glycine has been researched along with Child Development Disorders, Pervasive in 5 studies
Child Development Disorders, Pervasive: Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Creatine deficiency syndrome (CDS) is one form of inborn error of metabolism where affected individuals have similar clinical features to individuals with ASD." | 7.76 | Is there a role for routinely screening children with autism spectrum disorder for creatine deficiency syndrome? ( Angley, MT; Gerber, JP; McKinnon, RA; Sorich, MJ; Wang, L; Young, RL, 2010) |
| " Creatine deficiency syndrome (CDS) is one form of inborn error of metabolism where affected individuals have similar clinical features to individuals with ASD." | 3.76 | Is there a role for routinely screening children with autism spectrum disorder for creatine deficiency syndrome? ( Angley, MT; Gerber, JP; McKinnon, RA; Sorich, MJ; Wang, L; Young, RL, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, L | 2 |
| Parlar, S | 2 |
| Kvist, K | 1 |
| Whiteley, P | 2 |
| Shattock, P | 2 |
| Wang, L | 3 |
| Angley, MT | 3 |
| Gerber, JP | 3 |
| Young, RL | 2 |
| Abarno, DV | 1 |
| McKinnon, RA | 2 |
| Sorich, MJ | 3 |
| Haracopos, D | 1 |
| Knivsberg, AM | 1 |
| Reichelt, KL | 1 |
| Jacobsen, J | 1 |
| Seim, A | 1 |
| Schondel, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A1 Beta Casein Free Milk (a2 Milk) for Autism and Attention-deficit Hyperactivity Disorder[NCT02911194] | 40 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| The ScanBrit Randomised Controlled Study of Gluten- and Casein-free Dietary Intervention for Children With Autism Spectrum Disorders[NCT00614198] | Phase 2 | 72 participants (Actual) | Interventional | 2006-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
ADOS (Autism Diagnostic Observation Schedule): module 1 cutoff scores (communication+social): autism=12, autism spectrum (AS)=7; module 2 cutoffs: autism=12, AS=8; module 3 cutoffs: autism=10; AS=7. GARS (Gilliam Autism Rating Scale): <80 low probability of autism, 81-90 below average, 91-110 average, >110 above average probability of autism. VABS (Vineland Adaptive Behaviour Scale): <69 (low ability), 70-84 (moderate/low), 85-115 (adequate), 116-130 (moderate/high), >130 (high). ADHD-IV: 0=no problems indicated. >11 attention & >11 hyperactivity = ADHD diagnosis. (NCT00614198)
Timeframe: Baseline - 8 months - 12 months - 24 months
| Intervention | Units on a scale (Mean) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADOS - Communication (8 months) | ADOS - Communication (24 months) | ADOS - Social (8 months) | ADOS - Social (24 months) | ADOS - Repetitive behaviours (8 months) | ADOS - Reptitive behaviours (24 months) | GARS - Social (8 months) | GARS - Social (12 months) | GARS - Social (24 months) | GARS - Communication (8 months) | GARS - Communication (12 months) | GARS - Communication (24 months) | GARS - Stereotyped behaviours (8 months) | GARS - Stereotyped behaviours (12 months) | GARS - Stereotyped behaviours (24 months) | VABS - Communication (8 months) | VABS - Communication (12 months) | VABS - Communication (24 months) | VABS - Social (8 months) | VABS - Social (12 months) | VABS - Social (24 months) | VABS - Daily Living (8 months) | VABS - Daily Living (12 months) | VABS - Daily Living (24 months) | ADHD-IV - Inattention (8 months) | ADHD-IV - Inattention (12 months) | ADHD-IV - Inattention (24 months) | ADHD-IV - Hyperactivity (8 months) | ADHD-IV - Hyperactivity (12 months) | ADHD-IV Hyperactivity (24 months) | |
| Gluten- and Casein-free Dietary Intervention | -0.16715 | -0.16176 | 0.016807 | -0.5042 | -0.14706 | -0.14216 | -1.07692 | -1.57692 | -1.88235 | -1.23077 | -1.47826 | -2 | -0.96154 | -1.46154 | -0.88235 | 0.23077 | 0.92308 | 1.27778 | 1.53846 | -4.15385 | 0.72222 | 3.03846 | 3.46154 | -0.16667 | -2.15385 | -2.19231 | -2.29412 | -2.03846 | -1.69231 | -2.58824 |
| No Gluten- and Casein-free Dietary Intervention | 0.08235 | 0.18529 | 0.02521 | 0.02521 | 0.03431 | -0.0049 | -0.06897 | -0.42308 | -1.11765 | -0.51724 | -1.46154 | -1.29412 | -0.7931 | -1.3333 | -1.70588 | 1.25 | 1.85714 | -2.05882 | 0.92857 | -3.25 | -3.29412 | -1.64286 | -2.85714 | -4.64706 | 0.31034 | -0.03704 | -3.35294 | -0.17241 | -0.92593 | -4.17647 |
1 review available for glycine and Child Development Disorders, Pervasive
| Article | Year |
|---|---|
A review of candidate urinary biomarkers for autism spectrum disorder.
Topics: Biomarkers; Child; Child Development Disorders, Pervasive; Glycine; Humans; Neopterin; Neurotransmit | 2011 |
2 trials available for glycine and Child Development Disorders, Pervasive
| Article | Year |
|---|---|
Data mining the ScanBrit study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders: behavioural and psychometric measures of dietary response.
Topics: Attention; Caseins; Child; Child Development Disorders, Pervasive; Child, Preschool; Data Mining; Di | 2014 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Topics: Aging; Attention; Caseins; Child; Child Development; Child Development Disorders, Pervasive; Child, | 2010 |
2 other studies available for glycine and Child Development Disorders, Pervasive
| Article | Year |
|---|---|
Is urinary indolyl-3-acryloylglycine a biomarker for autism with gastrointestinal symptoms?
Topics: Autistic Disorder; Biomarkers; Child; Child Development Disorders, Pervasive; Creatinine; Female; Ga | 2009 |
Is there a role for routinely screening children with autism spectrum disorder for creatine deficiency syndrome?
Topics: Biomarkers; Brain Diseases, Metabolic, Inborn; Child; Child Development Disorders, Pervasive; Chroma | 2010 |