glycerol has been researched along with HIV-Associated Lipodystrophy Syndrome in 9 studies
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HIV-Associated Lipodystrophy Syndrome: Defective metabolism leading to fat maldistribution in patients infected with HIV. The etiology appears to be multifactorial and probably involves some combination of infection-induced alterations in metabolism, direct effects of antiretroviral therapy, and patient-related factors.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In eight HIV-1 infected men with lipodystrophy syndrome, we studied the effects of replacement of protease inhibitor (PI) by abacavir on insulin sensitivity and lipolysis by hyperinsulinemic euglycemic clamp and on fat distribution assessed by dual-energy x-ray absorptiometry and computed tomography scan." | 5.11 | Markedly diminished lipolysis and partial restoration of glucose metabolism, without changes in fat distribution after extended discontinuation of protease inhibitors in severe lipodystrophic human immunodeficient virus-1-infected patients. ( Ackermans, MT; Allick, G; Endert, E; Lange, JM; Reiss, P; Romijn, JA; Sauerwein, HP; van der Valk, M; van Eck-Smit, BL; van Kuijk, C; Weverling, GJ, 2004) |
| "Rosiglitazone treatment significantly increased both total lipolysis (R(a) FFA(total) from 3." | 1.37 | Effects of rosiglitazone on abnormal lipid kinetics in HIV-associated dyslipidemic lipodystrophy: a stable isotope study. ( Balasubramanyam, A; D'Amico, S; Jahoor, F; Patel, SG; Rehman, K; Sekhar, RV; Shi, J; Visnegarwala, F, 2011) |
| "Glycerol release was higher in both HIV-infected groups, especially those without fat redistribution." | 1.32 | Studies of adipose tissue metabolism in human immunodeficiency virus-associated lipodystrophy. ( Albu, JB; Engelson, ES; He, Q; Inada, Y; Ionescu, G; Johnson, JA; Kotler, DP, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sekhar, RV | 1 |
| Patel, SG | 1 |
| D'Amico, S | 1 |
| Shi, J | 1 |
| Balasubramanyam, A | 1 |
| Rehman, K | 1 |
| Jahoor, F | 1 |
| Visnegarwala, F | 1 |
| Magkos, F | 1 |
| Mantzoros, CS | 1 |
| Kotler, DP | 1 |
| Ionescu, G | 1 |
| Johnson, JA | 1 |
| Inada, Y | 1 |
| He, Q | 1 |
| Engelson, ES | 1 |
| Albu, JB | 1 |
| Weis, BC | 1 |
| Margolis, D | 1 |
| Burgess, SC | 1 |
| Merritt, ME | 1 |
| Wise, H | 1 |
| Sherry, AD | 1 |
| Malloy, CR | 1 |
| van der Valk, M | 1 |
| Allick, G | 1 |
| Weverling, GJ | 1 |
| Romijn, JA | 1 |
| Ackermans, MT | 1 |
| Lange, JM | 1 |
| van Eck-Smit, BL | 1 |
| van Kuijk, C | 1 |
| Endert, E | 1 |
| Sauerwein, HP | 2 |
| Reiss, P | 2 |
| Haugaard, SB | 3 |
| Andersen, O | 3 |
| Dela, F | 2 |
| Holst, JJ | 1 |
| Storgaard, H | 1 |
| Fenger, M | 2 |
| Iversen, J | 3 |
| Madsbad, S | 3 |
| Pedersen, SB | 2 |
| Richelsen, B | 2 |
| Svenstrup, B | 1 |
| Hansen, BR | 1 |
| Paulsen, SK | 1 |
| Rathje, GS | 1 |
| Nielsen, JO | 1 |
| Blümer, RM | 1 |
| van Vonderen, MG | 1 |
| Sutinen, J | 1 |
| Hassink, E | 1 |
| Ackermans, M | 1 |
| van Agtmael, MA | 1 |
| Yki-Jarvinen, H | 1 |
| Danner, SA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Low-Dose Human Growth Hormone Therapy in HIV Infected Patients on Highly Active Antiretroviral Therapy (HAART)[NCT00119769] | Phase 4 | 46 participants (Actual) | Interventional | 2005-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for glycerol and HIV-Associated Lipodystrophy Syndrome
| Article | Year |
|---|---|
Markedly diminished lipolysis and partial restoration of glucose metabolism, without changes in fat distribution after extended discontinuation of protease inhibitors in severe lipodystrophic human immunodeficient virus-1-infected patients.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Anti-HIV Agents; Body Composition; Dideoxynucleosides | 2004 |
Zidovudine/lamivudine contributes to insulin resistance within 3 months of starting combination antiretroviral therapy.
Topics: Adiponectin; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Glucos | 2008 |
7 other studies available for glycerol and HIV-Associated Lipodystrophy Syndrome
| Article | Year |
|---|---|
Effects of rosiglitazone on abnormal lipid kinetics in HIV-associated dyslipidemic lipodystrophy: a stable isotope study.
Topics: Antiretroviral Therapy, Highly Active; Blood Glucose; Body Composition; Calorimetry, Indirect; Fatty | 2011 |
Body fat redistribution and metabolic abnormalities in HIV-infected patients on highly active antiretroviral therapy: novel insights into pathophysiology and emerging opportunities for treatment.
Topics: Adiponectin; Adipose Tissue; Antiretroviral Therapy, Highly Active; Dyslipidemias; Fatty Acids, None | 2011 |
Studies of adipose tissue metabolism in human immunodeficiency virus-associated lipodystrophy.
Topics: Adipose Tissue; Adult; Anti-HIV Agents; Blood Proteins; Body Composition; Complement C3a; Cross-Sect | 2003 |
Glucose production pathways by 2H and 13C NMR in patients with HIV-associated lipoatrophy.
Topics: Acetaminophen; Blood Glucose; Carbon Isotopes; Citric Acid Cycle; Deuterium; Fasting; Female; Glucon | 2004 |
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.
Topics: Adult; Alanine; Antiretroviral Therapy, Highly Active; Blood Glucose; Body Composition; Cholesterol, | 2005 |
Tumor necrosis factor alpha is associated with insulin-mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy.
Topics: Adipose Tissue; Adult; Blood Glucose; Body Composition; Cross-Sectional Studies; Fatty Acids, Nonest | 2006 |
Circulating sex hormones and gene expression of subcutaneous adipose tissue oestrogen and alpha-adrenergic receptors in HIV-lipodystrophy: implications for fat distribution.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aromatase; Body Composition; Cross-Sectional | 2007 |