glycine has been researched along with Brain Edema in 25 studies
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glycine has been shown to protect against ischemic stroke through various mechanisms." | 5.48 | Glycine confers neuroprotection through PTEN/AKT signal pathway in experimental intracerebral hemorrhage. ( Chen, J; Chen, Y; Feng, YG; Lei, Y; Liao, HB; Liu, R; Pan, MX; Qin, XP; Tang, JC; Wan, Q; Wang, S; Zhang, Y; Zhang, ZF; Zhao, D; Zhuang, Y, 2018) |
| "We studied all patients of the Glycine Antagonist (gavestinel) In Neuroprotection (GAIN) International Trial with ischemic stroke alive at day 7, excluding patients with hemorrhagic events and deaths from nonstroke-related causes." | 5.11 | Poststroke neurological improvement within 7 days is associated with subsequent deterioration. ( Aslanyan, S; Johnston, SC; Lees, KR; Weir, CJ, 2004) |
| "Death following the use the glycine distension solution in transurethral prostatectomy (TURP) or hysteroscopic surgery has been attributed to the toxic effect of glycine on the brain through the glycine receptors and hyperammonemia, contending that glycine-associated hyponatremia is isosmotic and therefore would not cause brain oedema." | 3.85 | A hypothesis for mechanism for brain oedema due to glycine. ( Mehta, SJ; Oh, MS; Roche Recinos, A; Saggi, SJ, 2017) |
| "Volume overload may cause pulmonary edema, and water intoxication may lead to hyponatremia, hypo-osmolarity, and cerebral edema." | 2.38 | Complications associated with the absorption of hysteroscopic fluid media. ( Burns, WN; Olive, DL; Schenken, RS; Silverberg, KM; Witz, CA, 1993) |
| "Glycine has been shown to protect against ischemic stroke through various mechanisms." | 1.48 | Glycine confers neuroprotection through PTEN/AKT signal pathway in experimental intracerebral hemorrhage. ( Chen, J; Chen, Y; Feng, YG; Lei, Y; Liao, HB; Liu, R; Pan, MX; Qin, XP; Tang, JC; Wan, Q; Wang, S; Zhang, Y; Zhang, ZF; Zhao, D; Zhuang, Y, 2018) |
| "Glycine (100 microM) was inactive in this assay indicating an absence of functional glycine-A receptors in this preparation." | 1.35 | Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide. ( Hartmann, J; Hildmann, O; Hillert, M; Kiewert, C; Klein, J; Kumar, V, 2008) |
| "Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus." | 1.30 | Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 11 (44.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 7 (28.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mehta, SJ | 1 |
| Roche Recinos, A | 1 |
| Saggi, SJ | 1 |
| Oh, MS | 1 |
| Zhao, D | 1 |
| Chen, J | 1 |
| Zhang, Y | 1 |
| Liao, HB | 1 |
| Zhang, ZF | 1 |
| Zhuang, Y | 1 |
| Pan, MX | 1 |
| Tang, JC | 1 |
| Liu, R | 1 |
| Lei, Y | 1 |
| Wang, S | 1 |
| Qin, XP | 1 |
| Feng, YG | 1 |
| Chen, Y | 1 |
| Wan, Q | 1 |
| Zhang, ZY | 1 |
| Sun, BL | 1 |
| Liu, JK | 1 |
| Yang, MF | 1 |
| Li, DW | 1 |
| Fang, J | 1 |
| Zhang, S | 1 |
| Yuan, QL | 1 |
| Huang, SL | 1 |
| Ikegame, Y | 1 |
| Yamashita, K | 1 |
| Hayashi, S | 1 |
| Yoshimura, S | 1 |
| Nakashima, S | 1 |
| Iwama, T | 1 |
| Righi, V | 1 |
| Tugnoli, V | 1 |
| Mucci, A | 1 |
| Bacci, A | 1 |
| Bonora, S | 1 |
| Schenetti, L | 1 |
| Sribanditmongkol, P | 1 |
| Jutavijittum, P | 1 |
| Pongraveevongsa, P | 1 |
| Wunnapuk, K | 1 |
| Durongkadech, P | 1 |
| Wang, JW | 1 |
| Wang, HD | 1 |
| Cong, ZX | 1 |
| Zhang, XS | 1 |
| Zhou, XM | 1 |
| Zhang, DD | 1 |
| Aslanyan, S | 1 |
| Weir, CJ | 1 |
| Johnston, SC | 1 |
| Lees, KR | 1 |
| Fei, Z | 1 |
| Zhang, X | 1 |
| Bai, HM | 1 |
| Jiang, XF | 1 |
| Wang, XL | 1 |
| Kiewert, C | 1 |
| Kumar, V | 1 |
| Hildmann, O | 1 |
| Hartmann, J | 1 |
| Hillert, M | 1 |
| Klein, J | 1 |
| Witz, CA | 1 |
| Silverberg, KM | 1 |
| Burns, WN | 1 |
| Schenken, RS | 1 |
| Olive, DL | 1 |
| Beutler, JJ | 1 |
| Koomans, HA | 1 |
| Parramón, F | 1 |
| Fernández, JM | 1 |
| Hernández, C | 1 |
| Garcia, R | 1 |
| Ricart, W | 1 |
| Villalonga, A | 1 |
| Istre, O | 1 |
| Bjoennes, J | 1 |
| Naess, R | 1 |
| Hornbaek, K | 1 |
| Forman, A | 1 |
| Fujikawa, DG | 1 |
| Kim, JS | 1 |
| Daniels, AH | 1 |
| Alcaraz, AF | 1 |
| Sohn, TB | 1 |
| Ichai, C | 1 |
| Ciais, JF | 1 |
| Roussel, LJ | 1 |
| Levraut, J | 1 |
| Candito, M | 1 |
| Boileau, P | 1 |
| Grimaud, D | 1 |
| Colwell, CS | 1 |
| Levine, MS | 1 |
| Estevez, AY | 1 |
| O'Regan, MH | 1 |
| Song, D | 1 |
| Phillis, JW | 1 |
| Schwartz, ML | 1 |
| Sorensen, FW | 1 |
| Gregersen, M | 1 |
| Shimakura, A | 1 |
| Kamanaka, Y | 1 |
| Ikeda, Y | 1 |
| Kondo, K | 1 |
| Suzuki, Y | 1 |
| Umemura, K | 1 |
| Coraim, FI | 1 |
| Owen, A | 1 |
| Trubel, W | 1 |
| Kassal, H | 1 |
| Widhalm, K | 1 |
| Nakazawa, S | 3 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial of Lung Ultrasound-Guided Intraoperative Fluid Management Strategies: Assessing Their Impact on Post-operative Pulmonary Complications and Hemodynamics in Shoulder Arthroscopic Surgerys[NCT06104020] | 60 participants (Anticipated) | Interventional | 2023-11-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for glycine and Brain Edema
| Article | Year |
|---|---|
Complications associated with the absorption of hysteroscopic fluid media.
Topics: Absorption; Anaphylaxis; Blood Coagulation Disorders; Brain Edema; Dextrans; Diuretics; Female; Glyc | 1993 |
1 trial available for glycine and Brain Edema
| Article | Year |
|---|---|
Poststroke neurological improvement within 7 days is associated with subsequent deterioration.
Topics: Aged; Aged, 80 and over; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Cohort Studies; Double- | 2004 |
23 other studies available for glycine and Brain Edema
| Article | Year |
|---|---|
A hypothesis for mechanism for brain oedema due to glycine.
Topics: Animals; Brain Edema; Diffusion; Glycine; Humans; Hyponatremia; Hysteroscopy; Male; Models, Theoreti | 2017 |
Glycine confers neuroprotection through PTEN/AKT signal pathway in experimental intracerebral hemorrhage.
Topics: Animals; Benzimidazoles; Benzothiazoles; Brain Edema; Cell Death; Cerebral Hemorrhage; Disease Model | 2018 |
Activation of mGluR5 Attenuates Microglial Activation and Neuronal Apoptosis in Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Brain Edema; Caspase 3; Cerebral C | 2015 |
Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema.
Topics: Acute Disease; Angiopoietin-1; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Ce | 2010 |
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat | 2012 |
Pathological and toxicological findings in glyphosate-surfactant herbicide fatality: a case report.
Topics: Adult; Brain; Brain Edema; Chromatography, High Pressure Liquid; Esophagus; Female; Forensic Patholo | 2012 |
Activation of metabotropic glutamate receptor 5 reduces the secondary brain injury after traumatic brain injury in rats.
Topics: Animals; Brain Edema; Brain Injuries; Excitatory Amino Acid Agonists; Glycine; Male; Microglia; Nerv | 2013 |
Metabotropic glutamate receptor antagonists and agonists: potential neuroprotectors in diffuse brain injury.
Topics: Animals; Body Water; Brain; Brain Edema; Cell Death; Cyclopropanes; Diffuse Axonal Injury; Disease M | 2006 |
Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide.
Topics: Animals; Binding Sites; Binding, Competitive; Brain Edema; Brain Ischemia; Chlorides; Choline; Cyclo | 2008 |
Safety and transcervical endometrial resection.
Topics: Absorption; Brain Edema; Endometrium; Female; Glycine; Humans; Hyponatremia; Postoperative Complicat | 1995 |
Safety and transcervical endometrial resection.
Topics: Adult; Brain Edema; Endometrium; Female; Glycine; Humans; Hyponatremia; Menstrual Cycle; Postoperati | 1995 |
Postoperative cerebral oedema after transcervical endometrial resection and uterine irrigation with 1.5% glycine.
Topics: Absorption; Adult; Brain Edema; Endometrium; Female; Follow-Up Studies; Glycine; Humans; Hyponatremi | 1994 |
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons.
Topics: Amygdala; Animals; Aspartic Acid; Brain Edema; Extracellular Space; Glutamic Acid; Glutamine; Glycin | 1996 |
Intravascular absorption of glycine irrigating solution during shoulder arthroscopy: a case report and follow-up study.
Topics: Absorption; Adult; Aged; Arthroscopy; Brain Death; Brain Edema; Fatal Outcome; Female; Follow-Up Stu | 1996 |
Metabotropic glutamate receptor modulation of excitotoxicity in the neostriatum: role of calcium channels.
Topics: Animals; Barium; Brain Edema; Cadmium; Calcium Channel Blockers; Calcium Channels; Cycloleucine; Exc | 1999 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra | 1999 |
Distention fluid complication in hysteroscopic surgery.
Topics: Animals; Brain Edema; Female; Glycine; Humans; Hyponatremia; Hysteroscopy; Mannitol; Monitoring, Int | 1999 |
Rapid lethal intoxication caused by the herbicide glyphosate-trimesium (Touchdown).
Topics: Adult; Brain Edema; Child; Duodenum; Esophagus; Fatal Outcome; Female; Gastric Mucosa; Glycine; Glyp | 1999 |
Neutrophil elastase inhibition reduces cerebral ischemic damage in the middle cerebral artery occlusion.
Topics: Animals; Antilymphocyte Serum; Brain Edema; Brain Ischemia; Cell Count; Cerebral Cortex; Corpus Stri | 2000 |
Regulatory effect of neurotransmitter by hemofiltration in cardiogenic shock patients after open heart surgery.
Topics: Adolescent; Adult; Aged; Ammonia; Aspartic Acid; Brain Edema; Coronary Artery Bypass; Female; Glasgo | 1991 |
Biochemical studies of cerebral tissues in experimentally induced edema.
Topics: Adenosine Triphosphatases; Aminobutyrates; Animals; Brain Chemistry; Brain Edema; Carbon Isotopes; C | 1969 |
[Biochemical studies of cerebral edema--with special reference to the dynamic metabolism of proteins and nucleic acids].
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Brain Edema; Carbon Isotopes; Carboxy-Lyases; Cats; | 1971 |
RNA and protein synthesis in brain tissue during experimentally induced edema.
Topics: Animals; Brain Edema; Cerebral Cortex; Electric Stimulation; Freezing; Glycine; In Vitro Techniques; | 1968 |