Page last updated: 2024-10-18

glycine and Acute Disease

glycine has been researched along with Acute Disease in 109 studies

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"To compare 3-month stroke outcomes and stroke-related health care resource use between the US and Canada in the Glycine Antagonist in Neuroprotection (GAIN) Americas study."9.11Health care resource use after acute stroke in the Glycine Antagonist in Neuroprotection (GAIN) Americas trial. ( Hux, M; Johnston, KC; Nielsen, K; Phillips, S; Rundek, T; Watson, D, 2004)
"Oral administration of ESL (100 mg/kg), previous to latrunculin A microperfusion, completely prevented acute latrunculin A-induced seizures as well as chronic seizures and all EEG chronic signs of paroxysmal activity."7.80Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus. ( Loureiro, AI; Sierra-Marcuño, G; Sierra-Paredes, G; Soares-da-Silva, P; Wright, LC, 2014)
"The authors evaluated the protective effect of sivelestat sodium on postoperative lung dysfunction in patients with type A acute aortic dissection who underwent aortic arch surgery with cardiopulmonary bypass (CPB) under deep hypothermia with circulatory arrest (DHCA)."7.74Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study. ( Dardik, A; Kainuma, M; Kondo, Y; Muto, A; Nishibe, T; Ohara, Y; Takeda, K, 2008)
"The present study investigated whether chemokines are involved in hydrogen sulfide (H2S)-associated pathogenesis of acute pancreatitis and associated lung injury."7.74Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury. ( Bhatia, M; Moore, PK; Tamizhselvi, R, 2008)
"Mice with thermal and mechanical hypersensitivity after partial ligation of the sciatic nerve (Seltzer model) or mice with mechanical hypersensitivity after streptozotocin injection received intrathecal injection of glycine, sarcosine, and N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine."7.74Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment. ( Kodama, D; Ono, H; Takasu, K; Tanabe, M; Yamaguchi, S, 2008)
"Morphine-augmented cholescintigraphy optimizes the diagnosis of acute cholecystitis in patients with the suggestive, but not pathognomonic, cholescintigraphic pattern at 1 hr of gallbladder nonvisualization with a pericholecystic rim sign, regardless of its intensity."7.69Gallbladder nonvisualization with pericholecystic rim sign: morphine-augmentation optimizes diagnosis of acute cholecystitis. ( Achong, DM; Chin, CT; Oates, E; Selland, DL, 1996)
"The utility of morphine-augmented cholescintigraphy was reviewed in 32 patients with suspected acute cholecystitis."7.68Morphine-augmented cholescintigraphy in acute cholecystitis. A satisfactory alternative to delayed imaging. ( Bitterman, P; Gooch, D; Kistler, AM; Ziessman, HA, 1991)
"Acute hypotension was induced by intravenous infusion of sodium nitroprusside (SNP)."5.36[Changes of gamma-aminobutyric acid and glycine released in the medial vestibular nucleus following acute hypotension in conscious rats]. ( An, Y; Jin, QH; Jin, YZ; Li, XL, 2010)
"Acute pancreatitis was induced in mice by 10 hourly intraperitoneal injections of caerulein (50 (g/kg)."5.35Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis. ( Bhatia, M; Moochhala, SM; Ng, SW; Sidhapuriwala, JN; Tamizhselvi, R, 2008)
"Hydrogen sulfide (H2S) is a naturally occurring gas with potent vasodilator activity."5.33Role of hydrogen sulfide in acute pancreatitis and associated lung injury. ( Bhatia, M; Fu, D; Lau, HY; Moochhala, SM; Moore, PK; Wong, FL, 2005)
"Acute cholecystitis was deemed present if there was nonvisualization of the gallbladder 30 min post-morphine administration; no cystic duct obstruction was present if the gallbladder was demonstrated pre- or post-morphine administration."5.28Morphine-augmented cholescintigraphy: its efficacy in detecting acute cholecystitis. ( Balon, H; Fink-Bennett, D; Robbins, T; Tsai, D, 1991)
"We analyzed data from the Glycine Antagonist in Neuroprotection (GAIN) Americas trial, in which 1604 non-obtunded patients with acute stroke were treated within 6 hours of symptom onset irrespective of hemorrhagic (N = 237) versus ischemic (N = 1367) subtype."5.14Comparison of outcomes after intracerebral hemorrhage and ischemic stroke. ( Chiu, D; Elkind, MSV; Gerber, LM; Peterson, L; Rosand, J; Silverstein, MD, 2010)
"To compare 3-month stroke outcomes and stroke-related health care resource use between the US and Canada in the Glycine Antagonist in Neuroprotection (GAIN) Americas study."5.11Health care resource use after acute stroke in the Glycine Antagonist in Neuroprotection (GAIN) Americas trial. ( Hux, M; Johnston, KC; Nielsen, K; Phillips, S; Rundek, T; Watson, D, 2004)
"Oral administration of ESL (100 mg/kg), previous to latrunculin A microperfusion, completely prevented acute latrunculin A-induced seizures as well as chronic seizures and all EEG chronic signs of paroxysmal activity."3.80Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus. ( Loureiro, AI; Sierra-Marcuño, G; Sierra-Paredes, G; Soares-da-Silva, P; Wright, LC, 2014)
"Isovaline reduced responses in mouse pain models without producing acute toxicity, possibly by enhancing receptor modulation of nociceptive information."3.76Analgesic properties of the novel amino acid, isovaline. ( Chung, CC; MacLeod, BA; Puil, E; Ries, CR; Schwarz, SK; Wang, JT, 2010)
"The authors evaluated the protective effect of sivelestat sodium on postoperative lung dysfunction in patients with type A acute aortic dissection who underwent aortic arch surgery with cardiopulmonary bypass (CPB) under deep hypothermia with circulatory arrest (DHCA)."3.74Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study. ( Dardik, A; Kainuma, M; Kondo, Y; Muto, A; Nishibe, T; Ohara, Y; Takeda, K, 2008)
"The present study investigated whether chemokines are involved in hydrogen sulfide (H2S)-associated pathogenesis of acute pancreatitis and associated lung injury."3.74Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury. ( Bhatia, M; Moore, PK; Tamizhselvi, R, 2008)
"Mice with thermal and mechanical hypersensitivity after partial ligation of the sciatic nerve (Seltzer model) or mice with mechanical hypersensitivity after streptozotocin injection received intrathecal injection of glycine, sarcosine, and N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine."3.74Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment. ( Kodama, D; Ono, H; Takasu, K; Tanabe, M; Yamaguchi, S, 2008)
"The aim of the present study was to examine whether neutrophil and its elastase activity played consequential roles in the progression of gut barrier dysfunction during acute alveolar hypoxia by using a specific neutrophil elastase inhibitor, sivelestat."3.74Inhibition of neutrophil elastase attenuates gut mucosal injury evoked by acute alveolar hypoxia in rabbits. ( Funakoshi, Y; Ishizaka, A; Katori, N; Kawabata, K; Kotake, Y; Morisaki, H; Nakamura, N; Suzuki, T; Takeda, J; Yajima, S; Yamada, S, 2007)
"Morphine intervention in cholescintigraphy decreases imaging time to diagnose acute cholecystitis."3.69Morphine-augmented cholescintigraphy enhances duodenogastric reflux. ( Lee, JK; Magoun, S; Ryo, UY; Shih, WJ; Wierzbinski, B, 1995)
"Morphine-augmented cholescintigraphy optimizes the diagnosis of acute cholecystitis in patients with the suggestive, but not pathognomonic, cholescintigraphic pattern at 1 hr of gallbladder nonvisualization with a pericholecystic rim sign, regardless of its intensity."3.69Gallbladder nonvisualization with pericholecystic rim sign: morphine-augmentation optimizes diagnosis of acute cholecystitis. ( Achong, DM; Chin, CT; Oates, E; Selland, DL, 1996)
"The utility of morphine-augmented cholescintigraphy was reviewed in 32 patients with suspected acute cholecystitis."3.68Morphine-augmented cholescintigraphy in acute cholecystitis. A satisfactory alternative to delayed imaging. ( Bitterman, P; Gooch, D; Kistler, AM; Ziessman, HA, 1991)
" In order to elucidate the significance of GAA synthesis in the pancreas, the author measured serum concentration of GAA, creatine, and the renal and pancreatic GAT activity in control, streptozotocin (STZ)-induced diabetic, insulin-treated diabetic, and ethionine-induced acute pancreatitis rats."3.67[Study of impaired metabolism of guanidinoacetic acid in uremia--the compensatory role of the pancreas in guanidinoacetic acid synthesis]. ( Hirata, M, 1989)
"When faced with a patient with possible acute cholecystitis, technetium-99m-HIDA scintigraphy should be the primary diagnostic procedure performed."3.66Diagnostic utility of cholescintigraphy and ultrasonography in acute cholecystitis. ( Burrell, MI; Cahow, CE; Caride, V; Zeman, RK, 1981)
" All patients were asked to keep a daily diary to evaluate gastric tolerability, whereas overall tolerability was evaluated by recording adverse effects and determining the common laboratory parameters."2.70[Efficacy and safety of amtolmetin guacyl in the treatment of acute osteoarthritis]. ( Biasi, G; Marcolongo, R, 2001)
" The dosage used in Group A1 was as efficacious as that used in Group A2."2.68[Clinical trial comparing a new NSAID with 2 different dosages and diclofenac in patients with arthralgia in acute phase]. ( Alicicco, E; Delfino, M; Kleszczynski, D, 1995)
" The highest dosage employed (1800 mg/die) performs an excellent therapeutical activity which is equivalent to that at the 1200 mg in reducing pain symptomatology, but on the average less tolerated."2.67[A clinical study to determine the optimal dosage of ST-679 in the treatment of rheumatic diseases]. ( Donati, G; Spinazzè, R, 1993)
"Treatment with GSK4112 also downregulated the activities of caspase-3 and caspase-8, suppressed hepatocyte apoptosis."1.62REV-ERBα Agonist GSK4112 attenuates Fas-induced Acute Hepatic Damage in Mice. ( Fan, K; Jiang, R; Li, L; Liu, G; Shao, R; Shen, Y; Tang, L; Wu, X; Yang, Y; Zhang, L, 2021)
" Further, when the human condition was simulated in animals, there was deprivation in body weight and glucose levels in starved litchi seed dosed rats, causing hypoglycemia."1.51Methylenecyclopropyl glycine, not pesticide exposure as the primary etiological factor underlying hypoglycemic encephalopathy in Muzaffarpur, India. ( Asthana, S; Das, M; Dixit, S; Kumar, A; Singh, SP; Srivastava, A; Tripathi, A, 2019)
"Sivelestat treatment significantly reduced the protein level, neutrophil count, neutrophil elastase activity in BALF, and severity of histopathologic findings on day 14 for mice administered with 250 mg/kg of gefitinib."1.46Neutrophil elastase inhibitor sivelestat ameliorates gefitinib-naphthalene-induced acute pneumonitis in mice. ( Arimura-Omori, M; Hamada, N; Harada, E; Ikeda-Harada, C; Mikumo, H; Nakanishi, Y; Ogata-Suetsugu, S; Suzuki, K; Yanagihara, T; Yokoyama, T, 2017)
"Surgery for type A acute aortic dissection (AAD) is associated with a high mortality and incidence of postoperative complications, including acute respiratory failure and coagulopathy."1.36Efficacy of neutrophil elastase inhibitor on type A acute aortic dissection. ( Fujita, K; Hata, M; Minami, K; Niino, T; Osaka, S; Sezai, A; Shimura, K; Unosawa, S; Yoshitake, I, 2010)
"Acute hypotension was induced by intravenous infusion of sodium nitroprusside (SNP)."1.36[Changes of gamma-aminobutyric acid and glycine released in the medial vestibular nucleus following acute hypotension in conscious rats]. ( An, Y; Jin, QH; Jin, YZ; Li, XL, 2010)
"Acute pancreatitis was induced in mice by 10 hourly intraperitoneal injections of caerulein (50 (g/kg)."1.35Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis. ( Bhatia, M; Moochhala, SM; Ng, SW; Sidhapuriwala, JN; Tamizhselvi, R, 2008)
"Respiratory failure was relieved within 5 days following treatment."1.35[Acute respiratory failure due to pneumocystis pneumonia successfully treated with combined use of sivelestat sodium hydrate]. ( Chida, K; Fujisawa, T; Harada, M; Imokawa, S; Mori, K; Sagisaka, S; Sano, T; Suda, T; Uchiyama, H; Ukita, T; Yasuda, K, 2008)
"Sivelestat is a specific neutrophil elastase inhibitor, and this study aims to evaluate the effects of sivelestat on postoperative respiratory failure due to AAD."1.33The effects of a neutrophil elastase inhibitor on the postoperative respiratory failure of acute aortic dissection. ( Amano, J; Fukui, D; Furusawa, T; Sakaguchi, M; Seto, T; Terasaki, T; Tsukioka, K; Wada, Y, 2006)
"Pretreatment of sivelestat demonstrated a protective effect on both intravascular and extravascular damage in the lung, whereas posttreatment only suppressed the latter damage."1.33Pretreatment of sivelestat sodium hydrate improves the lung microcirculation and alveolar damage in lipopolysaccharide-induced acute lung inflammation in hamsters. ( Fukunaga, M; Iba, T; Kidokoro, A; Sugimotoa, K; Takuhiro, K; Yoshikawa, S, 2006)
"Respiratory failure was relieved within 2 weeks following treatment There was no four-fold rise in screen viral titers and screening investigations of autoantibodies were negative."1.33[Two cases of acute respiratory failure due to idiopathic interstitial pneumonia successfully treated with sivelestat sodium hydrate and steroid therapy]. ( Chida, K; Enomoto, N; Imokawa, S; Nagayama, M; Sano, T; Suda, T; Todate, A; Uchiyama, H; Yasuda, K, 2006)
"Hydrogen sulfide (H2S) is a naturally occurring gas with potent vasodilator activity."1.33Role of hydrogen sulfide in acute pancreatitis and associated lung injury. ( Bhatia, M; Fu, D; Lau, HY; Moochhala, SM; Moore, PK; Wong, FL, 2005)
"Mortality associated with endotoxin shock is likely mediated by Kupffer cells, alveolar macrophages, and circulating neutrophils."1.31Dietary glycine blunts lung inflammatory cell influx following acute endotoxin. ( Enomoto, N; Madren, J; Rose, ML; Seabra, V; Thurman, RG; Wheeler, MD; Yamashima, S, 2000)
"The authors present a case of type II choledochal cyst shown on a hepatobiliary scan in a patient with possible acute cholecystitis."1.31Hepatobiliary scan showing type II choledochal cyst. ( Falen, S; McCartney, W; Wienke, J, 2001)
"Acute pancreatitis is a dreaded complication of biliary calculus disease, and several radiographic signs have been reported in association with this condition."1.28The scintigraphic "duodenal cut off sign" in acute pancreatitis. ( Alexander, HG; Buckner, AB; Shanley, DJ, 1991)
"Acute cholecystitis was deemed present if there was nonvisualization of the gallbladder 30 min post-morphine administration; no cystic duct obstruction was present if the gallbladder was demonstrated pre- or post-morphine administration."1.28Morphine-augmented cholescintigraphy: its efficacy in detecting acute cholecystitis. ( Balon, H; Fink-Bennett, D; Robbins, T; Tsai, D, 1991)

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199027 (24.77)18.7374
1990's26 (23.85)18.2507
2000's34 (31.19)29.6817
2010's19 (17.43)24.3611
2020's3 (2.75)2.80

Authors

AuthorsStudies
Shao, R1
Yang, Y1
Fan, K1
Wu, X1
Jiang, R1
Tang, L1
Li, L1
Shen, Y1
Liu, G1
Zhang, L1
Cerchione, C1
Martinelli, G1
Stuani, L1
Sabatier, M1
Saland, E1
Cognet, G1
Poupin, N1
Bosc, C1
Castelli, FA1
Gales, L1
Turtoi, E1
Montersino, C1
Farge, T1
Boet, E1
Broin, N1
Larrue, C1
Baran, N1
Cissé, MY1
Conti, M1
Loric, S1
Kaoma, T1
Hucteau, A1
Zavoriti, A1
Sahal, A1
Mouchel, PL1
Gotanègre, M1
Cassan, C1
Fernando, L1
Wang, F1
Hosseini, M1
Chu-Van, E1
Le Cam, L1
Carroll, M1
Selak, MA1
Vey, N1
Castellano, R1
Fenaille, F1
Turtoi, A1
Cazals, G1
Bories, P1
Gibon, Y1
Nicolay, B1
Ronseaux, S1
Marszalek, JR1
Takahashi, K1
DiNardo, CD1
Konopleva, M1
Pancaldi, V1
Collette, Y1
Bellvert, F1
Jourdan, F1
Linares, LK1
Récher, C1
Portais, JC1
Sarry, JE1
Asthana, S1
Dixit, S1
Srivastava, A1
Kumar, A1
Singh, SP1
Tripathi, A1
Das, M1
Santarelli, F1
Cassanello, M1
Enea, A1
Poma, F1
D'Onofrio, V1
Guala, G1
Garrone, G1
Puccinelli, P1
Caruso, U1
Porta, F1
Spada, M1
Wang, H1
Wang, S1
Tang, A1
Gong, H1
Ma, P1
Chen, L1
Guercio, GD1
Bevictori, L1
Vargas-Lopes, C1
Madeira, C1
Oliveira, A1
Carvalho, VF1
d'Avila, JC1
Panizzutti, R1
Sierra-Paredes, G1
Loureiro, AI1
Wright, LC1
Sierra-Marcuño, G1
Soares-da-Silva, P1
Reese, SR1
Wilson, NA1
Huang, G1
Redfield, RR1
Zhong, W1
Djamali, A1
De Raadt, WM1
Wijnen, PA1
Bast, A1
Bekers, O1
Drent, M1
Ham, DJ1
Caldow, MK1
Chhen, V1
Chee, A1
Wang, X1
Proud, CG1
Lynch, GS1
Koopman, R1
Couce, ML1
Aldamiz-Echevarría, L1
Bueno, MA1
Barros, P1
Belanger-Quintana, A1
Blasco, J1
García-Silva, MT1
Márquez-Armenteros, AM1
Vitoria, I1
Vives, I1
Navarrete, R1
Fernández-Marmiesse, A1
Pérez, B1
Pérez-Cerdá, C1
Mikumo, H1
Yanagihara, T1
Hamada, N1
Harada, E1
Ogata-Suetsugu, S1
Ikeda-Harada, C1
Arimura-Omori, M1
Suzuki, K1
Yokoyama, T1
Nakanishi, Y1
Shingu, Y1
Shiiya, N1
Matsuzaki, K1
Kunihara, T1
Murashita, T1
Matsui, Y1
Imokawa, S2
Mori, K1
Harada, M1
Sagisaka, S1
Sano, T2
Uchiyama, H2
Yasuda, K2
Ukita, T1
Fujisawa, T1
Suda, T2
Chida, K2
Nishibe, T1
Kondo, Y1
Muto, A1
Dardik, A1
Ohara, Y1
Kainuma, M1
Takeda, K1
Shigemi, K1
Tsuneyoshi, Y1
Hamasu, K1
Han, L1
Hayamizu, K1
Denbow, DM1
Furuse, M1
Potrebić, O1
Jović-Stosić, J1
Vucinić, S1
Tadić, J1
Radulac, M1
Frizzo, JK1
Cardoso, MP1
de Assis, AM1
Perry, ML1
Volonté, C1
Frizzo, ME1
Li, XL1
An, Y1
Jin, QH1
Jin, YZ1
MacLeod, BA1
Wang, JT1
Chung, CC1
Ries, CR1
Schwarz, SK1
Puil, E1
Niino, T1
Hata, M1
Sezai, A1
Yoshitake, I1
Unosawa, S1
Fujita, K1
Shimura, K1
Osaka, S1
Minami, K1
Chiu, D1
Peterson, L1
Elkind, MSV1
Rosand, J1
Gerber, LM1
Silverstein, MD1
Ikegame, Y1
Yamashita, K1
Hayashi, S1
Yoshimura, S1
Nakashima, S1
Iwama, T1
Malhotra, RC1
Ghia, DK1
Cordato, DJ1
Beran, RG1
Moon, JM1
Chun, BJ1
Mise, M1
Miyazato, M1
Sugaya, K1
Nishijima, S1
Ashitomi, K1
Hatano, T1
Ogawa, Y1
Achong, DM2
Tenorio, LE1
Ameziane, N1
Beillat, T1
Verpillat, P1
Chollet-Martin, S1
Aumont, MC1
Seknadji, P1
Lamotte, M1
Lebret, D1
Ollivier, V1
de Prost, D1
Ishiguro, M1
Mikasa, S1
Otani, M1
Rundek, T1
Nielsen, K1
Phillips, S1
Johnston, KC1
Hux, M1
Watson, D1
Bhatia, M3
Wong, FL1
Fu, D1
Lau, HY1
Moochhala, SM2
Moore, PK2
Hagio, T1
Matsumoto, S1
Nakao, S1
Matsuoka, S1
Kawabata, K2
Todate, A1
Nagayama, M1
Enomoto, N2
Ryugo, M1
Sawa, Y1
Takano, H1
Matsumiya, G1
Iwai, S1
Ono, M1
Hata, H1
Yamauchi, T1
Nishimura, M1
Fujino, Y1
Matsuda, H1
Iba, T1
Kidokoro, A1
Fukunaga, M1
Takuhiro, K1
Yoshikawa, S1
Sugimotoa, K1
Anderson, S1
Shah, NP1
Zajick, D1
Cross, M1
Oates, ME1
Wu, JY1
Chang, SS1
Tseng, CP1
Deng, JF1
Lee, CC1
Gyurkocza, B1
Plescia, J1
Raskett, CM1
Garlick, DS1
Lowry, PA1
Carter, BZ1
Andreeff, M1
Meli, M1
Colombo, G1
Altieri, DC1
Furusawa, T1
Tsukioka, K1
Fukui, D1
Sakaguchi, M1
Seto, T1
Terasaki, T1
Wada, Y1
Amano, J1
Gundersen, Y1
Vaagenes, P1
Os, Ø1
Pillgram-Larsen, J1
Sundnes, KO1
Opstad, PK1
Nakamura, N1
Morisaki, H1
Suzuki, T1
Yajima, S1
Katori, N1
Kotake, Y1
Funakoshi, Y1
Yamada, S1
Ishizaka, A2
Takeda, J1
Nakamura, M1
Ogura, T1
Miyazawa, N1
Tagawa, A1
Kozawa, S1
Watanuki, Y1
Takahashi, H1
Endo, S1
Sato, N1
Yaegashi, Y1
Suzuki, Y1
Kojika, M1
Yamada, Y1
Yoshida, Y1
Nakadate, T1
Aoki, H1
Inoue, Y1
Hsiao, CT1
Lin, LJ1
Hsiao, KY1
Chou, MH1
Hsiao, SH1
Sidhapuriwala, JN1
Ng, SW1
Tamizhselvi, R2
Tanabe, M1
Takasu, K1
Yamaguchi, S1
Kodama, D1
Ono, H1
Bruinvels, J1
Pepplinkhuizen, L1
Zoch-Zwierz, W2
Rudobielska, M1
Levy, M1
Finestone, H1
Fechner, C1
Bonkowsky, HL2
Schady, W1
Zeman, RK1
Burrell, MI1
Cahow, CE1
Caride, V1
Skvortsova, VI3
Gusev, EI3
Komissarova, IA2
Kovalenko, AV3
Bolotov, DA1
Fidler, SM1
Fedorov, VN1
Haider, R1
Azad Khan, AK1
Roy, SK1
Dewan, N1
Alam, AN1
Mahalanabis, D1
Fink-Bennett, D2
Balon, HR1
Donati, G1
Spinazzè, R1
Sakamaki, F1
Urano, T1
Sayama, K1
Nakamura, H1
Terashima, T1
Waki, Y1
Tasaka, S1
Hasegawa, N1
Sato, K1
Nakagawa, N1
Obata, T1
Kanazawa, M1
Furuya, KN1
Durie, PR1
Roberts, EA1
Soldin, SJ1
Verjee, Z1
Yung-Jato, L1
Giesbrecht, E1
Ellis, L1
Alicicco, E1
Delfino, M1
Kleszczynski, D1
Oates, E1
Selland, DL1
Chin, CT1
Shih, WJ2
Lee, JK1
Magoun, S1
Wierzbinski, B1
Ryo, UY1
Lamont, AE1
Joyce, JM1
Grossman, SJ1
Chen, CC1
Holder, LE1
Maunoury, C1
Drachenberg, CI1
Kitamura, S1
Stryker, J1
Siegel, A1
Otoya, RE1
Seltzer, AM1
Donoso, AO1
Antman, EM1
Dambinova, SA1
Raevskiĭ, KS2
Alekseev, AA2
Bashkatova, VG1
Kudrin, VS2
Iakovleva, EV1
Malikova, LA1
Sokolov, MA1
Ogura, Y1
Krams, SM1
Martinez, OM1
Kopiwoda, S1
Higgins, JP1
Esquivel, CO1
Strauss, HW1
Tait, JF1
Blankenberg, FG1
Wheeler, MD1
Rose, ML1
Yamashima, S1
Seabra, V1
Madren, J1
Thurman, RG1
Serena, J1
Leira, R1
Castillo, J1
Pumar, JM1
Castellanos, M1
Dávalos, A1
Lankes, W1
Fleischer, K1
Gulba, DC1
Biasi, G1
Marcolongo, R1
Wienke, J1
Falen, S1
McCartney, W1
Kalimi, R1
Gecelter, GR1
Caplin, D1
Brickman, M1
Tronco, GT1
Love, C1
Yao, J1
Simms, HH1
Marini, CP1
Baumgartner, ER1
Bachmann, C2
Brechbühler, T2
Wick, H2
Chalabi, G1
Hino, M1
Nagatsu, T1
Kakumu, S1
Okuyama, S1
Yoshii, Y1
Nagatsu, I1
Marsano, L1
Mochizuki, T1
Charron, M1
Shah, AN1
Dobkin, J1
Tauxe, WN1
Bosman, DK1
Deutz, NE1
Maas, MA1
van Eijk, HM1
Smit, JJ1
de Haan, JG1
Chamuleau, RA1
Lee, YH1
Lee, WC1
Chen, MT1
Huang, JK1
Chung, C1
Chang, LS1
Kistler, AM1
Ziessman, HA1
Gooch, D1
Bitterman, P1
Shanley, DJ1
Buckner, AB1
Alexander, HG1
Balon, H1
Robbins, T1
Tsai, D1
Bhan, MK1
Sazawal, S1
Bhatnagar, S1
Bhandari, N1
Guha, DK1
Aggarwal, SK1
Hirata, M1
Nalin, DR1
Park, K1
Umaji, K1
Okumiya, T1
Nishida, M1
Sasaki, M1
Elsas, LJ1
Naglak, M1
Cook, GC1
Sapico, V1
Shear, L1
Litwack, G1
Chaput, JC1
Sol, C1
Garcia, B1
Perles, C1
Petite, JP1
Grivaux, M1
Housset, E1
Buxton, BH1
Stewart, DA1
Murray-Lyon, IM1
Curzon, G1
Williams, R1
Mihatsch, MJ1
Baumgartner, RE1
Bühler, UK1
Olafsson, A1
Ohnacker, H1
Kreimer-Birnbaum, M1
Mosovich, LL1
Bannerman, RM1
Woody, NC1
Snyder, CH1
Harris, JA1
Felig, P1
Brown, WV1
Levine, RA1
Klatskin, G1
Sharma, D1
Bhardwaj, SL1
Zefirov, YN1
Tarassov, OF1
Ghosh, S1
Cüppers, H1
Bloomer, JR1
Berk, PD1
Stein, JA1
Berlin, NI1
Tschudy, DP1
Björnesjö, KB2
Jarnulf, B1
Lausing, E1
Shanbrom, E1
Thelin, GM1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Perioperative Application of Sivelestat Sodium in Acute Type A Aortic Dissection Patients With Preoperative Moderate to Severe Hypoxemia to Shorten the Duration of Postoperative Invasive Mechanical Ventilation[NCT05874700]30 participants (Anticipated)Interventional2023-05-31Not yet recruiting
Controlled and Randomized Clinical Trial for Evaluating the Effect of a Supplement of Glycine as Adjuvant in the Treatment of COVID-19 Pneumonia in Patients Initiating Mechanical Ventilation[NCT04443673]59 participants (Actual)Interventional2020-06-15Terminated (stopped due to An interim analysis showed no difference in major outcomes (n=35 glycine and n=24 control participants))
Evaluation of the Capability of a Glycine Oral Supplement for Diminishing Bronchial Inflammation in Children With Cystic Fibrosis[NCT01417481]Phase 213 participants (Actual)Interventional2012-03-31Terminated (stopped due to Some of the researchers finished their participation in the study.)
Comparison of Two Antalgic Strategies: Acupuncture Versus Intravenous Morphine in the Management of Acute Pain in Emergency Departement. A Randomized Trial of Efficacy and Safety[NCT02152410]Early Phase 1100 participants (Actual)Interventional2012-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Changes in Serum Concentration of Inflammatory Biomarkers (TNF-alpha)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentages were log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

Interventionlog (percent change) (Mean)
Glycine-0.3908
Placebo0.2035

Changes in Sputum Concentration of Inflammatory Biomarkers (G-CSF)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentage change was log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

Interventionlog (percent change) (Mean)
Glycine-0.0819
Placebo0.1668

Changes in Sputum Concentration of Inflammatory Biomarkers (IL-6)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentage change was log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

Interventionlog (percent change) (Mean)
Glycine-0.00007
Placebo0.1739

Changes in Clinical Data Scores (Other Than Sputum Production, Dyspnea and Global Symptoms)

"To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]).~Each respiratory symptom (Cough severity, Sputum features, Appetite, Dyspnea, and Energy perception) was evaluated in a 5-options Likert scale, ranging from 1 (better) to 5 (worse). The total score was computed by the simple sum of the five symptoms." (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Cough questionnaire scoreAppetite questionnaire scoreEnergy questionnaire scoreBody weightHeightHeart rateRespiratory rateTemperature
Glycine81.189.184.6101.6100.5103.594.8100.0
Placebo89.1132.1111.5103.6100.598.1109.0100.1

Changes in FEV1, FEF25, and FEFmax

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Forced expiratory volume at first second (FEV1)Forced expiratory flow at 25%FVC (FEF25)Maximal forced expiratory flow (FEFmax, PEFR)
Glycine109.7133.9115.3
Placebo91.483.391.2

Changes in Other Spirometric Variables

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Forced vital capacity (FVC)Forced expiratory flow at 75%FVC (FEF75)
Glycine104.1111.8
Placebo100.6108.9

Changes in Pulse Oximetry, FEV1/FVC, and FEF50.

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Peripheral oxygen saturation (SpO2)FEV1/FVCForced expiratory flow at 50%FVC (FEF50)
Glycine105.2105.2115.5
Placebo98.994.993.1

Changes in Score for Sputum Production, Dyspnea and Global Symptoms

"To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]).~In the symptoms questionnaire, each respiratory symptom (Cough severity, Sputum features, Appetite, Dyspnea, and Energy perception) was evaluated in a 5-options Likert scale, ranging from 1 (better) to 5 (worse). The total score was computed by the simple sum of the five symptoms." (NCT01417481)
Timeframe: 8 weeks

,
InterventionPercentage of baseline (Mean)
Sputum questionnaire scoreDyspnea questionnaire scoreTotal questionnaire score
Glycine82.075.677.7
Placebo102.6103.898.7

Changes in Serum Concentration of Inflammatory Biomarkers (Other Than TNF-alpha)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentages were log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

,
Interventionlog (percent change) (Mean)
MyeloperoxidaseIL-1IL-4IL-6IL-7IL-8IL-12IL-13G-CSFIFN-gammaMCP-1MIP-1beta
Glycine-0.4361-0.16350.29640.00850.0356-0.14660.3203-0.0561-0.07760.3272-0.08360.0330
Placebo-0.2906-0.03520.14700.22550.0819-0.23640.26030.19530.22720.36390.0472-0.0608

Changes in Sputum Concentration of Inflammatory Biomarkers (Other Than IL-6 and G-CSF)

To correct for the baseline variability, all measurements were expressed as percentage of baseline (value at week 8 with respect to baseline value [beginning of the glycine or placebo period, respectively]). Then, percentage change was log-transformed to adjust to a normal distribution. (NCT01417481)
Timeframe: 8 weeks

,
Interventionlog (percent change) (Mean)
MyeloperoxidaseIL-1IL-2IL-4IL-5IL-7IL-8IL-10IL-12IL-13IL-17IFN-gammaMCP-1MIP-1betaTNF-alphaGM-CSF
Glycine0.1294-0.09180.0233-0.01610.24980.0611-0.08240.05490.16750.16300.06800.02480.0042-0.03030.0412-0.0538
Placebo0.0669-0.0102-0.02740.05220.13040.13870.05420.00740.06770.09530.11400.06490.26080.09770.1568-0.0822

Reviews

4 reviews available for glycine and Acute Disease

ArticleYear
Neurologic manifestations of acute porphyria.
    Seminars in liver disease, 1982, Volume: 2, Issue:2

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology;

1982
The role of morphine-augmented cholescintigraphy in the detection of acute cholecystitis.
    Clinical nuclear medicine, 1993, Volume: 18, Issue:10

    Topics: Acute Disease; Aniline Compounds; Cholecystitis; Glycine; Humans; Imino Acids; Morphine; Organotechn

1993
[Pathophysiology of acute lung injury].
    Nihon Kyobu Shikkan Gakkai zasshi, 1996, Volume: 34 Suppl

    Topics: Acute Disease; Animals; Biomarkers; Capillary Permeability; Cell Adhesion Molecules; Clinical Trials

1996
[Direct thrombin antagonists].
    Herz, 2001, Volume: 26 Suppl 1

    Topics: Acute Disease; Angina, Unstable; Angioplasty, Balloon, Coronary; Animals; Anticoagulants; Antithromb

2001

Trials

16 trials available for glycine and Acute Disease

ArticleYear
[Effect of sivelestat sodium on acute lung injury after acute aortic dissection].
    Kyobu geka. The Japanese journal of thoracic surgery, 2008, Volume: 61, Issue:6

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aortic Aneurysm; Aortic Dissection; Female; Glycine;

2008
Comparison of outcomes after intracerebral hemorrhage and ischemic stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2010, Volume: 19, Issue:3

    Topics: Acute Disease; Aged; Brain Ischemia; Cerebral Hemorrhage; Cohort Studies; Disability Evaluation; Dou

2010
Health care resource use after acute stroke in the Glycine Antagonist in Neuroprotection (GAIN) Americas trial.
    Stroke, 2004, Volume: 35, Issue:6

    Topics: Acute Disease; Aftercare; Aged; Canada; Female; Glycine; Glycine Agents; Health Resources; Humans; I

2004
Effect of a polymorphonuclear elastase inhibitor (sivelestat sodium) on acute lung injury after cardiopulmonary bypass: findings of a double-blind randomized study.
    Surgery today, 2006, Volume: 36, Issue:4

    Topics: Acute Disease; Aged; Cardiopulmonary Bypass; Female; Glycine; Humans; Interleukin-8; Leukocyte Elast

2006
Capacity of glycine to modulate early inflammatory disturbances after serious gunshot injuries in the pig.
    Scandinavian journal of clinical and laboratory investigation, 2007, Volume: 67, Issue:2

    Topics: Acute Disease; Animals; Blood Pressure; Cytokines; Glutathione; Glycine; Glycine Agents; Heart Rate;

2007
Sivelestat sodium hydrate improves septic acute lung injury by reducing alveolar dysfunction.
    Research communications in molecular pathology and pharmacology, 2006, Volume: 119, Issue:1-6

    Topics: Acute Disease; Adolescent; Adult; Aged; Glycine; Humans; Interleukin-8; Leukocyte Elastase; Leukocyt

2006
[A comprehensive clinico-neurophysiological study of the efficacy of the pharmaceutical preparation glycine in acute ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1995, Volume: 95, Issue:1

    Topics: Acute Disease; Aged; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Double-Blind Method; F

1995
Management of acute diarrhoea in diabetic patients using oral rehydration solutions containing glucose, rice, or glycine.
    BMJ (Clinical research ed.), 1994, Mar-05, Volume: 308, Issue:6929

    Topics: Acute Disease; Adolescent; Adult; Blood Glucose; Defecation; Diabetes Complications; Diarrhea; Femal

1994
[A clinical study to determine the optimal dosage of ST-679 in the treatment of rheumatic diseases].
    La Clinica terapeutica, 1993, Volume: 142, Issue:1 Pt 2

    Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Dist

1993
[Clinical trial comparing a new NSAID with 2 different dosages and diclofenac in patients with arthralgia in acute phase].
    La Clinica terapeutica, 1995, Volume: 146, Issue:10

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Drug Administration Sched

1995
[Neuroprotective effects of glycine in the acute period of ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1999, Volume: 99, Issue:2

    Topics: Acute Disease; Administration, Sublingual; Adult; Aged; Autoantibodies; Brain Ischemia; Double-Blind

1999
Neurological deterioration in acute lacunar infarctions: the role of excitatory and inhibitory neurotransmitters.
    Stroke, 2001, Volume: 32, Issue:5

    Topics: Acute Disease; Aged; Brain Infarction; Disease Progression; Female; gamma-Aminobutyric Acid; Glutami

2001
[Efficacy and safety of amtolmetin guacyl in the treatment of acute osteoarthritis].
    Minerva medica, 2001, Volume: 92, Issue:5

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; Foll

2001
Acupuncture in the treatment of renal colic.
    The Journal of urology, 1992, Volume: 147, Issue:1

    Topics: Acupuncture Therapy; Acute Disease; Adult; Analgesics; Colic; Dipyrone; Drug Combinations; Female; G

1992
Comparison of glucose/electrolyte and maltodextrin/glycine/glycyl-glycine/electrolyte oral rehydration solutions in acute diarrhea in children.
    Journal of pediatric gastroenterology and nutrition, 1991, Volume: 13, Issue:4

    Topics: Acute Disease; Breast Feeding; Child, Preschool; Citrates; Defecation; Diarrhea; Diarrhea, Infantile

1991
Glycine, glycyl-glycine and maltodextrin based oral rehydration solution. Assessment of efficacy and safety in comparison to standard ORS.
    Acta paediatrica Scandinavica, 1990, Volume: 79, Issue:5

    Topics: Acute Disease; Child, Preschool; Dehydration; Double-Blind Method; Fluid Therapy; Gastroenteritis; G

1990

Other Studies

89 other studies available for glycine and Acute Disease

ArticleYear
REV-ERBα Agonist GSK4112 attenuates Fas-induced Acute Hepatic Damage in Mice.
    International journal of medical sciences, 2021, Volume: 18, Issue:16

    Topics: Acute Disease; Animals; Antibodies; Apoptosis; Chemical and Drug Induced Liver Injury; Circadian Rhy

2021
Acute leukemias in 2020: state of the art.
    Minerva medica, 2020, Volume: 111, Issue:5

    Topics: Acute Disease; Aminopyridines; Antineoplastic Agents; Antineoplastic Agents, Immunological; Congress

2020
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.
    The Journal of experimental medicine, 2021, 05-03, Volume: 218, Issue:5

    Topics: Acute Disease; Aminopyridines; Animals; Cell Line, Tumor; Doxycycline; Drug Resistance, Neoplasm; En

2021
Methylenecyclopropyl glycine, not pesticide exposure as the primary etiological factor underlying hypoglycemic encephalopathy in Muzaffarpur, India.
    Toxicology letters, 2019, Volume: 301

    Topics: Acute Disease; Acute Febrile Encephalopathy; Animals; Cyclopropanes; DDT; Disease Models, Animal; Fr

2019
A neonatal case of 3-hydroxy-3-methylglutaric-coenzyme A lyase deficiency.
    Italian journal of pediatrics, 2013, May-24, Volume: 39

    Topics: Acetyl-CoA C-Acetyltransferase; Acidosis; Acute Disease; Amino Acid Metabolism, Inborn Errors; Gluta

2013
Combined effects of sivelestat and resveratrol on severe acute pancreatitis-associated lung injury in rats.
    Experimental lung research, 2014, Volume: 40, Issue:6

    Topics: Acute Disease; Amylases; Animals; Arterial Pressure; Bronchoalveolar Lavage Fluid; Glycine; Interleu

2014
D-serine prevents cognitive deficits induced by acute stress.
    Neuropharmacology, 2014, Volume: 86

    Topics: Acute Disease; Animals; Cognition Disorders; Corticosterone; Disease Models, Animal; Glycine; Hippoc

2014
Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus.
    BMC neuroscience, 2014, Dec-20, Volume: 15

    Topics: Acute Disease; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bridged Bicyclo Compounds, Hete

2014
Calcineurin Inhibitor Minimization With Ixazomib, an Investigational Proteasome Inhibitor, for the Prevention of Antibody Mediated Rejection in a Preclinical Model.
    Transplantation, 2015, Volume: 99, Issue:9

    Topics: Acute Disease; Animals; B-Lymphocytes; Biomarkers; Boron Compounds; Calcineurin Inhibitors; Cyclospo

2015
Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure.
    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2015, Jul-22, Volume: 32, Issue:2

    Topics: Acute Disease; Adult; Bronchoalveolar Lavage Fluid; Environmental Exposure; Female; Glycine; Glyphos

2015
Glycine restores the anabolic response to leucine in a mouse model of acute inflammation.
    American journal of physiology. Endocrinology and metabolism, 2016, 06-01, Volume: 310, Issue:11

    Topics: Acute Disease; Anabolic Agents; Animals; Dose-Response Relationship, Drug; Drug Resistance; Drug Syn

2016
Genotype and phenotype characterization in a Spanish cohort with isovaleric acidemia.
    Journal of human genetics, 2017, Volume: 62, Issue:3

    Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Asymptomatic Diseases; Carnitine; Child; Child,

2017
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib-naphthalene-induced acute pneumonitis in mice.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Female; Gefitinib; Glycine; Humans; Kaplan-Mei

2017
[Acute respiratory failure due to pneumocystis pneumonia successfully treated with combined use of sivelestat sodium hydrate].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2008, Volume: 46, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Drug Therapy, Combination; Ganciclovir; Gl

2008
Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study.
    The Journal of cardiovascular surgery, 2008, Volume: 49, Issue:5

    Topics: Acute Disease; Analysis of Variance; Aortic Aneurysm, Thoracic; Aortic Dissection; Cardiopulmonary B

2008
l-Serine induces sedative and hypnotic effects acting at GABA(A) receptors in neonatal chicks.
    European journal of pharmacology, 2008, Dec-03, Volume: 599, Issue:1-3

    Topics: Acute Disease; Animals; Animals, Newborn; Chickens; Disease Models, Animal; Glycine; Hypnotics and S

2008
[Acute glyphosate-surfactant poisoning with neurological sequels and fatal outcome].
    Vojnosanitetski pregled, 2009, Volume: 66, Issue:9

    Topics: Acute Disease; Akinetic Mutism; Fatal Outcome; Female; Glycine; Glyphosate; Herbicides; Humans; Midd

2009
Effects of acute perinatal asphyxia in the rat hippocampus.
    Cellular and molecular neurobiology, 2010, Volume: 30, Issue:5

    Topics: Acute Disease; Animals; Animals, Newborn; Asphyxia; Biological Transport; Cell Survival; Female; Glu

2010
[Changes of gamma-aminobutyric acid and glycine released in the medial vestibular nucleus following acute hypotension in conscious rats].
    Sheng li xue bao : [Acta physiologica Sinica], 2010, Feb-25, Volume: 62, Issue:1

    Topics: Acute Disease; Animals; Chromatography, High Pressure Liquid; Ear, Inner; gamma-Aminobutyric Acid; G

2010
Analgesic properties of the novel amino acid, isovaline.
    Anesthesia and analgesia, 2010, Apr-01, Volume: 110, Issue:4

    Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; beta-Alanine; Chronic Disease; Cisterna Magna; Fem

2010
Efficacy of neutrophil elastase inhibitor on type A acute aortic dissection.
    The Thoracic and cardiovascular surgeon, 2010, Volume: 58, Issue:3

    Topics: Acute Disease; Aged; Antithrombin III; Aortic Aneurysm; Aortic Dissection; Blood Vessel Prosthesis I

2010
Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:7

    Topics: Acute Disease; Angiopoietin-1; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Ce

2010
Glyphosate-surfactant herbicide-induced reversible encephalopathy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:11

    Topics: Acidosis; Acute Disease; Aged; Coma; Glasgow Coma Scale; Glycine; Glyphosate; Herbicides; Humans; Ma

2010
Predicting acute complicated glyphosate intoxication in the emergency department.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:7

    Topics: Acute Disease; Adult; Age Factors; Aged; Alanine Transaminase; Emergency Service, Hospital; Female;

2010
[Epidemiological study of glyphosate herbicide poisoning].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2011, Volume: 24, Issue:1

    Topics: Accidents; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Femal

2011
Inhibitory effect of intrathecal glycine on the micturition reflex in normal and spinal cord injury rats.
    Experimental neurology, 2003, Volume: 183, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Female; Glutamic Acid; Glycine; Gly

2003
Early morphine administration to expedite gallbladder visualization during cholescintigraphy for acute cholecystitis.
    Clinical nuclear medicine, 2003, Volume: 28, Issue:9

    Topics: Acute Disease; Aniline Compounds; Cholecystitis; Female; Gallbladder; Glycine; Humans; Imino Acids;

2003
Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Volume: 23, Issue:12

    Topics: Acute Disease; Adult; Aged; Alleles; Amino Acid Substitution; Aspartic Acid; Case-Control Studies; C

2003
[A case of acute poisoning caused by the inhalation of a nonselective herbicide REBIN GT SC (butafenacil and glyphosate isopropylamine)].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2004, Volume: 17, Issue:1

    Topics: Acute Disease; Aged; Cysteine; Drug Combinations; Fluid Therapy; Glutathione; Glycine; Glyphosate; H

2004
Role of hydrogen sulfide in acute pancreatitis and associated lung injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:6

    Topics: Acute Disease; Alkynes; Amylases; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; C

2005
Sivelestat, a specific neutrophil elastase inhibitor, prevented phorbol myristate acetate-induced acute lung injury in conscious rabbits.
    Pulmonary pharmacology & therapeutics, 2005, Volume: 18, Issue:4

    Topics: Acute Disease; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug;

2005
[Two cases of acute respiratory failure due to idiopathic interstitial pneumonia successfully treated with sivelestat sodium hydrate and steroid therapy].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:1

    Topics: Acute Disease; Aged; Drug Therapy, Combination; Female; Glycine; Humans; Lung Diseases, Interstitial

2006
Pretreatment of sivelestat sodium hydrate improves the lung microcirculation and alveolar damage in lipopolysaccharide-induced acute lung inflammation in hamsters.
    Shock (Augusta, Ga.), 2006, Volume: 26, Issue:1

    Topics: Acute Disease; Animals; Cricetinae; Glycine; Leukocyte Elastase; Lipopolysaccharides; Male; Microcir

2006
A positional maneuver to augment conventional cholescintigraphy in the evaluation of acute acalculous cholecystitis.
    Clinical nuclear medicine, 2006, Volume: 31, Issue:7

    Topics: Abdominal Pain; Acalculous Cholecystitis; Acute Disease; Aniline Compounds; Fever; Gallbladder; Glyc

2006
Parenteral glyphosate-surfactant herbicide intoxication.
    The American journal of emergency medicine, 2006, Volume: 24, Issue:4

    Topics: Acute Disease; Adult; Glycine; Glyphosate; Hemolysis; Herbicides; Humans; Injections, Intravenous; M

2006
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
    Journal of the National Cancer Institute, 2006, Aug-02, Volume: 98, Issue:15

    Topics: Acute Disease; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell

2006
The effects of a neutrophil elastase inhibitor on the postoperative respiratory failure of acute aortic dissection.
    The Thoracic and cardiovascular surgeon, 2006, Volume: 54, Issue:6

    Topics: Acute Disease; Aged; Aortic Aneurysm; Aortic Dissection; Cardiopulmonary Bypass; Female; Glycine; Hu

2006
Inhibition of neutrophil elastase attenuates gut mucosal injury evoked by acute alveolar hypoxia in rabbits.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:1

    Topics: Acute Disease; Animals; Glycine; HMGB1 Protein; Hypoxia; Intestinal Mucosa; Leukocyte Elastase; Male

2007
[Outcome of patients with acute exacerbation of idiopathic interstitial fibrosis (IPF) treated with sivelestat and the prognostic value of serum KL-6 and surfactant protein D].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2007, Volume: 45, Issue:6

    Topics: Acute Disease; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers; Chronic Disease; Disease Pro

2007
Acute pancreatitis caused by severe glyphosate-surfactant oral intoxication.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:3

    Topics: Acute Disease; Aged, 80 and over; Glycine; Glyphosate; Herbicides; Humans; Male; Pancreatitis; Paren

2008
Pro-inflammatory effects of hydrogen sulphide on substance P in caerulein-induced acute pancreatitis.
    Journal of cellular and molecular medicine, 2008, Volume: 12, Issue:2

    Topics: Acute Disease; Alkynes; Animals; Ceruletide; Cystathionine beta-Synthase; Glycine; Hydrogen Sulfide;

2008
Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment.
    Anesthesiology, 2008, Volume: 108, Issue:5

    Topics: Acute Disease; Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glycine;

2008
Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury.
    Pancreas, 2008, Volume: 36, Issue:4

    Topics: Acute Disease; Alkynes; Animals; Ceruletide; Chemokine CCL5; Chemokines; Cystathionine gamma-Lyase;

2008
Impaired glycine-serine conversion and increased plasma taurine levels in episodic psychotic patients with psychedelic symptoms.
    Journal of psychiatric research, 1984, Volume: 18, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acute Disease; Adult; Female; Glycine; Ha

1984
[Glycine transamidinase (ADT) activity in the serum and urine of children with lipoid nephrosis].
    Pediatria polska, 1983, Volume: 58, Issue:7

    Topics: Acute Disease; Amidinotransferases; Child; Child, Preschool; Convalescence; Enzyme Activation; Glyci

1983
Action of renal vasodilators in dogs following acute biliary obstruction.
    The Journal of surgical research, 1984, Volume: 36, Issue:2

    Topics: Acetylcholine; Acute Disease; Angiotensin II; Animals; Bile; Bradykinin; Cholestasis; Diuresis; Dogs

1984
[Glycine amidinotransferase activity of the blood and urine of children with acute streptococcal glomerulonephritis].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Dec-06, Volume: 37, Issue:48

    Topics: Acute Disease; Adolescent; Amidinotransferases; Child; Child, Preschool; Glomerulonephritis; Glycine

1982
Diagnostic utility of cholescintigraphy and ultrasonography in acute cholecystitis.
    American journal of surgery, 1981, Volume: 141, Issue:4

    Topics: Acute Disease; Adult; Aged; Chemical Phenomena; Chemistry; Cholecystitis; Cholelithiasis; Chronic Di

1981
Effect of a specific neutrophil elastase inhibitor, ONO-5046, on endotoxin-induced acute lung injury.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:1

    Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Chemotaxis; Escherichia coli; Glyc

1996
Glycine conjugation of para-aminobenzoic acid (PABA): a quantitative test of liver function.
    Clinical biochemistry, 1995, Volume: 28, Issue:5

    Topics: 4-Aminobenzoic Acid; Acute Disease; Adolescent; Aminohippuric Acids; Child; Child, Preschool; Chroni

1995
Gallbladder nonvisualization with pericholecystic rim sign: morphine-augmentation optimizes diagnosis of acute cholecystitis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:2

    Topics: Acute Disease; Aniline Compounds; Case-Control Studies; Cholecystitis; Chronic Disease; False Positi

1996
Morphine-augmented cholescintigraphy enhances duodenogastric reflux.
    Annals of nuclear medicine, 1995, Volume: 9, Issue:4

    Topics: Acute Disease; Aniline Compounds; Cholecystitis; Chronic Disease; Duodenogastric Reflux; Evaluation

1995
Acute cholecystitis detected on a Tc-99m sestamibi myocardial imaging.
    Clinical nuclear medicine, 1996, Volume: 21, Issue:11

    Topics: Acute Disease; Adult; Aniline Compounds; Cholecystitis; Gallbladder; Glycine; Heart; Humans; Imino A

1996
Morphine augmentation increases gallbladder visualization in patients pretreated with cholecystokinin.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aniline Compounds; Cholecystitis; Cholecy

1997
Abdominal aortic aneurysm visualized with hepatobiliary scintigraphy.
    Clinical nuclear medicine, 1997, Volume: 22, Issue:9

    Topics: Acute Disease; Aged; Aniline Compounds; Aortic Aneurysm, Abdominal; Bile Ducts, Intrahepatic; Cholec

1997
Acute and long-lasting effects of neonatal hypoxia on (+)-3-[125I]MK-801 binding to NMDA brain receptors.
    Experimental neurology, 1997, Volume: 148, Issue:1

    Topics: Acute Disease; Animals; Animals, Newborn; Brain Chemistry; Brain Damage, Chronic; Dizocilpine Maleat

1997
Another chapter of the antithrombin story has been written...
    European heart journal, 1997, Volume: 18, Issue:9

    Topics: Acute Disease; Antithrombins; Coronary Disease; Glycine; Heparin; Hirudin Therapy; Humans; Piperidin

1997
[Levels of neurotransmitter amino acids in the cerebrospinal fluid of patients with acute ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1999, Volume: 99, Issue:2

    Topics: Acute Disease; Aspartic Acid; Brain Ischemia; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycin

1999
Radiolabeled annexin V imaging: diagnosis of allograft rejection in an experimental rodent model of liver transplantation.
    Radiology, 2000, Volume: 214, Issue:3

    Topics: Acute Disease; Aniline Compounds; Animals; Annexin A5; Glycine; Graft Rejection; Imino Acids; Liver;

2000
Dietary glycine blunts lung inflammatory cell influx following acute endotoxin.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:2

    Topics: Acute Disease; Animals; Calcium; Cells, Cultured; Dietary Supplements; Drug Administration Schedule;

2000
Dietary glycine blunts lung inflammatory cell influx following acute endotoxin.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:2

    Topics: Acute Disease; Animals; Calcium; Cells, Cultured; Dietary Supplements; Drug Administration Schedule;

2000
Dietary glycine blunts lung inflammatory cell influx following acute endotoxin.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:2

    Topics: Acute Disease; Animals; Calcium; Cells, Cultured; Dietary Supplements; Drug Administration Schedule;

2000
Dietary glycine blunts lung inflammatory cell influx following acute endotoxin.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:2

    Topics: Acute Disease; Animals; Calcium; Cells, Cultured; Dietary Supplements; Drug Administration Schedule;

2000
Hepatobiliary scan showing type II choledochal cyst.
    Clinical nuclear medicine, 2001, Volume: 26, Issue:12

    Topics: Acute Disease; Aniline Compounds; Cholecystitis; Choledochal Cyst; Female; Glycine; Humans; Imino Ac

2001
Diagnosis of acute cholecystitis: sensitivity of sonography, cholescintigraphy, and combined sonography-cholescintigraphy.
    Journal of the American College of Surgeons, 2001, Volume: 193, Issue:6

    Topics: Acute Disease; Adult; Aged; Aniline Compounds; Cholecystectomy, Laparoscopic; Cholecystitis; Choleli

2001
Acute neonatal nonketotic hyperglycinemia: normal propionate and methylmalonate metabolism.
    Pediatric research, 1975, Volume: 9, Issue:7

    Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Coenzyme A; Female; Fi

1975
[Stosstherapy with steroid-containing combination preparation "Ambene" in the acute stages of rheumatic diseases].
    MMW, Munchener medizinische Wochenschrift, 1975, Mar-07, Volume: 117, Issue:10

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aluminum; Aminopyrine; Anti-Inflammato

1975
Glycylprolyl beta-naphthylamidase activity in human serum.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Jul-09, Volume: 62, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferas

1975
Cholescintigraphic demonstration of transient and functional common bile duct obstruction in a patient with acute pancreatitis.
    Bildgebung = Imaging, 1992, Volume: 59, Issue:1

    Topics: Acute Disease; Aged; Aniline Compounds; Cholestasis, Extrahepatic; Common Bile Duct Diseases; Diagno

1992
Hepatobiliary imaging in acute alcoholic hepatitis with fatty liver.
    Clinical nuclear medicine, 1992, Volume: 17, Issue:3

    Topics: Acute Disease; Adult; Aniline Compounds; Fatty Liver; Female; Glycine; Hepatitis, Alcoholic; Humans;

1992
Amino acid release from cerebral cortex in experimental acute liver failure, studied by in vivo cerebral cortex microdialysis.
    Journal of neurochemistry, 1992, Volume: 59, Issue:2

    Topics: Acute Disease; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Dialysis; gamma-Aminobutyric Ac

1992
Morphine-augmented cholescintigraphy in acute cholecystitis. A satisfactory alternative to delayed imaging.
    Clinical nuclear medicine, 1991, Volume: 16, Issue:6

    Topics: Acute Disease; Aniline Compounds; Cholecystitis; Fasting; Female; Gallbladder; Glycine; Humans; Imin

1991
The scintigraphic "duodenal cut off sign" in acute pancreatitis.
    Clinical nuclear medicine, 1991, Volume: 16, Issue:4

    Topics: Acute Disease; Adult; Aniline Compounds; Duodenum; Female; Glycine; Humans; Imino Acids; Organotechn

1991
Morphine-augmented cholescintigraphy: its efficacy in detecting acute cholecystitis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:6

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aniline Compounds; Cholecystitis; Female; Glycine; Hu

1991
[Study of impaired metabolism of guanidinoacetic acid in uremia--the compensatory role of the pancreas in guanidinoacetic acid synthesis].
    Nihon Jinzo Gakkai shi, 1989, Volume: 31, Issue:9

    Topics: Acute Disease; Animals; Diabetes Mellitus, Experimental; Ethionine; Glycine; Insulin; Male; Pancreas

1989
Comparison of oral rehydration solutions.
    Journal of pediatric gastroenterology and nutrition, 1989, Volume: 8, Issue:2

    Topics: Acute Disease; Diarrhea; Fluid Therapy; Food, Formulated; Glycine; Humans; Malabsorption Syndromes

1989
[Guanidino compounds in liver diseases--clinical evaluation of guanidino acetic acid in acute hepatic failure].
    Rinsho byori. The Japanese journal of clinical pathology, 1989, Volume: 37, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Biomarkers; Child; Child, Preschool; Female; Glycine; Hepati

1989
Acute and chronic-intermittent isovaleric acidemia: diagnosis and glycine therapy.
    Acta paediatrica Japonica : Overseas edition, 1988, Volume: 30, Issue:4

    Topics: Acute Disease; Child; Child, Preschool; Chronic Disease; Female; Glycine; Hemiterpenes; Humans; Isov

1988
Increased glycine absorption rate associated with acute bacterial infections in man.
    The British journal of nutrition, 1973, Volume: 29, Issue:3

    Topics: Acute Disease; Adult; Chronic Disease; gamma-Globulins; Glycine; Hemoglobinometry; Humans; Intestina

1973
Translocation of inducible tyrosine aminotransferase to the mitochondrial fraction. Facilitation by acute uremia and other conditions.
    The Journal of biological chemistry, 1974, Apr-10, Volume: 249, Issue:7

    Topics: Acute Disease; Animals; Antigen-Antibody Reactions; Aspartate Aminotransferases; Biological Transpor

1974
[Acute intermittent porphyria associated with Biermer's anemia. Value of the glycocoll test].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Dec-26, Volume: 48, Issue:53

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Anemia, Pernicious; Feces; Female; Genes, Domina

1972
Plasma amino acids in experimental acute hepatic failure and their relationship to brain tryptophan.
    Clinical science and molecular medicine, 1974, Volume: 46, Issue:4

    Topics: Acute Disease; Alanine; Amino Acids; Animals; Brain Chemistry; Disease Models, Animal; Glycine; Hepa

1974
[Non-ketotic hyperglycinemia: peracute course in neonatal period].
    Helvetica paediatrica acta, 1971, Volume: 26, Issue:3

    Topics: Acute Disease; Amino Acids; Biopsy; Brain; Cerebellum; Fatty Liver; Glycine; Hiccup; Humans; Infant,

1971
Acute intermittent porphyria. A clinical, biochemical and family study.
    Journal of medicine, 1971, Volume: 2, Issue:3

    Topics: Acetone; Acute Disease; Adenosine Monophosphate; Child, Preschool; Glycine; Humans; Injections, Intr

1971
Hyperprolinemia: clinical and biochemical family study.
    Pediatrics, 1969, Volume: 44, Issue:4

    Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Brain; Bronchopneumonia; Central Nervous System

1969
Glucose homeostasis in viral hepatitis.
    The New England journal of medicine, 1970, Dec-24, Volume: 283, Issue:26

    Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Biopsy; Blood Glucose; Dietary Carbohydrates

1970
Acute intermittent porphyria.
    Indian pediatrics, 1970, Volume: 7, Issue:7

    Topics: Acute Disease; Child; Coenzyme A; Female; Glycine; Humans; Male; Pedigree; Porphyrias; Porphyrins

1970
[Ciloprin cum anesthetico. Clinical and ambulatory therapy in inflammatory ear diseases].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1970, Aug-11, Volume: 59, Issue:32

    Topics: Acute Disease; Ear Diseases; Glycine; Humans; Otitis Externa; Otitis Media; Sulfonamides

1970
Blood volume and bilirubin production in acute intermittent porphyria.
    The New England journal of medicine, 1971, Jan-07, Volume: 284, Issue:1

    Topics: Acute Disease; Bilirubin; Blood Volume; Carbon Isotopes; Chromium Isotopes; Erythrocyte Aging; Eryth

1971
The erythrocyte plasma distribution of amino acids in health and disease.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 20, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronc

1968
Uptake of labelled amino acids into human erythrocytes in disease.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 20, Issue:1

    Topics: Acute Disease; Alanine; Amino Acids; Anemia; Bronchitis; Bronchopneumonia; Carbon Isotopes; Erythroc

1968
Experimental prophylaxis of severe hemophilia with a factor VIII concentrate.
    JAMA, 1969, Jun-09, Volume: 208, Issue:10

    Topics: Acute Disease; Adult; Blood Pressure; Chemical Precipitation; Factor VIII; Fibrinogen; Glycine; Hemo

1969