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glycerol and Elevated ICP (Intracranial Pressure)

glycerol has been researched along with Elevated ICP (Intracranial Pressure) in 21 studies

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Research Excerpts

ExcerptRelevanceReference
"The present study was performed to assess the prophylactic effect of baicalin, a flavonoid compound, in an animal model of heatstroke."7.74The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. ( Chang, CP; Cheng, BC; Hsu, CC; Huang, WT; Lin, MT, 2007)
"We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model."7.73Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005)
"In contrast, all vehicle-treated heatstroke animals had lower levels of MAP, cerebral perfusion pressure, cerebral blood flow, and brain partial pressure of oxygen."5.35L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke. ( Chen, YC; Huang, CI; Lee, CH; Lin, MT; Liu, YC; Wang, LM; Yen, DH, 2008)
"The present study was performed to assess the prophylactic effect of baicalin, a flavonoid compound, in an animal model of heatstroke."3.74The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. ( Chang, CP; Cheng, BC; Hsu, CC; Huang, WT; Lin, MT, 2007)
"An LP ratio >25 and glycerol >100 micromol/L, but not glutamate >12 micromol/L, were associated with significantly higher risk of imminent intracranial hypertension (odds ratio: 9."3.74Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study. ( Belli, A; Kitchen, N; Petzold, A; Russo, S; Sen, J; Smith, M, 2008)
"We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model."3.73Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005)
"Glycerol has been associated with membrane degradation and may support glycerol as a biomarker for vascular endothelial breakdown."2.90Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury. ( Eklund, A; Hägglund, L; Koskinen, LD; Olivecrona, M; Sundström, N, 2019)
"Oral glycerol was associated with lower mortality and neurological sequelae when compared to placebo in children with acute bacterial meningitis."2.46The role for osmotic agents in children with acute encephalopathies: a systematic review. ( Gatakaa, H; Gwer, S; Idro, R; Mwai, L; Newton, CR, 2010)
"When biochemical signs of cerebral ischemia progressed, i."1.37Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue. ( Nordström, CH; Reinstrup, P, 2011)
"In contrast, all vehicle-treated heatstroke animals had lower levels of MAP, cerebral perfusion pressure, cerebral blood flow, and brain partial pressure of oxygen."1.35L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke. ( Chen, YC; Huang, CI; Lee, CH; Lin, MT; Liu, YC; Wang, LM; Yen, DH, 2008)
"Brain metastasis from ovarian cancer, a rare and highly dismal event, develops mostly during or after postoperative chemotherapy."1.30Brain metastasis as first manifestation of ovarian cancer. ( Imai, A; Matsunami, K; Noda, K; Takagi, H; Tamaya, T, 1999)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's10 (47.62)29.6817
2010's5 (23.81)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Wang, J1
Ren, Y1
Wang, SF1
Kan, LD1
Zhou, LJ1
Fang, HM1
Fan, H1
Singhi, S1
Angurana, SK1
Patil, H1
Gupta, R1
Koskinen, LD1
Sundström, N1
Hägglund, L1
Eklund, A1
Olivecrona, M1
Nagel, A1
Graetz, D1
Schink, T1
Frieler, K1
Sakowitz, O1
Vajkoczy, P1
Sarrafzadeh, A1
Gwer, S1
Gatakaa, H1
Mwai, L1
Idro, R1
Newton, CR1
Reinstrup, P1
Nordström, CH2
Kalita, J1
Ranjan, P1
Misra, UK1
Chang, CP2
Chen, SH1
Lin, MT3
Salci, K1
Nilsson, P1
Goiny, M1
Contant, C1
Piper, I1
Enblad, P1
Huang, WT1
Cheng, BC1
Hsu, CC1
Chen, YC1
Liu, YC1
Yen, DH1
Wang, LM1
Huang, CI1
Lee, CH1
Zoremba, N1
Schnoor, J1
Berens, M1
Kuhlen, R1
Rossaint, R1
Belli, A1
Sen, J1
Petzold, A1
Russo, S1
Kitchen, N1
Smith, M1
Biestro, A1
Alberti, R1
Galli, R1
Cancela, M1
Soca, A1
Panzardo, H1
Borovich, B1
Prange, HW1
Nau, R1
Tateishi, A1
Soejima, Y1
Taira, Y1
Nakashima, K1
Fujisawa, H1
Tsuchida, E1
Maekawa, T1
Ito, H1
Takagi, H2
Tsuyusaki, H1
Endo, M1
Kitahara, T1
Matsunami, K1
Imai, A1
Tamaya, T1
Noda, K1
Schneweis, S1
Grond, M1
Staub, F1
Brinker, G1
Neveling, M1
Dohmen, C1
Graf, R1
Heiss, WD1

Reviews

6 reviews available for glycerol and Elevated ICP (Intracranial Pressure)

ArticleYear
Comparative efficacy and safety of glycerol versus mannitol in patients with cerebral oedema and elevated intracranial pressure: A systematic review and meta-analysis.
    Journal of clinical pharmacy and therapeutics, 2021, Volume: 46, Issue:2

    Topics: Brain Edema; China; Diuretics, Osmotic; Glycerol; Humans; Intracranial Hypertension; Mannitol; Rando

2021
Principles of Management of Central Nervous System Infections.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:1

    Topics: Anti-Infective Agents; Anticonvulsants; Central Nervous System Infections; Chemoprevention; Child; E

2019
The role for osmotic agents in children with acute encephalopathies: a systematic review.
    BMC pediatrics, 2010, Apr-17, Volume: 10

    Topics: Acute Disease; Brain Diseases; Child; Diuretics, Osmotic; Glycerol; Humans; Intracranial Hypertensio

2010
Current status of osmotherapy in intracerebral hemorrhage.
    Neurology India, 2003, Volume: 51, Issue:1

    Topics: Cerebral Hemorrhage; Diuretics, Osmotic; Glycerol; Humans; Intracranial Hypertension; Mannitol; Sali

2003
Assessment of critical thresholds for cerebral perfusion pressure by performing bedside monitoring of cerebral energy metabolism.
    Neurosurgical focus, 2003, Dec-15, Volume: 15, Issue:6

    Topics: Blood Pressure; Blood-Brain Barrier; Body Water; Brain; Brain Chemistry; Brain Edema; Brain Injuries

2003
[Pharmacodynamics and pharmacokinetics of therapeutic osmoregulating agents in increased intracranial pressure].
    Zentralblatt fur Neurochirurgie, 1997, Volume: 58, Issue:3

    Topics: Animals; Blood-Brain Barrier; Diuretics, Osmotic; Glycerol; Humans; Intracranial Hypertension; Manni

1997

Trials

4 trials available for glycerol and Elevated ICP (Intracranial Pressure)

ArticleYear
A Comparative Study of Bolus Dose of Hypertonic Saline, Mannitol, and Mannitol Plus Glycerol Combination in Patients with Severe Traumatic Brain Injury.
    World neurosurgery, 2019, Volume: 125

    Topics: Adolescent; Adult; Aged; Brain Injuries, Traumatic; Diuretics, Osmotic; Drug Therapy, Combination; G

2019
Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury.
    Neurocritical care, 2019, Volume: 31, Issue:3

    Topics: Adult; Antihypertensive Agents; Arterial Pressure; Blood Pressure; Brain; Brain Injuries, Traumatic;

2019
Osmotherapy for increased intracranial pressure: comparison between mannitol and glycerol.
    Acta neurochirurgica, 1997, Volume: 139, Issue:8

    Topics: Adolescent; Adult; Brain Injuries; Female; Follow-Up Studies; Glasgow Coma Scale; Glycerol; Humans;

1997
Predictive value of neurochemical monitoring in large middle cerebral artery infarction.
    Stroke, 2001, Volume: 32, Issue:8

    Topics: Adult; Aged; Brain Edema; Critical Care; Electrodes, Implanted; Extracellular Space; Female; Frontal

2001

Other Studies

11 other studies available for glycerol and Elevated ICP (Intracranial Pressure)

ArticleYear
Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage. Clinical article.
    Journal of neurosurgery, 2009, Volume: 111, Issue:1

    Topics: Adult; Brain; Brain Diseases; Craniotomy; Decompression, Surgical; Energy Metabolism; Female; Glutam

2009
Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue.
    Neurocritical care, 2011, Volume: 14, Issue:3

    Topics: Blood Glucose; Brain Concussion; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Epoprostenol; F

2011
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:4

    Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid;

2005
Low intracranial compliance increases the impact of intracranial volume insults to the traumatized brain: a microdialysis study in a traumatic brain injury rodent model.
    Neurosurgery, 2006, Volume: 59, Issue:2

    Topics: Animals; Biomarkers; Brain; Brain Chemistry; Brain Edema; Brain Injuries; Cell Membrane; Cerebral He

2006
The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
    Neuropharmacology, 2007, Volume: 52, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Brain Chemistry; Catechols; Cytoki

2007
L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:2

    Topics: Animals; Arginine; Cerebrovascular Circulation; Cerebrovascular Disorders; Cytokines; Encephalitis;

2008
Brain metabolism during a decrease in cerebral perfusion pressure caused by an elevated intracranial pressure in the porcine neocortex.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:3

    Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Glucose; Glutamic Acid

2007
Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study.
    Acta neurochirurgica, 2008, Volume: 150, Issue:5

    Topics: Biomarkers; Brain; Brain Injuries; Glutamic Acid; Glycerol; Humans; Intracranial Hypertension; Lacti

2008
Feasibility of the titration method of mild hypothermia in severely head-injured patients with intracranial hypertension.
    Neurosurgery, 1998, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Aged; Brain Damage, Chronic; Brain Injuries; Combined Modality Therapy; Cross Inf

1998
Pharmacokinetics of serum glycerol and changes of ICP: comparison of gastric and duodenal administration.
    Acta neurochirurgica. Supplement, 1998, Volume: 71

    Topics: Brain Injuries; Enteral Nutrition; Glycerol; Humans; Intracranial Hypertension; Intracranial Pressur

1998
Brain metastasis as first manifestation of ovarian cancer.
    European journal of obstetrics, gynecology, and reproductive biology, 1999, Volume: 82, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Endometrioid; Cis

1999