NL; García-Castillo, V; Gutierrez-Cirlos, EB; León-Cabrera, SA; Mendoza-Rodríguez, MG; Meraz-Ríos, MA; Pérez-Plasencia, C; Rodríguez-Sosa, M; Sánchez-Barrera, CÁ; Terrazas, LI; Vaca-Paniagua, F, 2020) |
| "alpha-Methylacyl-CoA racemase (AMACR), an enzyme involved in oxidation of branched chain fatty acids and cholesterol metabolites, as well as ibuprofen metabolism, is overexpressed in colorectal adenomas and cancer." | 5.12 | Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. ( Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R, 2007) |
| " Here, we evaluated the anti-inflammatory Trimethylglycine and the Signal transducer and activator of transcription (STAT6) inhibitor AS1517499, as possible adjuvants to 5-FU in already established cancers, using a model of colitis-associated colon cancer (CAC)." | 3.96 | Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis. ( Beristain-Terrazas, DL; Callejas, BE; Chirino, YI; Delgado-Buenrostro, NL; García-Castillo, V; Gutierrez-Cirlos, EB; León-Cabrera, SA; Mendoza-Rodríguez, MG; Meraz-Ríos, MA; Pérez-Plasencia, C; Rodríguez-Sosa, M; Sánchez-Barrera, CÁ; Terrazas, LI; Vaca-Paniagua, F, 2020) |
| "HCT-116 colon cancer xenografts lacking mitochondrial 1C pathway activity generate the 1C units required for growth by cytosolic serine catabolism." | 1.43 | Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. ( Chen, L; Ducker, GS; Esposito, M; Ghergurovich, JM; Kang, Y; Morscher, RJ; Rabinowitz, JD; Teng, X, 2016) |
| "Ixazomib treatment resulted in significant metabolic regulation, and some of these changes were specific to KRAS WT tumors." | 1.42 | KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism. ( Amidon, B; Bannerman, B; Berger, AJ; Bernard, H; Chattopadhyay, N; Donelan, J; Galvin, K; Garnsey, J; Hales, P; Hather, G; Jordan, K; Koenig, E; Maldonado Lopez, A; Manfredi, M; Rhodes, N; Stringer, B; Tirrell, S; Xia, C; Yang, Y, 2015) |
| "The in vivo anticancer activity study with HT-29 colon cancer cell xenografted mice showed that the intratumorally injected PCC hydrogel inhibited the tumor growth more effectively relative to CPT alone (-29% vs." | 1.38 | Injectable poly(organophosphazene)-camptothecin conjugate hydrogels: synthesis, characterization, and antitumor activities. ( Cho, JK; Chun, C; Kuh, HJ; Song, SC, 2012) |
| "In two ulcerative colitis patients, a mutation was found in the Ki-ras gene (Gly --> Asp 12 and Gly --> Val 12), and in one patient, a mutation in exon 5 of the p53 gene." | 1.30 | Detection of Ki-ras mutations by PCR and differential hybridization and of p53 mutations by SSCP analysis in endoscopically obtained lavage solution from patients with long-standing ulcerative colitis. ( Heinzlmann, M; Lang, SM; Loeschke, K; Stratakis, DF; Teschauer, W, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.29) | 18.7374 |
| 1990's | 9 (25.71) | 18.2507 |
| 2000's | 8 (22.86) | 29.6817 |
| 2010's | 12 (34.29) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Mendoza-Rodríguez, MG | 1 |
| Sánchez-Barrera, CÁ | 1 |
| Callejas, BE | 1 |
| García-Castillo, V | 1 |
| Beristain-Terrazas, DL | 1 |
| Delgado-Buenrostro, NL | 1 |
| Chirino, YI | 1 |
| León-Cabrera, SA | 1 |
| Rodríguez-Sosa, M | 1 |
| Gutierrez-Cirlos, EB | 1 |
| Pérez-Plasencia, C | 1 |
| Vaca-Paniagua, F | 1 |
| Meraz-Ríos, MA | 1 |
| Terrazas, LI | 1 |
| Engür, S | 1 |
| Dikmen, M | 1 |
| Farhangian, H | 1 |
| Eslami Moghadam, M | 1 |
| Divsalar, A | 1 |
| Rahiminezhad, A | 1 |
| Zhao, Y | 1 |
| Wu, Z | 1 |
| Zhang, Y | 1 |
| Zhu, L | 1 |
| Gonsalves, WI | 1 |
| Mahoney, MR | 1 |
| Sargent, DJ | 1 |
| Nelson, GD | 1 |
| Alberts, SR | 1 |
| Sinicrope, FA | 1 |
| Goldberg, RM | 1 |
| Limburg, PJ | 1 |
| Thibodeau, SN | 1 |
| Grothey, A | 1 |
| Hubbard, JM | 1 |
| Chan, E | 1 |
| Nair, S | 1 |
| Berenberg, JL | 1 |
| McWilliams, RR | 1 |
| Rocha, C | 1 |
| Papon, L | 1 |
| Cacheux, W | 1 |
| Marques Sousa, P | 1 |
| Lascano, V | 1 |
| Tort, O | 1 |
| Giordano, T | 1 |
| Vacher, S | 1 |
| Lemmers, B | 1 |
| Mariani, P | 1 |
| Meseure, D | 1 |
| Medema, JP | 1 |
| Bièche, I | 1 |
| Hahne, M | 1 |
| Janke, C | 1 |
| Fan, K | 1 |
| Li, N | 1 |
| Qi, J | 1 |
| Yin, P | 1 |
| Zhao, C | 1 |
| Wang, L | 1 |
| Li, Z | 1 |
| Zha, X | 1 |
| Chattopadhyay, N | 1 |
| Berger, AJ | 1 |
| Koenig, E | 1 |
| Bannerman, B | 1 |
| Garnsey, J | 1 |
| Bernard, H | 1 |
| Hales, P | 1 |
| Maldonado Lopez, A | 1 |
| Yang, Y | 1 |
| Donelan, J | 1 |
| Jordan, K | 1 |
| Tirrell, S | 1 |
| Stringer, B | 1 |
| Xia, C | 1 |
| Hather, G | 1 |
| Galvin, K | 1 |
| Manfredi, M | 1 |
| Rhodes, N | 1 |
| Amidon, B | 1 |
| Ducker, GS | 1 |
| Chen, L | 1 |
| Morscher, RJ | 1 |
| Ghergurovich, JM | 1 |
| Esposito, M | 1 |
| Teng, X | 1 |
| Kang, Y | 1 |
| Rabinowitz, JD | 1 |
| Riscal, R | 1 |
| Schrepfer, E | 1 |
| Arena, G | 1 |
| Cissé, MY | 1 |
| Bellvert, F | 1 |
| Heuillet, M | 1 |
| Rambow, F | 1 |
| Bonneil, E | 1 |
| Sabourdy, F | 1 |
| Vincent, C | 1 |
| Ait-Arsa, I | 1 |
| Levade, T | 1 |
| Thibaut, P | 1 |
| Marine, JC | 1 |
| Portais, JC | 1 |
| Sarry, JE | 1 |
| Le Cam, L | 1 |
| Linares, LK | 1 |
| Liu, Y | 1 |
| Wang, SQ | 1 |
| Long, YH | 1 |
| Chen, S | 1 |
| Li, YF | 1 |
| Zhang, JH | 1 |
| Li, Y | 1 |
| Tan, T | 1 |
| Zheng, J | 1 |
| Zhang, C | 1 |
| Cho, JK | 1 |
| Chun, C | 1 |
| Kuh, HJ | 1 |
| Song, SC | 1 |
| Duan, X | 1 |
| Li, H | 1 |
| Chen, H | 1 |
| Wang, Q | 1 |
| Gross, I | 1 |
| Lhermitte, B | 1 |
| Domon-Dell, C | 1 |
| Duluc, I | 1 |
| Martin, E | 1 |
| Gaiddon, C | 1 |
| Kedinger, M | 1 |
| Freund, JN | 1 |
| Houli, N | 1 |
| Loh, SW | 1 |
| Giraud, AS | 1 |
| Baldwin, GS | 2 |
| Shulkes, A | 2 |
| Chattopadhyay, S | 1 |
| Zhao, R | 1 |
| Krupenko, SA | 1 |
| Krupenko, N | 1 |
| Goldman, ID | 1 |
| Arakawa, Y | 1 |
| Suzuki, H | 1 |
| Saito, S | 1 |
| Yamada, H | 1 |
| Daugherty, SE | 1 |
| Platz, EA | 1 |
| Shugart, YY | 1 |
| Fallin, MD | 1 |
| Isaacs, WB | 1 |
| Chatterjee, N | 1 |
| Welch, R | 1 |
| Huang, WY | 1 |
| Hayes, RB | 1 |
| Wilson, KJ | 1 |
| Witter, DJ | 1 |
| Grimm, JB | 1 |
| Siliphaivanh, P | 1 |
| Otte, KM | 1 |
| Kral, AM | 1 |
| Fleming, JC | 1 |
| Harsch, A | 1 |
| Hamill, JE | 1 |
| Cruz, JC | 1 |
| Chenard, M | 1 |
| Szewczak, AA | 1 |
| Middleton, RE | 1 |
| Hughes, BL | 1 |
| Dahlberg, WK | 1 |
| Secrist, JP | 1 |
| Miller, TA | 1 |
| Claque, MB | 1 |
| Carmichael, MJ | 1 |
| Satoh, M | 1 |
| Cherian, MG | 1 |
| Imura, N | 1 |
| Shimizu, H | 1 |
| Gan, LS | 1 |
| Niederer, T | 1 |
| Eads, C | 1 |
| Thakker, D | 1 |
| Capaccioli, S | 1 |
| Di Pasquale, G | 1 |
| Mini, E | 1 |
| Mazzei, T | 1 |
| Quattrone, A | 1 |
| Furuishi, K | 1 |
| Misumi, S | 1 |
| Shoji, S | 1 |
| Lang, SM | 1 |
| Heinzlmann, M | 1 |
| Stratakis, DF | 1 |
| Teschauer, W | 1 |
| Loeschke, K | 1 |
| Hofman, P | 1 |
| Selva, E | 1 |
| Le Negrate, G | 1 |
| d'Andrea, L | 1 |
| Guérin, S | 1 |
| Rossi, B | 1 |
| Auberger, P | 1 |
| Paranavitana, CM | 1 |
| Lozonschi, L | 1 |
| Sunamura, M | 1 |
| Kobari, M | 1 |
| Egawa, S | 1 |
| Ding, L | 1 |
| Matsuno, S | 1 |
| Aly, A | 1 |
| Saravis, CA | 2 |
| Oh, SK | 2 |
| Pusztaszeri, G | 2 |
| Doos, WG | 1 |
| Zamcheck, N | 2 |
| Doos, W | 1 |
| Smith, TK | 1 |
| Gibson, CL | 1 |
| Howlin, BJ | 1 |
| Pratt, JM | 1 |
| Striebel, JP | 1 |
| Saeger, HD | 1 |
| Ritz, R | 1 |
| Leweling, H | 1 |
| Holm, E | 1 |
| Bibby, MC | 1 |
| Double, JA | 1 |
1 trial available for glycine and Colonic Neoplasms
| Article | Year |
|---|---|
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.
Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies | 2007 |
34 other studies available for glycine and Colonic Neoplasms
| Article | Year |
|---|---|
Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis.
Topics: Adjuvants, Pharmaceutic; Animals; Apoptosis; beta Catenin; Cadherins; Carcinogenesis; Cell Adhesion | 2020 |
The evaluation of the anti-cancer activity of ixazomib on Caco2 colon solid tumor cells, comparison with bortezomib.
Topics: Adenocarcinoma; Antineoplastic Agents; Boron Compounds; Bortezomib; Caco-2 Cells; Caspase 3; Colonic | 2017 |
Anticancer activity of novel amino acid derivative of palladium complex with phendione ligand against of human colon cancer cell line.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Coo | 2017 |
HY-1 induces G(2)/M cell cycle arrest in human colon cancer cells through the ATR-Chk1-Cdc25C and Weel pathways.
Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; CDC2 Protein Kinase; cdc25 Phosphatases; | 2013 |
Patient and tumor characteristics and BRAF and KRAS mutations in colon cancer, NCCTG/Alliance N0147.
Topics: Adult; Aged; Aspartic Acid; Clinical Trials, Phase III as Topic; Colonic Neoplasms; DNA Mismatch Rep | 2014 |
Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon.
Topics: Animals; Blotting, Western; Carcinogens; Cell Proliferation; Cells, Cultured; Cilia; Colon; Colonic | 2014 |
Wnt/β-catenin signaling induces the transcription of cystathionine-γ-lyase, a stimulator of tumor in colon cancer.
Topics: Alkynes; Animals; Binding Sites; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neopla | 2014 |
KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.
Topics: Amino Acids; Animals; Antineoplastic Agents; Boron Compounds; Carcinoma, Non-Small-Cell Lung; Cell L | 2015 |
Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.
Topics: Aminoimidazole Carboxamide; Carbon; Cell Compartmentation; Cell Proliferation; Colonic Neoplasms; CR | 2016 |
Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.
Topics: Activating Transcription Factor 4; Animals; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell P | 2016 |
KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway.
Topics: A549 Cells; Animals; Antineoplastic Agents, Immunological; Cell Line; Cell Line, Tumor; Cell Prolife | 2016 |
[A comparison on radiochemical behavior and biological property of antisense oligonucleotide labeled with technetium-99m by two methods: NHS-MAG3 versus SHNHP].
Topics: Animals; Colonic Neoplasms; Glycine; Humans; Isotope Labeling; Mice; Mice, Inbred BALB C; Niacinamid | 2008 |
Injectable poly(organophosphazene)-camptothecin conjugate hydrogels: synthesis, characterization, and antitumor activities.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Drug Stability; D | 2012 |
Discrimination of colon cancer stem cells using noncanonical amino acid.
Topics: Alkynes; Cell Separation; Colonic Neoplasms; Glycine; HCT116 Cells; Humans; Neoplastic Stem Cells | 2012 |
Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.
Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Substitution; Animals | 2005 |
Mitogenic effects of both amidated and glycine-extended gastrin-releasing peptide in defunctioned and azoxymethane-treated rat colon in vivo.
Topics: Animals; Azoxymethane; Cell Proliferation; Colon; Colonic Neoplasms; Gastrin-Releasing Peptide; Glyc | 2006 |
The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line.
Topics: Amino Acid Substitution; Antineoplastic Agents; Arginine; Carrier Proteins; Cell Line, Tumor; Coloni | 2006 |
Novel missense mutation of the DNA topoisomerase I gene in SN-38-resistant DLD-1 cells.
Topics: Amino Acid Substitution; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Colonic | 2006 |
Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1).
Topics: Acetylation; Amides; Animals; Cell Proliferation; Colonic Neoplasms; Dogs; Enzyme Inhibitors; ERG1 P | 2008 |
15N glycine metabolism.
Topics: Colonic Neoplasms; Glycine; Humans; Kinetics; Rectal Neoplasms | 1982 |
Modulation of resistance to anticancer drugs by inhibition of metallothionein synthesis.
Topics: Alkynes; Animals; Cisplatin; Colonic Neoplasms; Cysteine; Doxorubicin; Drug Resistance; Female; Fibr | 1994 |
Evidence for predominantly paracellular transport of thyrotropin-releasing hormone across CACO-2 cell monolayers.
Topics: 2,4-Dinitrophenol; Adenocarcinoma; Amiloride; Azides; Biological Transport; Cell Line; Cell Membrane | 1993 |
Cationic lipids improve antisense oligonucleotide uptake and prevent degradation in cultured cells and in human serum.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Base Sequence; Biological Transport; Cell Line; Colonic Neoplasm | 1993 |
A novel monoclonal antibody to N-myristoyl glycine moiety found a new N-myristoylated HIV-1 p28gag protein in HIV-1-infected cells.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibody Specificity; Avian Sarcoma Viruses; Cells, | 1996 |
Detection of Ki-ras mutations by PCR and differential hybridization and of p53 mutations by SSCP analysis in endoscopically obtained lavage solution from patients with long-standing ulcerative colitis.
Topics: Aspartic Acid; Biopsy; Case-Control Studies; Cell Transformation, Neoplastic; Codon; Colitis, Ulcera | 1997 |
CD10 inhibitors increase f-Met-Leu-Phe-induced neutrophil transmigration.
Topics: Benzylidene Compounds; Chemotaxis, Leukocyte; Colonic Neoplasms; Drug Synergism; Enzyme Inhibitors; | 1998 |
Non-radioactive detection of K-ras mutations by nested allele specific PCR and oligonucleotide hybridization.
Topics: Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Breast Neoplasms; Codon; Colonic Neoplasms | 1998 |
Controlling tumor angiogenesis and metastasis of C26 murine colon adenocarcinoma by a new matrix metalloproteinase inhibitor, KB-R7785, in two tumor models.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Glycine; Hydroxamic Acids; Lung Neoplasms; Male; Metallo | 1999 |
Short term infusion of glycine-extended gastrin(17) stimulates both proliferation and formation of aberrant crypt foci in rat colonic mucosa.
Topics: Animals; Azoxymethane; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Gastrins; Glycine; Horm | 2001 |
Tissue localization of zinc glycinate marker and carcinoembryonic antigen by immunofluorescence. I. Preparation of antisera against the zinc glycinate marker.
Topics: Animals; Antibodies, Neoplasm; Carcinoembryonic Antigen; Chromatography, Gel; Colonic Neoplasms; Ele | 1978 |
Present status of the zinc glycinate marker (ZGM).
Topics: Antigens, Neoplasm; Chromatography, Gel; Colonic Neoplasms; Glycine; Humans; Neoplasm Metastasis; Ne | 1978 |
Active transport of amino acids by gamma-glutamyl transpeptidase through Caco-2 cell monolayers.
Topics: Amino Acids; Biological Transport; Biological Transport, Active; Cell Line; Cell Membrane; Colonic N | 1991 |
[Amino acid uptake and release by colorectal cancer in man].
Topics: Aged; Amino Acids; Colonic Neoplasms; Female; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; | 1986 |
Activity of N-[N'-(2-chloroethyl)-N'-nitrosocarbamoyl]-alanine and derivatives against transplantable adenocarcinomata of the mouse colon (MAC).
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alanine; Animals; Antineoplastic Agents; Colonic Neoplasms; D | 1986 |