glycerol has been researched along with Myoglobinuria in 41 studies
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Myoglobinuria: The presence of MYOGLOBIN in URINE usually as a result of rhabdomyolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glycerol treatment resulted in a marked decrease in tissue and urine nitric oxide levels, renal oxidative stress and significantly deranged the renal functions along with deterioration of renal morphology." | 5.33 | Molsidomine, a nitric oxide donor and L-arginine protects against rhabdomyolysis-induced myoglobinuric acute renal failure. ( Chander, V; Chopra, K, 2005) |
| "We found that the levels of creatinine, urea, nitric oxide, alanine transaminase, aspartate aminotransferase, creatine kinase in serum samples, malondialdehyde, nitric oxide, inducible nitric oxide synthase, and endothelial nitric oxide synthase concentrations in renal tissue were increased in the myoglobinuric acute kidney injury group compared with the control group (p<0." | 3.88 | The Effects of Baicalin on Myoglobinuric Acute Renal Failure in Rats. ( Aydoğdu, N; Süt, N; Taştekin, E; Yalçınkaya Yavuz, Ö, 2018) |
| " In glycerol-induced myoglobinuric acute kidney injury, we found an increase in the nuclear factor erythroid 2-related factor 2 (Nrf2) nuclear protein, a key redox-sensitive transcription factor, and Nrf2-regulated genes and proteins including upregulation of heme oxygenase-1." | 3.80 | Inhibition of cytochrome P450 2E1 and activation of transcription factor Nrf2 are renoprotective in myoglobinuric acute kidney injury. ( Baliga, R; Liu, H; Shah, SV; Wang, Z, 2014) |
| "Serum and urine fibrin(ogen) degradation products (FDP), FDP clearances, and serum urea nitrogen (SUN) concentrations of rats challenged with glycerol-induced myohemoglobinuria were measured serially over a period of 4 days." | 3.66 | The pathogenetic significance of intravascular coagulation in experimental acute renal failure. ( Carvalho, AC; Carvalho, JS; Colman, RW; Landwehr, DM; Oken, DE; Page, LB; Vaillancourt, RA, 1978) |
| " Neither mode of immunization significantly affected the degree of azotemia or the marked reduction of inulin clearance expected in rats subjected to glycerol-induced myohemoglobinuria." | 3.65 | Active and passive immunization to angiotensin in experimental acute renal failure. ( Cotes, SC; Flamenbaum, W; Lever, AF; Oken, DE; Powell-Jackson, JD, 1975) |
| "Glycerol (8 ml/kg) was injected into the hind legs of each of the rats in ARF and ARF+HBO groups." | 1.38 | Preventive effects of hyperbaric oxygen treatment on glycerol-induced myoglobinuric acute renal failure in rats. ( Aksu, B; Ayvaz, S; Basaran, UN; Colak, A; Erboga, M; Kanter, M; Pul, M; Uzun, H, 2012) |
| "The occurrence of acute renal failure (ARF) following rhabdomyolysis has been put at between 10 and 40% of cases, and accounts for between 3 and 15% of all cases of ARF." | 1.33 | Reversal of experimental myoglobinuric acute renal failure in rats by quercetin, a bioflavonoid. ( Chander, V; Chopra, K; Singh, D, 2005) |
| "Glycerol treatment resulted in a marked decrease in tissue and urine nitric oxide levels, renal oxidative stress and significantly deranged the renal functions along with deterioration of renal morphology." | 1.33 | Molsidomine, a nitric oxide donor and L-arginine protects against rhabdomyolysis-induced myoglobinuric acute renal failure. ( Chander, V; Chopra, K, 2005) |
| "Glycerol treated rats exhibited collecting duct and medullary ascending limb dilation and casts, with focal tubular damage, confined mainly to the superficial cortex." | 1.31 | Nephroprotective effects of pentoxifylline in experimental myoglobinuric acute renal failure. ( Avramovic, V; Djordjevic, V; Mitic-Zlatkovic, M; Savic, V; Stefanovic, V; Vlahovic, P, 2002) |
| "Glycerol-injected rats treated with BSO showed significantly worse renal failure than did rats given glycerol alone, while administration of GSH resulted in significant amelioration of glycerol-induced acute renal failure [glycerol treatment alone, blood urea nitrogen (BUN) = 96 +/- 10 and creatinine = 2." | 1.28 | Role of glutathione in an animal model of myoglobinuric acute renal failure. ( Abul-Ezz, SR; Shah, SV; Walker, PD, 1991) |
| "Prior acute renal failure (ARF) induced by either glycerol (G) or mercury provides protection against rechallenge with the same agent or the other." | 1.27 | Protection against acute renal failure by prior acute renal failure: differences between myohemoglobinuric and ischemic models. ( Hollenberg, NK; Wilkes, BM, 1987) |
| "Thus, in contrast to human acute renal failure, marked renal cortical ischemia is not an essential feature of these different forms of murine acute renal failure." | 1.26 | Normal renocortical blood flow in experimental acute renal failure. ( Carvalho, JS; Churchill, S; Gottlieb, MN; Oken, DE; Zarlengo, MD, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (41.46) | 18.7374 |
| 1990's | 9 (21.95) | 18.2507 |
| 2000's | 12 (29.27) | 29.6817 |
| 2010's | 3 (7.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yalçınkaya Yavuz, Ö | 1 |
| Aydoğdu, N | 2 |
| Taştekin, E | 1 |
| Süt, N | 1 |
| Wang, Z | 1 |
| Shah, SV | 4 |
| Liu, H | 1 |
| Baliga, R | 2 |
| Ustundag, S | 2 |
| Yalcin, O | 3 |
| Sen, S | 2 |
| Cukur, Z | 1 |
| Ciftci, S | 2 |
| Demirkan, B | 2 |
| Ture, M | 1 |
| Ayvaz, S | 1 |
| Aksu, B | 1 |
| Kanter, M | 1 |
| Uzun, H | 1 |
| Erboga, M | 1 |
| Colak, A | 1 |
| Basaran, UN | 1 |
| Pul, M | 1 |
| Fernández-Fúnez, A | 1 |
| Polo, FJ | 1 |
| Broseta, L | 1 |
| Valer, J | 1 |
| Zafrilla, L | 1 |
| Ferraz, FF | 1 |
| Kos, AG | 1 |
| Janino, P | 1 |
| Homsi, E | 1 |
| Savic, V | 3 |
| Vlahovic, P | 4 |
| Djordjevic, V | 1 |
| Mitic-Zlatkovic, M | 2 |
| Avramovic, V | 2 |
| Stefanovic, V | 4 |
| Chander, V | 2 |
| Singh, D | 1 |
| Chopra, K | 2 |
| Atmaca, G | 1 |
| Batcioglu, K | 1 |
| Kaymak, K | 1 |
| Cvetković, T | 2 |
| Wilkes, BM | 2 |
| Caldicott, WJ | 1 |
| Schulman, G | 1 |
| Hollenberg, NK | 3 |
| Oken, DE | 8 |
| Sprinkel, FM | 1 |
| Kirschbaum, BB | 1 |
| Landwehr, DM | 2 |
| Zager, RA | 4 |
| Burkhart, KM | 1 |
| Conrad, DS | 1 |
| Gmur, DJ | 1 |
| Vexler, VS | 1 |
| Roberts, TP | 1 |
| Rosenau, W | 1 |
| Zhang, Z | 1 |
| Baliga, M | 1 |
| Ishizuka, S | 1 |
| Nagashima, Y | 1 |
| Numata, M | 1 |
| Yano, T | 1 |
| Hagiwara, K | 1 |
| Ozasa, H | 1 |
| Sone, M | 1 |
| Nihei, H | 1 |
| Horikawa, S | 1 |
| Kalhorn, T | 1 |
| Mihailovic, D | 1 |
| Najman, S | 1 |
| Kalhorn, TF | 1 |
| Kertai, E | 1 |
| Hollósi, G | 1 |
| Kovács, J | 1 |
| Varga, V | 1 |
| Carvalho, JS | 2 |
| Carvalho, AC | 1 |
| Vaillancourt, RA | 1 |
| Page, LB | 1 |
| Colman, RW | 1 |
| Bidani, AK | 1 |
| Fleischmann, LE | 1 |
| Churchill, P | 1 |
| Becker-McKenna, B | 1 |
| Sherwood, T | 1 |
| Evans, DJ | 1 |
| Ishikawa, I | 1 |
| Churchill, S | 1 |
| Zarlengo, MD | 1 |
| Gottlieb, MN | 1 |
| Hsu, CH | 1 |
| Kurtz, TW | 1 |
| Goldstein, JR | 1 |
| Keinath, RD | 1 |
| Weller, JM | 1 |
| Cotes, SC | 1 |
| Flamenbaum, W | 3 |
| Powell-Jackson, JD | 1 |
| Lever, AF | 1 |
| Mende, CW | 1 |
| Taraba, I | 1 |
| Walker, PD | 2 |
| Foerder, C | 1 |
| Bredl, C | 1 |
| Abul-Ezz, SR | 1 |
| Mandal, AK | 1 |
| Davis, JB | 1 |
| Bell, RD | 1 |
| Miller, JM | 1 |
| Letteri, JM | 1 |
| Kotchen, TA | 1 |
| Chedru, MF | 1 |
| Baethke, R | 1 |
| David, H | 1 |
| Uerlings, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine in Patient With Diabetic Foot Ulcer Wagner 3-4[NCT03615755] | 30 participants (Actual) | Interventional | 2016-12-27 | Completed | |||
| A Randomized Factorial Trial of N-Acetylcysteine and Continuous Veno-Venous Hemo(Dia)Filtration for Rhabdomyolysis[NCT00391911] | Phase 2 | 3 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for glycerol and Myoglobinuria
| Article | Year |
|---|---|
Post traumatic acute renal failure.
Topics: Acute Kidney Injury; Crush Syndrome; Disease Models, Animal; Glycerol; Humans; Kidney Tubular Necros | 1987 |
40 other studies available for glycerol and Myoglobinuria
| Article | Year |
|---|---|
The Effects of Baicalin on Myoglobinuric Acute Renal Failure in Rats.
Topics: Acute Kidney Injury; Animals; Catalase; Creatine Kinase; Flavonoids; Glutathione; Glutathione Peroxi | 2018 |
Inhibition of cytochrome P450 2E1 and activation of transcription factor Nrf2 are renoprotective in myoglobinuric acute kidney injury.
Topics: Acute Kidney Injury; Animals; Chlormethiazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhi | 2014 |
Experimental myoglobinuric acute renal failure: the effect of vitamin C.
Topics: Acute Kidney Injury; Animals; Ascorbic Acid; Biopsy, Needle; Disease Models, Animal; Glycerol; Immun | 2008 |
L-Carnitine ameliorates glycerol-induced myoglobinuric acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Carnitine; Glycerol; Kidney; Male; Malondialdehyde; Myoglobinuria; Oxi | 2009 |
Preventive effects of hyperbaric oxygen treatment on glycerol-induced myoglobinuric acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Catalase; Creatinine; Glutathione; Glycerol; Hyperbaric Oxygenation; K | 2012 |
Effects of N-acetylcysteine on myoglobinuric-acute renal failure in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Cryoprotective Agents; Disease Models, Animal; Free Ra | 2002 |
Effects of melatonin administration to rats with glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Antioxidants; Cryoprotective Agents; Disease Models, Animal; Drug Admi | 2002 |
Nephroprotective effects of pentoxifylline in experimental myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Glomerular Mesangium; Glycerol; Kidney; Kidney Diseases; Kidney Glomer | 2002 |
Reversal of experimental myoglobinuric acute renal failure in rats by quercetin, a bioflavonoid.
Topics: Acute Kidney Injury; Animals; Antioxidants; Catalase; Drinking; Glutathione; Glycerol; Kidney; Kidne | 2005 |
Effects of caffeic acid phenethyl ester on glycerol-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Caffeic Acids; Glycerol; Injections, Intramuscular; Kidn | 2004 |
Molsidomine, a nitric oxide donor and L-arginine protects against rhabdomyolysis-induced myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Arginine; Glycerol; Kidney; Male; Molsidomine; Myoglobinuria; Nitric O | 2005 |
Dietary curcumin does not protect kidney in glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Antineoplastic Agents; Blood Urea Nitrogen; CD13 | 2007 |
Loss of the glomerular contractile response to angiotensin in rats following myohemoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Bucladesine; Dose-Response Relationshi | 1981 |
Amino acid therapy in the treatment of experimental acute renal failure in the rat.
Topics: Acute Kidney Injury; Amino Acids; Amino Acids, Essential; Animals; Blood Urea Nitrogen; Creatinine; | 1980 |
Iron, heme oxygenase, and glutathione: effects on myohemoglobinuric proximal tubular injury.
Topics: Animals; Cell-Free System; Deferoxamine; Free Radical Scavengers; Glutathione; Glycerol; Heme Oxygen | 1995 |
Early detection of acute tubular injury with diffusion-weighted magnetic resonance imaging in a rat model of myohemoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Urea Nitrogen; Contrast Media; Creatinine; | 1996 |
Evidence for cytochrome P-450 as a source of catalytic iron in myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Ulcer Agents; Bleomycin; Blood Urea Nitrogen; Cimetidine; Creatin | 1996 |
Regulation and immunohistochemical analysis of stress protein heme oxygenase-1 in rat kidney with myoglobinuric acute renal failure.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Enzyme Induction; Glutathione; Glycerol; Heme Oxygenas | 1997 |
Renal cortical ceramide patterns during ischemic and toxic injury: assessments by HPLC-mass spectrometry.
Topics: Animals; Ceramides; Chromatography, High Pressure Liquid; Glycerol; Ischemia; Kidney Cortex; Male; M | 1999 |
Protective effect of a bioflavonoid proanthocyanidin-BP1 in glycerol-induced acute renal failure in the rat: renal stereological study.
Topics: Acute Kidney Injury; Animals; Anthocyanins; Antioxidants; Flavonoids; Glycerol; Kidney; Male; Myoglo | 1999 |
Reversal of experimental myoglobinuric acute renal failure with bioflavonoids from seeds of grape.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Anthocyanins; Antioxidants; Disease Models, Anim | 2000 |
Changes in free and esterified cholesterol: hallmarks of acute renal tubular injury and acquired cytoresistance.
Topics: Acute Kidney Injury; Animals; Cell Hypoxia; Cell Survival; Cholesterol; Cholesterol Esters; Choleste | 2000 |
Effect of glycerol-induced acute renal failure and di-2-ethylhexyl phthalate on the enzymes involved in biotransformation of xenobiotixs.
Topics: Acute Kidney Injury; Animals; Biotransformation; Creatinine; Cytochrome P-450 Enzyme System; Cytochr | 2000 |
The pathogenetic significance of intravascular coagulation in experimental acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Transfusion; Blood Urea Nitrogen; Disease Models, Animal; Dissem | 1978 |
Natriuresis-induced protection in acute myohemoglobinuric renal failure without renal cortical renin content depletion in the rat.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chlorides; Disease Models, Animal; Female; Glycer | 1978 |
Intravenous urography in experimental acute renal failure. Nephrograms and pyelograms in saline-loaded rats.
Topics: Acute Kidney Injury; Animals; Creatinine; Glycerol; Hemoglobinuria; Kidney; Kidney Tubular Necrosis, | 1978 |
Pharmacologic interruption of the renin-angiotensin system in myohemoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Blood Urea Nitrog | 1976 |
Normal renocortical blood flow in experimental acute renal failure.
Topics: Acute Kidney Injury; Animals; Chlorides; Disease Models, Animal; Female; Glomerular Filtration Rate; | 1977 |
Intrarenal hemodynamics in acute myohemoglobinuric renal failure.
Topics: Acute Kidney Injury; Animals; Body Weight; Creatinine; Drinking; Glomerular Filtration Rate; Glycero | 1976 |
Local mechanisms in the pathogenesis of acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Cell Membrane Permeability; Dose-Response Relationship | 1976 |
Active and passive immunization to angiotensin in experimental acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Female; Glomerular Filtration Rate; Gl | 1975 |
Resistance to acute renal failure afforded by prior renal failure: examination of the role of renal renin content.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Female; Glomerular Filtration Rate; Glycerol; Hem | 1975 |
Reactive oxygen metabolites in toxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Calcium; Cell Line; Free Radicals; Gentamicins; Glycerol; Humans; Hydr | 1992 |
The influence of mannitol on myoglobinuric acute renal failure: functional, biochemical, and morphological assessments.
Topics: Acute Kidney Injury; Adenine Nucleotides; Animals; Energy Metabolism; Female; Glycerol; Heme; Lipid | 1991 |
Role of glutathione in an animal model of myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Glutathione; Glycerol; Kidney; Male; | 1991 |
Myoglobinuria exacerbates ischemic renal damage in the dog.
Topics: Acute Kidney Injury; Animals; Creatinine; Dogs; Glycerol; Hematocrit; Injections, Intramuscular; Isc | 1989 |
Protection against acute renal failure by prior acute renal failure: differences between myohemoglobinuric and ischemic models.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Glycerol; Iod | 1987 |
Effect of renin immunization on mercuric chloride and glycerol-induced renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Antigens; Blood Pressure; Blood Urea Nitrogen; Chlorid | 1972 |
Renal cortical blood flow and glomerular filtration in myohemoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Blood Urea Nitrogen; Carbon Radioisotopes; Female | 1972 |
[Electron microscopic studies on the problem of the myolytic effect of glycerin].
Topics: Animals; Edema; Glycerol; Injections, Intramuscular; Microscopy, Electron; Myofibrils; Myoglobinuria | 1965 |