glycine has been researched along with Autistic Disorder in 23 studies
Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The wider significance of such conversions is discussed with similar metabolism of tryptophan and subsequent glycine conjugation potentially explaining the origin of trans-indolylacryloylglycine, a postulated marker for autism." | 7.78 | Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism. ( Clayton, TA, 2012) |
| "To test whether the presence of indolyl-3-acryloylglycine (IAG) is associated with autism, we analyzed urine from population-based, blinded cohorts." | 7.73 | Is the presence of urinary indolyl-3-acryloylglycine associated with autism spectrum disorder? ( Brzozowski, AM; Calvert, E; Farnworth, H; Goodall, DM; Holbrook, I; Imrie, G; Jordan, J; Kelly, A; Miles, J; Smith, R; Town, J; Wright, B, 2005) |
| "Two toxins most implicated in the U." | 5.48 | Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). ( Good, P, 2018) |
| "In mice, neuroligin-4 deletions caused autism-related behavioral impairments and subtle changes in synaptic transmission, and neuroligin-4 was found, at least in part, at glycinergic synapses." | 5.48 | Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses. ( Brose, N; Gokce, O; Hale, WD; Südhof, TC; Zhang, B, 2018) |
| "Autism is a heterogeneous pervasive developmental disorder with a poorly defined aetiology and pathophysiology." | 5.32 | Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. ( Anderson, R; Bull, G; Groundwater, PW; Lees, G; Lough, JW; Shattock, P; Whiteley, P, 2003) |
| " Diagnosis of autism was based on DSM-V criteria and the severity degree was measured by ABC-C checklists at base line and after 8 weeks of treatment with risperidone." | 3.85 | DRD3 Ser9Gly Polymorphism and Its Influence on Risperidone Response in Autistic Children. ( Firouzabadi, N; Nazariat, A; Zomorrodian, K, 2017) |
| " The wider significance of such conversions is discussed with similar metabolism of tryptophan and subsequent glycine conjugation potentially explaining the origin of trans-indolylacryloylglycine, a postulated marker for autism." | 3.78 | Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism. ( Clayton, TA, 2012) |
| "We determined creatine/creatinine ratio in urine samples from 1600 unrelated male patients with mental retardation and/or autism." | 3.74 | Creatine transporter deficiency: prevalence among patients with mental retardation and pitfalls in metabolite screening. ( Arias, A; Artuch, R; Briones, P; Campistol, J; Corbella, M; Fons, C; García-Villoria, J; Ormazabal, A; Pàmpols, T; Pineda, M; Poo, P; Ribes, A; Salomons, GS; Sempere, A; Vilaseca, MA, 2007) |
| "To test whether the presence of indolyl-3-acryloylglycine (IAG) is associated with autism, we analyzed urine from population-based, blinded cohorts." | 3.73 | Is the presence of urinary indolyl-3-acryloylglycine associated with autism spectrum disorder? ( Brzozowski, AM; Calvert, E; Farnworth, H; Goodall, DM; Holbrook, I; Imrie, G; Jordan, J; Kelly, A; Miles, J; Smith, R; Town, J; Wright, B, 2005) |
| "Two toxins most implicated in the U." | 1.48 | Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). ( Good, P, 2018) |
| "In mice, neuroligin-4 deletions caused autism-related behavioral impairments and subtle changes in synaptic transmission, and neuroligin-4 was found, at least in part, at glycinergic synapses." | 1.48 | Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses. ( Brose, N; Gokce, O; Hale, WD; Südhof, TC; Zhang, B, 2018) |
| "Autism is a spectrum of neurodevelopmental disorders with a primarily genetic etiology exhibiting deficits in (1) development of language and (2) social relationships and (3) patterns of repetitive, restricted behaviors or interests and resistance to change." | 1.33 | Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors. ( Blakely, RD; Delahanty, RJ; Folstein, SE; Han, Q; Jiang, L; Li, C; McCauley, JL; Prasad, HC; Sutcliffe, JS, 2005) |
| "Autism is a heterogeneous pervasive developmental disorder with a poorly defined aetiology and pathophysiology." | 1.32 | Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders. ( Anderson, R; Bull, G; Groundwater, PW; Lees, G; Lough, JW; Shattock, P; Whiteley, P, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Pu, Y | 1 |
| Yang, J | 1 |
| Chang, L | 1 |
| Qu, Y | 1 |
| Wang, S | 1 |
| Zhang, K | 1 |
| Xiong, Z | 1 |
| Zhang, J | 1 |
| Tan, Y | 1 |
| Wang, X | 1 |
| Fujita, Y | 1 |
| Ishima, T | 1 |
| Wang, D | 1 |
| Hwang, SH | 1 |
| Hammock, BD | 2 |
| Hashimoto, K | 2 |
| Reeves, W | 1 |
| Dunn, SE | 1 |
| Firouzabadi, N | 1 |
| Nazariat, A | 1 |
| Zomorrodian, K | 1 |
| Good, P | 1 |
| Sato, K | 1 |
| Zhang, B | 1 |
| Gokce, O | 1 |
| Hale, WD | 1 |
| Brose, N | 1 |
| Südhof, TC | 1 |
| Pilorge, M | 1 |
| Fassier, C | 1 |
| Le Corronc, H | 1 |
| Potey, A | 1 |
| Bai, J | 1 |
| De Gois, S | 1 |
| Delaby, E | 1 |
| Assouline, B | 1 |
| Guinchat, V | 1 |
| Devillard, F | 1 |
| Delorme, R | 1 |
| Nygren, G | 1 |
| Råstam, M | 1 |
| Meier, JC | 1 |
| Otani, S | 1 |
| Cheval, H | 1 |
| James, VM | 1 |
| Topf, M | 1 |
| Dear, TN | 1 |
| Gillberg, C | 1 |
| Leboyer, M | 1 |
| Giros, B | 1 |
| Gautron, S | 1 |
| Hazan, J | 1 |
| Harvey, RJ | 1 |
| Legendre, P | 1 |
| Betancur, C | 1 |
| Wang, L | 1 |
| Angley, MT | 1 |
| Gerber, JP | 1 |
| Young, RL | 1 |
| Abarno, DV | 1 |
| McKinnon, RA | 1 |
| Sorich, MJ | 1 |
| Ghanizadeh, A | 1 |
| Clayton, TA | 1 |
| Lees, HJ | 1 |
| Swann, JR | 1 |
| Wilson, ID | 1 |
| Nicholson, JK | 1 |
| Holmes, E | 1 |
| Bull, G | 1 |
| Shattock, P | 1 |
| Whiteley, P | 1 |
| Anderson, R | 1 |
| Groundwater, PW | 2 |
| Lough, JW | 1 |
| Lees, G | 1 |
| Conciatori, M | 1 |
| Stodgell, CJ | 1 |
| Hyman, SL | 1 |
| O'Bara, M | 1 |
| Militerni, R | 1 |
| Bravaccio, C | 1 |
| Trillo, S | 1 |
| Montecchi, F | 1 |
| Schneider, C | 1 |
| Melmed, R | 1 |
| Elia, M | 1 |
| Crawford, L | 1 |
| Spence, SJ | 1 |
| Muscarella, L | 1 |
| Guarnieri, V | 1 |
| D'Agruma, L | 1 |
| Quattrone, A | 1 |
| Zelante, L | 1 |
| Rabinowitz, D | 1 |
| Pascucci, T | 1 |
| Puglisi-Allegra, S | 1 |
| Reichelt, KL | 1 |
| Rodier, PM | 1 |
| Persico, AM | 1 |
| Wright, B | 1 |
| Brzozowski, AM | 1 |
| Calvert, E | 1 |
| Farnworth, H | 1 |
| Goodall, DM | 1 |
| Holbrook, I | 1 |
| Imrie, G | 1 |
| Jordan, J | 1 |
| Kelly, A | 1 |
| Miles, J | 1 |
| Smith, R | 1 |
| Town, J | 1 |
| Sutcliffe, JS | 1 |
| Delahanty, RJ | 1 |
| Prasad, HC | 1 |
| McCauley, JL | 1 |
| Han, Q | 1 |
| Jiang, L | 1 |
| Li, C | 1 |
| Folstein, SE | 1 |
| Blakely, RD | 1 |
| Coutinho, AM | 1 |
| Oliveira, G | 1 |
| Katz, C | 1 |
| Feng, J | 1 |
| Yan, J | 1 |
| Yang, C | 1 |
| Marques, C | 1 |
| Ataíde, A | 1 |
| Miguel, TS | 1 |
| Borges, L | 1 |
| Almeida, J | 1 |
| Correia, C | 1 |
| Currais, A | 1 |
| Bento, C | 1 |
| Mota-Vieira, L | 1 |
| Temudo, T | 1 |
| Santos, M | 1 |
| Maciel, P | 1 |
| Sommer, SS | 1 |
| Vicente, AM | 1 |
| Arias, A | 1 |
| Corbella, M | 1 |
| Fons, C | 1 |
| Sempere, A | 1 |
| García-Villoria, J | 1 |
| Ormazabal, A | 1 |
| Poo, P | 1 |
| Pineda, M | 1 |
| Vilaseca, MA | 1 |
| Campistol, J | 1 |
| Briones, P | 1 |
| Pàmpols, T | 1 |
| Salomons, GS | 1 |
| Ribes, A | 1 |
| Artuch, R | 1 |
| Deutsch, SI | 1 |
| Stanley, M | 1 |
| Peselow, ED | 1 |
| Banay-Schwartz, M | 1 |
| Khan, SG | 1 |
| Levy, HL | 1 |
| Legerski, R | 1 |
| Quackenbush, E | 1 |
| Reardon, JT | 1 |
| Emmert, S | 1 |
| Sancar, A | 1 |
| Li, L | 1 |
| Schneider, TD | 1 |
| Cleaver, JE | 1 |
| Kraemer, KH | 1 |
| Anderson, RJ | 1 |
| Bendell, DJ | 1 |
| Garnett, I | 1 |
| Lough, WJ | 1 |
| Mills, MJ | 1 |
| Savery, D | 1 |
| Shattock, PE | 1 |
| Schlange, H | 1 |
| Von Berg, W | 1 |
| Nyhan, WL | 1 |
| James, JA | 1 |
| Teberg, AJ | 1 |
| Sweetman, L | 1 |
| Nelson, LG | 1 |
2 reviews available for glycine and Autistic Disorder
| Article | Year |
|---|---|
Hippurate: the natural history of a mammalian-microbial cometabolite.
Topics: Age Factors; Animals; Atherosclerosis; Autistic Disorder; Benzoic Acid; Diabetes Mellitus; Diet; Fem | 2013 |
Glycine: a possible role in lithium's action and affective illness.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Autistic Disorder; Bipolar Disorder; Brain Chemistry; | 1983 |
21 other studies available for glycine and Autistic Disorder
| Article | Year |
|---|---|
Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase.
Topics: Animals; Autistic Disorder; Behavior, Animal; Brain Chemistry; Disease Models, Animal; Epoxide Hydro | 2020 |
Reply to Reeves and Dunn: Risk for autism in offspring after maternal glyphosate exposure.
Topics: Autistic Disorder; Epoxide Hydrolases; Female; Glycine; Glyphosate; Humans; Maternal Exposure | 2021 |
Additional observations regarding glyphosate-based herbicides and developmental toxicity.
Topics: Autistic Disorder; Epoxide Hydrolases; Female; Glycine; Glyphosate; Herbicides; Humans | 2021 |
DRD3 Ser9Gly Polymorphism and Its Influence on Risperidone Response in Autistic Children.
Topics: Adolescent; Alleles; Autistic Disorder; Child; Child, Preschool; Female; Genotype; Glycine; Humans; | 2017 |
Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup).
Topics: Acetaminophen; Amoxicillin-Potassium Clavulanate Combination; Androgens; Aromatase; Aromatase Inhibi | 2018 |
Why is vitamin B6 effective in alleviating the symptoms of autism?
Topics: Autistic Disorder; Dopamine; gamma-Aminobutyric Acid; Glycine; Histamine; Humans; Models, Neurologic | 2018 |
Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
Topics: Animals; Autistic Disorder; Brain Stem; Cell Adhesion Molecules, Neuronal; Excitatory Postsynaptic P | 2018 |
Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism.
Topics: Adolescent; Adult; Animals; Autism Spectrum Disorder; Autistic Disorder; Child; Child, Preschool; Gl | 2016 |
Is urinary indolyl-3-acryloylglycine a biomarker for autism with gastrointestinal symptoms?
Topics: Autistic Disorder; Biomarkers; Child; Child Development Disorders, Pervasive; Creatinine; Female; Ga | 2009 |
Targeting of glycine site on NMDA receptor as a possible new strategy for autism treatment.
Topics: Autistic Disorder; Glycine; Humans; Receptors, N-Methyl-D-Aspartate | 2011 |
Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism.
Topics: Animals; Autistic Disorder; Bacterial Proteins; Biomarkers; Chlorogenic Acid; Clostridium; Disease M | 2012 |
Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders.
Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Biological Assay; Child; Child, Preschool; Chroma | 2003 |
Association between the HOXA1 A218G polymorphism and increased head circumference in patients with autism.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Americas; Asperger Syndrome; Autistic Disorder; | 2004 |
Is the presence of urinary indolyl-3-acryloylglycine associated with autism spectrum disorder?
Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Cohort Studies; Diagnosis, Differential; Edu | 2005 |
Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors.
Topics: Alanine; Alleles; Autistic Disorder; Blood Platelets; Chromosomes, Human, Pair 17; Compulsive Behavi | 2005 |
MECP2 coding sequence and 3'UTR variation in 172 unrelated autistic patients.
Topics: 3' Untranslated Regions; Adolescent; Alanine; Autistic Disorder; Case-Control Studies; Child; Child, | 2007 |
Creatine transporter deficiency: prevalence among patients with mental retardation and pitfalls in metabolite screening.
Topics: Autistic Disorder; Child; Child, Preschool; Creatine; Creatinine; Glycine; Humans; Infant; Intellect | 2007 |
Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia.
Topics: Alternative Splicing; Autistic Disorder; Blotting, Northern; Child, Preschool; Chromosomes, Human, P | 1998 |
Identification of indolyl-3-acryloylglycine in the urine of people with autism.
Topics: Autistic Disorder; Chromatography, High Pressure Liquid; Glycine; Humans; Magnetic Resonance Spectro | 2002 |
[Autism in childhood--a metabolic disorder?].
Topics: Autistic Disorder; Child; Chromatography, Thin Layer; Glycine; Humans; Metabolic Diseases; Schizophr | 1967 |
A new disorder of purine metabolism with behavioral manifestations.
Topics: Adenine; Allopurinol; Autistic Disorder; Carbon Isotopes; Child Behavior Disorders; Child, Preschool | 1969 |