glycine has been researched along with Child Development Deviations in 24 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autism is a heterogeneous pervasive developmental disorder with a poorly defined aetiology and pathophysiology." | 5.32 | Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. ( Anderson, R; Bull, G; Groundwater, PW; Lees, G; Lough, JW; Shattock, P; Whiteley, P, 2003) |
| "l-arginine:glycine amidinotransferase (AGAT) and its metabolites homoarginine (hArg) and creatine have been linked to stroke pathology in both human and mouse studies." | 3.96 | Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency. ( Arunachalam, P; Choe, CU; Gelderblom, M; Gerloff, C; Jensen, M; Magnus, T; Müller, C; Schwedhelm, E; Zeller, T, 2020) |
| " AGAT patients might benefit from oral GAA due to upgraded bioavailability and convenient utilization of the compound, while possible drawbacks (e." | 2.61 | Benefits and drawbacks of guanidinoacetic acid as a possible treatment to replenish cerebral creatine in AGAT deficiency. ( Ostojic, SM, 2019) |
| "Treatment with creatine monohydrate (100-800 mg/kg/day) resulted in almost complete restoration of brain creatine levels and significant improvement of myopathy." | 1.42 | Arginine:glycine amidinotransferase (AGAT) deficiency: Clinical features and long term outcomes in 16 patients diagnosed worldwide. ( Apatean, D; Battini, R; DeBrosse, S; Dessoffy, K; Dowling, MD; Edvardson, S; Eichler, F; Johnston, K; Koeller, DM; Nouioua, S; Stockler-Ipsiroglu, S; Tazir, M; Verma, A; Wierenga, AM; Wierenga, KJ; Wong, LJ; Zhang, V, 2015) |
| "The observed constellation of microcephaly, deafness, cryptorchidism, developmental delay, hypertension, and bilateral pheochromocytoma in association with a VHL mutation A451G in a patient with negative family history has not previously been described in the literature." | 1.32 | Bilateral pheochromocytomas and congenital anomalies associated with a de novo germline mutation in the von Hippel-Lindau gene. ( Assadi, F; Brackbill, EL, 2003) |
| "Autism is a heterogeneous pervasive developmental disorder with a poorly defined aetiology and pathophysiology." | 1.32 | Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. ( Anderson, R; Bull, G; Groundwater, PW; Lees, G; Lough, JW; Shattock, P; Whiteley, P, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.83) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 6 (25.00) | 24.3611 |
| 2020's | 5 (20.83) | 2.80 |
| Authors | Studies |
|---|---|
| Balestrino, M | 1 |
| Adriano, E | 1 |
| Kirby, T | 1 |
| Walters, DC | 1 |
| Brown, M | 1 |
| Jansen, E | 1 |
| Salomons, GS | 3 |
| Turgeon, C | 1 |
| Rinaldo, P | 1 |
| Arning, E | 1 |
| Ashcraft, P | 1 |
| Bottiglieri, T | 1 |
| Roullet, JB | 1 |
| Gibson, KM | 1 |
| Jensen, M | 1 |
| Müller, C | 1 |
| Schwedhelm, E | 2 |
| Arunachalam, P | 1 |
| Gelderblom, M | 1 |
| Magnus, T | 1 |
| Gerloff, C | 2 |
| Zeller, T | 1 |
| Choe, CU | 2 |
| Neu, A | 1 |
| Hornig, S | 1 |
| Sasani, A | 1 |
| Isbrandt, D | 1 |
| Tsikas, D | 1 |
| Zagefka, H | 1 |
| Huynh, HP | 1 |
| Senger, AR | 1 |
| Derington, CG | 1 |
| Colantonio, LD | 1 |
| Herrick, JS | 1 |
| Cook, J | 1 |
| King, JB | 1 |
| Rosenson, RS | 1 |
| Poudel, B | 1 |
| Monda, KL | 1 |
| Navar, AM | 1 |
| Mues, KE | 1 |
| Stevens, VW | 1 |
| Nelson, RE | 1 |
| Vanneman, ME | 1 |
| Muntner, P | 1 |
| Bress, AP | 1 |
| Ma, B | 1 |
| Ren, G | 1 |
| Xu, J | 1 |
| Yin, C | 1 |
| Shi, Y | 1 |
| Rahsepar, AA | 1 |
| Bluemke, DA | 1 |
| Habibi, M | 1 |
| Liu, K | 1 |
| Kawel-Boehm, N | 1 |
| Ambale-Venkatesh, B | 1 |
| Fernandes, VRS | 1 |
| Rosen, BD | 1 |
| Lima, JAC | 1 |
| Carr, JC | 1 |
| Freitag, TM | 1 |
| Chen-Sankey, JC | 1 |
| Duarte, DA | 1 |
| Ramsey, MW | 1 |
| Choi, K | 1 |
| Winkler-Heil, R | 1 |
| Hussain, M | 1 |
| Hofmann, W | 1 |
| Nicotera, AG | 1 |
| Dicanio, D | 1 |
| Pironti, E | 1 |
| Bonsignore, M | 1 |
| Cafeo, A | 1 |
| Efthymiou, S | 1 |
| Mondello, P | 1 |
| Salpietro, V | 1 |
| Houlden, H | 1 |
| Di Rosa, G | 1 |
| Hayes-Ryan, D | 1 |
| O'Donoghue, K | 1 |
| McCarthy, C | 1 |
| Totorika, A | 1 |
| Meaney, S | 1 |
| Pang, RD | 1 |
| Dormanesh, A | 1 |
| Hoang, Y | 1 |
| Chu, M | 1 |
| Allem, JP | 1 |
| Girón-Ortega, JA | 1 |
| Márquez-Coello, M | 1 |
| Gutiérrez-Saborido, D | 1 |
| Arizcorreta, A | 1 |
| Cuesta-Sancho, S | 1 |
| Girón-González, JA | 1 |
| Dovrat, G | 1 |
| Pevzner, S | 1 |
| Berthon, C | 1 |
| Lerner, A | 1 |
| Maimon, E | 1 |
| Vainer, R | 1 |
| Karpasas, M | 1 |
| Ben-Elyiahu, Y | 1 |
| Moisy, P | 1 |
| Bettelheim, A | 1 |
| Zilbermann, I | 1 |
| Vanden Broeck, SMP | 1 |
| Nelson, DJ | 1 |
| Collado, A | 1 |
| Falivene, L | 1 |
| Cavallo, L | 1 |
| Cordes, DB | 1 |
| Slawin, AMZ | 1 |
| Van Hecke, K | 1 |
| Nahra, F | 1 |
| Cazin, CSJ | 1 |
| Nolan, SP | 1 |
| Kranidiotis-Hisatomi, N | 1 |
| Yi, H | 1 |
| Oestreich, M | 1 |
| Kwiezinski, C | 1 |
| Weller, C | 1 |
| van Pinxteren, D | 1 |
| Brüggemann, M | 1 |
| Mertes, S | 1 |
| Stratmann, F | 1 |
| Herrmann, H | 1 |
| Treggiari, D | 1 |
| Tridello, G | 1 |
| Menin, L | 1 |
| Borruso, A | 1 |
| Pintani, E | 1 |
| Iansa, P | 1 |
| Cipolli, M | 1 |
| Melotti, P | 1 |
| Ren, L | 1 |
| Liu, L | 3 |
| Shu, X | 1 |
| Lin, W | 1 |
| Yang, P | 1 |
| Chen, J | 1 |
| Teo, KL | 1 |
| Xiao, F | 1 |
| Wang, H | 1 |
| Yao, T | 1 |
| Zhao, X | 1 |
| Yang, X | 1 |
| Yu, DYW | 1 |
| Rogach, AL | 1 |
| Bordet, A | 1 |
| Leitner, W | 1 |
| Gao, S | 1 |
| Xia, F | 1 |
| Li, B | 2 |
| Abdul Razak, IB | 1 |
| Liu, Y | 1 |
| Lu, K | 1 |
| Brown, DE | 1 |
| Wang, R | 1 |
| Cheng, Y | 1 |
| Ni, S | 1 |
| Qu, H | 1 |
| Xing, H | 1 |
| Xu, Z | 1 |
| Zhu, X | 1 |
| Yuan, M | 1 |
| Wang, L | 1 |
| Yu, J | 1 |
| Li, Y | 1 |
| Yang, L | 1 |
| Liu, H | 1 |
| Cao, L | 1 |
| Zhang, S | 1 |
| Zhao, D | 1 |
| Yan, T | 1 |
| Yang, G | 1 |
| Lin, Z | 1 |
| Luo, M | 1 |
| Ye, N | 1 |
| Lee, SW | 1 |
| Carnicelli, J | 1 |
| Getya, D | 1 |
| Gitsov, I | 1 |
| Phillips, KS | 1 |
| Ren, D | 1 |
| Grützmacher, PG | 1 |
| Suarez, S | 1 |
| Tolosa, A | 1 |
| Gachot, C | 1 |
| Song, G | 1 |
| Wang, B | 1 |
| Presser, V | 1 |
| Mücklich, F | 1 |
| Anasori, B | 1 |
| Rosenkranz, A | 1 |
| Demireva, M | 1 |
| Armentrout, PB | 1 |
| Feng, D | 1 |
| Cao, K | 1 |
| He, ZZ | 1 |
| Knibbs, LD | 1 |
| Jalaludin, B | 1 |
| Leskinen, A | 1 |
| Roponen, M | 1 |
| Komppula, M | 1 |
| Jalava, P | 1 |
| Guo, PY | 1 |
| Xu, SL | 1 |
| Yang, BY | 1 |
| Hu, L | 1 |
| Zeng, XW | 1 |
| Chen, G | 1 |
| Yu, HY | 1 |
| Lin, L | 1 |
| Dong, G | 1 |
| Machulkin, AE | 1 |
| Shafikov, RR | 1 |
| Uspenskaya, AA | 1 |
| Petrov, SA | 1 |
| Ber, AP | 1 |
| Skvortsov, DA | 1 |
| Nimenko, EA | 1 |
| Zyk, NU | 1 |
| Smirnova, GB | 1 |
| Pokrovsky, VS | 1 |
| Abakumov, MA | 1 |
| Saltykova, IV | 1 |
| Akhmirov, RT | 1 |
| Garanina, AS | 1 |
| Polshakov, VI | 1 |
| Saveliev, OY | 1 |
| Ivanenkov, YA | 1 |
| Aladinskaya, AV | 1 |
| Finko, AV | 1 |
| Yamansarov, EU | 1 |
| Krasnovskaya, OO | 1 |
| Erofeev, AS | 1 |
| Gorelkin, PV | 1 |
| Dontsova, OA | 1 |
| Beloglazkina, EK | 1 |
| Zyk, NV | 1 |
| Khazanova, ES | 1 |
| Majouga, AG | 1 |
| Zheng, YK | 1 |
| Su, BJ | 1 |
| Wang, YQ | 1 |
| Wang, HS | 1 |
| Liao, HB | 1 |
| Liang, D | 1 |
| Shataer, D | 1 |
| Li, J | 1 |
| Duan, XM | 1 |
| Xin, XL | 1 |
| Aisa, HA | 1 |
| Allu, SR | 1 |
| Ravotto, L | 1 |
| Troxler, T | 1 |
| Vinogradov, SA | 1 |
| Cheruku, RR | 1 |
| Tracy, EC | 1 |
| Tabaczynski, W | 1 |
| Missert, JR | 1 |
| Baumann, H | 1 |
| Pandey, RK | 1 |
| Rohde, JM | 1 |
| Karavadhi, S | 1 |
| Pragani, R | 1 |
| Fang, Y | 1 |
| Zhang, W | 1 |
| McIver, A | 1 |
| Zheng, H | 1 |
| Liu, Q | 1 |
| Davis, MI | 1 |
| Urban, DJ | 1 |
| Lee, TD | 1 |
| Cheff, DM | 1 |
| Hollingshead, M | 1 |
| Henderson, MJ | 1 |
| Martinez, NJ | 1 |
| Brimacombe, KR | 1 |
| Yasgar, A | 1 |
| Zhao, W | 1 |
| Klumpp-Thomas, C | 1 |
| Michael, S | 1 |
| Covey, J | 1 |
| Moore, WJ | 1 |
| Stott, GM | 1 |
| Li, Z | 1 |
| Simeonov, A | 1 |
| Jadhav, A | 1 |
| Frye, S | 1 |
| Hall, MD | 1 |
| Shen, M | 1 |
| Wang, X | 1 |
| Patnaik, S | 1 |
| Boxer, MB | 1 |
| Zhang, H | 2 |
| Cheng, C | 1 |
| Huang, B | 1 |
| Chen, R | 1 |
| Huang, Y | 1 |
| Chen, H | 1 |
| Pei, W | 1 |
| Katahara, S | 1 |
| Sugiyama, Y | 1 |
| Yamane, M | 1 |
| Komiya, Y | 1 |
| Sato, T | 1 |
| Chida, N | 1 |
| Ostojic, SM | 1 |
| Amin, JB | 1 |
| Leng, X | 1 |
| Gochman, A | 1 |
| Zhou, HX | 1 |
| Wollmuth, LP | 1 |
| Nouioua, S | 2 |
| Cheillan, D | 1 |
| Zaouidi, S | 1 |
| Amedjout, N | 1 |
| Kessaci, F | 1 |
| Boulahdour, N | 1 |
| Hamadouche, T | 1 |
| Tazir, M | 2 |
| Stockler-Ipsiroglu, S | 1 |
| Apatean, D | 1 |
| Battini, R | 1 |
| DeBrosse, S | 1 |
| Dessoffy, K | 1 |
| Edvardson, S | 1 |
| Eichler, F | 1 |
| Johnston, K | 2 |
| Koeller, DM | 1 |
| Verma, A | 1 |
| Dowling, MD | 1 |
| Wierenga, KJ | 1 |
| Wierenga, AM | 1 |
| Zhang, V | 1 |
| Wong, LJ | 1 |
| Koene, S | 1 |
| Kluijtmans, LAJ | 1 |
| Wevers, R | 1 |
| Mock, D | 1 |
| Pasch, M | 1 |
| Morava, E | 1 |
| Barger, AV | 1 |
| Campeau, NG | 1 |
| Port, JD | 1 |
| Renaud, DL | 1 |
| Furuse, T | 1 |
| Yamada, I | 1 |
| Kushida, T | 1 |
| Masuya, H | 1 |
| Miura, I | 1 |
| Kaneda, H | 1 |
| Kobayashi, K | 1 |
| Wada, Y | 1 |
| Yuasa, S | 1 |
| Wakana, S | 1 |
| Ndika, JD | 1 |
| Barkovich, JA | 1 |
| Wirt, MD | 1 |
| O'Neill, P | 1 |
| Betsalel, OT | 1 |
| Jakobs, C | 1 |
| Assadi, F | 1 |
| Brackbill, EL | 1 |
| ZUKOWSKI, T | 1 |
| Bull, G | 1 |
| Shattock, P | 1 |
| Whiteley, P | 1 |
| Anderson, R | 1 |
| Groundwater, PW | 1 |
| Lough, JW | 1 |
| Lees, G | 1 |
| Chang, YT | 1 |
| Sharma, R | 1 |
| Marsh, JL | 1 |
| McPherson, JD | 1 |
| Bedell, JA | 1 |
| Knust, A | 1 |
| Bräutigam, C | 1 |
| Hoffmann, GF | 1 |
| Hyland, K | 1 |
| Braissant, O | 1 |
| Henry, H | 1 |
| Anselm, IA | 1 |
| Coulter, DL | 1 |
| Darras, BT | 1 |
| Redford-Ellis, M | 1 |
| Gibbs, AC | 1 |
| Haider, SA | 1 |
| Holzel, A | 1 |
| Frazier, DM | 1 |
| Summer, GK | 1 |
| Chamberlin, HR | 1 |
| Zeman, J | 1 |
| Kozich, V | 1 |
| Stastná, S | 1 |
| Hyánek, J | 1 |
| Hoza, J | 1 |
| Rajecký, J | 1 |
| Verner, P | 1 |
| Pehal, F | 1 |
| Singer, HS | 1 |
| Valle, D | 1 |
| Hayasaka, K | 1 |
| Tada, K | 1 |
| Levy, HL | 1 |
| Erickson, AM | 1 |
| Lott, IT | 1 |
| Kurtz, DJ | 1 |
2 reviews available for glycine and Child Development Deviations
| Article | Year |
|---|---|
Benefits and drawbacks of guanidinoacetic acid as a possible treatment to replenish cerebral creatine in AGAT deficiency.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Clinical Trials as Topic; Creatine; Devel | 2019 |
AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: a review.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Creatine; Developmental D | 2008 |
22 other studies available for glycine and Child Development Deviations
| Article | Year |
|---|---|
Presence of guanidinoacetate may compensate creatine absence and account for less statin-induced muscle damage in GAMT-deficient compared to AGAT-deficient mice.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine; Developmental Disabili | 2020 |
Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Brain; Carnitine; Creatine; Creatinine; De | 2020 |
Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Arginine; Brain; Creatine; Devel | 2020 |
Creatine, guanidinoacetate and homoarginine in statin-induced myopathy.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Creatine; Developmental Disabili | 2020 |
Topics: Adult; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Animals; Anti-Bacterial Agents; Anti- | 2021 |
A conserved glycine harboring disease-associated mutations permits NMDA receptor slow deactivation and high Ca
Topics: Animals; Brain Diseases; Calcium; Cell Membrane Permeability; Child; Child, Preschool; Developmental | 2018 |
Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency.
Topics: Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Brain; Child; Creatine; Developmental Dis | 2013 |
Arginine:glycine amidinotransferase (AGAT) deficiency: Clinical features and long term outcomes in 16 patients diagnosed worldwide.
Topics: Adolescent; Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Crea | 2015 |
Biotin-sensitive 3-methylcrotonylglycinuria in a patient with severe growth delay, ectodermal abnormalities, neonatal progeroid appearance, and developmental delay.
Topics: Abnormalities, Multiple; Aging, Premature; Biotin; Child, Preschool; Developmental Disabilities; Ect | 2008 |
MRS is the test of choice for detecting and monitoring disorders of creatine metabolism.
Topics: Brain; Brain Chemistry; Creatine; Developmental Disabilities; Glycine; Humans; Infant; Magnetic Reso | 2009 |
Behavioral and neuromorphological characterization of a novel Tuba1 mutant mouse.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Attention; Behavior, Animal; Bromode | 2012 |
Developmental progress and creatine restoration upon long-term creatine supplementation of a patient with arginine:glycine amidinotransferase deficiency.
Topics: Amidinotransferases; Brain; Child; Creatine; Developmental Disabilities; Dietary Supplements; Female | 2012 |
Bilateral pheochromocytomas and congenital anomalies associated with a de novo germline mutation in the von Hippel-Lindau gene.
Topics: Adrenal Gland Neoplasms; Amino Acid Substitution; Child; Cryptorchidism; Developmental Disabilities; | 2003 |
[Action of glycocoll in strong doses in the delayed development of muscular strength in infants].
Topics: Child; Developmental Disabilities; Fabaceae; Glycine; Humans; Muscle Strength | 1959 |
Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders.
Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Biological Assay; Child; Child, Preschool; Chroma | 2003 |
Levodopa-responsive aromatic L-amino acid decarboxylase deficiency.
Topics: Adolescent; Adult; Alanine; Antiparkinson Agents; Aromatic-L-Amino-Acid Decarboxylases; Binding Site | 2004 |
Cardiac manifestations in a child with a novel mutation in creatine transporter gene SLC6A8.
Topics: Base Sequence; Brain Chemistry; Child; Child Behavior Disorders; Creatine; Developmental Disabilitie | 2008 |
Aminoaciduria in handicapped children: a study using ion-exchange chromatography as a screening test.
Topics: Amino Acids; Child; Child, Preschool; Chromatography, Ion Exchange; Cystathionine; Developmental Dis | 1981 |
Hyperglycinuria and hyperglycinemia in two siblings with mild developmental delays.
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Developmental Disabilities; Electrophoresis; | 1978 |
[Non-ketotic hyperglycinemia].
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Developmental Disabilities; Glycine; Humans; | 1990 |
Nonketotic hyperglycinemia: studies in an atypical variant.
Topics: Adult; Developmental Disabilities; Glycine; Humans; Intellectual Disability; Ketosis; Male; Metaboli | 1989 |
Isovaleric acidemia: results of family study and dietary treatment.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Developmental Disabiliti | 1973 |