glycine has been researched along with Asthma, Bronchial in 36 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighteen patients with mild-to-moderate persistent asthma receiving inhaled corticosteroid who expressed the homozygous glycine-16 genotype were randomized to completion (mean [SEM] age, 35." | 9.09 | Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism. ( Aziz, I; Dempsey, OJ; Lipworth, BJ, 2000) |
| "In the United Kingdom, about 40% of patients with asthma are homozygous for the glycine-16 beta(2)-adrenoceptor polymorphism, which predisposes them to agonist-induced down-regulation and desensitization of the beta(2)-adrenoceptor." | 9.09 | Effects of adding a leukotriene antagonist or a long-acting beta(2)-agonist in asthmatic patients with the glycine-16 beta(2)-adrenoceptor genotype. ( Aziz, I; Dempsey, OJ; Lipworth, BJ; Wilson, AM, 2000) |
| "The patient's bronchial asthma attack was ascribed to SNMC." | 5.30 | [Bronchial asthma due to Stronger Neo-Minophagen C]. ( Abe, T; Fujimura, M; Matsuda, T; Nakatsumi, Y; Nomura, G, 1998) |
| "Retrospective pharmacogenetic studies have questioned whether patients with asthma who are arginine homozygous at the beta(2-)adrenergic receptor (position 16) should use long-acting beta-agonists." | 5.14 | Beta2-receptor polymorphisms in patients receiving salmeterol with or without fluticasone propionate. ( Anderson, WH; Bleecker, ER; Corren, J; Emmett, AH; Kraft, M; Meyers, DA; Nelson, HS; Ortega, HG; Yancey, SW, 2010) |
| "Eighteen patients with mild-to-moderate persistent asthma receiving inhaled corticosteroid who expressed the homozygous glycine-16 genotype were randomized to completion (mean [SEM] age, 35." | 5.09 | Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism. ( Aziz, I; Dempsey, OJ; Lipworth, BJ, 2000) |
| "In the United Kingdom, about 40% of patients with asthma are homozygous for the glycine-16 beta(2)-adrenoceptor polymorphism, which predisposes them to agonist-induced down-regulation and desensitization of the beta(2)-adrenoceptor." | 5.09 | Effects of adding a leukotriene antagonist or a long-acting beta(2)-agonist in asthmatic patients with the glycine-16 beta(2)-adrenoceptor genotype. ( Aziz, I; Dempsey, OJ; Lipworth, BJ; Wilson, AM, 2000) |
| " Despite similar clinical asthma scores on hospital admission, the children with the Gly/Gly genotype had significantly shorter hospital ICU length of stay and duration of continuously nebulized albuterol therapy and were significantly less likely to require IV beta(2)-AR therapy than those with Arg/Arg or Arg/Gly genotypes." | 3.75 | Beta2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations. ( Carroll, CL; Schramm, CM; Stoltz, P; Zucker, AR, 2009) |
| "To determine whether genetic polymorphisms of the beta2-adrenergic receptor gene affect the relationship between albuterol (INN, salbutamol) plasma concentrations and the forced expiratory volume in 1 second (FEV1) in subjects with moderate asthma." | 3.70 | Impact of genetic polymorphisms of the beta2-adrenergic receptor on albuterol bronchodilator pharmacodynamics. ( Eberle, LV; Johnson, JA; Lima, JJ; Mohamed, MH; Self, TH; Thomason, DB, 1999) |
| " Lymphocyte beta2-adrenoceptor parameters and a dose-response curve to inhaled albuterol (200 to 1600 microg) were evaluated at 36 hours after the last dose of each treatment period." | 2.69 | Beta2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma. ( Aziz, I; Hall, IP; Lipworth, BJ; McFarlane, LC, 1998) |
| "In subjects with persistent asthma, the ADRB2 Arg16Gly polymorphism does not alter lung function responses to SAL or FSC over the 12 hour dosing interval following acute and chronic dosing." | 1.35 | Acute and chronic lung function responses to salmeterol and salmeterol plus fluticasone propionate in relation to Arg16Gly beta(2)-adrenergic polymorphisms. ( Anderson, WH; Edwards, LD; Klotsman, M; Ortega, HG; Yancey, SW, 2009) |
| "The patient's bronchial asthma attack was ascribed to SNMC." | 1.30 | [Bronchial asthma due to Stronger Neo-Minophagen C]. ( Abe, T; Fujimura, M; Matsuda, T; Nakatsumi, Y; Nomura, G, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.89) | 18.7374 |
| 1990's | 13 (36.11) | 18.2507 |
| 2000's | 10 (27.78) | 29.6817 |
| 2010's | 8 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niu, C | 1 |
| Wang, T | 1 |
| Zou, W | 1 |
| Hu, J | 1 |
| Ying, L | 1 |
| Zhang, M | 1 |
| Liu, J | 1 |
| Tian, D | 1 |
| Dai, J | 1 |
| Luo, Z | 1 |
| Liu, E | 1 |
| Zou, L | 1 |
| Xiong, Y | 1 |
| Fu, Z | 1 |
| Zheng, JQ | 1 |
| Zhang, GR | 1 |
| Li, J | 1 |
| Bi, HW | 1 |
| Fitzpatrick, AM | 2 |
| Park, Y | 2 |
| Brown, LA | 2 |
| Jones, DP | 2 |
| Amaral, AF | 1 |
| Loureiro, CC | 1 |
| Bousquet, J | 1 |
| Todo Bom, A | 1 |
| Rocha, SM | 1 |
| Slankard, M | 1 |
| Michelis, MA | 1 |
| Mansukhani, M | 1 |
| McGoey, B | 1 |
| Paige, A | 1 |
| Andrews, H | 1 |
| Lederer, D | 1 |
| Canfield, S | 1 |
| DiMango, E | 1 |
| BUBERT, HM | 1 |
| COOK, S | 1 |
| Carroll, CL | 1 |
| Stoltz, P | 1 |
| Schramm, CM | 1 |
| Zucker, AR | 1 |
| Yancey, SW | 2 |
| Klotsman, M | 1 |
| Ortega, HG | 2 |
| Edwards, LD | 1 |
| Anderson, WH | 2 |
| Finkelstein, Y | 1 |
| Bournissen, FG | 1 |
| Hutson, JR | 1 |
| Shannon, M | 1 |
| Bleecker, ER | 1 |
| Nelson, HS | 1 |
| Kraft, M | 1 |
| Corren, J | 1 |
| Meyers, DA | 1 |
| Emmett, AH | 1 |
| Sims, EJ | 1 |
| Lipworth, BJ | 4 |
| Fogarty, A | 1 |
| Broadfield, E | 1 |
| Lewis, S | 1 |
| Lawson, N | 1 |
| Britton, J | 1 |
| Yin, K | 1 |
| Zhang, X | 1 |
| Qiu, Y | 1 |
| Cichy, M | 1 |
| Adamek-Guzik, T | 1 |
| Uracz, D | 1 |
| Uracz, W | 1 |
| Czerniawska-Mysik, G | 1 |
| Korbut, R | 1 |
| Guzik, TJ | 1 |
| Dotta, F | 1 |
| Ciani, A | 1 |
| Acone, A | 1 |
| Nava, D | 1 |
| Fujimoto, K | 1 |
| Kubo, K | 1 |
| Shinozaki, S | 1 |
| Okada, K | 1 |
| Matsuzawa, Y | 1 |
| Kobayashi, T | 1 |
| Sugane, K | 1 |
| Turki, J | 1 |
| Pak, J | 1 |
| Green, SA | 1 |
| Martin, RJ | 2 |
| Liggett, SB | 2 |
| Ismaïl, A | 1 |
| Bousaffara, R | 1 |
| Kaziz, J | 1 |
| Zili, J | 1 |
| el Kamel, A | 1 |
| Tahar Sfar, M | 1 |
| Remadi, S | 1 |
| Chouchane, L | 1 |
| Martinez, FD | 1 |
| Graves, PE | 1 |
| Baldini, M | 1 |
| Solomon, S | 1 |
| Erickson, R | 1 |
| Aziz, I | 3 |
| Hall, IP | 1 |
| McFarlane, LC | 1 |
| Hancox, RJ | 1 |
| Sears, MR | 1 |
| Taylor, DR | 1 |
| Weir, TD | 1 |
| Mallek, N | 1 |
| Sandford, AJ | 1 |
| Bai, TR | 1 |
| Awadh, N | 1 |
| Fitzgerald, JM | 1 |
| Cockcroft, D | 1 |
| James, A | 1 |
| Paré, PD | 1 |
| Nakatsumi, Y | 1 |
| Abe, T | 1 |
| Nomura, G | 1 |
| Fujimura, M | 1 |
| Matsuda, T | 1 |
| Green, SL | 1 |
| Gaillard, MC | 1 |
| Song, E | 1 |
| Dewar, JB | 1 |
| Halkas, A | 1 |
| D'amato, M | 1 |
| Vitiani, LR | 1 |
| Petrelli, G | 1 |
| Ferrigno, L | 1 |
| di Pietro, A | 1 |
| Trezza, R | 1 |
| Matricardi, PM | 1 |
| Lima, JJ | 1 |
| Thomason, DB | 1 |
| Mohamed, MH | 1 |
| Eberle, LV | 1 |
| Self, TH | 1 |
| Johnson, JA | 1 |
| Ishizawa, M | 1 |
| Shibasaki, M | 1 |
| Yokouchi, Y | 1 |
| Noguchi, E | 1 |
| Arinami, T | 1 |
| Yamakawa-Kobayashi, K | 1 |
| Matsui, A | 1 |
| Hamaguchi, H | 1 |
| Dempsey, OJ | 2 |
| Laprise, C | 1 |
| Boulet, LP | 1 |
| Morissette, J | 1 |
| Winstall, E | 1 |
| Raymond, V | 1 |
| Wilson, AM | 1 |
| Goldin, J | 1 |
| Hayhurst, M | 1 |
| Potgieter, PD | 1 |
| Kammermeyer, JK | 1 |
| Mathews, KP | 1 |
| Glass, RD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-Blind Comparison of Advair 100/50 BID vs Salmeterol BID vs Albuterol QID in Subjects With ARG/ARG Genotype 12 Years of Age and Older With Presistent Asthma on Short-Acting Beta2-Agonists Alone[NCT00102882] | Phase 4 | 547 participants (Actual) | Interventional | 2004-10-31 | Completed | ||
| [NCT00005475] | 0 participants | Observational | 1996-08-31 | Completed | |||
| Methods to Identify and Treat Severe Asthma Patients Project 1: GSNOR Phenotyping and GSNO Challenge[NCT03926741] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2019-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for glycine and Asthma, Bronchial
| Article | Year |
|---|---|
Polymorphism of the ADRB2 gene and response to inhaled beta- agonists in children with asthma: a meta-analysis.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Arginine; Asthma; Black or African Am | 2009 |
Nocturnal asthma and the use of theophylline.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Anti-Inflammatory Agents; Asthma; Bronchial Provocation Tests; | 1998 |
6 trials available for glycine and Asthma, Bronchial
| Article | Year |
|---|---|
Impact of the Arg 16 allele of the B2AR gene on the effect of withdrawal of LABA in patients with moderate to severe asthma.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Alleles; Anti-Asthmatic Agents; Arginine; | 2016 |
Beta2-receptor polymorphisms in patients receiving salmeterol with or without fluticasone propionate.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Androstadiene | 2010 |
Beta2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Al | 1998 |
Polymorphism of the beta2-adrenoceptor and the response to long-term beta2-agonist therapy in asthma.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Asthma; Double-Blind Method; Down-Regulation; | 1998 |
Functional antagonism with formoterol and salmeterol in asthmatic patients expressing the homozygous glycine-16 beta(2)-adrenoceptor polymorphism.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonist | 2000 |
Effects of adding a leukotriene antagonist or a long-acting beta(2)-agonist in asthmatic patients with the glycine-16 beta(2)-adrenoceptor genotype.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aged; Anti-Asthmatic Agents; Asthma; Be | 2000 |
28 other studies available for glycine and Asthma, Bronchial
| Article | Year |
|---|---|
Enhanced pause correlates with airway neutrophils and airway-epithelial injury in asthmatic mice treated with dexamethasone.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Mode | 2019 |
Neutrophil elastase inhibitor suppresses oxidative stress in obese asthmatic rats by activating Keap1/Nrf2 signaling pathway.
Topics: Animals; Antioxidants; Asthma; Disease Models, Animal; Glycine; Humans; Kelch-Like ECH-Associated Pr | 2019 |
Children with severe asthma have unique oxidative stress-associated metabolomic profiles.
Topics: Adolescent; Adrenal Cortex Hormones; Asthma; Child; Chromatography, High Pressure Liquid; Computatio | 2014 |
Metabolomics of asthma.
Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Ser | 2014 |
Reply: To PMID 24369803.
Topics: Asthma; Carnitine; Ethanolamines; Female; Glycine; Humans; Male; Methylamines; Oxidative Stress; Ser | 2014 |
Reply: To PMID 24369802.
Topics: Asthma; Ethanolamines; Female; Glycine; Humans; Male; Oxidative Stress; Serine; Sphingosine N-Acyltr | 2014 |
Combined thioglycolate and penicillin aerosol in the treatment of severe asthma; preliminary report.
Topics: Aerosols; Asthma; Glycine; Penicillins; Thioglycolates | 1948 |
Beta2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations.
Topics: Adolescent; Adrenergic beta-Agonists; Albuterol; Asthma; Child; Child, Preschool; Disease Progressio | 2009 |
Acute and chronic lung function responses to salmeterol and salmeterol plus fluticasone propionate in relation to Arg16Gly beta(2)-adrenergic polymorphisms.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Amino Acid Substitution; Androstadienes; Arginine; Asthm | 2009 |
Concomitant occasional use of salbutamol influences bronchoprotective responsiveness afforded by formoterol in patients with the glycine-16 genotype.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchoconstriction; Cholinergic Antagonists; Et | 2004 |
Amino acids and asthma: a case-control study.
Topics: Adolescent; Adult; Aged; Amino Acids; Arginine; Asthma; Case-Control Studies; Cystine; Fasting; Fema | 2004 |
Association between beta2-adrenergic receptor genetic polymorphisms and nocturnal asthmatic patients of Chinese Han nationality.
Topics: Adult; Amino Acid Substitution; Asian People; Asthma; China; DNA; DNA Probes; Forced Expiratory Flow | 2006 |
[The functional relevance of Arg16Gly and Gln27Glu-beta2-adrenoreceptor polymorphism in patients with asthma and allergic rhinitis].
Topics: Adolescent; Adult; Aged; Arginine; Asthma; Female; Gene Frequency; Glutamic Acid; Glutamine; Glycine | 2005 |
[Efficacy of mucotropic agents in the treatment of bronchial asthma. Preliminary study of 2-(alpha-thenoylthio)-propionylglycine].
Topics: Adult; Asthma; Drug Evaluation; Expectorants; Female; Glycine; Humans; Male; Middle Aged; Sulfides; | 1983 |
Neutrophil elastase inhibitor reduces asthmatic responses in allergic sheep.
Topics: Airway Resistance; Animals; Antigens; Asthma; Benzoquinones; Bronchial Hyperreactivity; Bronchoalveo | 1995 |
Genetic polymorphisms of the beta 2-adrenergic receptor in nocturnal and nonnocturnal asthma. Evidence that Gly16 correlates with the nocturnal phenotype.
Topics: Alleles; Asthma; Base Sequence; Cohort Studies; Female; Forced Expiratory Volume; Genotype; Glycine; | 1995 |
Polymorphism in transporter antigen peptides gene (TAP1) associated with atopy in Tunisians.
Topics: Adolescent; Alleles; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Ca | 1997 |
Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing.
Topics: Adrenergic beta-Agonists; Albuterol; Alleles; Arginine; Asthma; Bronchodilator Agents; Child; Glutam | 1997 |
Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing.
Topics: Adrenergic beta-Agonists; Albuterol; Alleles; Arginine; Asthma; Bronchodilator Agents; Child; Glutam | 1997 |
Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing.
Topics: Adrenergic beta-Agonists; Albuterol; Alleles; Arginine; Asthma; Bronchodilator Agents; Child; Glutam | 1997 |
Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing.
Topics: Adrenergic beta-Agonists; Albuterol; Alleles; Arginine; Asthma; Bronchodilator Agents; Child; Glutam | 1997 |
beta2-Adrenergic receptor haplotypes in mild, moderate and fatal/near fatal asthma.
Topics: Adrenergic beta-Agonists; Adult; Alleles; Amino Acids; Anti-Asthmatic Agents; Asian People; Asthma; | 1998 |
[Bronchial asthma due to Stronger Neo-Minophagen C].
Topics: Adult; Anti-Inflammatory Agents; Asthma; Cysteine; Drug Combinations; Female; Glycine; Glycyrrhetini | 1998 |
Polymorphisms of the beta chain of the high-affinity immunoglobulin E receptor (Fcepsilon RI-beta) in South African black and white asthmatic and nonasthmatic individuals.
Topics: Adolescent; Adult; Asthma; Black People; Chi-Square Distribution; Child; Exons; Female; Gene Frequen | 1998 |
Association of persistent bronchial hyperresponsiveness with beta2-adrenoceptor (ADRB2) haplotypes. A population study.
Topics: Adolescent; Adult; Allergens; Amino Acid Sequence; Asthma; Bronchial Hyperreactivity; Bronchial Prov | 1998 |
Impact of genetic polymorphisms of the beta2-adrenergic receptor on albuterol bronchodilator pharmacodynamics.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Arginine; Asthma; Bronchodilator Agents; Female; Forced | 1999 |
No association between atopic asthma and a coding variant of Fc epsilon R1 beta in a Japanese population.
Topics: Amino Acid Substitution; Asian People; Asthma; Genetic Variation; Glutamic Acid; Glycine; Humans; Ja | 1999 |
Evidence for association and linkage between atopy, airway hyper-responsiveness, and the beta subunit Glu237Gly variant of the high-affinity receptor for immunoglobulin E in the French-Canadian population.
Topics: Adult; Asthma; Canada; Case-Control Studies; Female; France; Genetic Linkage; Genetic Variation; Glu | 2000 |
Severe asthma due to intravenous avapyrazone and dipyrone.
Topics: Adult; Aminopyrine; Analgesics; Asthma; Dipyrone; Drug Combinations; Female; Glycine; Humans; Phenyl | 1986 |
Hypersensitivity to phenylglycine acid chloride.
Topics: Acids; Allergens; Aminocaproates; Asthma; Chemical Industry; Chlorides; Dust; Environmental Exposure | 1973 |
Experience with disodium cromoglycate in the treatment of asthmatic children.
Topics: Adolescent; Asthma; Body Height; Body Weight; Child; Chromones; Cromolyn Sodium; Glycine; Growth; Hu | 1971 |