Page last updated: 2024-10-18

glycine and Adenocarcinoma

glycine has been researched along with Adenocarcinoma in 33 studies

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" Immunodeficient mice were inoculated intrafemorally with the human breast adenocarcinoma cell line MDA-MB-231, then treated 14days later via mini-osmotic pumps inserted intraperitoneally with sulfasalazine, (S)-4-carboxyphenylglycine, or vehicle."7.80Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. ( Seidlitz, EP; Singh, G; Ungard, RG, 2014)
"Using PCR based restriction fragment length polymorphism and single strand conformational polymorphism, we determined single nucleotide exchanges in the p16 and cyclin D1 genes among 56 esophageal adenocarcinomas (ADC) arising in Barrett's esophagus, 95 cardiac gastric ADC, and in 191 distal gastric ADC."7.73Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract. ( Gabbert, HE; Geddert, H; Kiel, S; Sarbia, M; Willers, R; Zhang, J; Zotz, RB, 2005)
"Forphenicinol, S-2-(3-hydroxy-4-hydroxymethylphenyl)glycine, prolonged the survival period of mice implanted with Meth A fibrosarcoma or Lewis lung carcinoma."7.67Antitumor effect of forphenicinol, a low molecular weight immunomodifier, in combination with surgery on Meth A fibrosarcoma, Lewis lung carcinoma, and adenocarcinoma 755. ( Ishizuka, M; Naito, K; Okura, A; Sawazaki, Y; Takeuchi, T; Umezawa, H, 1986)
" In this study, rigosertib was assessed in combination with gemcitabine in patients with treatment-naïve metastatic pancreatic adenocarcinoma."5.20A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer. ( Aisner, DL; Bajaj, R; Baranda, JC; Bathini, V; Berlin, J; Boles, J; Cho, JK; Cohen, DJ; Cohen, SJ; Coveler, L; Cusnir, M; Fanta, P; Fehrenbacher, L; Gomes, CL; Granfortuna, J; Jimeno, A; Ma, WW; Maguire, R; Maniar, M; McRee, AJ; Menter, AR; Messersmith, WA; Nazemzadeh, R; O'Neil, BH; Olowokure, OO; Phillip, P; Radford, J; Rarick, M; Scott, AJ; Tejani, MA; Wilhelm, F, 2015)
" Immunodeficient mice were inoculated intrafemorally with the human breast adenocarcinoma cell line MDA-MB-231, then treated 14days later via mini-osmotic pumps inserted intraperitoneally with sulfasalazine, (S)-4-carboxyphenylglycine, or vehicle."3.80Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain. ( Seidlitz, EP; Singh, G; Ungard, RG, 2014)
"Using PCR based restriction fragment length polymorphism and single strand conformational polymorphism, we determined single nucleotide exchanges in the p16 and cyclin D1 genes among 56 esophageal adenocarcinomas (ADC) arising in Barrett's esophagus, 95 cardiac gastric ADC, and in 191 distal gastric ADC."3.73Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract. ( Gabbert, HE; Geddert, H; Kiel, S; Sarbia, M; Willers, R; Zhang, J; Zotz, RB, 2005)
" To address this problem, we have measured the synthetic rate of fibrinogen (perhaps the major acute phase protein) and plasma amino acid profiles in a group of patients with adenocarcinoma of the pancreas and an ongoing inflammatory response (serum C-reactive protein >10 mg/L in the absence of any other obvious infective or inflammatory cause)."3.70Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response. ( Falconer, JS; Fearon, KC; McMillan, DC; Preston, T; Shenkin, A; Slater, C, 1998)
"Forphenicinol, S-2-(3-hydroxy-4-hydroxymethylphenyl)glycine, prolonged the survival period of mice implanted with Meth A fibrosarcoma or Lewis lung carcinoma."3.67Antitumor effect of forphenicinol, a low molecular weight immunomodifier, in combination with surgery on Meth A fibrosarcoma, Lewis lung carcinoma, and adenocarcinoma 755. ( Ishizuka, M; Naito, K; Okura, A; Sawazaki, Y; Takeuchi, T; Umezawa, H, 1986)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19906 (18.18)18.7374
1990's11 (33.33)18.2507
2000's7 (21.21)29.6817
2010's8 (24.24)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Banh, RS1
Biancur, DE1
Yamamoto, K1
Sohn, ASW1
Walters, B1
Kuljanin, M1
Gikandi, A1
Wang, H1
Mancias, JD1
Schneider, RJ1
Pacold, ME1
Kimmelman, AC1
Engür, S1
Dikmen, M1
Straub, D1
Oude Elferink, RPJ1
Jansen, PLM1
Bergman, JJGHM1
Parikh, K1
Krishnadath, KK1
Ungard, RG1
Seidlitz, EP1
Singh, G1
Yamamoto, H1
Higasa, K1
Sakaguchi, M1
Shien, K1
Soh, J1
Ichimura, K1
Furukawa, M1
Hashida, S1
Tsukuda, K1
Takigawa, N1
Matsuo, K1
Kiura, K1
Miyoshi, S1
Matsuda, F1
Toyooka, S1
O'Neil, BH1
Scott, AJ1
Ma, WW1
Cohen, SJ1
Aisner, DL1
Menter, AR1
Tejani, MA1
Cho, JK1
Granfortuna, J1
Coveler, L1
Olowokure, OO1
Baranda, JC1
Cusnir, M1
Phillip, P1
Boles, J1
Nazemzadeh, R1
Rarick, M1
Cohen, DJ1
Radford, J1
Fehrenbacher, L1
Bajaj, R1
Bathini, V1
Fanta, P1
Berlin, J1
McRee, AJ1
Maguire, R1
Wilhelm, F1
Maniar, M1
Jimeno, A1
Gomes, CL1
Messersmith, WA1
Lito, P1
Solomon, M1
Li, LS1
Hansen, R1
Rosen, N1
Calabrese, C1
Pisi, A1
Di Febo, G1
Liguori, G1
Filippini, G1
Cervellera, M1
Righi, V1
Lucchi, P1
Mucci, A1
Schenetti, L1
Tonini, V1
Tosi, MR1
Tugnoli, V1
Degrassi, A1
Russo, M1
Nanni, C1
Patton, V1
Alzani, R1
Giusti, AM1
Fanti, S1
Ciomei, M1
Pesenti, E1
Texido, G1
Rachagani, S1
Senapati, S1
Chakraborty, S1
Ponnusamy, MP1
Kumar, S1
Smith, LM1
Jain, M1
Batra, SK1
GITTERMAN, CO1
DULANEY, EL1
KACZKA, EA1
CAMPBELL, GW1
HENDLIN, D1
WOODRUFF, HB1
Koh, TJ1
Field, JK1
Varro, A1
Liloglou, T1
Fielding, P1
Cui, G1
Houghton, J1
Dockray, GJ1
Wang, TC1
Gross, I1
Lhermitte, B1
Domon-Dell, C1
Duluc, I1
Martin, E1
Gaiddon, C1
Kedinger, M1
Freund, JN1
Geddert, H1
Kiel, S1
Zotz, RB1
Zhang, J1
Willers, R1
Gabbert, HE1
Sarbia, M1
Giger, U1
Büchler, M1
Farhadi, J1
Berger, D1
Hüsler, J1
Schneider, H1
Krähenbühl, S1
Krähenbühl, L1
Wiesen, KM1
Xia, S1
Yang, CP1
Horwitz, SB1
Mori, M1
Iwasaki, T1
Nakazawa, Y1
Namba, Y1
Niinaka, M1
Yano, Y1
Kitada, S1
Kimura, H1
Naka, N1
Okada, T1
Nakagawa, M1
Maekura, R1
Yokota, S1
Fossum, B1
Gedde-Dahl, T1
Breivik, J1
Eriksen, JA1
Spurkland, A1
Thorsby, E1
Gaudernack, G1
Finkelstein, SD1
Przygodzki, R1
Pricolo, VE1
Sayegh, R1
Bakker, A1
Swalsky, PA1
Keller, G1
Gan, LS1
Niederer, T1
Eads, C1
Thakker, D1
Capaccioli, S1
Di Pasquale, G1
Mini, E1
Mazzei, T1
Quattrone, A1
Richards, EW1
Long, CL1
Nelson, KM1
Tohver, OK1
Pinkston, JA1
Navari, RM1
Blakemore, WS1
Furuishi, K1
Misumi, S1
Shoji, S1
Inada, M1
Yamashita, J1
Ogawa, M2
Kamohara, H1
Sakamoto, K1
Mita, S1
An, XY1
Preston, T1
Slater, C1
McMillan, DC1
Falconer, JS1
Shenkin, A1
Fearon, KC1
Al-Mulla, F1
Going, JJ1
Sowden, ET1
Winter, A1
Pickford, IR1
Birnie, GD1
Lozonschi, L1
Sunamura, M1
Kobari, M1
Egawa, S1
Ding, L1
Matsuno, S1
Watanabe, J1
Holinka, CF1
Anzai, Y1
Kuramoto, H1
Gurpide, E1
Okura, A1
Sawazaki, Y1
Naito, K1
Ishizuka, M1
Takeuchi, T1
Umezawa, H1
Bibby, MC1
Double, JA1
Hill, DL1
Straight, S1
Kasten, FH1
Strasser, FF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III, Multi-center, Randomized, Controlled Study to Compare the Efficacy and Safety of Gemcitabine Alone vs. ON 01910.Na Combined With Gemcitabine in Patients With Previously Untreated Metastatic Pancreatic Cancer[NCT01360853]Phase 3160 participants (Actual)Interventional2011-05-31Completed
Investigating the Use of a Preoperative High-Arginine Nutritional Supplement Prior to Radical Cystectomy[NCT02655081]Phase 248 participants (Actual)Interventional2015-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for glycine and Adenocarcinoma

ArticleYear
A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Comb

2015
Preoperative immunonutrition suppresses perioperative inflammatory response in patients with major abdominal surgery-a randomized controlled pilot study.
    Annals of surgical oncology, 2007, Volume: 14, Issue:10

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; C-Reactive Protein; Enteral

2007

Other Studies

31 other studies available for glycine and Adenocarcinoma

ArticleYear
Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer.
    Cell, 2020, 11-25, Volume: 183, Issue:5

    Topics: Adenocarcinoma; Aged; Animals; Axons; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Prolifera

2020
The evaluation of the anti-cancer activity of ixazomib on Caco2 colon solid tumor cells, comparison with bortezomib.
    Acta clinica Belgica, 2017, Volume: 72, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents; Boron Compounds; Bortezomib; Caco-2 Cells; Caspase 3; Colonic

2017
Glyco-conjugated bile acids drive the initial metaplastic gland formation from multi-layered glands through crypt-fission in a murine model.
    PloS one, 2019, Volume: 14, Issue:7

    Topics: Adenocarcinoma; Animals; Barrett Esophagus; Bile Acids and Salts; Chromatography, High Pressure Liqu

2019
Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain.
    Pain, 2014, Volume: 155, Issue:1

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bone and Bones; Breast

2014
Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Asian People; Aspartic Acid; Female; Genetic Predispo

2014
Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism.
    Science (New York, N.Y.), 2016, Feb-05, Volume: 351, Issue:6273

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Alleles; Antineoplastic Agents; Azetidines; Cell Line, Tumor

2016
Biochemical alterations from normal mucosa to gastric cancer by ex vivo magnetic resonance spectroscopy.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:6

    Topics: Adenocarcinoma; Aged; Alanine; Biomarkers, Tumor; Choline; Endoscopy, Gastrointestinal; Female; Gast

2008
Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-Ras(G12D)LA2 lung adenocarcinoma transgenic mouse model: evaluation by multimodality imaging.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Antineoplastic Agents; Aspartic Acid; Cyclin-Depen

2010
Activated KrasG¹²D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin.
    British journal of cancer, 2011, Mar-15, Volume: 104, Issue:6

    Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Aspartic Acid; Cadherins; Down-Regulation; Gene Ex

2011
THE HUMAN TUMOR-EGG HOST SYSTEM. III. TUMOR-INHIBITORY PROPERTIES OF TENUAZONIE ACID.
    Cancer research, 1964, Volume: 24

    Topics: Adenocarcinoma; Antineoplastic Agents; Aspergillus; Azaserine; Carcinoma, Bronchogenic; Chick Embryo

1964
Glycine-extended gastrin promotes the growth of lung cancer.
    Cancer research, 2004, Jan-01, Volume: 64, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma,

2004
Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.
    Oncogene, 2005, Dec-01, Volume: 24, Issue:54

    Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Substitution; Animals

2005
Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alanine; Barrett Esophagus; Cardia; Case-Control Stu

2005
Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation.
    Cancer letters, 2007, Nov-18, Volume: 257, Issue:2

    Topics: Adenocarcinoma; Alkanes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carbamates; Cell Line,

2007
[A case of lung adenocarcinoma effectively treated with sivelestat and corcicosteroid for drug-induced lung disease due to gefitinib].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2008, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Gefitinib; Glycine; Humans; Lung Diseases; Lung Neoplas

2008
p21-ras-peptide-specific T-cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly-->Asp).
    International journal of cancer, 1994, Jan-02, Volume: 56, Issue:1

    Topics: Adenocarcinoma; Amino Acid Sequence; Aspartic Acid; CD4-Positive T-Lymphocytes; CD8 Antigens; Cells,

1994
K-ras-2 topographic genotyping of pancreatic adenocarcinoma.
    Archives of surgery (Chicago, Ill. : 1960), 1994, Volume: 129, Issue:4

    Topics: Adenocarcinoma; Alanine; Arginine; Aspartic Acid; Codon; Cysteine; DNA, Neoplasm; Exons; Forecasting

1994
Evidence for predominantly paracellular transport of thyrotropin-releasing hormone across CACO-2 cell monolayers.
    Biochemical and biophysical research communications, 1993, Dec-15, Volume: 197, Issue:2

    Topics: 2,4-Dinitrophenol; Adenocarcinoma; Amiloride; Azides; Biological Transport; Cell Line; Cell Membrane

1993
Cationic lipids improve antisense oligonucleotide uptake and prevent degradation in cultured cells and in human serum.
    Biochemical and biophysical research communications, 1993, Dec-15, Volume: 197, Issue:2

    Topics: 3T3 Cells; Adenocarcinoma; Animals; Base Sequence; Biological Transport; Cell Line; Colonic Neoplasm

1993
Protein turnover in advanced lung cancer patients.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:3

    Topics: Adenocarcinoma; Aged; Blood Urea Nitrogen; Body Mass Index; Body Weight; Calorimetry; Carcinoma, Squ

1993
A novel monoclonal antibody to N-myristoyl glycine moiety found a new N-myristoylated HIV-1 p28gag protein in HIV-1-infected cells.
    Biochemical and biophysical research communications, 1996, May-15, Volume: 222, Issue:2

    Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibody Specificity; Avian Sarcoma Viruses; Cells,

1996
Neutrophil elastase inhibitor (ONO-5046-Na) inhibits the growth of human lung cancer cell lines transplanted into severe combined immunodeficiency (scid) mice.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 97, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous

1997
Neutrophil elastase inhibitor (ONO-5046.Na) suppresses the proliferation, motility and chemotaxis of a pancreatic carcinoma cell line, Capan-1.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 98, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Movement; Chemotaxi

1997
Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response.
    The Journal of nutrition, 1998, Volume: 128, Issue:8

    Topics: Acute-Phase Reaction; Adenocarcinoma; Adult; Aged; Amino Acids; C-Reactive Protein; Cachexia; Fastin

1998
Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortality.
    The Journal of pathology, 1998, Volume: 185, Issue:2

    Topics: Adenocarcinoma; Adenoma; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Genes, ras; Genetic H

1998
Controlling tumor angiogenesis and metastasis of C26 murine colon adenocarcinoma by a new matrix metalloproteinase inhibitor, KB-R7785, in two tumor models.
    Cancer research, 1999, Mar-15, Volume: 59, Issue:6

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Glycine; Hydroxamic Acids; Lung Neoplasms; Male; Metallo

1999
Effects of serine and glycine on proliferation of an Ishikawa cell variant.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: Adenocarcinoma; Adult; Breast Neoplasms; Cell Division; Cell Line; DNA Replication; DNA, Neoplasm; F

1989
Antitumor effect of forphenicinol, a low molecular weight immunomodifier, in combination with surgery on Meth A fibrosarcoma, Lewis lung carcinoma, and adenocarcinoma 755.
    The Journal of antibiotics, 1986, Volume: 39, Issue:4

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Combined Modality Ther

1986
Activity of N-[N'-(2-chloroethyl)-N'-nitrosocarbamoyl]-alanine and derivatives against transplantable adenocarcinomata of the mouse colon (MAC).
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:1

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alanine; Animals; Antineoplastic Agents; Colonic Neoplasms; D

1986
Effects of 6-N-allyladenosine on bacterial and mammalian cells.
    Molecular pharmacology, 1970, Volume: 6, Issue:5

    Topics: Adenocarcinoma; Amides; Azaserine; Carcinoma; Cell Line; Culture Techniques; Escherichia coli; Glyci

1970
Amino acid incorporation patterns during the cell cycle of synchronized human tumor cells.
    National Cancer Institute monograph, 1966, Volume: 23

    Topics: Adenocarcinoma; Amino Acids; Arginine; Autoradiography; Cell Division; Cell Nucleus; Culture Techniq

1966