glycerophosphoinositol 4,5-bisphosphate and Disease Models, Animal

Topics: Actins; Animals; Bacterial Proteins; Cell Surface Extensions; Colon; Disease Models, Animal; Dysentery, Bacillary; Host-Pathogen Interactions; HT29 Cells; Humans; Phosphatidylinositol 4,5-Diphosphate; Phosphoric Monoester Hydrolases; Rabbits; Shigella flexneri; Type III Secretion Systems

Topics: Animals; beta-Arrestin 2; Cardiomegaly; Carvedilol; Cytokines; Diet, High-Fat; Dietary Sugars; Disease Models, Animal; Fibrosis; Fructose; Insulin Resistance; Male; Mice; Myocytes, Cardiac; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Ventricular Function, Left; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Cerebral Small Vessel Diseases; Cerebrovascular Circulation; Disease Models, Animal; Endothelial Cells; Hyperemia; Male; Mice, Transgenic; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels, Inwardly Rectifying

Topics: Animals; Apoptosis; Atenolol; beta-Arrestin 2; Blood Pressure; Cardio-Renal Syndrome; Cardiomegaly; Cardiotonic Agents; Carvedilol; Diacylglycerol Kinase; Disease Models, Animal; Kidney; Male; Myocardium; Nephrectomy; Phosphatidylinositol 4,5-Diphosphate; Rats, Wistar; Receptors, Adrenergic, beta-1

Topics: Animals; Arterial Occlusive Diseases; Blood Platelets; Calcium; Calcium Signaling; Disease Models, Animal; Infarction, Middle Cerebral Artery; Lectins, C-Type; Mice, Mutant Strains; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C beta; Phospholipase C gamma; Phosphorylation; Platelet Membrane Glycoproteins; Point Mutation; Receptors, Proteinase-Activated; Stromal Interaction Molecule 1; Synaptophysin; Thrombosis; TRPM Cation Channels

Topics: Actins; Animals; Cells, Cultured; Chloride Channels; Dent Disease; Disease Models, Animal; Endocytosis; Endosomes; Humans; Kidney; Kidney Tubules, Proximal; Locomotion; Low Density Lipoprotein Receptor-Related Protein-2; Lysosomes; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Oculocerebrorenal Syndrome; Phosphatidylinositol 4,5-Diphosphate; Phosphoric Monoester Hydrolases

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Gene Knockdown Techniques; Hippocampus; Humans; Lysosomes; Mice; Mice, Transgenic; Mutation; Peptide Fragments; Phosphatidylinositol 4,5-Diphosphate; Phosphoric Monoester Hydrolases; Presenilin-1

Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Myocytes, Cardiac; Norepinephrine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol-4-Phosphate 3-Kinase; Rats; Rats, Sprague-Dawley

Topics: Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Ganglia, Spinal; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain Measurement; Pain Threshold; Phosphatidylinositol 4,5-Diphosphate; Phosphopyruvate Hydratase; Phosphotransferases (Alcohol Group Acceptor); Reaction Time; Sensory Receptor Cells; Spinal Cord

Topics: Anemia, Hypochromic; Animals; Cell Differentiation; Clathrin-Coated Vesicles; Disease Models, Animal; Endocytosis; Erythroblasts; Erythropoiesis; Hematopoiesis; Hematopoietic Stem Cells; Immunophenotyping; Lymphopoiesis; Mice; Mice, Knockout; Monomeric Clathrin Assembly Proteins; Myelopoiesis; Phenotype; Phosphatidylinositol 4,5-Diphosphate; Polycythemia Vera; Protein Interaction Domains and Motifs; Receptors, Transferrin

Topics: Animals; cdc42 GTP-Binding Protein; Chloride Channels; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Disease Models, Animal; Female; Hypertension; Kidney Diseases; Male; Mice; Microfilament Proteins; p21-Activated Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Podocytes; rac1 GTP-Binding Protein; rho-Associated Kinases; Sialoglycoproteins

Topics: Animals; Arginine; Disease Models, Animal; Epilepsy; KCNQ Potassium Channels; Methylation; Mice, Inbred C57BL; Phosphatidylinositol 4,5-Diphosphate; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases

Topics: Abnormalities, Multiple; Animals; Cell Line; Cerebellum; Cilia; Disease Models, Animal; Embryo, Mammalian; Eye Abnormalities; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Hedgehog Proteins; Humans; Kidney Diseases, Cystic; Kruppel-Like Transcription Factors; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphoric Monoester Hydrolases; Retina; Retinal Pigment Epithelium; Second Messenger Systems; Smoothened Receptor; Time Factors; Transfection; Zinc Finger Protein Gli2

Topics: Animals; Brain; Cognition Disorders; Disease Models, Animal; Down Syndrome; Gene Dosage; Homeostasis; Learning; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Phosphatidylinositol 4,5-Diphosphate; Phosphoric Monoester Hydrolases

Topics: Animals; Brain; Cell Survival; Clathrin; Disease Models, Animal; Embryo, Nonmammalian; Embryonic Development; Endosomes; Gene Expression Profiling; Golgi Apparatus; Hot Temperature; Oculocerebrorenal Syndrome; Phosphatidylinositol 4,5-Diphosphate; Phosphoric Monoester Hydrolases; Protein Splicing; Proto-Oncogene Proteins c-akt; Seizures; Signal Transduction; Zebrafish; Zebrafish Proteins

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Coronary Stenosis; Disease Models, Animal; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Heart Failure; Heart Ventricles; Imidazoles; Imidazolidines; Male; Myocardium; Oleic Acid; Phosphatidate Phosphatase; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Rats; Rats, Sprague-Dawley; Sarcolemma; Time Factors

Topics: Animals; Anorexia; Arcuate Nucleus of Hypothalamus; Disease Models, Animal; Enzyme Activation; Insulin; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Rats; Rats, Wistar

Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Cyclic AMP; Disease Models, Animal; Dogs; Epithelial Cells; Exocytosis; Inositol 1,4,5-Trisphosphate; Ion Channels; Mucins; Pancreatic Ducts; Pancreatitis; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Receptor, PAR-2; Trypsin; Type C Phospholipases

Topics: Animals; Brain Injuries; Disease Models, Animal; Hippocampus; Male; Muscarinic Antagonists; Phosphatidylinositol 4,5-Diphosphate; Rats; Rats, Sprague-Dawley; Scopolamine; Signal Transduction

Topics: Animals; Calcium; Cell Membrane; Cerebellum; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Down Syndrome; Down-Regulation; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Isoenzymes; Male; Mice; Mice, Neurologic Mutants; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C beta; Protein Isoforms; Receptor, Serotonin, 5-HT2A; Receptors, Muscarinic; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Subcellular Fractions; Tritium; Type C Phospholipases

Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Diglycerides; Disease Models, Animal; Fatty Acids; Ischemic Attack, Transient; Male; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Time Factors