glycerol and Discitis

glycerol has been researched along with Discitis in 1 studies

Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.

Discitis: Inflammation of an INTERVERTEBRAL DISC or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

Research

Studies (1)

Authors

Clinical Trials (1)

Trial Overview

Trial Outcomes

Change From Baseline in Pain Scores on the Visual Analog Scale (VAS) at 24 Months

VAS scale ranged from 0 to 100mm with the 100mm accounting for the highest level of pain (NCT02064855)
Timeframe: Baseline (up to 8 weeks post-operatively) to 24 months

Change From Baseline in Quality of Life Scores on the SF-12v2 at 24 Months

SF-12v2 ranged between 0 and 100 points. The higher the points the better the self-assessed quality of life. (NCT02064855)
Timeframe: Baseline (up to 8 weeks post-operatively) to 24 months

Estimated Blood Loss

The amount of blood loss over the entire length of the surgery (NCT02064855)
Timeframe: At time of surgery

Length of Anesthesia Time

The length of time the patient is under anesthesia. (NCT02064855)
Timeframe: At time of surgery

Length of Hospital Stay

The length of the hospital stay from the date of admission to the date of discharge . (NCT02064855)
Timeframe: Admission to discharge

Length of Surgery Time

The length of the surgical procedure from the initial incision to final closure. (NCT02064855)
Timeframe: At time of surgery

Change From Baseline in Daily Functional Ability Scores on the Oswestry Disability Index (ODI)

This patient-reported outcome measure is a 10 item questionnaire that evaluates disability and functional impairment associated with back problems. Each item is scored from 0 up to 5, with higher scores corresponding to greater disability. A total ODI score is determined by adding the scores of the individual questions and dividing that total by the maximum possible score (i.e., 50 if all questions are answered) to yield a percentage. Therefore, the ODI score ranges from 0% to 100%. (NCT02064855)
Timeframe: Baseline (Pre-Op), 24 months

Number of Participants With Adverse Events

All adverse events will be documented including device related, procedure related and additional serious adverse events. (NCT02064855)
Timeframe: 24 months

Patient Satisfaction

Patient Satisfaction at 12 Mo and 24 Mo (NCT02064855)
Timeframe: 12 months, 24 months

Radiographic Assessments

"X-rays at post operative include: AP& Lateral; Flex/Ext & Oblique X-rays. Radiographic assessments being performed include:~Device Condition Device Subsidence Device Migration" (NCT02064855)
Timeframe: 12 Months and 24 Months

Radiographic Assessments

"X-rays at pre-operative and post operative include: AP& Lateral; Flex/Ext & Oblique X-rays. Radiographic assessments being performed include:~Posterior/Transverse process fusion, Right side (by level)~Posterior/Transverse process fusion, Left side (by level)~Anterior fusion, if TLIF procedure done, by level~Overall fusion by level~Device Condition~Device Subsidence~Device Migration" (NCT02064855)
Timeframe: 12m

Use of Narcotics Post-surgery

The types and dosages of any narcotics taken by the patient post-surgery will be documented. (NCT02064855)
Timeframe: Pre-Op to 24 months

Trials

1 trial available for glycerol and Discitis