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glycerol and Trypanosomiasis, African

glycerol has been researched along with Trypanosomiasis, African in 17 studies

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Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Research Excerpts

ExcerptRelevanceReference
"Suramin was very effective, even after combined therapy had failed repeatedly, while melarsoprol was less effective."1.27Trypanosoma brucei and T. vivax: salicylhydroxamic acid and glycerol treatment of acute and chronically infected rats. ( van der Meer, C; Versluijs-Broers, JA, 1986)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's1 (5.88)18.2507
2000's2 (11.76)29.6817
2010's2 (11.76)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Bringaud, F1
Plazolles, N1
Pineda, E1
Asencio, C1
Villafraz, O1
Millerioux, Y1
Rivière, L1
Tetaud, E1
Jeacock, L1
Baker, N1
Wiedemar, N1
Mäser, P1
Horn, D1
Balogun, EO1
Inaoka, DK1
Shiba, T1
Kido, Y1
Tsuge, C1
Nara, T1
Aoki, T1
Honma, T1
Tanaka, A1
Inoue, M1
Matsuoka, S1
Michels, PA1
Kita, K3
Harada, S1
SEED, JR1
BAQUERO, MA1
DUDA, JF1
Ndao, M1
Magnus, E1
Büscher, P1
Geerts, S1
Yabu, Y2
Suzuki, T1
Nihei, C1
Minagawa, N2
Hosokawa, T1
Nagai, K2
Ohta, N2
Amole, BO1
Clarkson, AB3
Opperdoes, FR1
Evans, DA2
Brightman, CA1
Meguro, K1
Sakajo, S1
Yoshimoto, A1
Brohn, FH2
Brightman, CJ1
Holland, MF1
Van Der Meer, C2
Versluijs-Broers, JA2
Kiaira, JK1
Njogu, RM1
Raseroka, BH1
Ormerod, WE1

Other Studies

17 other studies available for glycerol and Trypanosomiasis, African

ArticleYear
Glycerol, a possible new player in the biology of trypanosomes.
    PLoS pathogens, 2021, Volume: 17, Issue:12

    Topics: Biology; Glycerol; Humans; Trypanosoma brucei brucei; Trypanosomiasis, African

2021
Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity.
    PLoS pathogens, 2017, Volume: 13, Issue:3

    Topics: Animals; Aquaglyceroporins; Biological Transport; Disease Models, Animal; Drug Resistance; Gene Knoc

2017
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
    Molecular microbiology, 2014, Volume: 94, Issue:6

    Topics: Adenosine Diphosphate; Catalytic Domain; Crystallography, X-Ray; Glycerol; Glycerol Kinase; Humans;

2014
INHIBITION OF HEXOSE AND GLYCEROL UTILIZATION BY 2-DEOXY-D-GLUCOSE IN TRYPANOSOMA GAMBIENSE AND TRYPANOSOMA RHODESIENSE.
    Experimental parasitology, 1965, Volume: 16

    Topics: Animals; Antimetabolites; Biological Transport; Carbohydrate Metabolism; Deoxyglucose; Fermentation;

1965
Trypanosoma vivax: a simplified protocol for in vivo growth, isolation and cryopreservation.
    Parasite (Paris, France), 2004, Volume: 11, Issue:1

    Topics: Animals; Cattle; Centrifugation, Density Gradient; Cryopreservation; Cryoprotective Agents; Dimethyl

2004
Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol.
    Parasitology international, 2006, Volume: 55, Issue:1

    Topics: Animals; Disease Models, Animal; Glycerol; Male; Mice; Mice, Inbred BALB C; Sesquiterpenes; Treatmen

2006
Trypanosoma brucei: host parasite interaction in parasite destruction by salicylhydroxamic acid and glycerol in mice.
    Experimental parasitology, 1981, Volume: 51, Issue:1

    Topics: Animals; Blood Physiological Phenomena; Glycerol; Host-Parasite Interactions; Hydroxamic Acids; Kine

1981
Miconazole: an inhibitor of cyanide-insensitive respiration in Trypanosoma brucei.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1980, Volume: 74, Issue:3

    Topics: Animals; Glycerol; Glycerolphosphate Dehydrogenase; Imidazoles; Mice; Miconazole; Trypanosoma brucei

1980
Pleomorphism and the problem of recrudescent parasitaemia following treatment with salicylhydroxamic acid (SHAM) in African trypanosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1980, Volume: 74, Issue:5

    Topics: Animals; Blood; Drug Combinations; Female; Glycerol; Hydroxamic Acids; Mice; Polymorphism, Genetic;

1980
An antibiotic, ascofuranone, specifically inhibits respiration and in vitro growth of long slender bloodstream forms of Trypanosoma brucei brucei.
    Molecular and biochemical parasitology, 1997, Volume: 84, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Electron Transport; Energy Metabolism; Glucose; Glycerol; Glyceropho

1997
Quantitative effects of salycylhydroxamic acid and glycerol on Trypanosoma brucei glycolysis in vitro and in vivo.
    Acta tropica, 1978, Volume: 35, Issue:1

    Topics: Animals; Glycerol; Glycolysis; Hydroxamic Acids; Rats; Trypanosoma brucei brucei; Trypanosomiasis, A

1978
Salicylhydroxamic-acid/glycerol in experimental trypanosomiasis.
    Lancet (London, England), 1977, Oct-08, Volume: 2, Issue:8041

    Topics: Animals; Drug Therapy, Combination; Glycerol; Hydroxamic Acids; Mice; Salicylamides; Trypanocidal Ag

1977
Trypanosoma brucei: trypanocidal effect of salicylhydroxamic acid plus glycerol in infected rats.
    Experimental parasitology, 1979, Volume: 48, Issue:1

    Topics: Animals; Brain; Drug Therapy, Combination; Female; Glycerol; Hydroxamic Acids; Rats; Salicylamides;

1979
Trypanosomiasis: an approach to chemotherapy by the inhibition of carbohydrate catabolism.
    Science (New York, N.Y.), 1976, Oct-08, Volume: 194, Issue:4261

    Topics: Animals; Cattle; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Glycerol; Glycolysis;

1976
Trypanosoma brucei brucei: the catabolism of glycolytic intermediates by digitonin-permeabilized bloodstream trypomastigotes and some aspects of regulation of anaerobic glycolysis.
    The International journal of biochemistry, 1988, Volume: 20, Issue:10

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Cell Membrane Permeability; Di

1988
Trypanosoma brucei and T. vivax: salicylhydroxamic acid and glycerol treatment of acute and chronically infected rats.
    Experimental parasitology, 1986, Volume: 62, Issue:1

    Topics: Animals; Brain; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycerol; Melarsopr

1986
Protection of the sleeping sickness trypanosome from chemotherapy by different parts of the brain.
    East African medical journal, 1985, Volume: 62, Issue:7

    Topics: Animals; Blood-Brain Barrier; Cerebral Cortex; Cerebral Ventricles; Choroid Plexus; Female; Glycerol

1985