glycine and Breast Cancer studies

Research Excerpts

Excerpt	Relevance	Reference
" Here we discovered that missense mutant p53 oncoproteins stimulate de novo serine/glycine synthesis and essential amino acids intake, promoting breast cancer growth."	8.31	Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth. ( Audano, M; Baldassarre, G; Belletti, B; Bertolio, R; Bicciato, S; Blandino, G; Cancila, V; Caputo, M; Del Sal, G; Donzelli, S; Mantovani, F; Mitro, N; Pedretti, S; Piazza, S; Rustighi, A; Segatto, I; Tombari, C; Triboli, L; Tripodo, C; Vacca, D; Vodret, S; Zannini, A, 2023)
" Here, we report the synthesis of stable aqueous suspension of cinnamaldehyde tagged Fe3O4 nanoparticles capped with glycine and pluronic polymer (CPGF NPs) for their potential application in drug delivery and hyperthermia in breast cancer."	7.80	Synthesis, characterization and in vitro study of biocompatible cinnamaldehyde functionalized magnetite nanoparticles (CPGF Nps) for hyperthermia and drug delivery applications in breast cancer. ( Chikate, RC; Deore, AV; Dhole, SD; Gupta, P; Kadu, BS; Kaul-Ghanekar, R; Mansara, P; Poddar, P; Wani, KD, 2014)
" Immunodeficient mice were inoculated intrafemorally with the human breast adenocarcinoma cell line MDA-MB-231, then treated 14days later via mini-osmotic pumps inserted intraperitoneally with sulfasalazine, (S)-4-carboxyphenylglycine, or vehicle."	7.80	Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. ( Seidlitz, EP; Singh, G; Ungard, RG, 2014)
"We used western blotting and immunohistochemistry to examine five serine-/glycine-metabolism-associated proteins (PHGDH, PSAT, PSPH, SHMT, and GLDC) in six breast cancer cell lines and 709 breast cancer cases using tissue microarray (TMA)."	7.80	Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes. ( Jung, WH; Kim, SK; Koo, JS, 2014)
"Combinatorial use of sivelestat and trastuzumab might be a novel therapeutic strategy for HER2-positive breast cancer."	7.78	Growth effect of neutrophil elastase on breast cancer: favorable action of sivelestat and application to anti-HER2 therapy. ( Futamura, M; Kawaguchi, Y; Morimitsu, K; Nawa, M; Nonaka, K; Osada, S; Yoshida, K, 2012)
"Water-soluble 20(S)-glycinate esters of two highly potent 10,11-methylenedioxy analogues of camptothecin (CPT) have been synthesized and evaluated for their ability to eradicate human breast cancer tumor xenografts."	7.70	Water soluble 20(S)-glycinate esters of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts. ( Mangold, G; Manikumar, G; Marty, J; Potter, PM; Vladu, B; Von Hoff, DD; Wadkins, RM; Wall, ME; Wani, MC; Weitman, S, 1999)
"The mouse models of human breast cancer also indicated significant target enhancements of cRGD-Gd-DTPA-PLGA magnetic nanoparticles in the mouse tumor."	5.72	Ultrasound and magnetic resonance imaging of cyclic arginine glycine aspartic acid-gadopentetic acid-polylactic acid in human breast cancer by targeting αvβ3 in xenograft-bearing nude mice. ( Chen, M; Fu, D; Huang, X; Lv, Z; Su, D; Zhang, W; Zhang, Y, 2022)
"Glyphosate is a broad-spectrum herbicide that is used worldwide."	5.51	Glyphosate-based herbicides at low doses affect canonical pathways in estrogen positive and negative breast cancer cell lines. ( Agostini, LP; Aristizabal-Pachon, AF; Chariker, J; Detogni, RS; Louro, ID; Miller, DM; Peronni, KC; Reis, RSD; Rezzoug, F; Silva Junior, WA; Stur, E; Thomas, SD; Waigel, S, 2019)
"Amiloride is a potassium-sparing diuretic that has been used as an anti-kaliuretic for the chronic management of hypertension and heart failure."	5.39	A cell-permeant amiloride derivative induces caspase-independent, AIF-mediated programmed necrotic death of breast cancer cells. ( Carraway, KL; Gorin, F; Leon, LJ; Pasupuleti, N, 2013)
"Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides."	5.39	Glyphosate induces human breast cancer cells growth via estrogen receptors. ( Rangkadilok, N; Satayavivad, J; Suriyo, T; Thiantanawat, A; Thongprakaisang, S, 2013)
"Biopsies from breast cancer patients (n=98) were excised during surgery and analyzed by high-resolution magic angle spinning MRS."	5.38	Lactate and glycine-potential MR biomarkers of prognosis in estrogen receptor-positive breast cancers. ( Bathen, TF; Buydens, LM; Fjøsne, HE; Giskeødegård, GF; Gribbestad, IS; Lundgren, S; Postma, G; Sitter, B, 2012)
"The human BCRP (breast cancer resistance protein, also known as ABCG2) is an ABC (ATP-binding cassette) transporter that extrudes various anticancer drugs from cells, causing multidrug resistance."	5.33	Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2). ( Balakrishnan, L; Janvilisri, T; Shahi, S; van Veen, HW; Venter, H, 2005)
"Phomopsin is a mycotoxin known to be carcinogenic."	5.27	Influence of phomopsin and ivalin on steroid-hormone binding and growth of MCF-7 human breast cancer cells. ( Lewko, WM; van Aswegen, CH; Wittliff, JL, 1985)
" Here we discovered that missense mutant p53 oncoproteins stimulate de novo serine/glycine synthesis and essential amino acids intake, promoting breast cancer growth."	4.31	Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth. ( Audano, M; Baldassarre, G; Belletti, B; Bertolio, R; Bicciato, S; Blandino, G; Cancila, V; Caputo, M; Del Sal, G; Donzelli, S; Mantovani, F; Mitro, N; Pedretti, S; Piazza, S; Rustighi, A; Segatto, I; Tombari, C; Triboli, L; Tripodo, C; Vacca, D; Vodret, S; Zannini, A, 2023)
" The highest cellular uptake was observed in MCF-7 breast tumor cells treated with 99mTc-(tricine)-HYNIC-Lys-FROP as compared to other cell lines (lung, ovarian, T47D breast cancer cell lines)."	3.88	( Abedi, SM; Ahmadpour, S; Hosseinimehr, SJ; Noaparast, Z, 2018)
" Here, we report the synthesis of stable aqueous suspension of cinnamaldehyde tagged Fe3O4 nanoparticles capped with glycine and pluronic polymer (CPGF NPs) for their potential application in drug delivery and hyperthermia in breast cancer."	3.80	Synthesis, characterization and in vitro study of biocompatible cinnamaldehyde functionalized magnetite nanoparticles (CPGF Nps) for hyperthermia and drug delivery applications in breast cancer. ( Chikate, RC; Deore, AV; Dhole, SD; Gupta, P; Kadu, BS; Kaul-Ghanekar, R; Mansara, P; Poddar, P; Wani, KD, 2014)
" Immunodeficient mice were inoculated intrafemorally with the human breast adenocarcinoma cell line MDA-MB-231, then treated 14days later via mini-osmotic pumps inserted intraperitoneally with sulfasalazine, (S)-4-carboxyphenylglycine, or vehicle."	3.80	Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. ( Seidlitz, EP; Singh, G; Ungard, RG, 2014)
"We used western blotting and immunohistochemistry to examine five serine-/glycine-metabolism-associated proteins (PHGDH, PSAT, PSPH, SHMT, and GLDC) in six breast cancer cell lines and 709 breast cancer cases using tissue microarray (TMA)."	3.80	Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes. ( Jung, WH; Kim, SK; Koo, JS, 2014)
"Combinatorial use of sivelestat and trastuzumab might be a novel therapeutic strategy for HER2-positive breast cancer."	3.78	Growth effect of neutrophil elastase on breast cancer: favorable action of sivelestat and application to anti-HER2 therapy. ( Futamura, M; Kawaguchi, Y; Morimitsu, K; Nawa, M; Nonaka, K; Osada, S; Yoshida, K, 2012)
" In the present study, the feasibility and effectiveness of an amino acidic adjuvant, glycine was investigated to enhance the cryodestruction of MCF-7 human breast cancer cell at mild freezing/thawing conditions via eutectic solidification."	3.74	An amino acidic adjuvant to augment cryoinjury of MCF-7 breast cancer cells. ( Han, B; Teo, KY; Wang, CL, 2008)
"Water-soluble 20(S)-glycinate esters of two highly potent 10,11-methylenedioxy analogues of camptothecin (CPT) have been synthesized and evaluated for their ability to eradicate human breast cancer tumor xenografts."	3.70	Water soluble 20(S)-glycinate esters of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts. ( Mangold, G; Manikumar, G; Marty, J; Potter, PM; Vladu, B; Von Hoff, DD; Wadkins, RM; Wall, ME; Wani, MC; Weitman, S, 1999)
" MDA-MB-435 human breast carcinoma cells were transfected with a control expression vector (pCMVBamneo), the vector containing the wild type nm23-H1, or the nm23-H1 vector encoding mutations at the following amino acids: serine 44, a phosphorylation site; proline 96, the k-pn mutation in the Drosophila nm23 homolog that causes developmental defects; histidine 118, involved in Nm23's nucleoside diphosphate kinase activity; and serine 120, a site of mutation in human neuroblastomas and phosphorylation."	3.69	Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells. ( Freije, JM; MacDonald, NJ; Manrow, RE; Steeg, PS; Stracke, ML, 1996)
"We have investigated the role of dihydrofolate (H2PteGlu) accumulation in the inhibition of de novo purine synthesis by methotrexate (MTX) in human MCF-7 breast cancer cells."	3.67	Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate. ( Allegra, CJ; Baram, J; Drake, JC; Hoang, K; Yeh, GC, 1987)
"Basal cell-like breast cancer (BLBC), one subtype of breast cancer, has the characteristics of a high recurrence rate and strong invasiveness."	1.91	Inhibitory Effort of MLN2238 on Basal-Like Breast Cancer: An Investigation Based on the Gene Set Enrichment Analysis. ( Chen, Y; Li, Y; Luo, F; Song, X; Wang, D; Wu, S; Zhang, N, 2023)
"The mouse models of human breast cancer also indicated significant target enhancements of cRGD-Gd-DTPA-PLGA magnetic nanoparticles in the mouse tumor."	1.72	Ultrasound and magnetic resonance imaging of cyclic arginine glycine aspartic acid-gadopentetic acid-polylactic acid in human breast cancer by targeting αvβ3 in xenograft-bearing nude mice. ( Chen, M; Fu, D; Huang, X; Lv, Z; Su, D; Zhang, W; Zhang, Y, 2022)
"Bortezomib (BTZ) is a proteasome inhibitor used for multiple myeloma and mantle cell lymphoma treatment."	1.51	Glycine-Poly-L-Lactic Acid Copolymeric Nanoparticles for the Efficient Delivery of Bortezomib. ( Chaudhari, D; Gupta, U; Jain, S; Rajoria, S; Rani, S, 2019)
"Glyphosate is a broad-spectrum herbicide that is used worldwide."	1.51	Glyphosate-based herbicides at low doses affect canonical pathways in estrogen positive and negative breast cancer cell lines. ( Agostini, LP; Aristizabal-Pachon, AF; Chariker, J; Detogni, RS; Louro, ID; Miller, DM; Peronni, KC; Reis, RSD; Rezzoug, F; Silva Junior, WA; Stur, E; Thomas, SD; Waigel, S, 2019)
"Breast cancer is the most frequent diagnosed cancer among women with a mortality rate of 15% of all cancer related deaths in women."	1.48	Alteration in lipid composition differentiates breast cancer tissues: a ( Jain, S; Kumar, S; Paul, A; Raj, A; Roy, R; Singhai, A; Sonkar, AA, 2018)
" Interestingly, pharmacokinetic outcomes of the conjugate were superior and the area under the curve was enhanced by approximately three-times, whereas the drug clearance was reduced by around five-times, after single intravenous injection."	1.46	Glycinated fullerenes for tamoxifen intracellular delivery with improved anticancer activity and pharmacokinetics. ( Katare, OP; Kumar, M; Kumar, R; Misra, C; Raza, K; Sharma, G; Singh, B, 2017)
" The unsuccessful clinical trials of proteasome inhibitor PS-341 (bortezomib) in solid tumors led to the invention of MLN9708 (ixazomib), an orally bioavailable next-generation proteasome inhibitor with improved pharmacokinetic and pharmacodynamic features."	1.43	Next-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosis. ( Cao, WM; Cui, Y; Dou, J; Jiang, Z; Wang, H; Wang, Z; Yu, Y; Zhang, H; Zhao, Y, 2016)
"glycine, tumor grade, metabolism, phyllodes tumor, serine."	1.40	Expression of serine and glycine-related enzymes in phyllodes tumor. ( Jung, WH; Kim, DH; Koo, JS; Kwon, JE, 2014)
"Samples of 13 patients with metastatic breast cancer were analyzed for mutations in cancer-related genes."	1.39	D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer. ( Ben-Baruch, N; Brown, M; Dvir, A; Jeselsohn, R; Klein, B; Merenbakh-Lamin, K; Miller, VA; Rizel, S; Rubinek, T; Sarid, D; Soussan-Gutman, L; Wolf, I; Yeheskel, A; Yelensky, R, 2013)
"Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides."	1.39	Glyphosate induces human breast cancer cells growth via estrogen receptors. ( Rangkadilok, N; Satayavivad, J; Suriyo, T; Thiantanawat, A; Thongprakaisang, S, 2013)
"Amiloride is a potassium-sparing diuretic that has been used as an anti-kaliuretic for the chronic management of hypertension and heart failure."	1.39	A cell-permeant amiloride derivative induces caspase-independent, AIF-mediated programmed necrotic death of breast cancer cells. ( Carraway, KL; Gorin, F; Leon, LJ; Pasupuleti, N, 2013)
"Biopsies from breast cancer patients (n=98) were excised during surgery and analyzed by high-resolution magic angle spinning MRS."	1.38	Lactate and glycine-potential MR biomarkers of prognosis in estrogen receptor-positive breast cancers. ( Bathen, TF; Buydens, LM; Fjøsne, HE; Giskeødegård, GF; Gribbestad, IS; Lundgren, S; Postma, G; Sitter, B, 2012)
"Glioblastomas and brain metastases demonstrate avid uptake of 2-[(18) F]fluoro-2-deoxyglucose by positron emission tomography and display perturbations of intracellular metabolite pools by (1) H MRS."	1.38	Metabolism of [U-13 C]glucose in human brain tumors in vivo. ( Bachoo, RM; Choi, C; DeBerardinis, RJ; Hatanpaa, KJ; Jeffrey, FM; Jindal, A; Madden, C; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Mathews, D; Mickey, BE; Pascual, JM; Raisanen, J, 2012)
"The effect of tamoxifen on breast cancer growth may, in part, be related to perturbations in cell volume regulation."	1.37	Specificity of the volume-activated amino acid efflux pathway in cultured human breast cancer cells. ( Shennan, DB; Thomson, J, 2011)
"Our results suggest that the breast cancer-associated mutations interfere with the intracellular trafficking of ADAM12 and result in loss of the functional ADAM12 at the cell surface."	1.35	Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein. ( Dyczynska, E; Sun, D; Syta, E; Zolkiewska, A, 2008)
"The human BCRP (breast cancer resistance protein, also known as ABCG2) is an ABC (ATP-binding cassette) transporter that extrudes various anticancer drugs from cells, causing multidrug resistance."	1.33	Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2). ( Balakrishnan, L; Janvilisri, T; Shahi, S; van Veen, HW; Venter, H, 2005)
"Recently, four cancer-associated mutants of the A-alpha subunit have been described: Glu64-->Asp in lung carcinoma, Glu64-->Gly in breast carcinoma, Arg418-->Trp in melanoma, and Delta171 - 589 in breast carcinoma."	1.31	Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene. ( Pham, HT; Ruediger, R; Walter, G, 2001)
"It is clear that growth of the MCF-7 breast cancer cell line is stimulated by estrogen and when estrogen is removed, growth slows."	1.30	Characterization of a point mutation in the hormone binding domain of the estrogen receptor from an breast tumor. ( Assikis, VJ; Bilimoria, MM; Chen, Z; England, GM; Jordan, VC; Muenzner, HD, 1998)
"Transfection of the human breast cancer cell line MDA-MB-435 in vitro was accomplished employing cationic liposome-mRNA complexes."	1.29	Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors. ( Benjamin, R; Conry, RM; Curiel, DT; Kim, M; Lu, D, 1994)
"Phomopsin is a mycotoxin known to be carcinogenic."	1.27	Influence of phomopsin and ivalin on steroid-hormone binding and growth of MCF-7 human breast cancer cells. ( Lewko, WM; van Aswegen, CH; Wittliff, JL, 1985)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (13.89)	18.7374
1990's	6 (8.33)	18.2507
2000's	21 (29.17)	29.6817
2010's	27 (37.50)	24.3611
2020's	8 (11.11)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
Treatment Development of Triheptanoin for Glucose Transporter Type I Deficiency[NCT02021526]			Phase 1/Phase 2	0 participants (Actual)	Interventional	2015-12-31	Withdrawn (stopped due to NIH funding resulted in new clinical trial)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Ultrasound and magnetic resonance imaging of cyclic arginine glycine aspartic acid-gadopentetic acid-polylactic acid in human breast cancer by targeting αvβ3 in xenograft-bearing nude mice. Bioengineered, 2022, Volume: 13, Issue:3 Topics: Animals; Arginine; Aspartic Acid; Breast Neoplasms; Contrast Media; Female; Gadolinium DTPA; Glycine	2022
Inhibitory Effort of MLN2238 on Basal-Like Breast Cancer: An Investigation Based on the Gene Set Enrichment Analysis. Cellular and molecular biology (Noisy-le-Grand, France), 2023, Jul-31, Volume: 69, Issue:7 Topics: Breast Neoplasms; Cell Cycle; Cell Division; Female; Glycine; Humans	2023
Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth. Nature communications, 2023, 10-25, Volume: 14, Issue:1 Topics: Amino Acids; Amino Acids, Essential; Breast Neoplasms; Female; Glycine; Humans; Large Neutral Amino	2023
Glycine-Poly-L-Lactic Acid Copolymeric Nanoparticles for the Efficient Delivery of Bortezomib. Pharmaceutical research, 2019, Sep-13, Volume: 36, Issue:11 Topics: Antineoplastic Agents; Bortezomib; Breast Neoplasms; Cell Line, Tumor; Drug Compounding; Drug Delive	2019
Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth. Molecular cancer therapeutics, 2021, Volume: 20, Issue:1 Topics: Animals; Antidepressive Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ce	2021
Novel silver glycinate conjugate with 3D polymeric intermolecular self-assembly architecture; an antiproliferative agent which induces apoptosis on human breast cancer cells. Journal of inorganic biochemistry, 2021, Volume: 216 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Coordination Complexes; Fema	2021
Two new oral candidates as anticancer platinum complexes of 1,3-dimethyl pentyl glycine ligand as doping agents against breast cancer. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021, Apr-15, Volume: 251 Topics: Antineoplastic Agents; Breast Neoplasms; Doping in Sports; Glycine; Humans; Ligands; Platinum	2021
Pilot study on the urinary excretion of the glyphosate metabolite aminomethylphosphonic acid and breast cancer risk: The Multiethnic Cohort study. Environmental pollution (Barking, Essex : 1987), 2021, May-15, Volume: 277 Topics: Breast Neoplasms; Case-Control Studies; Cohort Studies; Female; Glycine; Glyphosate; Hawaii; Herbici	2021
AJOG global reports, 2021, Volume: 1, Issue:1 Topics: Animals; Apoptosis; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Fatty Acids; Fema	2021
Glycinated fullerenes for tamoxifen intracellular delivery with improved anticancer activity and pharmacokinetics. Nanomedicine (London, England), 2017, Volume: 12, Issue:9 Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Carriers; Drug Delivery Systems; Dr	2017
Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:9 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Female; Glycine; Humans; Hydrazines;	2018
GCSH antisense regulation determines breast cancer cells' viability. Scientific reports, 2018, 10-18, Volume: 8, Issue:1 Topics: Breast; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Gene Expression Regulation, Neopl	2018
Alteration in lipid composition differentiates breast cancer tissues: a Metabolomics : Official journal of the Metabolomic Society, 2018, 09-03, Volume: 14, Issue:9 Topics: Breast Neoplasms; Choline; Female; Glutamic Acid; Glycine; Humans; Lipids; Metabolomics; Middle Aged	2018
Glyphosate-based herbicides at low doses affect canonical pathways in estrogen positive and negative breast cancer cell lines. PloS one, 2019, Volume: 14, Issue:7 Topics: Breast Neoplasms; Cell Proliferation; DNA Repair; Estrogen Receptor alpha; Estrogens; Female; Gene E	2019
A cell-permeant amiloride derivative induces caspase-independent, AIF-mediated programmed necrotic death of breast cancer cells. PloS one, 2013, Volume: 8, Issue:4 Topics: Amiloride; Apoptosis; Apoptosis Inducing Factor; Breast Neoplasms; Calcium; Calpain; Caspases; Cell	2013
Glyphosate induces human breast cancer cells growth via estrogen receptors. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 59 Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Endocrine Dis	2013
Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. Pain, 2014, Volume: 155, Issue:1 Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bone and Bones; Breast	2014
D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer. Cancer research, 2013, Dec-01, Volume: 73, Issue:23 Topics: Amino Acid Substitution; Antineoplastic Agents, Hormonal; Aspartic Acid; Breast Neoplasms; Carcinoma	2013
Inhibition of invasion and epithelial-mesenchymal transition of human breast cancer cells by hydrogen sulfide through decreased phospho-p38 expression. Molecular medicine reports, 2014, Volume: 10, Issue:1 Topics: Alkynes; Breast Neoplasms; Cell Movement; Cell Survival; Cystathionine gamma-Lyase; Epithelial-Mesen	2014
Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes. PloS one, 2014, Volume: 9, Issue:6 Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Disease-Free Survival; Female; Glycine; Glyco	2014
Expression of serine and glycine-related enzymes in phyllodes tumor. Neoplasma, 2014, Volume: 61, Issue:5 Topics: Adult; Breast Neoplasms; Female; Glycine; Humans; Middle Aged; Phyllodes Tumor; Serine	2014
Synthesis, characterization and in vitro study of biocompatible cinnamaldehyde functionalized magnetite nanoparticles (CPGF Nps) for hyperthermia and drug delivery applications in breast cancer. PloS one, 2014, Volume: 9, Issue:9 Topics: Acrolein; Antineoplastic Agents; Biocompatible Materials; Breast Neoplasms; Cell Movement; Cell Prol	2014
Multiclass comparative virtual screening to identify novel Hsp90 inhibitors: a therapeutic breast cancer drug target. Current topics in medicinal chemistry, 2015, Volume: 15, Issue:1 Topics: Adenine; Anisoles; Antineoplastic Agents; Benzamides; Binding Sites; Breast Neoplasms; Catechin; Dat	2015
Next-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosis. Scientific reports, 2016, 05-24, Volume: 6 Topics: Autophagy; Boron Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; D	2016
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells. Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:2 Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Pr	2017
Modulation of cell death in human colorectal and breast cancer cells through a manganese chelate by involving GSH with intracellular p53 status. Molecular and cellular biochemistry, 2017, Volume: 427, Issue:1-2 Topics: Apoptosis; Breast Neoplasms; Chelating Agents; Colorectal Neoplasms; Female; Gene Expression Regulat	2017
2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor. Journal of cellular physiology, 2017, Volume: 232, Issue:11 Topics: 2-Methoxyestradiol; Antineoplastic Agents; Binding Sites; Bone Neoplasms; Breast Neoplasms; Cell Mov	2017
An amino acidic adjuvant to augment cryoinjury of MCF-7 breast cancer cells. Cryobiology, 2008, Volume: 57, Issue:1 Topics: Breast Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Cryopreservation; Cryosurger	2008
Haplotype and quantitative transcript analyses of Portuguese breast/ovarian cancer families with the BRCA1 R71G founder mutation of Galician origin. Familial cancer, 2009, Volume: 8, Issue:3 Topics: Alternative Splicing; Amino Acid Substitution; Arginine; BRCA1 Protein; Breast Neoplasms; DNA Mutati	2009
+331G/A variant in the progesterone receptor gene, postmenopausal hormone use and risk of breast cancer. International journal of cancer, 2009, Oct-01, Volume: 125, Issue:7 Topics: Adult; Alanine; Breast Neoplasms; Case-Control Studies; Confidence Intervals; Estrogen Replacement T	2009
Partially polymerized liposomes: stable against leakage yet capable of instantaneous release for remote controlled drug delivery. Nanotechnology, 2011, Apr-15, Volume: 22, Issue:15 Topics: 1,2-Dipalmitoylphosphatidylcholine; Aniline Compounds; Biological Availability; Breast Neoplasms; Ce	2011
Specificity of the volume-activated amino acid efflux pathway in cultured human breast cancer cells. General physiology and biophysics, 2011, Volume: 30, Issue:1 Topics: Adenosine Triphosphate; Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Breast Ne	2011
Growth effect of neutrophil elastase on breast cancer: favorable action of sivelestat and application to anti-HER2 therapy. Anticancer research, 2012, Volume: 32, Issue:1 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Proto	2012
Lactate and glycine-potential MR biomarkers of prognosis in estrogen receptor-positive breast cancers. NMR in biomedicine, 2012, Volume: 25, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Cohort Studies; Discriminant An	2012
Metabolism of [U-13 C]glucose in human brain tumors in vivo. NMR in biomedicine, 2012, Volume: 25, Issue:11 Topics: Acetyl Coenzyme A; Blood Glucose; Brain Neoplasms; Breast Neoplasms; Carbon Isotopes; Carcinoma, Non	2012
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science (New York, N.Y.), 2012, May-25, Volume: 336, Issue:6084 Topics: Breast Neoplasms; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Transformation,	2012
Structural analysis of the ErbB-2 receptor using monoclonal antibodies: Implications for receptor signalling. International journal of cancer, 2003, Apr-10, Volume: 104, Issue:3 Topics: Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Binding, Competitive; Breast Neopl	2003
Mutagenesis of a Gly-Ser cleavage site in MUC1 inhibits ectodomain shedding. Biochemical and biophysical research communications, 2003, Aug-01, Volume: 307, Issue:3 Topics: Amino Acid Sequence; Animals; Breast Neoplasms; COS Cells; Glycine; Humans; Lung Neoplasms; Mice; Mu	2003
Influence of 2alpha-methyl-17beta-hydroxy-5alpha-androstan-3-one on incorporation of glycine-2-C14 into proteins of a rat mammary fibroadenoma. A possible bioassay method. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 111 Topics: Animals; Biological Assay; Breast; Breast Neoplasms; Dihydrotestosterone; Fibroadenoma; Glycine; Hum	1962
FREE AMINO ACIDS OF HUMAN BREAST CANCER. The Nebraska state medical journal, 1964, Volume: 49 Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Gl	1964
[ON THE EFFECT OF A NEW CYTOSTATIC (RO-4-6467) ON THE INCORPORATION OF LABELLED GLYCINE IN TUMOR CELLS]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1964, Volume: 70 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cytostatic Agents; Glycine; Humans; Hydrazines; Ma	1964
Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2). The Biochemical journal, 2005, Jan-15, Volume: 385, Issue:Pt 2 Topics: Amino Acid Substitution; Anti-Bacterial Agents; Arginine; ATP Binding Cassette Transporter, Subfamil	2005
FGFR4 GLY388 isotype suppresses motility of MDA-MB-231 breast cancer cells by EDG-2 gene repression. Cellular signalling, 2006, Volume: 18, Issue:6 Topics: Alleles; Amino Acid Substitution; Arginine; Breast Neoplasms; Cell Line; Cell Movement; Cells, Cultu	2006
The glycine 90 to aspartate alteration in the Abeta subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function. Genes, chromosomes & cancer, 2006, Volume: 45, Issue:2 Topics: Amino Acid Substitution; Aspartic Acid; Base Sequence; Breast Neoplasms; DNA Primers; Female; Geneti	2006
Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells. Journal of the National Cancer Institute, 2005, Dec-07, Volume: 97, Issue:23 Topics: Adenoviridae; Alanine; Animals; Arginine; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell L	2005
Dominant negative retinoic acid receptor initiates tumor formation in mice. Molecular cancer, 2006, Mar-24, Volume: 5 Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelial Cells	2006
Interleukin 6 G-174 C polymorphism and breast cancer risk. European journal of epidemiology, 2006, Volume: 21, Issue:5 Topics: Aged; Aged, 80 and over; Breast Neoplasms; Cysteine; Female; Genetic Predisposition to Disease; Geno	2006
FGFR4 Arg388 allele is associated with resistance to adjuvant therapy in primary breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Aug-10, Volume: 24, Issue:23 Topics: Adult; Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Arginine; Biomarkers, Tumor; B	2006
P27 V109G Polymorphism is associated with lymph node metastases but not with increased risk of breast cancer. Journal of experimental & clinical cancer research : CR, 2007, Volume: 26, Issue:1 Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Case-Control Studies; Cyclin-Dependent Kinase Inhibitor	2007
Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation. Cancer letters, 2007, Nov-18, Volume: 257, Issue:2 Topics: Adenocarcinoma; Alkanes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carbamates; Cell Line,	2007
Alteration of estrogen-regulated gene expression in human cells induced by the agricultural and horticultural herbicide glyphosate. Human & experimental toxicology, 2007, Volume: 26, Issue:9 Topics: Breast Neoplasms; Cell Line, Tumor; Estradiol; Female; Gene Expression Profiling; Gene Expression Re	2007
Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants? Breast cancer research : BCR, 2007, Volume: 9, Issue:6 Topics: Alanine; Arginine; Biomarkers, Tumor; Breast Neoplasms; Centrosome; DNA, Complementary; Factor Analy	2007
Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein. International journal of cancer, 2008, Jun-01, Volume: 122, Issue:11 Topics: ADAM Proteins; ADAM12 Protein; Animals; Aspartic Acid; Biotinylation; Blotting, Western; Breast Neop	2008
The effect of the glutamine analog, AT-125, on the cell cycle of MCF-7 and BT-20 human breast carcinoma cells using DNA flow cytometry. Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:2 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Cytological Techniques; DNA, Neoplas	1980
Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors. Cancer gene therapy, 1994, Volume: 1, Issue:4 Topics: beta-Galactosidase; Breast Neoplasms; Cation Exchange Resins; Cations; Drug Carriers; Fatty Acids, M	1994
[In vitro NMR spectroscopy of healthy, pathologically changed and carcinomatous breast tissue samples correlated with histological findings]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1994, Volume: 161, Issue:2 Topics: Breast; Breast Diseases; Breast Neoplasms; Diagnosis, Differential; Fatty Acids; Female; Glucose; Gl	1994
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells. The Journal of biological chemistry, 1996, Oct-11, Volume: 271, Issue:41 Topics: Alanine; Amino Acid Sequence; Animals; Breast Neoplasms; Cell Division; Chemotaxis; Drosophila; Fema	1996
Characterization of a point mutation in the hormone binding domain of the estrogen receptor from an breast tumor. International journal of oncology, 1998, Volume: 12, Issue:5 Topics: Animals; Binding Sites; Breast Neoplasms; Cell Division; DNA Primers; Estradiol; Estrogen Antagonist	1998
Non-radioactive detection of K-ras mutations by nested allele specific PCR and oligonucleotide hybridization. Molecular and cellular probes, 1998, Volume: 12, Issue:5 Topics: Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Breast Neoplasms; Codon; Colonic Neoplasms	1998
Water soluble 20(S)-glycinate esters of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts. Cancer research, 1999, Jul-15, Volume: 59, Issue:14 Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cholinesterase Inhibitor	1999
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates. Chemistry & biology, 2000, Volume: 7, Issue:10 Topics: Alanine; Antineoplastic Agents; Arylsulfatases; Binding Sites; Breast Neoplasms; Coumarins; Dehydroe	2000
In vitro studies of a prolactin antagonist, hPRL-G129R in human breast cancer cells. International journal of oncology, 2001, Volume: 18, Issue:1 Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Arginine; Breast Neoplasms;	2001
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene. Oncogene, 2001, Jan-04, Volume: 20, Issue:1 Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Huma	2001
The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR. Archives of biochemistry and biophysics, 2001, Sep-01, Volume: 393, Issue:1 Topics: Breast Neoplasms; Carbon Isotopes; Cytosol; Female; Formates; Glycine; Glycine Hydroxymethyltransfer	2001
Glycine-N-methyltransferase levels in human breast cancer tissue. European journal of cancer, 1977, Volume: 13, Issue:11 Topics: Breast Neoplasms; Female; Glycine; Humans; Methyltransferases; Neoplasm Metastasis	1977
Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate. The Journal of biological chemistry, 1987, Oct-05, Volume: 262, Issue:28 Topics: Acyltransferases; Antineoplastic Agents; Breast Neoplasms; Carbon Radioisotopes; Cell Line; Female;	1987
Effects of serine and glycine on proliferation of an Ishikawa cell variant. Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6 Topics: Adenocarcinoma; Adult; Breast Neoplasms; Cell Division; Cell Line; DNA Replication; DNA, Neoplasm; F	1989
The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties. The EMBO journal, 1989, Volume: 8, Issue:7 Topics: Base Sequence; Breast Neoplasms; Cell Line; Cloning, Molecular; DNA-Directed DNA Polymerase; DNA, Ne	1989
Influence of phomopsin and ivalin on steroid-hormone binding and growth of MCF-7 human breast cancer cells. Journal of toxicology and environmental health, 1985, Volume: 16, Issue:1 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Survival; Cells, Cultured; Dexamethason	1985
Bone collagenase in osteolytic stress of rats and humans. Surgical forum, 1970, Volume: 21 Topics: Animals; Biological Assay; Bone Resorption; Breast Neoplasms; Carbon Isotopes; Glycine; Humans; Hype	1970

glycine and Breast Cancer

Research Excerpts

Research

Studies (72)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Fu, D	1
Huang, X	1
Lv, Z	1
Zhang, Y	2
Chen, M	1
Zhang, W	1
Su, D	1
Wang, D	1
Li, Y	2
Luo, F	1
Song, X	1
Wu, S	1
Chen, Y	1
Zhang, N	1
Tombari, C	1
Zannini, A	1
Bertolio, R	1
Pedretti, S	1
Audano, M	1
Triboli, L	1
Cancila, V	1
Vacca, D	1
Caputo, M	1
Donzelli, S	1
Segatto, I	1
Vodret, S	1
Piazza, S	1
Rustighi, A	1
Mantovani, F	1
Belletti, B	1
Baldassarre, G	1
Blandino, G	1
Tripodo, C	1
Bicciato, S	1
Mitro, N	1
Del Sal, G	1
Rajoria, S	1
Rani, S	1
Chaudhari, D	1
Jain, S	2
Gupta, U	1
Geeraerts, SL	1
Kampen, KR	1
Rinaldi, G	1
Gupta, P	2
Planque, M	1
Louros, N	1
Heylen, E	1
De Cremer, K	1
De Brucker, K	1
Vereecke, S	1
Verbelen, B	1
Vermeersch, P	1
Schymkowitz, J	1
Rousseau, F	1
Cassiman, D	1
Fendt, SM	1
Voet, A	1
Cammue, BPA	1
Thevissen, K	1
De Keersmaecker, K	1
Banti, CN	1
Raptopoulou, CP	1
Psycharis, V	1
Hadjikakou, SK	1
Ramezani, N	1
Eslami Moghadam, M	1
Behzad, M	1
Zolghadri, S	1
Franke, AA	1
Li, X	1
Shvetsov, YB	1
Lai, JF	1
Short, VL	1
Hoffman, M	1
Metgud, M	1
Kavi, A	1
Goudar, SS	1
Okitawutshu, J	1
Tshefu, A	1
Bose, CL	1
Mwenechanya, M	1
Chomba, E	1
Carlo, WA	1
Figueroa, L	1
Garces, A	1
Krebs, NF	1
Jessani, S	1
Saleem, S	1
Goldenberg, RL	1
Das, PK	1
Patel, A	1
Hibberd, PL	1
Achieng, E	1
Nyongesa, P	1
Esamai, F	1
Bucher, S	1
Nowak, KJ	1
Goco, N	1
Nolen, TL	1
McClure, EM	1
Koso-Thomas, M	1
Miodovnik, M	1
Derman, RJ	1
Li, W	1
Ten, LN	1
Kim, MK	1
Lee, SY	1
Jung, HY	1
Mu, T	1
Jia, H	1
Yang, Y	1
Wu, Z	1
Oscilowska, I	1
Huynh, TYL	1
Baszanowska, W	1
Prokop, I	1
Surazynski, A	1
Galli, M	1
Zabielski, P	1
Palka, J	1
Misra, C	1
Kumar, M	1
Sharma, G	1
Kumar, R	1
Singh, B	1
Katare, OP	1
Raza, K	1
Ahmadpour, S	1
Noaparast, Z	1
Abedi, SM	1
Hosseinimehr, SJ	1
Adamus, A	1
Müller, P	1
Nissen, B	1
Kasten, A	1
Timm, S	1
Bauwe, H	1
Seitz, G	1
Engel, N	1
Paul, A	1
Kumar, S	1
Raj, A	1
Sonkar, AA	1
Singhai, A	1
Roy, R	1
Stur, E	1
Aristizabal-Pachon, AF	1
Peronni, KC	1
Agostini, LP	1
Waigel, S	1
Chariker, J	1
Miller, DM	1
Thomas, SD	1
Rezzoug, F	1
Detogni, RS	1
Reis, RSD	1
Silva Junior, WA	1
Louro, ID	1
Leon, LJ	1
Pasupuleti, N	1
Gorin, F	1
Carraway, KL	1
Thongprakaisang, S	1
Thiantanawat, A	1
Rangkadilok, N	1
Suriyo, T	1
Satayavivad, J	1
Ungard, RG	1
Seidlitz, EP	1
Singh, G	1
Merenbakh-Lamin, K	1
Ben-Baruch, N	1
Yeheskel, A	1
Dvir, A	1
Soussan-Gutman, L	1
Jeselsohn, R	1
Yelensky, R	1
Brown, M	1
Miller, VA	1
Sarid, D	1
Rizel, S	1
Klein, B	1
Rubinek, T	1
Wolf, I	1
Lv, M	1
Ji, MH	1
Zhuang, M	1
Tang, JH	1
Kim, SK	1
Jung, WH	2
Koo, JS	2
Kwon, JE	1
Kim, DH	1
Wani, KD	1
Kadu, BS	1
Mansara, P	1
Deore, AV	1
Chikate, RC	1
Poddar, P	1
Dhole, SD	1
Kaul-Ghanekar, R	1
Dunna, NR	1
Bandaru, S	1
Akare, UR	1
Rajadhyax, S	1
Gutlapalli, VR	1
Yadav, M	1
Nayarisseri, A	1
Geck, RC	1
Toker, A	1
Wang, H	1
Yu, Y	1
Jiang, Z	1
Cao, WM	1
Wang, Z	1
Dou, J	1
Zhao, Y	1
Cui, Y	1
Zhang, H	1
Phannasil, P	1
Ansari, IH	1
El Azzouny, M	1
Longacre, MJ	1
Rattanapornsompong, K	1
Burant, CF	1
MacDonald, MJ	1
Jitrapakdee, S	1
Banerjee, K	1
Das, S	1
Majumder, S	1
Majumdar, S	1
Biswas, J	1
Choudhuri, SK	1
Gorska-Ponikowska, M	1
Perricone, U	1
Kuban-Jankowska, A	1
Lo Bosco, G	1
Barone, G	1
Wang, CL	1
Teo, KY	1
Han, B	1
Santos, C	1
Peixoto, A	1
Rocha, P	1
Vega, A	1
Soares, MJ	1
Cerveira, N	1
Bizarro, S	1
Pinheiro, M	1
Pereira, D	1
Rodrigues, H	1
Castro, F	1
Henrique, R	1
Teixeira, MR	1
Kotsopoulos, J	1
Tworoger, SS	1
De Vivo, I	1
DeVivo, I	1
Hankinson, SE	1
Hunter, DJ	1
Willett, WC	1
Chen, WY	2
Qin, G	1
Li, Z	1
Xia, R	1
Li, F	1
O'Neill, BE	1
Goodwin, JT	1
Khant, HA	1
Chiu, W	1
Li, KC	1
Shennan, DB	1
Thomson, J	1
Nawa, M	1
Osada, S	1
Morimitsu, K	1
Nonaka, K	1
Futamura, M	1
Kawaguchi, Y	1
Yoshida, K	1
Giskeødegård, GF	1
Lundgren, S	1
Sitter, B	1
Fjøsne, HE	1
Postma, G	1
Buydens, LM	1
Gribbestad, IS	1
Bathen, TF	1
Maher, EA	1
Marin-Valencia, I	1
Bachoo, RM	1
Mashimo, T	1
Raisanen, J	1
Hatanpaa, KJ	1
Jindal, A	1
Jeffrey, FM	1
Choi, C	1
Madden, C	1
Mathews, D	1
Pascual, JM	1
Mickey, BE	1
Malloy, CR	1
DeBerardinis, RJ	1
Jain, M	1
Nilsson, R	1
Sharma, S	1
Madhusudhan, N	1
Kitami, T	1
Souza, AL	1
Kafri, R	1
Kirschner, MW	1
Clish, CB	1
Mootha, VK	1
Ferrari, P	1
Nicolini, A	1
Manca, ML	1
Rossi, G	1
Anselmi, L	1
Conte, M	1
Carpi, A	1
Bonino, F	1
Yip, YL	1
Novotny, J	1
Edwards, M	1
Ward, RL	1
Lillehoj, EP	1
Han, F	1
Kim, KC	1
ABE, O	1
HERRANEN, A	1
DORFMAN, RI	1
RYAN, WL	1
LORINCZ, AB	1
FOELSCH, E	1
DREWS, J	1
GRUNZE, H	1
Janvilisri, T	1
Shahi, S	1
Venter, H	1
Balakrishnan, L	1
van Veen, HW	1
Stadler, CR	1
Knyazev, P	1
Bange, J	2
Ullrich, A	2
Esplin, ED	1
Ramos, P	1
Martinez, B	1
Tomlinson, GE	1
Mumby, MC	1
Evans, GA	1
Azuma, H	1
Ehata, S	1
Miyazaki, H	1
Watabe, T	1
Maruyama, O	1
Imamura, T	1
Sakamoto, T	1
Kiyama, S	1
Kiyama, Y	1
Ubai, T	1
Inamoto, T	1
Takahara, S	1
Itoh, Y	1
Otsuki, Y	1
Katsuoka, Y	1
Miyazono, K	1
Horie, S	1
Kupumbati, TS	1
Cattoretti, G	1
Marzan, C	1
Farias, EF	1
Taneja, R	1
Mira-y-Lopez, R	1
González-Zuloeta Ladd, AM	1
Arias Vásquez, A	1
Witteman, J	1
Uitterlinden, AG	1
Coebergh, JW	1
Hofman, A	1
Stricker, BH	1
van Duijn, CM	1
Thussbas, C	1
Nahrig, J	1
Streit, S	1
Kriner, M	1
Kates, R	1
Ulm, K	1
Kiechle, M	1
Hoefler, H	1
Harbeck, N	1
Naidu, R	1
Har, YC	1
Taib, NA	1
Wiesen, KM	1
Xia, S	1
Yang, CP	1
Horwitz, SB	1
Hokanson, R	1
Fudge, R	1
Chowdhary, R	1
Busbee, D	1
Lovelock, PK	1
Spurdle, AB	1
Mok, MT	1
Farrugia, DJ	1
Lakhani, SR	1
Healey, S	1
Arnold, S	1
Buchanan, D	1
Couch, FJ	1
Henderson, BR	1
Goldgar, DE	1
Tavtigian, SV	1
Chenevix-Trench, G	1
Brown, MA	1
Dyczynska, E	1
Syta, E	1
Sun, D	1
Zolkiewska, A	1
Thornthwaite, JT	1
Allen, LM	1
Lu, D	1
Benjamin, R	1
Kim, M	1
Conry, RM	1
Curiel, DT	1
Speckter, H	1
Blümich, B	1
Just, M	1
Trömel, U	1
Mitze, M	1
Thelen, M	1
MacDonald, NJ	1
Freije, JM	1
Stracke, ML	1
Manrow, RE	1
Steeg, PS	1
England, GM	1
Bilimoria, MM	1
Chen, Z	1
Assikis, VJ	1
Muenzner, HD	1
Jordan, VC	1
Paranavitana, CM	1
Wadkins, RM	1
Potter, PM	1
Vladu, B	1
Marty, J	1
Mangold, G	1
Weitman, S	1
Manikumar, G	1
Wani, MC	1
Wall, ME	1
Von Hoff, DD	1
Woo, LL	1
Purohit, A	1
Malini, B	1
Reed, MJ	1
Potter, BV	1
Ramamoorthy, P	1
Sticca, R	1
Wagner, TE	1
Ruediger, R	1
Pham, HT	1
Walter, G	1
Fu, TF	1
Rife, JP	1
Schirch, V	1
Guerinot, F	1
Bohuon, C	1
Allegra, CJ	1
Hoang, K	1
Yeh, GC	1
Drake, JC	1
Baram, J	1
Watanabe, J	1
Holinka, CF	1
Anzai, Y	1
Kuramoto, H	1
Gurpide, E	1
Tora, L	1
Mullick, A	1
Metzger, D	1
Ponglikitmongkol, M	1
Park, I	1
Chambon, P	1
van Aswegen, CH	1
Lewko, WM	1
Wittliff, JL	1
Gardner, B	1
Gray, H	1
Hedayati, H	1