Page last updated: 2024-10-18

glycine and Choriocarcinoma

glycine has been researched along with Choriocarcinoma in 3 studies

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research Excerpts

ExcerptRelevanceReference
"Transport of glycine in confluent monolayer cultures of JAR human placental choriocarcinoma cells was investigated."7.69Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR). ( Ganapathy, V; Leibach, FH; Liu, W, 1994)
"Functional potencies of unlabeled compounds were characterized by [14C]glycine uptake into JAR (human placental choriocarcinoma) cells and synaptosomes."3.74A novel radioligand for glycine transporter 1: characterization and use in autoradiographic and in vivo brain occupancy studies. ( Lemaire, W; Lindsley, CW; Miller, PJ; O'Brien, JA; O'Malley, SS; Raab, C; Sur, C; Wallace, MA; Williams, DL; Zeng, Z; Zhao, Z, 2008)
"Augmentation strategy in the treatment of schizophrenia with the NMDA receptor co-agonist glycine has demonstrated significant improvement in patient symptoms."3.72Effects of typical and atypical antipsychotics on human glycine transporters. ( Conn, PJ; Mallorga, PJ; Pettibone, DJ; Sur, C; Williams, JB, 2004)
"Transport of glycine in confluent monolayer cultures of JAR human placental choriocarcinoma cells was investigated."3.69Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR). ( Ganapathy, V; Leibach, FH; Liu, W, 1994)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Williams, JB1
Mallorga, PJ1
Conn, PJ1
Pettibone, DJ1
Sur, C2
Zeng, Z1
O'Brien, JA1
Lemaire, W1
O'Malley, SS1
Miller, PJ1
Zhao, Z1
Wallace, MA1
Raab, C1
Lindsley, CW1
Williams, DL1
Liu, W1
Leibach, FH1
Ganapathy, V1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070]68 participants (Actual)Interventional2007-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for glycine and Choriocarcinoma

ArticleYear
Effects of typical and atypical antipsychotics on human glycine transporters.
    Schizophrenia research, 2004, Nov-01, Volume: 71, Issue:1

    Topics: Amino Acid Transport Systems, Neutral; Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlori

2004
A novel radioligand for glycine transporter 1: characterization and use in autoradiographic and in vivo brain occupancy studies.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:3

    Topics: Animals; Autoradiography; Benzamides; Binding, Competitive; Brain; Carbon Radioisotopes; Cell Line,

2008
Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR).
    Biochimica et biophysica acta, 1994, Aug-24, Volume: 1194, Issue:1

    Topics: Alanine; Amino Acid Transport Systems, Neutral; Anions; Biological Transport; Carrier Proteins; Cati

1994