Page last updated: 2024-10-18

glycerol and Subarachnoid Hemorrhage

glycerol has been researched along with Subarachnoid Hemorrhage in 30 studies

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Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
"Cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) remains a major complication in patients suffering from SAH."5.31Prevention of cerebral vasospasm by a capsaicin derivative, glyceryl nonivamide, in an experimental model of subarachnoid hemorrhage. ( Chang, CZ; Chen, IJ; Howng, SL; Kwan, AL; Lin, CL; Lo, YC, 2001)
" The authors' goal was to characterize patterns of markers of energy metabolism (glucose, pyruvate, and lactate) and neuronal injury (glutamate and glycerol) in patients with subarachnoid hemorrhage (SAH), in whom ischemia was or was not suspected."5.09Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage. ( Bjerre, P; Schulz, MK; Tange, M; Wang, LP, 2000)
"Bedside intracerebral microdialysis monitoring of patients with subarachnoid hemorrhage and signs of delayed ischemia revealed dramatic changes in extracellular concentrations of glucose, lactate, and glycerol that could be directly correlated to the clinical status of the patients."3.70Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration. ( Brandt, L; Nilsson, OG; Säveland, H; Ungerstedt, U, 1999)
"The effects of hyperoxia, glycerol and ventricular drainage on intracranial pressure (ICP) and cerebral blood flow (CBF) were studied in cases with cerebrospinal fluid (CSF) circulatory-absorbance disturbance due to subarachnoid hemorrhage (SAH) or intraventricular hematoma."3.67[Effects of hyperoxia, glycerol and ventricular drainage on ICP and CBF in patients with increased ICP due to CSF circulatory-absorbance disturbance]. ( Hadeishi, H; Hinuma, Y; Kawamura, S; Nemoto, M; Ohta, H; Suzuki, E, 1987)
"Thirteen subarachnoid hemorrhage patients (age, 48."2.71Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study. ( Amthauer, H; Haux, D; Küchler, I; Lüdemann, L; Plotkin, M; Sarrafzadeh, AS; Unterberg, AW, 2004)
"Aneurysmal subarachnoid hemorrhage (SAH) is frequently associated with delayed neurological deterioration (DND)."1.40Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage. ( Jacobsen, A; Nielsen, TH; Nilsson, O; Nordström, CH; Schalén, W, 2014)
"In the treatment of patients with aneurysmal subarachnoid hemorrhage (SAH), early occlusion of the aneurysm is necessary as well as monitoring and treatment of complications following the primary bleeding episode."1.32Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage. ( Bjerre, P; Kristensen, SR; Schulz, M; Skjøth-Rasmussen, J, 2004)
"Cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) remains a major complication in patients suffering from SAH."1.31Prevention of cerebral vasospasm by a capsaicin derivative, glyceryl nonivamide, in an experimental model of subarachnoid hemorrhage. ( Chang, CZ; Chen, IJ; Howng, SL; Kwan, AL; Lin, CL; Lo, YC, 2001)
"Glycerol was measured in microdialysis samples from the frontal lobe cortex in four patients in the neurointensive care unit, during the acute phase after severe aneurysmal subarachnoid haemorrhage."1.30Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain. ( Enblad, P; Hillered, L; Persson, L; Valtysson, J, 1998)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19906 (20.00)18.7374
1990's3 (10.00)18.2507
2000's11 (36.67)29.6817
2010's7 (23.33)24.3611
2020's3 (10.00)2.80

Authors

AuthorsStudies
Forsse, A1
Nielsen, TH2
Mølstrøm, S1
Hjelmborg, J1
Nielsen, KS1
Nygaard, KH1
Yilmaz, S1
Nordström, CH2
Poulsen, FR1
Adamkov, J1
Poczos, P1
Kanta, M1
Habalova, J1
Bartos, M1
Travnicek, P1
Mejzlik, J1
Cesak, T1
Nagashima, H1
Miwa, T1
Horiguchi, T1
Tomio, R1
Nakagawa, Y1
Yoshida, K1
Forssten, MP1
Thelin, EP1
Nelson, DW1
Bellander, BM1
Kofler, M1
Gaasch, M1
Rass, V1
Schiefecker, AJ1
Ianosi, B1
Lindner, A1
Beer, R1
Stover, JF1
Rhomberg, P1
Pfausler, B1
Thomé, C1
Schmutzhard, E1
Helbok, R1
Jacobsen, A1
Nilsson, O1
Schalén, W1
Nagel, A1
Graetz, D1
Schink, T1
Frieler, K1
Sakowitz, O2
Vajkoczy, P1
Sarrafzadeh, A2
Kinoshita, K1
Moriya, T1
Utagawa, A1
Sakurai, A1
Mukoyama, T1
Furukawa, M1
Yamaguchi, J1
Tanjoh, K1
Zetterling, M1
Hillered, L2
Enblad, P2
Karlsson, T1
Ronne-Engström, E1
Haux, D2
Benndorf, G2
Herzog, H1
Kuechler, I1
Unterberg, A1
Skjøth-Rasmussen, J1
Schulz, M1
Kristensen, SR1
Bjerre, P2
Sarrafzadeh, AS2
Lüdemann, L1
Amthauer, H1
Plotkin, M1
Küchler, I1
Unterberg, AW2
Hillman, J2
Milos, P1
Yu, ZQ1
Sjögren, F1
Anderson, C1
Mellergård, P2
Aneman, O1
Persson, M1
Andersson, C1
Dabrosin, C1
Eide, PK1
Bentsen, G1
Stanisic, M1
Stubhaug, A1
Maeda, M1
Mori, K1
Valtysson, J1
Persson, L1
Nilsson, OG1
Brandt, L1
Ungerstedt, U1
Säveland, H1
Schulz, MK1
Wang, LP1
Tange, M1
Lin, CL1
Lo, YC1
Chang, CZ1
Kwan, AL1
Chen, IJ1
Howng, SL1
Sakowitz, OW1
Kiening, KL1
Lanksch, WR1
Ohta, H1
Suzuki, E1
Hinuma, Y1
Kawamura, S1
Nemoto, M1
Hadeishi, H1
Dodson, RF1
Hashi, K4
Meyer, JS5
Welch, KM3
Mathew, NT1
Hartmann, A1
Shinmaru, S2
Teraura, T2
Kamp, MA1
Dibué, M1
Slotty, P1
Steiger, HJ1
Hänggi, D1
Banfield, JC1
Abdolell, M1
Shankar, JS1
Lahner, D1
Marhold, F1
Gruber, A1
Schramm, W1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779]12 participants (Actual)Observational2017-08-28Completed
Cerebral Autoregulation in Patients With Aneurysmal SubArachnoid Haemorrhage[NCT03987139]45 participants (Anticipated)Interventional2019-06-15Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for glycerol and Subarachnoid Hemorrhage

ArticleYear
Acute focal neurological deficits in aneurysmal subarachnoid hemorrhage: relation of clinical course, CT findings, and metabolite abnormalities monitored with bedside microdialysis.
    Stroke, 2003, Volume: 34, Issue:6

    Topics: Acute Disease; Biomarkers; Brain; Cerebral Angiography; Demography; Disease Progression; Female; Glu

2003
Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study.
    Stroke, 2004, Volume: 35, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Flow Velocity; Brain; Brain Ischemia; Cerebrovascular Circulation; Ex

2004
Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2000, Volume: 93, Issue:5

    Topics: Adult; Aged; Brain; Brain Death; Brain Ischemia; Cerebral Angiography; Extracellular Space; Glucose;

2000

Other Studies

27 other studies available for glycerol and Subarachnoid Hemorrhage

ArticleYear
A Prospective Observational Feasibility Study of Jugular Bulb Microdialysis in Subarachnoid Hemorrhage.
    Neurocritical care, 2020, Volume: 33, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Cerebrovascular Circulation; Feasibility Studies

2020
The effect of free glycerol intake on cerebral glycerol concentration.
    Bratislavske lekarske listy, 2021, Volume: 122, Issue:1

    Topics: Brain; Glycerol; Humans; Microdialysis; Retrospective Studies; Subarachnoid Hemorrhage

2021
Hyperperfusion after Clipping of Aneurysm: A Rare Entity.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:5

    Topics: Aged; Aneurysm, Ruptured; Angiography, Digital Subtraction; Antipyrine; Cerebral Angiography; Cerebr

2018
The Role of Glycerol-Containing Drugs in Cerebral Microdialysis: A Retrospective Study on the Effects of Intravenously Administered Glycerol.
    Neurocritical care, 2019, Volume: 30, Issue:3

    Topics: Administration, Intravenous; Adult; Brain Injuries, Traumatic; Cerebrum; Critical Care; Extracellula

2019
The Importance of Probe Location for the Interpretation of Cerebral Microdialysis Data in Subarachnoid Hemorrhage Patients.
    Neurocritical care, 2020, Volume: 32, Issue:1

    Topics: Aged; Aneurysm, Ruptured; Brain; Brain Edema; Brain Ischemia; Cohort Studies; Female; Glucose; Gluta

2020
Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage.
    Acta neurologica Scandinavica, 2014, Volume: 130, Issue:3

    Topics: Aged; Biomarkers; Brain Ischemia; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Human

2014
Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage. Clinical article.
    Journal of neurosurgery, 2009, Volume: 111, Issue:1

    Topics: Adult; Brain; Brain Diseases; Craniotomy; Decompression, Surgical; Energy Metabolism; Female; Glutam

2009
Change in brain glucose after enteral nutrition in subarachnoid hemorrhage.
    The Journal of surgical research, 2010, Volume: 162, Issue:2

    Topics: Aged; Blood Flow Velocity; Blood Glucose; Blood Pressure; Brain; Enteral Nutrition; Glucose; Glutami

2010
Relation between brain interstitial and systemic glucose concentrations after subarachnoid hemorrhage.
    Journal of neurosurgery, 2011, Volume: 115, Issue:1

    Topics: Aged; Blood Glucose; Brain; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hyp

2011
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Intracerebral microdialysis in neurosurgical intensive care patients utilising catheters with different molecular cut-off (20 and 100 kD).
    Acta neurochirurgica, 2006, Volume: 148, Issue:3

    Topics: Brain Chemistry; Brain Injuries; Catheters, Indwelling; Cerebral Cortex; Coma; Critical Care; Extrac

2006
Variations in the response of interleukins in neurosurgical intensive care patients monitored using intracerebral microdialysis.
    Journal of neurosurgery, 2007, Volume: 106, Issue:5

    Topics: Brain; Brain Concussion; Brain Injuries; Brain Ischemia; Cathepsin D; Critical Care; Enzyme-Linked I

2007
Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:9

    Topics: Aged; Brain; Brain Ischemia; Female; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Intracr

2007
[Hypervolemic hemodilution therapy for clinical vasospasm after aneurysmal subarachnoid hemorrhage].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Adult; Aged; Albumins; Dextrans; Female; Glycerol; Hemodilution; Hemodynamics; Humans; Intracranial

1993
Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain.
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 64, Issue:4

    Topics: Acute Disease; Aged; Biomarkers; Blood-Brain Barrier; Brain Chemistry; Brain Ischemia; Female; Glyce

1998
Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration.
    Neurosurgery, 1999, Volume: 45, Issue:5

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain Ischemia; Cerebral Cortex; Female; Glutamic Acid; Glyc

1999
Prevention of cerebral vasospasm by a capsaicin derivative, glyceryl nonivamide, in an experimental model of subarachnoid hemorrhage.
    Surgical neurology, 2001, Volume: 55, Issue:5

    Topics: Animals; Capsaicin; Disease Models, Animal; Glycerol; Male; Rabbits; Subarachnoid Hemorrhage; Vasosp

2001
Bedside microdialysis: a tool to monitor cerebral metabolism in subarachnoid hemorrhage patients?
    Critical care medicine, 2002, Volume: 30, Issue:5

    Topics: Adult; Aged; Brain; Brain Ischemia; Environmental Monitoring; Female; Glasgow Coma Scale; Glucose; G

2002
[Effects of hyperoxia, glycerol and ventricular drainage on ICP and CBF in patients with increased ICP due to CSF circulatory-absorbance disturbance].
    No to shinkei = Brain and nerve, 1987, Volume: 39, Issue:3

    Topics: Adult; Aged; Cerebral Hemorrhage; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Cerebrovascular C

1987
The effect of glycerol and intracarotid phenoxybenzamine after experimental subarachnoid hemorrhage. An ultrastructural study.
    Acta neuropathologica, 1973, Mar-30, Volume: 24, Issue:1

    Topics: Animals; Autopsy; Brain Edema; Glycerol; Haplorhini; Microscopy, Electron; Papio; Perfusion; Phenoxy

1973
Reconsideration of the role of serotonin in subarachnoid haemorrhage.
    Proceedings of the Australian Association of Neurologists, 1973, Volume: 9

    Topics: Animals; Blood Pressure; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Glyce

1973
Diagnosis and treatment of factors complicating subarachnoid hemorrhage.
    Neuroradiology, 1974, Volume: 6, Issue:5

    Topics: Blood Volume; Brain Edema; Cerebral Angiography; Cerebral Ventriculography; Cerebrovascular Circulat

1974
Hemodynamic and metabolic changes in experimental subarachnoid hemorrhage in monkeys.
    European neurology, 1972, Volume: 8, Issue:1

    Topics: Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Electroencephalography; Gly

1972
Effect of glycerol and intracarotid phenoxybenzamine on cerebral hemodynamics and metabolism after experimental subarachnoid hemorrhage.
    Journal of the neurological sciences, 1972, Volume: 17, Issue:1

    Topics: Animals; Blood Pressure; Brain Edema; Cerebrovascular Circulation; Glycerol; Haplorhini; Ischemic At

1972
Impact of the moon on cerebral aneurysm rupture.
    Acta neurochirurgica, 2013, Volume: 155, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Female; Humans; Incidence; Intracran

2013
Secular pattern of aneurismal rupture with the lunar cycle and season.
    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2017, Volume: 23, Issue:1

    Topics: Aneurysm, Ruptured; Embolization, Therapeutic; Female; Humans; Intracranial Aneurysm; Male; Middle A

2017
Impact of the lunar cycle on the incidence of aneurysmal subarachnoid haemorrhage: myth or reality?
    Clinical neurology and neurosurgery, 2009, Volume: 111, Issue:4

    Topics: Austria; Female; Folklore; Humans; Incidence; Intracranial Aneurysm; Male; Middle Aged; Moon; Retros

2009