glycerol has been researched along with Jaundice, Neonatal in 2 studies
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.
Jaundice, Neonatal: Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weisman, LE | 1 |
| Merenstein, GB | 1 |
| Digirol, M | 1 |
| Collins, J | 1 |
| Frank, G | 1 |
| Hudgins, C | 1 |
| Chen, JY | 1 |
| Ling, UP | 1 |
| Chen, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Glycerin Suppositories to Reduce Hyperbilirubinemia in Premature Infants Requiring Phototherapy[NCT01746511] | 79 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
time start to time finally off phototherapy, including any breaks during which they were off (NCT01746511)
Timeframe: from time of enrollment to time of discharge, for a maximum of 10 weeks
| Intervention | hours (Mean) |
|---|---|
| Glycerin Suppository | 118 |
| No Glycerin Suppository | 81 |
"Bilirubin levels are checked at regular intervals after phototherapy is discontinued to make sure levels are safe. Depending on rate of rise and predetermined unsafe bilirubin level, phototherapy may be restarted." (NCT01746511)
Timeframe: from time of enrollment to time of discharge, for a maximum of 10 weeks
| Intervention | episodes of repeat phototherapy (Median) |
|---|---|
| Glycerin Suppository | 0 |
| No Glycerin Suppository | 0 |
Bilirubin levels were checked every 12 hours while the infant was under phototherapy. A bilirubin level was then to be checked at least twice, 8-12 hours or longer apart, following discontinuation of phototherapy. (NCT01746511)
Timeframe: from time of enrollment to time of discharge every 12 hours while under phototherapy, for a maximum of 10 weeks
| Intervention | mg/dL (Mean) |
|---|---|
| Glycerin Suppository | 11.3 |
| No Glycerin Suppository | 12.0 |
Absolute change over time from peak to first discontinuation of phototherapy lights (NCT01746511)
Timeframe: from time of enrollment to time of discharge, for a maximum of 10 weeks
| Intervention | mg/dL/hr (Mean) |
|---|---|
| Glycerin Suppository | 0.4 |
| No Glycerin Suppository | 0.4 |
(NCT01746511)
Timeframe: from time of enrollment to time of discharge, for a maximum of 10 weeks
| Intervention | hours (Mean) |
|---|---|
| Glycerin Suppository | 72 |
| No Glycerin Suppository | 61 |
2 trials available for glycerol and Jaundice, Neonatal
| Article | Year |
|---|---|
The effect of early meconium evacuation on early-onset hyperbilirubinemia.
Topics: Bilirubin; Glycerol; Humans; Infant, Newborn; Jaundice, Neonatal; Meconium; Random Allocation; Suppo | 1983 |
Early meconium evacuation: effect on neonatal hyperbilirubinemia.
Topics: Bilirubin; Enema; Glycerol; Humans; Infant, Newborn; Jaundice, Neonatal; Meconium | 1995 |