Page last updated: 2024-10-18

glycine and Cachexia

glycine has been researched along with Cachexia in 8 studies

Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.

Research Excerpts

ExcerptRelevanceReference
"Glycine protects skeletal muscle from cancer-induced wasting and loss of function, reduces the oxidative and inflammatory burden, and reduces the expression of genes associated with muscle protein breakdown in cancer cachexia."7.80Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia. ( Chee, A; Ham, DJ; Koopman, R; Lynch, GS; Murphy, KT, 2014)
"Glycine protects skeletal muscle from cancer-induced wasting and loss of function, reduces the oxidative and inflammatory burden, and reduces the expression of genes associated with muscle protein breakdown in cancer cachexia."3.80Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia. ( Chee, A; Ham, DJ; Koopman, R; Lynch, GS; Murphy, KT, 2014)
" To address this problem, we have measured the synthetic rate of fibrinogen (perhaps the major acute phase protein) and plasma amino acid profiles in a group of patients with adenocarcinoma of the pancreas and an ongoing inflammatory response (serum C-reactive protein >10 mg/L in the absence of any other obvious infective or inflammatory cause)."3.70Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response. ( Falconer, JS; Fearon, KC; McMillan, DC; Preston, T; Shenkin, A; Slater, C, 1998)
" Cumulative nitrogen retention was positive for both dosage groups (low dose, 15."2.67Anabolic effects of recombinant insulin-like growth factor-I in cachectic patients with the acquired immunodeficiency syndrome. ( Butterfield, GE; Harrison, D; Hoffman, AR; Lieberman, SA, 1994)
"Cancer cachexia is a complex metabolic disorder accounting for ~20% of cancer-related deaths, yet its metabolic landscape remains unexplored."1.91Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia. ( Aoki, M; Fujishita, T; Kajino-Sakamoto, R; Kojima, Y; Matsuo, K; Mishiro-Sato, E; Muro, K; Narita, Y; Nozawa, K; Ogata, T; Oze, I; Satoh, K; Soga, T; Taketo, MM, 2023)
"The mechanisms underlying cancer cachexia - the proximate cause of at least 20% of cancer-related deaths - have until recently remained rather obscure."1.51Nutraceutical targeting of TLR4 signaling has potential for prevention of cancer cachexia. ( Iloki-Assanga, S; Lujany, LML; McCarty, MF, 2019)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Kojima, Y1
Mishiro-Sato, E1
Fujishita, T1
Satoh, K1
Kajino-Sakamoto, R1
Oze, I1
Nozawa, K1
Narita, Y1
Ogata, T1
Matsuo, K1
Muro, K1
Taketo, MM1
Soga, T1
Aoki, M1
McCarty, MF1
Iloki-Assanga, S1
Lujany, LML1
Ham, DJ1
Murphy, KT1
Chee, A1
Lynch, GS1
Koopman, R1
Muqaku, B1
Eisinger, M1
Meier, SM1
Tahir, A1
Pukrop, T1
Haferkamp, S1
Slany, A1
Reichle, A1
Gerner, C1
Le Bricon, T1
Cynober, L1
Field, CJ1
Baracos, VE1
Lieberman, SA1
Butterfield, GE1
Harrison, D1
Hoffman, AR1
Kinscherf, R1
Hack, V1
Fischbach, T1
Friedmann, B1
Weiss, C1
Edler, L1
Bärtsch, P1
Dröge, W1
Preston, T1
Slater, C1
McMillan, DC1
Falconer, JS1
Shenkin, A1
Fearon, KC1

Trials

2 trials available for glycine and Cachexia

ArticleYear
Anabolic effects of recombinant insulin-like growth factor-I in cachectic patients with the acquired immunodeficiency syndrome.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anthropometry; Body Mass Index; Cachexia; Carrier Protein

1994
Low plasma glutamine in combination with high glutamate levels indicate risk for loss of body cell mass in healthy individuals: the effect of N-acetyl-cysteine.
    Journal of molecular medicine (Berlin, Germany), 1996, Volume: 74, Issue:7

    Topics: Acetylcysteine; Adult; Aerobiosis; Anaerobiosis; Body Weight; Cachexia; Cystine; Exercise; Female; G

1996

Other Studies

6 other studies available for glycine and Cachexia

ArticleYear
Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia.
    Nature communications, 2023, 10-06, Volume: 14, Issue:1

    Topics: Animals; Cachexia; Glycine; Humans; Liver; Mice; Niacin; Proteomics; Pyridoxine; Stomach Neoplasms;

2023
Nutraceutical targeting of TLR4 signaling has potential for prevention of cancer cachexia.
    Medical hypotheses, 2019, Volume: 132

    Topics: 3-Hydroxybutyric Acid; Adipocytes; Biotin; Cachexia; Carnitine; Catechin; Coumaric Acids; Dietary Su

2019
Glycine administration attenuates skeletal muscle wasting in a mouse model of cancer cachexia.
    Clinical nutrition (Edinburgh, Scotland), 2014, Volume: 33, Issue:3

    Topics: Adipose Tissue; Animals; Body Mass Index; Cachexia; Cell Line, Tumor; Disease Models, Animal; Fatty

2014
Multi-omics Analysis of Serum Samples Demonstrates Reprogramming of Organ Functions Via Systemic Calcium Mobilization and Platelet Activation in Metastatic Melanoma.
    Molecular & cellular proteomics : MCP, 2017, Volume: 16, Issue:1

    Topics: Asparagine; Biomarkers, Tumor; Blood Platelets; Cachexia; Calcium; Glycine; Humans; Melanoma; Metabo

2017
Supplemental nutrition with ornithine alpha-ketoglutarate in rats with cancer-associated cachexia: surgical treatment of the tumor improves efficacy of nutritional support.
    The Journal of nutrition, 1995, Volume: 125, Issue:12

    Topics: Amino Acids; Animals; Body Weight; Cachexia; Combined Modality Therapy; Eating; Food, Fortified; Glu

1995
Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response.
    The Journal of nutrition, 1998, Volume: 128, Issue:8

    Topics: Acute-Phase Reaction; Adenocarcinoma; Adult; Aged; Amino Acids; C-Reactive Protein; Cachexia; Fastin

1998