Page last updated: 2024-10-18

glycine and Biliary Cirrhosis

glycine has been researched along with Biliary Cirrhosis in 9 studies

Research Excerpts

ExcerptRelevanceReference
"Ursodeoxycholic acid (UDCA) exerts anticholestatic, antifibrotic and antiproliferative effects in primary biliary cirrhosis (PBC) via mechanisms not yet fully understood."9.16Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health. ( Bastiaansen, BA; Beuers, U; Dilger, K; Hohenester, S; Rust, C; Schaap, FG; Winkler-Budenhofer, U, 2012)
"We have applied a specific and accurate high pressure liquid chromatographic technique to determine fasting serum glycine and taurine conjugates of individual bile acids in patients with primary biliary cirrhosis before and during ursodeoxycholic acid therapy."7.67Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic treatment. ( Chazouilleres, O; Chretien, Y; Gherardt, MF; Labbe, D; Myara, A; Poupon, R; Trivin, F, 1989)
"Ursodeoxycholic acid (UDCA) exerts anticholestatic, antifibrotic and antiproliferative effects in primary biliary cirrhosis (PBC) via mechanisms not yet fully understood."5.16Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health. ( Bastiaansen, BA; Beuers, U; Dilger, K; Hohenester, S; Rust, C; Schaap, FG; Winkler-Budenhofer, U, 2012)
"The concentration of total bile acids, taurine and glycine conjugates of primary bile acids was elevated in both patients with primary biliary cirrhosis and primary sclerosing cholangitis when compared to non-cholestatic donors."3.78Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: a pilot study. ( Barbier, O; Białek, A; Caron, P; Heathcote, J; Milkiewicz, P; Straka, RJ; Trottier, J, 2012)
"We have applied a specific and accurate high pressure liquid chromatographic technique to determine fasting serum glycine and taurine conjugates of individual bile acids in patients with primary biliary cirrhosis before and during ursodeoxycholic acid therapy."3.67Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic treatment. ( Chazouilleres, O; Chretien, Y; Gherardt, MF; Labbe, D; Myara, A; Poupon, R; Trivin, F, 1989)
"While drug-related biliary cirrhosis is rarely fatal, this case presented an unusually rapid course of fatal biliary cirrhosis."1.29A case of drug-induced ductopenia resulting in fatal biliary cirrhosis. ( Ishii, M; Miura, M; Miyazaki, Y; Takahashi, T; Toyota, T; Ueno, Y; Yamamoto, T, 1993)
"The bilirubin clearance was impaired to 30-50% of the normal value in most cases of hepatobiliary disease and also in primary haemolysis."1.28The origins and kinetics of bilirubin in dogs with hepatobiliary and haemolytic diseases. ( Fevery, J; Rothuizen, J; van den Brom, WE, 1992)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Liu, D2
Li, G1
Shi, W1
Wang, H1
Zhang, Q1
Shen, M1
Huang, X1
Lin, H1
Pastor, CM1
Trottier, J1
Białek, A1
Caron, P1
Straka, RJ1
Heathcote, J1
Milkiewicz, P1
Barbier, O1
Dilger, K1
Hohenester, S1
Winkler-Budenhofer, U1
Bastiaansen, BA1
Schaap, FG1
Rust, C1
Beuers, U1
Ito, S1
Xu, Y1
Keyser, AJ1
Peters, RL1
Ishii, M1
Miyazaki, Y1
Yamamoto, T1
Miura, M1
Ueno, Y1
Takahashi, T1
Toyota, T1
Rothuizen, J1
van den Brom, WE1
Fevery, J1
Chretien, Y1
Poupon, R1
Gherardt, MF1
Chazouilleres, O1
Labbe, D1
Myara, A1
Trivin, F1
Murphy, GM1
Ross, A1
Billing, BH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00529009]Phase 10 participants Interventional2007-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for glycine and Biliary Cirrhosis

ArticleYear
Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health.
    Journal of hepatology, 2012, Volume: 57, Issue:1

    Topics: Adult; Bile Acids and Salts; Biliary Tract; Carrier Proteins; Cholagogues and Choleretics; Cholestas

2012

Other Studies

8 other studies available for glycine and Biliary Cirrhosis

ArticleYear
Quantitative Detection of 15 Serum Bile Acid Metabolic Products by LC/MS/MS in the Diagnosis of Primary Biliary Cholangitis.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:3

    Topics: Bile Acids and Salts; Biomarkers; Chromatography, Liquid; Glycine; Humans; Liver Cirrhosis, Biliary;

2023
Isolated Perfused Rat Livers to Quantify the Pharmacokinetics and Concentrations of Gd-BOPTA.
    Contrast media & molecular imaging, 2018, Volume: 2018

    Topics: Aniline Compounds; Animals; ATP-Binding Cassette Transporters; Bile Canaliculi; Biological Transport

2018
Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: a pilot study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:4

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Cholangit

2012
Histochemical demonstration of guanase in human liver with guanine in bicine buffer as substrate.
    The Histochemical journal, 1984, Volume: 16, Issue:5

    Topics: Adult; Aminohydrolases; Buffers; Female; Glycine; Guanine; Guanine Deaminase; Histocytochemistry; Hu

1984
A case of drug-induced ductopenia resulting in fatal biliary cirrhosis.
    Liver, 1993, Volume: 13, Issue:4

    Topics: Bile Duct Diseases; Bile Ducts, Intrahepatic; Cysteine; Drug Combinations; Female; Glycine; Glycyrrh

1993
The origins and kinetics of bilirubin in dogs with hepatobiliary and haemolytic diseases.
    Journal of hepatology, 1992, Volume: 15, Issue:1-2

    Topics: Anemia, Hemolytic; Animals; Bilirubin; Carbon Radioisotopes; Dogs; Erythrocytes; Female; Glycine; He

1992
Bile acid glycine and taurine conjugates in serum of patients with primary biliary cirrhosis: effect of ursodeoxycholic treatment.
    Gut, 1989, Volume: 30, Issue:8

    Topics: Bile Acids and Salts; Chromatography, High Pressure Liquid; Deoxycholic Acid; Female; Glycine; Human

1989
Serum bile acids in primary biliary cirrhosis.
    Gut, 1972, Volume: 13, Issue:3

    Topics: Bile Acids and Salts; Cholestasis; Cholestyramine Resin; Glycine; Humans; Hydroxylation; Liver Cirrh

1972