Page last updated: 2024-10-18

glycerol and Hemoglobinuria

glycerol has been researched along with Hemoglobinuria in 38 studies

Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.

Hemoglobinuria: The presence of free HEMOGLOBIN in the URINE, indicating hemolysis of ERYTHROCYTES within the vascular system. After saturating the hemoglobin-binding proteins (HAPTOGLOBINS), free hemoglobin begins to appear in the urine.

Research Excerpts

ExcerptRelevanceReference
"Hitherto, treatment of acute cerebral hemorrhage with intravenous glycerol has not been evaluated in rigorous clinical studies with sufficient patient numbers."9.07Treatment of acute cerebral hemorrhage with intravenous glycerol. A double-blind, placebo-controlled, randomized trial. ( Chan, FL; Chang, CM; Cheung, RT; Cheung, YK; Fong, KY; Kou, M; Kumana, CR; Lauder, IJ; Yu, YL, 1992)
"Hitherto, treatment of acute cerebral hemorrhage with intravenous glycerol has not been evaluated in rigorous clinical studies with sufficient patient numbers."5.07Treatment of acute cerebral hemorrhage with intravenous glycerol. A double-blind, placebo-controlled, randomized trial. ( Chan, FL; Chang, CM; Cheung, RT; Cheung, YK; Fong, KY; Kou, M; Kumana, CR; Lauder, IJ; Yu, YL, 1992)
" Subsequent investigation revealed the probable cause of the hemolysis to be inadequate deglycerolization of the unit."3.68Hemolytic transfusion reaction following transfusion of frozen and washed autologous red cells. ( Cregan, P; Donegan, E; Gotelli, G, 1991)
"The beneficial effects of post-insult administration of pentoxifylline, a novel hemorheologic agent experimentally studied in various ischemic diseases, were evaluated in two models of acute renal failure (ARF): direct nephrotoxicity (mercuric chloride 4 mg/kg via femoral vein) and hemoglobinuria (glycerol 10 ml/kg i."3.67Effects of pentoxifylline in experimental acute renal failure. ( Brunner, LJ; Luke, DR; Vadiei, K, 1989)
"Serum and urine fibrin(ogen) degradation products (FDP), FDP clearances, and serum urea nitrogen (SUN) concentrations of rats challenged with glycerol-induced myohemoglobinuria were measured serially over a period of 4 days."3.66The pathogenetic significance of intravascular coagulation in experimental acute renal failure. ( Carvalho, AC; Carvalho, JS; Colman, RW; Landwehr, DM; Oken, DE; Page, LB; Vaillancourt, RA, 1978)
" Neither mode of immunization significantly affected the degree of azotemia or the marked reduction of inulin clearance expected in rats subjected to glycerol-induced myohemoglobinuria."3.65Active and passive immunization to angiotensin in experimental acute renal failure. ( Cotes, SC; Flamenbaum, W; Lever, AF; Oken, DE; Powell-Jackson, JD, 1975)
"The appearance of an acute renal insufficiency in the rabbit, after glycerol injection (10, 13 or 15 ml/kg of a 50% solution) is investigated."1.25Acute renal insufficiency in the rabbit by glycerol. ( Cisar, F; de Vega, F; del Valle, O; Gras, J; Navarro, J; Tuset, N, 1975)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199033 (86.84)18.7374
1990's3 (7.89)18.2507
2000's2 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
POTTER, BJ1
VALERI, CR2
HENDERSON, ME1
DALLNER, G1
ERICSSON, JL3
CAMPANACCI, L2
NACCARATO, R1
SIRIGU, F1
ROMAGNOLI, GF1
Zager, RA1
Johnson, AC1
Lund, S1
Randolph-Habecker, J1
Murakami, S1
Yasuda, T1
Kushikata, T1
Hashimoto, H1
Hirota, K1
Thiel, G3
Wilson, DR4
Arce, ML4
Oken, DE7
Bidani, AK2
Churchill, PC1
Trifillis, AL1
Kahng, MW1
Trump, BF1
Vogt, BA1
Shanley, TP1
Croatt, A1
Alam, J1
Johnson, KJ1
Nath, KA1
Tachibana, H1
Seki, T1
Nara, M1
Carvalho, JS1
Carvalho, AC1
Vaillancourt, RA1
Page, LB1
Colman, RW1
Landwehr, DM1
Fleischmann, LE1
Churchill, P1
Becker-McKenna, B1
Sherwood, T1
Evans, DJ1
Cotes, SC1
Flamenbaum, W2
Powell-Jackson, JD1
Lever, AF1
Mende, CW1
Taraba, I1
Gras, J1
Tuset, N1
de Vega, F1
Cisar, F1
Navarro, J1
del Valle, O1
Yu, YL1
Kumana, CR1
Lauder, IJ1
Cheung, YK1
Chan, FL1
Kou, M1
Chang, CM1
Cheung, RT1
Fong, KY1
Cregan, P1
Donegan, E1
Gotelli, G1
Vadiei, K1
Brunner, LJ1
Luke, DR1
Plass, R1
Schaefer, RM1
Heidland, A1
Hörl, WH1
Hägnevik, K1
Gordon, E1
Lins, LE1
Wilhelmsson, S1
Forster, D1
Wardle, EN1
Wright, NA1
Bondi, R5
Gori, F4
Tosi, P4
Marchi, F2
Moss, GS1
Brodine, CE1
Mostofi, FK2
Lundgren, G1
Santini, F1
Marconi, P1
Hayes, JM1
Boonshaft, B1
Maher, JF1
O'Connell, JM1
Schreiner, GE1
Susini, A1
Bisori, M1
Cirri, GP1
Klosterhalfen, H1
Griebel, O1
Tietzen, M1
Fernandes, NS1
Carlini, EA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Detecting Autologous Transfusion by Measuring Alterations in the Dynamics of Red Blood Cell Maturation and Recycling[NCT02684747]Early Phase 140 participants (Actual)Interventional2016-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for glycerol and Hemoglobinuria

ArticleYear
Treatment of acute cerebral hemorrhage with intravenous glycerol. A double-blind, placebo-controlled, randomized trial.
    Stroke, 1992, Volume: 23, Issue:7

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cerebral Hemorrhage; Double-Blind Method; Glycerol; H

1992
Clinical experience with the use of frozen blood in combat casualties.
    The New England journal of medicine, 1968, Apr-04, Volume: 278, Issue:14

    Topics: ABO Blood-Group System; Blood Banks; Blood Cell Count; Blood Platelets; Blood Preservation; Blood Tr

1968

Other Studies

36 other studies available for glycerol and Hemoglobinuria

ArticleYear
Haemoglobinuria caused by propylene glycol in sheep.
    British journal of pharmacology and chemotherapy, 1958, Volume: 13, Issue:4

    Topics: Animals; Glycerol; Glycols; Hemoglobinuria; Injections, Intravenous; Pentobarbital; Propylene Glycol

1958
RECENT DIFFICULTIES WITH FROZEN GLYCEROLIZED BLOOD.
    JAMA, 1964, Jun-29, Volume: 188

    Topics: Acute Kidney Injury; Blood Transfusion; Cold Temperature; Erythrocytes; Freezing; Glycerol; Hemoglob

1964
STUDIES ON OXIDATIVE ENZYME SYSTEMS OF THE RAT KIDNEY AFTER HAEMOLYSIS AND HAEMOGLOBINURIA.
    Acta pathologica et microbiologica Scandinavica, 1964, Volume: 61

    Topics: Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Dihydrolipoamide Dehydrogenase; Electron Transp

1964
[MORPHOLOGY OF THE KIDNEY IN EXPERIMENTAL HEMOGLOBINURIC DUE TO GLYCEROL IN THE RAT. PHYSIOPATHOLOGIC AND HISTOPATHOGENETIC CORRELATIONS WITH HUMAN HEMOGLOBINURIA KIDNEY DISEASE (FAVISM, ETC.)].
    Archivio italiano di anatomia e istologia patologica, 1964, Volume: 38

    Topics: Favism; Glycerol; Hemoglobinuria; Humans; Kidney; Kidney Diseases; Rats; Research

1964
Toll-like receptor (TLR4) shedding and depletion: acute proximal tubular cell responses to hypoxic and toxic injury.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:1

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line; Cisplatin; Glycerol; Hemoglobinuria; H

2007
[Case of hemoglobinuria following glycerin enema].
    Masui. The Japanese journal of anesthesiology, 2007, Volume: 56, Issue:6

    Topics: Anesthesia, General; Diagnosis, Differential; Enema; Glycerol; Hemoglobinuria; Hemolysis; Humans; Lu

2007
Glycerol induced hemoglobinuric acute renal failure in the rat. II. The experimental model, predisposing factors, and pathophysiologic features.
    Nephron, 1967, Volume: 4, Issue:5

    Topics: Acute Kidney Injury; Animals; Blood Volume; Dehydration; Glycerol; Hemoglobinuria; Plasma Volume; Ra

1967
Glycerol induced hemoglobinuric acute renal failure in the rat. 3. Micropuncture study of the effects of mannitol and isotonic saline on individual nephron function.
    Nephron, 1967, Volume: 4, Issue:6

    Topics: Acute Kidney Injury; Animals; Female; Glycerol; Hemoglobinuria; Mannitol; Rats; Sodium Chloride

1967
Na intake, renal renin, and the severity of myohemoglobinuric renal failure in rats.
    The American journal of physiology, 1981, Volume: 241, Issue:1

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Female; Glycerol; Hematocrit; Hemoglobinuria; Kid

1981
Metabolic studies of glycerol-induced acute renal failure in the rat.
    Experimental and molecular pathology, 1981, Volume: 35, Issue:1

    Topics: Acute Kidney Injury; Adenine Nucleotides; Animals; Creatinine; Dihydroxyacetone; Disease Models, Ani

1981
Glomerular inflammation induces resistance to tubular injury in the rat. A novel form of acquired, heme oxygenase-dependent resistance to renal injury.
    The Journal of clinical investigation, 1996, Nov-01, Volume: 98, Issue:9

    Topics: Acute Kidney Injury; Animals; Enzyme Induction; Ferritins; Gene Expression Regulation, Enzymologic;

1996
Hypertonic glycerol therapy of cerebral edema and its possible side-effects.
    The Keio journal of medicine, 1979, Volume: 28, Issue:1

    Topics: Adult; Aged; Brain Edema; Female; Glycerol; Hemoglobinuria; Humans; Hypertonic Solutions; Infusions,

1979
The pathogenetic significance of intravascular coagulation in experimental acute renal failure.
    Nephron, 1978, Volume: 22, Issue:4-6

    Topics: Acute Kidney Injury; Animals; Blood Transfusion; Blood Urea Nitrogen; Disease Models, Animal; Dissem

1978
Natriuresis-induced protection in acute myohemoglobinuric renal failure without renal cortical renin content depletion in the rat.
    Nephron, 1978, Volume: 22, Issue:4-6

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chlorides; Disease Models, Animal; Female; Glycer

1978
Intravenous urography in experimental acute renal failure. Nephrograms and pyelograms in saline-loaded rats.
    Nephron, 1978, Volume: 22, Issue:4-6

    Topics: Acute Kidney Injury; Animals; Creatinine; Glycerol; Hemoglobinuria; Kidney; Kidney Tubular Necrosis,

1978
Active and passive immunization to angiotensin in experimental acute renal failure.
    Kidney international, 1975, Volume: 7, Issue:1

    Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Female; Glomerular Filtration Rate; Gl

1975
Resistance to acute renal failure afforded by prior renal failure: examination of the role of renal renin content.
    Nephron, 1975, Volume: 15, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Female; Glomerular Filtration Rate; Glycerol; Hem

1975
Acute renal insufficiency in the rabbit by glycerol.
    Revista espanola de fisiologia, 1975, Volume: 31, Issue:1

    Topics: Acute Kidney Injury; Animals; Carbon Dioxide; Disease Models, Animal; Glycerol; Glycosuria; Hemoglob

1975
Hemolytic transfusion reaction following transfusion of frozen and washed autologous red cells.
    Transfusion, 1991, Volume: 31, Issue:2

    Topics: Blood Preservation; Blood Transfusion, Autologous; Cryopreservation; Erythrocyte Transfusion; Glycer

1991
Effects of pentoxifylline in experimental acute renal failure.
    Kidney international, 1989, Volume: 36, Issue:3

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Glycerol; Hemogl

1989
Glycerol-induced acute renal failure in the rat: protection by exercise.
    Kidney international. Supplement, 1987, Volume: 22

    Topics: Acute Kidney Injury; Animals; Glycerol; Hemoglobinuria; Male; Physical Exertion; Rats; Rats, Inbred

1987
Glycerol-induced haemolysis with haemoglobinuria and acute renal failure. Report of three cases.
    Lancet (London, England), 1974, Jan-19, Volume: 1, Issue:7847

    Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Brain Edema; Brain Neoplasms; Female; Glycer

1974
Intravascular coagulation and glycerin hemoglobinuric acute renal failure.
    Archives of pathology, 1973, Volume: 95, Issue:4

    Topics: Acute Kidney Injury; Aminocaproates; Animals; Autoradiography; Disseminated Intravascular Coagulatio

1973
[Experimental hemoglobinuria induced by glycerol in the kidney in vicarious function after monolateral nephrectomy. I. Study with the optic microscope].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1968, Volume: 51, Issue:1

    Topics: Animals; Glycerol; Hemoglobinuria; Hypertrophy; Kidney; Male; Microscopy; Mitosis; Nephrectomy; Opti

1968
Experimental hemoglobinuric nephropathy. I. Comparative light microscopic, histochemical, and pathophysiologic studies.
    Virchows Archiv. B, Cell pathology, 1969, Volume: 3, Issue:2

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Bile Acids and Salts; Glycerol; Hemoglobins; Hemogl

1969
Experimental hemoglobinuric nephropathy. II. Electron microscopic studies.
    Virchows Archiv. B, Cell pathology, 1969, Volume: 3, Issue:2

    Topics: Animals; Bile Acids and Salts; Glycerol; Hemoglobins; Hemoglobinuria; Hemolysis; Histological Techni

1969
[Changes in the juxtaglomerular cells in experimental nephropathy induced with glycerol].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1969, Volume: 54, Issue:3

    Topics: Animals; Glycerol; Hemoglobinuria; Juxtaglomerular Apparatus; Kidney Diseases; Rabbits

1969
Resistance to glycerol induced hemoglobinuric acute renal failure.
    Nephron, 1970, Volume: 7, Issue:2

    Topics: Acute Kidney Injury; Animals; Chronic Disease; Disease Models, Animal; Diuresis; Female; Glycerol; H

1970
[Comparative research on hemoglobinuric nephrosis due to glycerol in the young and adult rabbit].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1967, Volume: 50, Issue:1

    Topics: Age Factors; Animals; Glycerol; Hemoglobinuria; Male; Nephrosis; Rabbits

1967
[Glycerol-induced experimental hemoglobinuria in the remaining kidney having a substitutive function after monolateral nephrectomy. II. Study with the electron microscope].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1968, Volume: 51, Issue:1

    Topics: Animals; Glycerol; Hemoglobinuria; Kidney; Male; Microscopy, Electron; Nephrectomy; Postoperative Co

1968
[Morphological changes in rabbit kidneys multiple crises of hemoglobinuria induced by prolonged therapy with glycerol. Study by optical and electronic microscope].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1968, Volume: 53, Issue:1

    Topics: Animals; Glycerol; Hemoglobinuria; Kidney; Male; Microscopy, Electron; Rabbits

1968
[Theory and value of glycerin therapy in urolithiasis].
    Deutsche medizinische Wochenschrift (1946), 1969, Jun-13, Volume: 94, Issue:24

    Topics: Adult; Aged; Clinical Enzyme Tests; Fasting; Female; Glycerol; Hemoglobinuria; Humans; Male; Mathema

1969
The role of the concentration mechanism in the development of acute renal failure: micropuncture studies using diabetes insipidus rats.
    Nephron, 1969, Volume: 6, Issue:2

    Topics: Acute Kidney Injury; Animals; Dehydration; Diabetes Insipidus; Glycerol; Hemoglobinuria; Kidney; Kid

1969
Biochemical mitochondrial renal damage in glycerol-induced haemoglobinuric nephrosis in the rat. Study of oxidative phosphorylation (succinate substrate) in the different stages of nephrosis and under various experimental conditions.
    Panminerva medica, 1965, Volume: 7, Issue:12

    Topics: Animals; Glycerol; Hemoglobinuria; Nephrosis; Oxidative Phosphorylation; Rats

1965
Hypotension and hemoglobinuria in rats following intravenous injections of hypertonic solutions.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 157, Issue:2

    Topics: Animals; Blood Pressure; Glucose; Glycerol; Hemoglobinuria; Hemolysis; Hypertonic Solutions; Hypoten

1965
Glycerol-induced hemoglobinuric acute renal failure in the rat. I. Micropuncture study of the development of oliguria.
    The Journal of clinical investigation, 1966, Volume: 45, Issue:5

    Topics: Acute Kidney Injury; Animals; Anuria; Female; Glomerular Filtration Rate; Glycerides; Glycerol; Hemo

1966