Page last updated: 2024-10-18

glycine and Celiac Sprue

glycine has been researched along with Celiac Sprue in 23 studies

Research Excerpts

ExcerptRelevanceReference
"Using a marker perfusing technique, the jejunal absorption rates of glycine and phenylalanine from test solutions containing either the free amino acids or glycyl-phenylalanine (30 mM each) were studied in five children with active celiac disease and in three controls."7.66Absorption of free and peptide-linked glycine and phenylalanine in children with active celiac disease. ( Fahr, K; Lutz, P; Nützenadel, W, 1981)
" Altered energy metabolism and lower cytoprotective activity (histidine, glycine, arginine) indicated vulnerability to develop intestinal inflammation in PCeD over time."4.12NMR based metabolic profiling of patients with potential celiac disease elucidating early biochemical changes of gluten-sensitivity: A pilot study. ( Das, P; Dattagupta, S; Jagannathan, NR; Makharia, GK; Sharma, U; Upadhyay, D, 2022)
"Using a marker perfusing technique, the jejunal absorption rates of glycine and phenylalanine from test solutions containing either the free amino acids or glycyl-phenylalanine (30 mM each) were studied in five children with active celiac disease and in three controls."3.66Absorption of free and peptide-linked glycine and phenylalanine in children with active celiac disease. ( Fahr, K; Lutz, P; Nützenadel, W, 1981)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199020 (86.96)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.35)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Upadhyay, D1
Das, P1
Dattagupta, S1
Makharia, GK1
Jagannathan, NR1
Sharma, U1
Mumolo, MG1
Rettura, F1
Melissari, S1
Costa, F1
Ricchiuti, A1
Ceccarelli, L1
de Bortoli, N1
Marchi, S1
Bellini, M1
Mazza, GA1
Marrazzo, S1
Gangemi, P1
Battaglia, E1
Giancotti, L1
Miniero, R1
BUTTERWORTH, CE2
SANTINI, R2
PEREZ-SANTIAGO, E1
SOLER, J1
PEREZSANTIAGO, E1
Nützenadel, W1
Fahr, K1
Lutz, P1
Bosseckert, H1
Westergaard, H1
Garbutt, JT1
Heaton, KW2
Lack, L1
Tyor, MP1
Adibi, SA1
Fogel, MR1
Agrawal, RM1
Papp, JP1
Campbell, CB1
Cowen, AE1
Harper, J1
Rubino, A1
Vetrella, M1
Pierro, M1
Rey, J1
Jos, J1
Auricchio, S1
Low-Beer, TS1
Pomare, EW1
Read, AE1
Silk, DB1
Kumar, PJ1
Perrett, D1
Clark, ML1
Dawson, AM1
Sherr, HP1
Sasaki, Y1
Newman, A1
Banwell, JG2
Wagner, HN1
Hendrix, TR1
Tarlow, MJ2
Seakins, JW2
Lloyd, JK2
Matthews, DM3
Cheng, B2
Thomas, AJ2
Nair, PP1
Gorbach, SL1
Lilis, C1
Alcaraz, A1
Bruusgaard, A1
Thaysen, EH1
Kapadia, CR1
Radhakrishnan, AN1
Mathan, VI1
Baker, SJ1
Craft, IL1
Geddes, D1
Hyde, CW1
Wise, IJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acute Glycine Pharmacodynamic Study[NCT01610011]21 participants (Actual)Interventional2010-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Brain Glycine Increments After Oral Glycine Administration Measured With MRS as Glycine/Total Creatine, Normalized to the Glycine Dose Administered (g/kg).

Brain and plasma glycine levels are measured with proton magnetic resonance spectroscopy at 4T and analytically, respectively. Because glycine doses were limited to 30 g to avoid nausea and vomiting, some subjects with higher weights were administered lower doses per body weight of glycine (g/kg). Therefore, we corrected MRS data by the actual glycine dose administered (g/kg) to account for dosing differences. (NCT01610011)
Timeframe: For up to 2 hours

InterventionPercent brain glycine/creatine increase (Mean)
Glycine Administration Controls393
Glycine Administration GLDC Mutation Subjects677

Reviews

2 reviews available for glycine and Celiac Sprue

ArticleYear
Is Gluten the Only Culprit for Non-Celiac Gluten/Wheat Sensitivity?
    Nutrients, 2020, Dec-10, Volume: 12, Issue:12

    Topics: Amylases; Celiac Disease; Diet; Diet, Carbohydrate-Restricted; Diet, Gluten-Free; Disaccharides; Fer

2020
Bile salts in health and disease.
    Michigan medicine, 1972, Volume: 71, Issue:30

    Topics: Bile Acids and Salts; Biliary Tract Diseases; Blind Loop Syndrome; Celiac Disease; Chenodeoxycholic

1972

Other Studies

21 other studies available for glycine and Celiac Sprue

ArticleYear
NMR based metabolic profiling of patients with potential celiac disease elucidating early biochemical changes of gluten-sensitivity: A pilot study.
    Clinica chimica acta; international journal of clinical chemistry, 2022, Jun-01, Volume: 531

    Topics: Arginine; Celiac Disease; Glutens; Glycine; Histidine; Humans; Inflammation; Magnetic Resonance Spec

2022
Oral iron absorption test with ferrous bisglycinate chelate in children with celiac disease.
    Minerva pediatrica, 2019, Volume: 71, Issue:2

    Topics: Administration, Oral; Adolescent; Anemia, Iron-Deficiency; Celiac Disease; Child; Child, Preschool;

2019
The absorption of glycine and its conversion to serine in patients with sprue.
    The Journal of clinical investigation, 1958, Volume: 37, Issue:1

    Topics: Celiac Disease; Glycine; Humans; Serine

1958
Certain aspects of glycine and histidine metabolism in patients with sprue.
    Blood, 1960, Volume: 15

    Topics: Celiac Disease; Glycine; Histidine; Humans

1960
Absorption of free and peptide-linked glycine and phenylalanine in children with active celiac disease.
    Pediatric research, 1981, Volume: 15, Issue:4 Pt 1

    Topics: Adolescent; Amino Acids; Celiac Disease; Child; Dipeptides; Glycine; Humans; Intestinal Absorption;

1981
[Gastroenterologic diseases and their relationship to the urogenital system].
    Zeitschrift fur Urologie und Nephrologie, 1978, Volume: 71, Issue:9

    Topics: Amyloidosis; Bile Acids and Salts; Celiac Disease; Cholelithiasis; Cholestyramine Resin; Colitis, Ul

1978
Duodenal bile acid concentrations in fat malabsorption syndromes.
    Scandinavian journal of gastroenterology, 1977, Volume: 12, Issue:1

    Topics: Adult; Bile Acids and Salts; Biliary Tract Diseases; Celiac Disease; Duodenum; Female; Food; Glycine

1977
Increased ratio of glycine- to taurine-conjugated bile salts in patients with ileal disorders.
    Gastroenterology, 1969, Volume: 56, Issue:4

    Topics: Adolescent; Adult; Aged; Bile Acids and Salts; Carbon Isotopes; Celiac Disease; Colostomy; Crohn Dis

1969
Comparison of free amino acid and dipeptide absorption in the jejunum of sprue patients.
    Gastroenterology, 1974, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acids; Celiac Disease; Dipeptides; Female; Glycine; Glycylglycine; Hu

1974
Duodenal bacterial flora and bile salt patterns in patients with gastrointestinal disease.
    Australian and New Zealand journal of medicine, 1973, Volume: 3, Issue:4

    Topics: Adult; Aged; Bacteria; Bile Acids and Salts; Celiac Disease; Child; Chromatography, Thin Layer; Duod

1973
Intestinal glutaminyl-proline dipeptidase activity in children with treated coeliac disease.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1972, Volume: 17, Issue:10

    Topics: Celiac Disease; Child, Preschool; Diet Therapy; Dipeptidases; Female; Glutamates; Glycine; Glycoside

1972
The effect of coeliac disease upon bile salts.
    Gut, 1973, Volume: 14, Issue:3

    Topics: Adult; Bile Acids and Salts; Carbon Isotopes; Celiac Disease; Chenodeoxycholic Acid; Chromatography,

1973
Amino acid, dipeptide, and protein absorption in human beings.
    Nutrition reviews, 1973, Volume: 31, Issue:9

    Topics: Adult; Alanine; Amino Acids; Antibody Formation; Arginine; Biological Transport; Celiac Disease; Chi

1973
Amino acid and peptide absorption in patients with coeliac disease and dermatitis herpetiformis.
    Gut, 1974, Volume: 15, Issue:1

    Topics: Adult; Aged; Alanine; Amino Acids; Celiac Disease; Dermatitis Herpetiformis; Dipeptides; Glycine; Hu

1974
Detection of bacterial deconjugation of bile salts by a convenient breath-analysis technic.
    The New England journal of medicine, 1971, Sep-16, Volume: 285, Issue:12

    Topics: Adult; Aged; Air; Bacteria; Bile Acids and Salts; Carbon Dioxide; Carbon Isotopes; Celiac Disease; C

1971
Absorption of amino acids and peptides in a child with a variant of Hartnup disease and coexistent coeliac disease.
    Archives of disease in childhood, 1972, Volume: 47, Issue:255

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Biopsy; Celiac Disease; Dipeptides; Glycine; Hart

1972
Tropical sprue and malnutrition in West Bengal. 3. Biochemical characteristics of bile salts in the small intestine.
    The American journal of clinical nutrition, 1970, Volume: 23, Issue:12

    Topics: Adult; Bile Acids and Salts; Celiac Disease; Glycine; Humans; Intestine, Small; Liver; Male; Middle

1970
Intestinal absorption and biopsy transport of peptides and amino acids in Hartnup disease.
    Clinical science, 1970, Volume: 39, Issue:6

    Topics: Amino Acids; Biological Transport; Biopsy; Body Fluids; Celiac Disease; Dipeptides; Glycine; Hartnup

1970
Increased ratio of glycine-taurine conjugated bile acids in the early diagnosis of terminal ileopathy. Preliminary report.
    Acta medica Scandinavica, 1970, Volume: 188, Issue:6

    Topics: Adult; Bile Acids and Salts; Celiac Disease; Crohn Disease; Diarrhea; Duodenum; Female; Glycine; Hum

1970
A study of the ratios of bile salt conjugates of glycine to taurine in the jejunum and ileum in patients with tropical sprue.
    Scandinavian journal of gastroenterology, 1971, Volume: 6, Issue:4

    Topics: Bile Acids and Salts; Biological Transport; Celiac Disease; Feces; Glycine; Humans; Ileum; Jejunum;

1971
Absorption and malabsorption of glycine and glycine peptides in man.
    Gut, 1968, Volume: 9, Issue:4

    Topics: Adult; Aged; Celiac Disease; Digestion; Female; Gastrectomy; Glycine; Humans; Intestinal Absorption;

1968