glycine has been researched along with Clasp-Knife Spasticity in 20 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether the naturally occurring amino acid threonine, a potential precursor for glycine biosynthesis in the spinal cord, has an effect on spasticity in multiple sclerosis, 26 ambulatory patients were entered into a randomized crossover trial." | 9.07 | An antispasticity effect of threonine in multiple sclerosis. ( Doolittle, TH; Growdon, J; Hauser, SL; Lehrich, JR; Lopez-Bresnahan, M; Schoenfeld, D; Shahani, B; Shih, VE, 1992) |
| "To determine whether the naturally occurring amino acid threonine, a potential precursor for glycine biosynthesis in the spinal cord, has an effect on spasticity in multiple sclerosis, 26 ambulatory patients were entered into a randomized crossover trial." | 5.07 | An antispasticity effect of threonine in multiple sclerosis. ( Doolittle, TH; Growdon, J; Hauser, SL; Lehrich, JR; Lopez-Bresnahan, M; Schoenfeld, D; Shahani, B; Shih, VE, 1992) |
| "The term cerebral palsy is restricted to non-progressive disorders of motor function, already observed at an early age and due to cerebral lesions." | 2.37 | [Functional neurosurgery of cerebral palsy]. ( Alexandre, F; Angelini, L; Benezech, J; Broggi, G; Claverie, P; Deonna, T; Frerebeau, P; Lazorthes, Y; Siegfried, J; Verdie, JC, 1985) |
| "Spinal cord injury-induced spasticity, in the tail musculature, does not appear to involve either an increase in monosynaptic glutamatergic inputs from myelinated afferents or a decrease in glycinergic inputs to sacrocaudal motoneurons." | 1.34 | VGLUT1 and GLYT2 labeling of sacrocaudal motoneurons in the spinal cord injured spastic rat. ( Kitzman, P, 2007) |
| "Thus, in spastic, GlyRs are functionally normal but reduced in number, whereas in spasmodic, GlyR kinetics is faster." | 1.33 | Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator. ( Callister, RJ; Graham, BA; Margrie, TW; Sah, P; Schofield, PR, 2006) |
| "However, the overall structure of the spastic mutant retina was not disrupted because the distribution and intensity of both a presynaptic marker (synaptophysin) and a marker for the rod bipolar cell (protein kinase C) in the mutant retina were indistinguishable from those in normal retinas." | 1.29 | Glycine receptors in the retinas of normal and spastic mutant mice. ( Becker, CM; Grünert, U; Kirsch, J; Pinto, LH; Studholme, K; Yazulla, S, 1994) |
| "The role of glycine in spasticity and spinal shock was explored further in rabbits with ischemic spinal cord injuries that produced spastic paraparesis or flaccid paraplegia." | 1.29 | The role of glycine in spinal shock. ( Goodman, JC; Robertson, CS; Simpson, RK, 1996) |
| "Some of the clinical signs of spasticity improved in the animals injected with glycine compared to the saline-injected controls." | 1.26 | Effects of glycine administration on canine experimental spinal spasticity and the levels of glycine, glutamate, and aspartate in the lumbar spinal cord. ( Campbell, RL; Galvin, MR; Hall, PV; Jones, AR; Smith, JE, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, H | 1 |
| Peng, T | 1 |
| Yang, X | 1 |
| Liu, L | 1 |
| Xu, Y | 1 |
| Zhao, Y | 1 |
| Huang, S | 1 |
| Fu, C | 1 |
| Huang, Y | 1 |
| Zhou, H | 1 |
| Li, J | 1 |
| He, L | 1 |
| Wang, W | 1 |
| Niu, H | 1 |
| Xu, K | 1 |
| Kopach, O | 1 |
| Medvediev, V | 1 |
| Krotov, V | 1 |
| Borisyuk, A | 1 |
| Tsymbaliuk, V | 1 |
| Voitenko, N | 1 |
| Boulenguez, P | 2 |
| Liabeuf, S | 2 |
| Bos, R | 1 |
| Bras, H | 1 |
| Jean-Xavier, C | 1 |
| Brocard, C | 1 |
| Stil, A | 1 |
| Darbon, P | 1 |
| Cattaert, D | 1 |
| Delpire, E | 1 |
| Marsala, M | 1 |
| Vinay, L | 2 |
| CHAI, CK | 1 |
| ROBERTS, E | 1 |
| SIDMAN, RL | 1 |
| Zafonte, R | 1 |
| Lombard, L | 1 |
| Elovic, E | 1 |
| Graham, BA | 1 |
| Schofield, PR | 1 |
| Sah, P | 1 |
| Margrie, TW | 1 |
| Callister, RJ | 1 |
| Kitzman, P | 1 |
| Pinto, LH | 1 |
| Grünert, U | 1 |
| Studholme, K | 1 |
| Yazulla, S | 1 |
| Kirsch, J | 1 |
| Becker, CM | 1 |
| Simpson, RK | 2 |
| Gondo, M | 1 |
| Robertson, CS | 2 |
| Goodman, JC | 2 |
| Mertens, P | 1 |
| Ghaemmaghami, C | 1 |
| Bert, L | 1 |
| Perret-Liaudet, A | 1 |
| Sindou, M | 1 |
| Renaud, B | 1 |
| Hall, PV | 2 |
| Smith, JE | 2 |
| Campbell, RL | 2 |
| Felten, DL | 1 |
| Aprison, MH | 1 |
| Galvin, MR | 1 |
| Jones, AR | 1 |
| Hauser, SL | 1 |
| Doolittle, TH | 1 |
| Lopez-Bresnahan, M | 1 |
| Shahani, B | 1 |
| Schoenfeld, D | 1 |
| Shih, VE | 1 |
| Growdon, J | 1 |
| Lehrich, JR | 1 |
| Dietz, V | 1 |
| Davidoff, RA | 2 |
| Siegfried, J | 1 |
| Lazorthes, Y | 1 |
| Broggi, G | 1 |
| Claverie, P | 1 |
| Deonna, T | 1 |
| Frerebeau, P | 1 |
| Verdie, JC | 1 |
| Alexandre, F | 1 |
| Angelini, L | 1 |
| Benezech, J | 1 |
| Burke, D | 1 |
| Ionasescu, V | 1 |
| Stegink, L | 1 |
| Mueller, S | 1 |
| Weinstein, M | 1 |
4 reviews available for glycine and Clasp-Knife Spasticity
| Article | Year |
|---|---|
Antispasticity medications: uses and limitations of enteral therapy.
Topics: 4-Aminopyridine; Acetates; Adrenergic alpha-Agonists; Amines; Baclofen; Benzodiazepines; Cyclohexane | 2004 |
[Spasticity: therapy of increased reflexes or movement disorder?].
Topics: Baclofen; Clonidine; Combined Modality Therapy; Dantrolene; Diazepam; Glycine; Humans; Locomotion; M | 1990 |
Antispasticity drugs: mechanisms of action.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Baclofen; Benzodiazepines; Central Nervous S | 1985 |
[Functional neurosurgery of cerebral palsy].
Topics: Adolescent; Adult; Animals; Baclofen; Benzodiazepines; Brain; Brain Diseases; Cerebellar Cortex; Cer | 1985 |
1 trial available for glycine and Clasp-Knife Spasticity
| Article | Year |
|---|---|
An antispasticity effect of threonine in multiple sclerosis.
Topics: Adult; Female; Glycine; Humans; Male; Multiple Sclerosis; Muscle Spasticity; Placebos; Threonine | 1992 |
15 other studies available for glycine and Clasp-Knife Spasticity
| Article | Year |
|---|---|
Plasma Metabolomic Changes in Children with Cerebral Palsy Exposed to Botulinum Neurotoxin.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Child; Cysteine; Glycine; Humans; Injections, Intramuscula | 2022 |
Opposite, bidirectional shifts in excitation and inhibition in specific types of dorsal horn interneurons are associated with spasticity and pain post-SCI.
Topics: Action Potentials; Animals; Chronic Pain; gamma-Aminobutyric Acid; Glycine; Interneurons; Male; Musc | 2017 |
Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury.
Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Carboxylic Acids; Chloride Channels; | 2010 |
[Reduced neuronal inhibition and spasticity following spinal cord injury].
Topics: Animals; Brain-Derived Neurotrophic Factor; Chlorides; gamma-Aminobutyric Acid; Glycine; H-Reflex; H | 2011 |
Influence of aminooxyacetic acid, a gamma-aminobutyrate transaminase inhibitor, on hereditary spastic defect in the mouse.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Glycine; Mice; Muscle Spasticity; Spasm; Transaminases | 1962 |
Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Biological Clocks; Brain Stem; | 2006 |
VGLUT1 and GLYT2 labeling of sacrocaudal motoneurons in the spinal cord injured spastic rat.
Topics: Animals; Behavior, Animal; Disease Progression; Female; Glutamic Acid; Glycine; Glycine Plasma Membr | 2007 |
Glycine receptors in the retinas of normal and spastic mutant mice.
Topics: Animals; Antibodies, Monoclonal; Carrier Proteins; Fluorescent Antibody Technique; Glycine; Membrane | 1994 |
The influence of glycine and related compounds on spinal cord injury-induced spasticity.
Topics: Animals; Electromyography; Glycine; H-Reflex; Male; Muscle Spasticity; Rabbits; Spinal Cord Injuries | 1995 |
The role of glycine in spinal shock.
Topics: Amino Acids; Animals; Electromyography; Evoked Potentials; Glycine; H-Reflex; Microdialysis; Motor C | 1996 |
Amino acids in spinal dorsal horn of patients during surgery for neuropathic pain or spasticity.
Topics: Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Extracellular Space; Feasibility S | 2000 |
Neurochemical correlates of spasticity.
Topics: Animals; Aspartic Acid; Dogs; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Muscle Spasticit | 1976 |
Effects of glycine administration on canine experimental spinal spasticity and the levels of glycine, glutamate, and aspartate in the lumbar spinal cord.
Topics: Animals; Aspartic Acid; Dogs; Female; Glutamates; Glycine; Muscle Hypotonia; Muscle Spasticity; Spin | 1979 |
Drug treatment of spasticity.
Topics: Aminobutyrates; Animals; Cats; Decerebrate State; Glycine; Humans; Motor Neurons; Muscle Spasticity; | 1970 |
Amino acid abnormality in Sjögren-Larsson syndrome.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; G | 1973 |