glycine has been researched along with Brain Disorders in 44 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonketotic hyperglycinemia (NKH) or glycine encephalopathy is an autosomal recessive disorder of glycine metabolism resulting in an excessive accumulation of glycine in all body tissues, including the central nervous system." | 3.91 | Nonketotic Hyperglycinemia: Two Case Reports and Review. ( Al Futaisi, A; Al Murshidi, F; Al Thihli, K; Poothrikovil, RP, 2019) |
| "Elevated levels of glycine in the CSF have recently been documented in van der Knaap syndrome (diffuse leukoencephalopathy associated with cystic degeneration of the white matter)." | 3.71 | Demonstration of glycine peaks at 3.50 ppm in a patient with van der Knaap syndrome. ( Sener, RN, 2001) |
| "The term cerebral palsy is restricted to non-progressive disorders of motor function, already observed at an early age and due to cerebral lesions." | 2.37 | [Functional neurosurgery of cerebral palsy]. ( Alexandre, F; Angelini, L; Benezech, J; Broggi, G; Claverie, P; Deonna, T; Frerebeau, P; Lazorthes, Y; Siegfried, J; Verdie, JC, 1985) |
| "Several of these syndromes are associated with an encephalopathy that characteristically shows episodes of rapid neurological deterioration and the development of acute cerebral lesions." | 1.36 | Localized cerebral energy failure in DNA polymerase gamma-associated encephalopathy syndromes. ( Bindoff, LA; Engelsen, BE; Ersland, L; Moen, G; Mørk, SJ; Neckelmann, G; Tzoulis, C; Viscomi, C; Zeviani, M, 2010) |
| "Diffuse leukoencephalopathy associated with ocular malformations of the Axenfeld-Rieger type was observed in five individuals." | 1.34 | COL4A1 mutation in Axenfeld-Rieger anomaly with leukoencephalopathy and stroke. ( Arveiler, B; Bouchet, JP; Burgelin, I; Calvas, P; Coupry, I; Dousset, V; Goizet, C; Gorry, P; Lacombe, D; Menegon, P; Orgogozo, JM; Orignac, I; Sibon, I, 2007) |
| "Glycine encephalopathy is a rare autosomal recessive metabolic disease characterized by glycine accumulation in body fluids owing to a defect in the glycine cleavage system." | 1.33 | Two cases of glycine encephalopathy accompanied by pes equinovarus. ( Agildere, M; Aydemir, C; Bas, AY; Coskun, T; Demirel, N; Kalkanoglu, S; Zenciroglu, A, 2005) |
| "Early infantile epileptic encephalopathy (EIEE) with suppression burst activity in EEG (Ohtahara syndrome) is a rare type of epileptic encephalopathy in infancy and represents the earliest type of age-related symptomatic generalized epilepsy." | 1.30 | [Early infantile epileptic encephalopathy and glycine encephalopathy]. ( Carratalà, F; González de Dios, J; Izura, V; Moya, M; Pastore, C, 1997) |
| "Choline treatment did not change brain choline content, and was not associated with clinical or radiological improvement." | 1.30 | One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. ( Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH, 1998) |
| "This leukoencephalopathy has an autosomal-recessive mode of inheritance." | 1.30 | Increased cerebrospinal fluid glycine: a biochemical marker for a leukoencephalopathy with vanishing white matter. ( Gabreëls, FJ; Jaeken, J; Kure, S; van der Knaap, MS; van Raaij-Selten, B; Verhoeven, NM; Wevers, RA, 1999) |
| "Glycine is an inhibitory neurotransmitter, whereas glyoxylic acid and glycolic acid are considered as to be neurotoxic." | 1.29 | [Neurotoxic role of glycocolle and derivatives in transurethral resection of the prostate]. ( Auboyer, C; Dumont, A; Gilloz, A; Jospé, R; Levigne, F; Mahul, P; Molliex, S, 1993) |
| "Thiamine-deficient encephalopathy in the rat is characterized by ataxic gait, loss of righting reflex and curvature of the spine." | 1.26 | Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia. ( Barbeau, A; Butterworth, RF; Hamel, E; Landreville, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (36.36) | 18.7374 |
| 1990's | 11 (25.00) | 18.2507 |
| 2000's | 10 (22.73) | 29.6817 |
| 2010's | 4 (9.09) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Courtier, A | 1 |
| Potheret, D | 1 |
| Giannoni, P | 1 |
| Poothrikovil, RP | 1 |
| Al Thihli, K | 1 |
| Al Futaisi, A | 1 |
| Al Murshidi, F | 1 |
| Rakotomamonjy, J | 1 |
| Rylaarsdam, L | 1 |
| Guemez-Gamboa, A | 1 |
| Yokoyama, S | 1 |
| Sugisaki, T | 1 |
| Ryota, Y | 1 |
| Yoshiteru, S | 1 |
| Okayasu, H | 1 |
| Shioda, M | 1 |
| Suzuki, K | 1 |
| Yasui-Furukori, N | 1 |
| Shimoda, K | 1 |
| Habarou, F | 1 |
| Hamel, Y | 1 |
| Haack, TB | 1 |
| Feichtinger, RG | 1 |
| Lebigot, E | 1 |
| Marquardt, I | 1 |
| Busiah, K | 1 |
| Laroche, C | 1 |
| Madrange, M | 1 |
| Grisel, C | 1 |
| Pontoizeau, C | 1 |
| Eisermann, M | 1 |
| Boutron, A | 1 |
| Chrétien, D | 1 |
| Chadefaux-Vekemans, B | 1 |
| Barouki, R | 1 |
| Bole-Feysot, C | 1 |
| Nitschke, P | 1 |
| Goudin, N | 1 |
| Boddaert, N | 1 |
| Nemazanyy, I | 1 |
| Delahodde, A | 1 |
| Kölker, S | 1 |
| Rodenburg, RJ | 1 |
| Korenke, GC | 1 |
| Meitinger, T | 1 |
| Strom, TM | 1 |
| Prokisch, H | 1 |
| Rotig, A | 1 |
| Ottolenghi, C | 1 |
| Mayr, JA | 1 |
| de Lonlay, P | 1 |
| Amin, JB | 1 |
| Leng, X | 1 |
| Gochman, A | 1 |
| Zhou, HX | 1 |
| Wollmuth, LP | 1 |
| Tzoulis, C | 1 |
| Neckelmann, G | 1 |
| Mørk, SJ | 1 |
| Engelsen, BE | 1 |
| Viscomi, C | 1 |
| Moen, G | 1 |
| Ersland, L | 1 |
| Zeviani, M | 1 |
| Bindoff, LA | 1 |
| Toone, JR | 2 |
| Applegarth, DA | 2 |
| Kure, S | 2 |
| Coulter-Mackie, MB | 1 |
| Sazegar, P | 1 |
| Kojima, K | 1 |
| Ichinohe, A | 1 |
| Van der Knaap, MS | 2 |
| Laliberte, G | 1 |
| Debus, OM | 1 |
| Kosch, A | 1 |
| Sträter, R | 1 |
| Rossi, R | 1 |
| Nowak-Göttl, U | 1 |
| Nelson, TE | 1 |
| Netzeband, JG | 1 |
| Gruol, DL | 1 |
| Ward, MW | 1 |
| Kushnareva, Y | 1 |
| Greenwood, S | 1 |
| Connolly, CN | 1 |
| Zenciroglu, A | 1 |
| Demirel, N | 1 |
| Bas, AY | 1 |
| Aydemir, C | 1 |
| Agildere, M | 1 |
| Kalkanoglu, S | 1 |
| Coskun, T | 1 |
| Sibon, I | 1 |
| Coupry, I | 1 |
| Menegon, P | 1 |
| Bouchet, JP | 1 |
| Gorry, P | 1 |
| Burgelin, I | 1 |
| Calvas, P | 1 |
| Orignac, I | 1 |
| Dousset, V | 1 |
| Lacombe, D | 1 |
| Orgogozo, JM | 1 |
| Arveiler, B | 1 |
| Goizet, C | 1 |
| Aicardi, J | 2 |
| Roesch, RP | 1 |
| Stoelting, RK | 1 |
| Lingeman, JE | 1 |
| Kahnoski, RJ | 1 |
| Backes, DJ | 1 |
| Gephardt, SA | 1 |
| Mangar, D | 1 |
| Greene, JG | 1 |
| Greenamyre, JT | 1 |
| Boatell, ML | 1 |
| Bendahan, G | 1 |
| Mahy, N | 1 |
| Mahul, P | 1 |
| Molliex, S | 1 |
| Auboyer, C | 1 |
| Levigne, F | 1 |
| Jospé, R | 1 |
| Dumont, A | 1 |
| Gilloz, A | 1 |
| Olney, JW | 1 |
| González de Dios, J | 1 |
| Moya, M | 1 |
| Pastore, C | 1 |
| Izura, V | 1 |
| Carratalà, F | 1 |
| Van Hove, JL | 1 |
| Lazeyras, F | 1 |
| Zeisel, SH | 1 |
| Bottiglieri, T | 1 |
| Hyland, K | 1 |
| Charles, HC | 1 |
| Gray, L | 1 |
| Jaeken, J | 2 |
| Kahler, SG | 1 |
| Vion-Dury, J | 1 |
| Salvan, AM | 1 |
| Confort-Gouny, S | 1 |
| Cozzone, PJ | 1 |
| Wevers, RA | 1 |
| Gabreëls, FJ | 1 |
| Verhoeven, NM | 1 |
| van Raaij-Selten, B | 1 |
| Henrich-Noack, P | 1 |
| Flor, PJ | 1 |
| Sabelhaus, CF | 1 |
| Prass, K | 1 |
| Dirnagl, U | 1 |
| Gasparini, F | 1 |
| Sauter, A | 1 |
| Rudin, M | 1 |
| Reymann, KG | 1 |
| Sener, RN | 1 |
| Butterworth, RF | 1 |
| Hamel, E | 1 |
| Landreville, F | 1 |
| Barbeau, A | 1 |
| Melançon, SB | 1 |
| Dallaire, L | 1 |
| Vincelette, P | 1 |
| Potier, M | 1 |
| Geoffroy, G | 1 |
| Dalla Bernardina, B | 1 |
| Goutières, F | 1 |
| Plouin, P | 1 |
| Ch'ien, LT | 1 |
| Chance, P | 1 |
| Arneson, D | 1 |
| Wilroy, RS | 1 |
| Ranu, GS | 1 |
| McBride, WJ | 1 |
| Aprison, MH | 1 |
| Kusano, K | 1 |
| Eyskens, FJ | 1 |
| Van Doorn, JW | 1 |
| Mariën, P | 1 |
| McDonald, JW | 1 |
| Johnston, MV | 1 |
| Siegfried, J | 1 |
| Lazorthes, Y | 1 |
| Broggi, G | 1 |
| Claverie, P | 1 |
| Deonna, T | 1 |
| Frerebeau, P | 1 |
| Verdie, JC | 1 |
| Alexandre, F | 1 |
| Angelini, L | 1 |
| Benezech, J | 1 |
| Simler, S | 1 |
| Owsianowski, N | 1 |
| Randrianarisoa, H | 1 |
| Ledig, M | 1 |
| Mandel, P | 1 |
| Krieger, I | 1 |
| Hart, ZH | 1 |
| Vortel, V | 1 |
| Peychl, L | 1 |
| Ghisolfi, J | 1 |
| Augier, D | 1 |
| Fabre, J | 1 |
| Delsol, G | 1 |
| Régnier, C | 1 |
| Szelenyi, I | 1 |
| Farkas, I | 1 |
| Desi, I | 1 |
| Nemesánszky, E | 1 |
| Hooft, C | 1 |
| Van Nevel, C | 1 |
| De Schaepdryver, AF | 1 |
| Kolkmann, W | 1 |
| Visakorpi, JK | 1 |
| Donner, M | 1 |
| Norio, R | 1 |
4 reviews available for glycine and Brain Disorders
| Article | Year |
|---|---|
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk.
Topics: Amino Acids, Diamino; Brain Diseases; Cyanobacteria; Glycine; Humans; Isomerism; Neurotoxins | 2022 |
[Myoclonias as a manifestation of degenerative disorders of the central nervous system in childhood].
Topics: Adolescent; Age Factors; Brain Diseases; Cerebellar Diseases; Ceroid; Child; Child, Preschool; Diagn | 1982 |
Role of excitotoxins in developmental neuropathology.
Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain Diseases; Brain Ischemia; Cloning, Molecu | 1993 |
[Functional neurosurgery of cerebral palsy].
Topics: Adolescent; Adult; Animals; Baclofen; Benzodiazepines; Brain; Brain Diseases; Cerebellar Cortex; Cer | 1985 |
40 other studies available for glycine and Brain Disorders
| Article | Year |
|---|---|
Nonketotic Hyperglycinemia: Two Case Reports and Review.
Topics: Agenesis of Corpus Callosum; Apnea; Brain; Brain Diseases; Electroencephalography; Fatal Outcome; Fe | 2019 |
PYRC2-Related Hypomyelinating Leukodystrophy: More to This Than Meets the Eye.
Topics: Brain Diseases; Glycine; Humans; Pyrroline Carboxylate Reductases; Ubiquitin-Protein Ligases | 2020 |
Transient glyphosate encephalopathy due to a suicide attempt.
Topics: Brain Diseases; Glycine; Glyphosate; Herbicides; Humans; Male; Suicide, Attempted | 2021 |
Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy.
Topics: Acyltransferases; Amino Acids; Atrophy; Brain; Brain Diseases; Brain Mapping; Cells, Cultured; Energ | 2017 |
A conserved glycine harboring disease-associated mutations permits NMDA receptor slow deactivation and high Ca
Topics: Animals; Brain Diseases; Calcium; Cell Membrane Permeability; Child; Child, Preschool; Developmental | 2018 |
Localized cerebral energy failure in DNA polymerase gamma-associated encephalopathy syndromes.
Topics: Arginine; Brain; Brain Diseases; Cerebellum; Cysteine; Diffuse Cerebral Sclerosis of Schilder; Diffu | 2010 |
Novel mutations in the P-protein (glycine decarboxylase) gene in patients with glycine encephalopathy (non-ketotic hyperglycinemia).
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Oxidoreductases; Base Sequence; Brain Diseases; DNA | 2002 |
Forget About "van der Knaap syndrome," forget about glycine.
Topics: Brain; Brain Diseases; Diagnosis, Differential; Glycine; Humans; Magnetic Resonance Spectroscopy; Sy | 2003 |
Gene Symbol: GLDC. Disease: NKH glycine encephalopathy.
Topics: Amino Acid Oxidoreductases; Amino Acid Substitution; Brain Diseases; Codon; Codon, Nonsense; Glycine | 2003 |
The factor V G1691A mutation is a risk for porencephaly: A case-control study.
Topics: Alanine; Brain Diseases; Case-Control Studies; Chi-Square Distribution; Child; Factor V; Female; Gen | 2004 |
Chronic interleukin-6 exposure alters metabotropic glutamate receptor-activated calcium signalling in cerebellar Purkinje neurons.
Topics: Adenosine Triphosphatases; Animals; Brain Diseases; Calcium; Calcium Channel Blockers; Calcium Signa | 2004 |
Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons.
Topics: Age Factors; Alamethicin; Analysis of Variance; Animals; Animals, Newborn; Brain Diseases; Calcium; | 2005 |
Two cases of glycine encephalopathy accompanied by pes equinovarus.
Topics: Brain; Brain Diseases; Clubfoot; Glycine; Humans; Infant, Newborn; Magnetic Resonance Imaging; Male | 2005 |
COL4A1 mutation in Axenfeld-Rieger anomaly with leukoencephalopathy and stroke.
Topics: Adult; Anterior Eye Segment; Aspartic Acid; Autoantigens; Brain Diseases; Child; Collagen Type IV; E | 2007 |
Ammonia toxicity resulting from glycine absorption during a transurethral resection of the prostate.
Topics: Absorption; Aged; Ammonia; Brain Diseases; Glycine; Humans; Hyponatremia; Male; Postoperative Period | 1983 |
Hyponatremic encephalopathy after endometrial ablation.
Topics: Brain Diseases; Dextrans; Endometrium; Female; Glycine; Humans; Hyponatremia; Postoperative Complica | 1994 |
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body Temperature; Brain Diseases; | 1995 |
Time-related cortical amino acid changes after basal forebrain lesion: a microdialysis study.
Topics: Alzheimer Disease; Amino Acids; Animals; Brain Diseases; Cerebral Cortex; Chromatography, High Press | 1995 |
[Neurotoxic role of glycocolle and derivatives in transurethral resection of the prostate].
Topics: Aged; Anesthesia, Spinal; Brain Diseases; Coma; Glycine; Humans; Hyponatremia; Male; Prostatectomy; | 1993 |
[Early infantile epileptic encephalopathy and glycine encephalopathy].
Topics: Brain Diseases; Electroencephalography; Epilepsy, Generalized; Fatal Outcome; Female; Glycine; Human | 1997 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; | 1998 |
Atlas of brain proton magnetic resonance spectra. Part II: Inherited metabolic encephalopathies.
Topics: Adipates; Adult; Anatomy, Artistic; Argininosuccinic Acid; Argininosuccinic Aciduria; Brain; Brain D | 1998 |
Increased cerebrospinal fluid glycine: a biochemical marker for a leukoencephalopathy with vanishing white matter.
Topics: Adolescent; Adult; Biomarkers; Brain; Brain Diseases; Child; Child, Preschool; Excitatory Amino Acid | 1999 |
Distinct influence of the group III metabotropic glutamate receptor agonist (R,S)-4-phosphonophenylglycine [(R,S)-PPG] on different forms of neuronal damage.
Topics: Action Potentials; Animals; Brain Diseases; Brain Ischemia; Cell Hypoxia; Corpus Striatum; Cytoprote | 2000 |
Demonstration of glycine peaks at 3.50 ppm in a patient with van der Knaap syndrome.
Topics: Brain; Brain Diseases; Cysts; Glycine; Humans; Infant; Magnetic Resonance Spectroscopy; Male | 2001 |
Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Friedreich Ataxia; gamma-Aminobutyric Ac | 1979 |
Early treatment of severe infantile glycine encephalopathy (nonketotic hyperglycinemia) with strychnine and sodium benzoate.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoates; Brain Diseases; Child, Preschool; Electroencephalog | 1979 |
Glycine encephalopathy.
Topics: Amino Acid Metabolism, Inborn Errors; Brain; Brain Diseases; Electroencephalography; Female; Glycine | 1979 |
Glycine encephalopathy.
Topics: Brain Diseases; Female; Glycine; Humans; Hyperglycemia; Infant; Strychnine | 1978 |
Contents of several amino acids in the cerebellum, brain stem and cerebrum of the 'staggerer', 'weaver' and 'nervous' neurologically mutant mice.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Brain Stem; Cerebellum; Disease | 1976 |
Neurologic sequelae in transient nonketotic hyperglycinemia of the neonate.
Topics: Amino Acid Metabolism, Inborn Errors; Brain Diseases; Glycine; Humans; Infant, Newborn; Male | 1992 |
Pharmacology of N-methyl-D-aspartate-induced brain injury in an in vivo perinatal rat model.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain Diseases; Female; Glycine; Male; N-Methylaspartate | 1990 |
Biosynthesis of free amino acids in the brain of Jimpy mice.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Brain; Brain Diseases; Carbon Radioisoto | 1974 |
Valine-sensitive nonketotic hyperglycinemia. Case report.
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Benzoates; Brain Diseases; Brain Stem; C | 1974 |
[2 cases of acquired latent focal toxoplasmosis of the brain in a cytostatic and corticosteroid treated neoplastic disease].
Topics: Autopsy; Brain; Brain Diseases; Busulfan; Female; Focal Infection; Glycine; Humans; Leukemia, Myeloi | 1970 |
[Familial encephalopathy, imino-glycinuria, hydroxyprolinemia].
Topics: Amino Acid Metabolism, Inborn Errors; Brain Diseases; Glomerular Filtration Rate; Glycine; Humans; H | 1972 |
[Effect of magnesium orotate glycinate on the brain electric activity after experimental ammonia poisoning].
Topics: Ammonia; Animals; Brain Diseases; Chemical and Drug Induced Liver Injury; Electroencephalography; Fe | 1971 |
Hyperuricosuric encephalopathy without hyperuricaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Body Weight; Brain Diseases; Carbon Isotopes; Child, Preschool | 1968 |
[Findings concerning the glia in diffuse and focally disseminated types of infantile spongy neurodystrophy].
Topics: Amino Acid Metabolism, Inborn Errors; Brain Diseases; Demyelinating Diseases; Glycine; Humans; Infan | 1968 |
Hyperglycinuria with severe neurological manifestations.
Topics: Amino Acids; Brain Diseases; Brain Stem; Chromatography; Diagnosis, Differential; Electroencephalogr | 1965 |