glyceryl-2-arachidonate has been researched along with Pancreatic-Neoplasms* in 1 studies
1 other study(ies) available for glyceryl-2-arachidonate and Pancreatic-Neoplasms
| Article | Year |
|---|---|
The role of 2-arachidonoylglycerol in the regulation of the tumor-immune microenvironment in murine models of pancreatic cancer.
The pancreatic ductal adenocarcinoma (PDAC) microenvironment plays a critical role in the antitumor immune response. 2-arachidonoylglycerol (2-AG) exhibits a direct antitumor effect in various tumor models. However, the immunomodulatory effect of 2-AG on PDAC remains obscure. The aim of this study was to explore the tumor microenvironment response to 2-AG in pancreatic cancer. A PDAC orthotopic tumor model was used to investigate tumor proliferation and the population of immune cells in vivo, including dendritic cells (DCs), myeloid-derived suppressor cells (MDSCs), CD8 Topics: Animals; Arachidonic Acids; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cytokines; Dendritic Cells; Endocannabinoids; Female; Glycerides; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells; Pancreatic Neoplasms; Tumor Microenvironment | 2019 |