Page last updated: 2024-10-18

glycerol and Muscular Dystrophy, Duchenne

glycerol has been researched along with Muscular Dystrophy, Duchenne in 3 studies

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Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)

Research Excerpts

ExcerptRelevanceReference
"To investigate disease progression and aging, we utilized young (1 month old) and old (21-25 months old) mdx and wild-type tongue muscles."1.91Biomarkers for Duchenne muscular dystrophy progression: impact of age in the mdx tongue spared muscle. ( Chamberlain, JS; Ferretti, R; Lorena, MDSV; Matsumura, CY; Nagana Gowda, GA; Odom, GL; Santos, EKD, 2023)
"All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia."1.32Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Lorena, MDSV1
Santos, EKD1
Ferretti, R1
Nagana Gowda, GA1
Odom, GL1
Chamberlain, JS1
Matsumura, CY1
Hellerud, C1
Adamowicz, M1
Jurkiewicz, D1
Taybert, J1
Kubalska, J1
Ciara, E1
Popowska, E1
Ellis, JR1
Lindstedt, S1
Pronicka, E1
Ørngreen, MC1
Zacho, M1
Hebert, A1
Laub, M1
Vissing, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658]Phase 448 participants (Anticipated)Interventional2019-02-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for glycerol and Muscular Dystrophy, Duchenne

ArticleYear
Biomarkers for Duchenne muscular dystrophy progression: impact of age in the mdx tongue spared muscle.
    Skeletal muscle, 2023, 09-13, Volume: 13, Issue:1

    Topics: Acetic Acid; Alanine; Animals; Creatine; Disease Progression; Glycerol; Isoleucine; Methionine; Mice

2023
Clinical heterogeneity and molecular findings in five Polish patients with glycerol kinase deficiency: investigation of two splice site mutations with computerized splice junction analysis and Xp21 gene-specific mRNA analysis.
    Molecular genetics and metabolism, 2003, Volume: 79, Issue:3

    Topics: Adrenal Insufficiency; Chromosomes, Human, X; DAX-1 Orphan Nuclear Receptor; DNA Mutational Analysis

2003
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H

2003