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glycerol and Renal Insufficiency

glycerol has been researched along with Renal Insufficiency in 8 studies

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Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.

Research Excerpts

ExcerptRelevanceReference
"0 microg kg(-1) min(-1)) or saline on renal blood flow and function in 10 anaesthetized Labrador dogs in whom rhabdomyolysis and myoglobinuric acute renal failure had been induced by administration of glycerol 50% (10mL kg(-1)) intramuscularly."7.72Effects of fenoldopam on renal blood flow and its function in a canine model of rhabdomyolysis. ( Corcoran, T; Markos, F; Murray, C; Parfrey, N; Shorten, GD; Snow, HM, 2003)
" Glycerol injection into rats induces severe acute renal failure (ARF) with ischemia and tubular necrosis, a model which shares many features with human ARF or rhabdomyolysis."7.71Ameliorative effect of hepatocyte growth factor on glycerol-induced acute renal failure with acute tubular necrosis. ( Kawamura, T; Mori-Kudo, I; Nagano, T; Noguchi, H; Taiji, M; Tsuchida, A, 2002)
" Panipenem and betamipron were administered intravenously to rats with a variety of renal failures, such as nephritis induced by glycerol, gentamicin, uranium and antiserum against glomerular basement membrane as well as 5/6 subtotal nephrectomy."3.73Quantitative evaluation of effect of renal failure on the pharmacokinetics of panipenem in rats. ( Ishizuka, H; Naganuma, H; Soma, M; Tajima, N, 2005)
"0 microg kg(-1) min(-1)) or saline on renal blood flow and function in 10 anaesthetized Labrador dogs in whom rhabdomyolysis and myoglobinuric acute renal failure had been induced by administration of glycerol 50% (10mL kg(-1)) intramuscularly."3.72Effects of fenoldopam on renal blood flow and its function in a canine model of rhabdomyolysis. ( Corcoran, T; Markos, F; Murray, C; Parfrey, N; Shorten, GD; Snow, HM, 2003)
" Glycerol injection into rats induces severe acute renal failure (ARF) with ischemia and tubular necrosis, a model which shares many features with human ARF or rhabdomyolysis."3.71Ameliorative effect of hepatocyte growth factor on glycerol-induced acute renal failure with acute tubular necrosis. ( Kawamura, T; Mori-Kudo, I; Nagano, T; Noguchi, H; Taiji, M; Tsuchida, A, 2002)
" This study was designed to clarify changes in HGF pharmacokinetics in renal failure and to establish a pharmacokinetic model applicable to single and repeated doses."1.39Pharmacokinetic modeling of hepatocyte growth factor in experimental animals and humans. ( Abe, T; Adachi, K; Fukuta, K; Kato, Y; Matsumoto, K; Nakamichi, N; Nakamura, T; Sano, K; Sugiura, T; Takahashi, S, 2013)
"Renal failure was induced by five-sixths nephrectomy (NR), bilateral ureter ligation (BUL), the intramuscular injection of glycerol (GL), and the intraperitoneal injection of cisplatin (CDDP)."1.32The hepatic and intestinal metabolic activities of P450 in rats with surgery- and drug-induced renal dysfunction. ( Hashimoto, Y; Hasunuma, M; Okabe, H, 2003)
"Administration of alkali, a treatment for rhabdomyolysis, improved renal function and significantly reduced the urinary excretion of F2-isoprostanes by approximately 80%."1.30A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure. ( Anand, R; Clozel, M; Cooper, CE; Darley-Usmar, V; Goodier, D; Holt, SG; Moore, KP; Morrow, JD; Patel, RP; Reeder, BJ; Roberts, LJ; Svistunenko, DA; Wilson, MT; Zackert, W, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adedapo, AA1
Oyekan, AO1
Sugiura, T1
Takahashi, S1
Sano, K1
Abe, T1
Fukuta, K1
Adachi, K1
Nakamura, T1
Matsumoto, K1
Nakamichi, N1
Kato, Y1
Nagano, T1
Mori-Kudo, I1
Tsuchida, A1
Kawamura, T1
Taiji, M1
Noguchi, H1
Murray, C1
Markos, F1
Snow, HM1
Corcoran, T1
Parfrey, N1
Shorten, GD1
VALERI, CR1
HENDERSON, ME1
Okabe, H1
Hasunuma, M1
Hashimoto, Y1
Tajima, N1
Soma, M1
Ishizuka, H1
Naganuma, H1
Moore, KP1
Holt, SG1
Patel, RP1
Svistunenko, DA1
Zackert, W1
Goodier, D1
Reeder, BJ1
Clozel, M1
Anand, R1
Cooper, CE1
Morrow, JD1
Wilson, MT1
Darley-Usmar, V1
Roberts, LJ1

Other Studies

8 other studies available for glycerol and Renal Insufficiency

ArticleYear
Effects of fenofibrate, a PPAR-α ligand, on the haemodynamics of glycerol-induced renal failure in rats.
    Human & experimental toxicology, 2013, Volume: 32, Issue:3

    Topics: Animals; Arterial Pressure; Fenofibrate; Glycerol; Hemodynamics; Kidney; Ligands; Male; PPAR alpha;

2013
Pharmacokinetic modeling of hepatocyte growth factor in experimental animals and humans.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:1

    Topics: Acute Disease; Animals; Area Under Curve; Disease Models, Animal; Drug Administration Schedule; Endo

2013
Ameliorative effect of hepatocyte growth factor on glycerol-induced acute renal failure with acute tubular necrosis.
    Nephron, 2002, Volume: 91, Issue:4

    Topics: Acute Disease; Animals; Glycerol; Hepatocyte Growth Factor; Kidney Tubules; Male; Necrosis; Rats; Ra

2002
Effects of fenoldopam on renal blood flow and its function in a canine model of rhabdomyolysis.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:9

    Topics: Animals; Antihypertensive Agents; Creatinine; Disease Models, Animal; Dogs; Female; Fenoldopam; Glyc

2003
RECENT DIFFICULTIES WITH FROZEN GLYCEROLIZED BLOOD.
    JAMA, 1964, Jun-29, Volume: 188

    Topics: Acute Kidney Injury; Blood Transfusion; Cold Temperature; Erythrocytes; Freezing; Glycerol; Hemoglob

1964
The hepatic and intestinal metabolic activities of P450 in rats with surgery- and drug-induced renal dysfunction.
    Pharmaceutical research, 2003, Volume: 20, Issue:10

    Topics: Animals; Cisplatin; Cytochrome P-450 Enzyme System; Debrisoquin; Glycerol; Hydroxylation; Hydroxytes

2003
Quantitative evaluation of effect of renal failure on the pharmacokinetics of panipenem in rats.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:11

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Autoantibodies; Basement Membrane; Blood Urea Nitr

2005
A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure.
    The Journal of biological chemistry, 1998, Nov-27, Volume: 273, Issue:48

    Topics: Animals; Bicarbonates; Dinoprost; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Glyc

1998