glycine has been researched along with Cardiomegaly in 20 studies
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pre-treatment with glycine significantly attenuated murine cardiac hypertrophy induced by transverse aortic constriction or by administration of angiotensin II (Ang II)." | 5.46 | Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. ( Bai, H; Ben, J; Chen, Q; Fang, R; Li, J; Li, K; Li, X; Lu, Y; Wang, Z; Yang, Q; Zhang, H; Zhang, J; Zhu, X, 2017) |
| " In an angiotensin II (Ang II) hypertension model, FG-4592 abolished hypertensive responses; prevented vascular thickening, cardiac hypertrophy, and kidney injury; downregulated AGTR1 expression; and enhanced AGTR2, endothelial NO synthase (eNOS), and HIF1α protein levels in the aortas of mice." | 4.02 | Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS. ( Huang, S; Jia, Z; Niu, Y; Shi, W; Wang, S; Yu, J; Zhang, A; Zhang, Y; Zhou, W, 2021) |
| "In mice with cardiac hypertrophy, KB-R7785 inhibited the shedding of HB-EGF and attenuated hypertrophic changes." | 2.42 | [Membrane-anchored heparin-binding EGF-like growth factor processing by ADAM12 in cardiac hypertrophy]. ( Higashiyama, S, 2003) |
| "Pre-treatment with glycine significantly attenuated murine cardiac hypertrophy induced by transverse aortic constriction or by administration of angiotensin II (Ang II)." | 1.46 | Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor. ( Bai, H; Ben, J; Chen, Q; Fang, R; Li, J; Li, K; Li, X; Lu, Y; Wang, Z; Yang, Q; Zhang, H; Zhang, J; Zhu, X, 2017) |
| "Rats were cold acclimated to induce cardiac hypertrophy and increase cardiac LPL." | 1.38 | Cardiac lipoprotein lipase activity in the hypertrophied heart may be regulated by fatty acid flux. ( Caldwell, GM; Hauton, D, 2012) |
| "In mice with cardiac hypertrophy, KB-R7785 inhibited the shedding of HB-EGF and attenuated hypertrophic changes." | 1.31 | Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. ( Asakura, M; Asanuma, H; Beppu, S; Higashiyama, S; Hori, M; Ishiguro, H; Ishikura, F; Kitakaze, M; Liao, Y; Matsumura, Y; Node, K; Ohmoto, H; Sanada, S; Tada, M; Takashima, S; Takeda, H; Yoshinaka, T; Yoshino, K, 2002) |
| " Chronic administration of oxfenicine to dogs for 1 year produced dose-related, nonpathological increases in relative heart weight (up to 85% at 750 mg/kg per day)." | 1.27 | Coronary hyperemia and cardiac hypertrophy following inhibition of fatty acid oxidation. Evidence of a regulatory role for cytosolic phosphorylation potential. ( Faccini, JM; Greaves, P; Higgins, AJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (65.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, J | 1 |
| Wang, S | 1 |
| Shi, W | 1 |
| Zhou, W | 1 |
| Niu, Y | 1 |
| Huang, S | 1 |
| Zhang, Y | 1 |
| Zhang, A | 1 |
| Jia, Z | 1 |
| Lu, Y | 1 |
| Zhu, X | 1 |
| Li, J | 1 |
| Fang, R | 1 |
| Wang, Z | 1 |
| Zhang, J | 1 |
| Li, K | 1 |
| Li, X | 1 |
| Bai, H | 1 |
| Yang, Q | 1 |
| Ben, J | 1 |
| Zhang, H | 1 |
| Chen, Q | 1 |
| Hauton, D | 1 |
| Caldwell, GM | 1 |
| Higashiyama, S | 2 |
| Van Coster, R | 1 |
| Seneca, S | 1 |
| Smet, J | 1 |
| Van Hecke, R | 1 |
| Gerlo, E | 1 |
| Devreese, B | 1 |
| Van Beeumen, J | 1 |
| Leroy, JG | 1 |
| De Meirleir, L | 1 |
| Lissens, W | 1 |
| GUDBJARNASON, S | 2 |
| TELERMAN, M | 2 |
| BING, RJ | 2 |
| CHIBA, C | 1 |
| WOLF, PL | 1 |
| McKenzie, JC | 1 |
| Klein, RM | 1 |
| Greaves, P | 2 |
| Martin, J | 1 |
| Michel, MC | 1 |
| Mompon, P | 1 |
| Bing, W | 1 |
| Knott, A | 1 |
| Redwood, C | 1 |
| Esposito, G | 1 |
| Purcell, I | 1 |
| Watkins, H | 1 |
| Marston, S | 1 |
| Asakura, M | 1 |
| Kitakaze, M | 1 |
| Takashima, S | 1 |
| Liao, Y | 1 |
| Ishikura, F | 1 |
| Yoshinaka, T | 1 |
| Ohmoto, H | 1 |
| Node, K | 1 |
| Yoshino, K | 1 |
| Ishiguro, H | 1 |
| Asanuma, H | 1 |
| Sanada, S | 1 |
| Matsumura, Y | 1 |
| Takeda, H | 1 |
| Beppu, S | 1 |
| Tada, M | 1 |
| Hori, M | 1 |
| Köbel, F | 1 |
| Dorazilová, V | 1 |
| Kümmel, L | 1 |
| Huxtable, R | 1 |
| Chubb, J | 1 |
| Higgins, AJ | 1 |
| Faccini, JM | 1 |
| Pogosova, AV | 1 |
| Kaku, I | 1 |
| Stanton, HC | 1 |
| Bowman, Z | 1 |
| Cooper, CM | 1 |
| Zimmer, HG | 3 |
| Trendelenburg, C | 1 |
| Gerlach, E | 3 |
| Steinkopff, G | 1 |
2 reviews available for glycine and Cardiomegaly
| Article | Year |
|---|---|
[Membrane-anchored heparin-binding EGF-like growth factor processing by ADAM12 in cardiac hypertrophy].
Topics: ADAM Proteins; ADAM12 Protein; Animals; Cardiomegaly; Depression, Chemical; Epidermal Growth Factor; | 2003 |
[Synthesis of proteins and nucleotides in the hypertrophying myocardium].
Topics: Adenine Nucleotides; Animals; Aorta; Carbon Isotopes; Cardiomegaly; Glycine; Ligation; Muscle Protei | 1972 |
18 other studies available for glycine and Cardiomegaly
| Article | Year |
|---|---|
Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Cells, Cultured; Electrolytes; Endothe | 2021 |
Glycine prevents pressure overload induced cardiac hypertrophy mediated by glycine receptor.
Topics: Angiotensin II; Animals; Cardiomegaly; Coculture Techniques; Glycine; Heart; Male; MAP Kinase Signal | 2017 |
Cardiac lipoprotein lipase activity in the hypertrophied heart may be regulated by fatty acid flux.
Topics: Angiopoietin-Like Protein 4; Angiopoietins; Animals; Biological Transport; Cardiomegaly; Cardiotonic | 2012 |
Homozygous Gly555Glu mutation in the nuclear-encoded 70 kDa flavoprotein gene causes instability of the respiratory chain complex II.
Topics: Amino Acids; Cardiomegaly; Cell Nucleus; Electron Transport; Electrophoresis, Polyacrylamide Gel; Fe | 2003 |
PROTEIN METABOLISM IN CARDIAC HYPERTROPHY AND HEART FAILURE.
Topics: Animals; Aortic Valve Stenosis; Carbon Isotopes; Cardiomegaly; Glycine; Heart Failure; Myocardium; P | 1964 |
MYOCARDIAL PROTEIN SYNTHESIS IN CARDIAC HYPERTROPHY.
Topics: Animals; Carbon Isotopes; Cardiomegaly; Glycine; Heart Failure; Muscle Proteins; Myocardium; Protein | 1964 |
Protein synthesis in the rat pulmonary trunk during the early development of hypoxia-induced pulmonary hypertension.
Topics: Animals; Cardiomegaly; Collagen; Glycine; Hematocrit; Hydroxyproline; Hypertension, Pulmonary; Hypox | 1983 |
Cardiac hypertrophy in the dog and rat induced by oxfenicine, an agent which modifies muscle metabolism.
Topics: Animals; Body Weight; Cardiomegaly; Dogs; Female; Glycine; Male; Myocardium; Rats; Rats, Inbred Stra | 1984 |
Effect of hypertrophic cardiomyopathy mutations in human cardiac muscle alpha -tropomyosin (Asp175Asn and Glu180Gly) on the regulatory properties of human cardiac troponin determined by in vitro motility assay.
Topics: Animals; Asparagine; Aspartic Acid; Calcium; Cardiomegaly; Cardiomyopathies; Cell Movement; Dose-Res | 2000 |
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy.
Topics: ADAM Proteins; ADAM12 Protein; Angiotensin II; Animals; Aorta, Thoracic; Cardiomegaly; Disease Model | 2002 |
Human heart aneurysm: biochemical and morphological characteristics.
Topics: Cardiomegaly; Endoplasmic Reticulum; Glucose; Glycine; Heart Aneurysm; Humans; Myocardium | 1975 |
Taurine and isoproterenol toxicity.
Topics: Animals; Cardiomegaly; Glycine; Isoproterenol; Male; Myocardium; Organ Size; Rats; Serine; Taurine; | 1976 |
Coronary hyperemia and cardiac hypertrophy following inhibition of fatty acid oxidation. Evidence of a regulatory role for cytosolic phosphorylation potential.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Creatine | 1985 |
[Biosynthesis of proteins of the subcellular structure of heart muscle in prolonged compensatory hypertrophy].
Topics: Animals; Aortic Valve Stenosis; Blood Proteins; Carbon Isotopes; Cardiomegaly; Cysteine; Glycine; Me | 1968 |
Study of the myocardial nucleic acids and proteins metabolism in experimentally induced cardiac hypertrophy and heart failure.
Topics: Animals; Body Weight; Carbon Isotopes; Cardiomegaly; Cell Nucleus; Cytoplasm; DNA; Female; Glycine; | 1968 |
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoprotereno | 1970 |
Acceleration of adenine nucleotide synthesis de novo during development of cardiac hypertrophy.
Topics: Adenine Nucleotides; Animals; Aorta, Abdominal; Carbon Isotopes; Cardiomegaly; Constriction; Female; | 1972 |
Changes of protein synthesis in the hypertrophying rat heart.
Topics: Adenosine Triphosphate; Animals; Body Weight; Carbon Isotopes; Cardiomegaly; Female; Glycine; Leucin | 1972 |