glycerol has been researched along with Diabetes Mellitus, Type 1 in 126 studies
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Plasma triglyceride saturation was similar between groups, but palmitoleic acid in plasma triglyceride was inversely related to adipocyte insulin sensitivity." | 9.17 | The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes. ( Bergman, BC; Clement, TW; Eckel, RH; Howard, D; Maahs, DM; Perreault, L; Rewers, M; Schauer, IE; Snell-Bergeon, JK, 2013) |
| "The objective was to assess glucose, lactate, glycerol, and pyruvate concentrations in the interstitial fluid of the adipose tissue as well as the glucose relative recovery coefficient in reference to capillary blood (RC) during the first two days of the standard treatment of diabetic ketoacidosis (DKA) in patients with type 1 and type 2 diabetes." | 7.79 | Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2013) |
| "To evaluate the role of glucagon in the pathogenesis of diabetic ketoacidosis in man, we studied the effect of suppression of glucagon secretion by somatostatin on changes in plasma beta-hydroxybutyrate and glucose concentrations (as well as changes in their precursors) after acute withdrawal of insulin from seven patients with juvenile-type diabetes." | 7.65 | Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon. ( Bier, DM; Forsham, PH; Gerich, JE; Karam, JH; Lorenzi, M; Schneider, V; Tsalikian, E, 1975) |
| " Plasma triglyceride saturation was similar between groups, but palmitoleic acid in plasma triglyceride was inversely related to adipocyte insulin sensitivity." | 5.17 | The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes. ( Bergman, BC; Clement, TW; Eckel, RH; Howard, D; Maahs, DM; Perreault, L; Rewers, M; Schauer, IE; Snell-Bergeon, JK, 2013) |
| "Our observations of an increased glucose requirement during the clamp as well as a decrease in haemoglobin A1c demonstrate improved insulin sensitivity in the adolescent girls with diabetes following pirenzepine therapy." | 5.10 | Insulin sensitivity and lipolysis in adolescent girls with poorly controlled type 1 diabetes: effect of anticholinergic treatment. ( Brismar, K; Gustafsson, J; Halldin, MU; Tuvemo, T, 2002) |
| "Leptin can reverse hyperglycemia in rodent models of type 1 diabetes." | 3.83 | Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy. ( Covey, SD; Denroche, HC; Kieffer, TJ; Mojibian, M; Neumann, UH, 2016) |
| "The objective was to assess glucose, lactate, glycerol, and pyruvate concentrations in the interstitial fluid of the adipose tissue as well as the glucose relative recovery coefficient in reference to capillary blood (RC) during the first two days of the standard treatment of diabetic ketoacidosis (DKA) in patients with type 1 and type 2 diabetes." | 3.79 | Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2013) |
| " Glycerol in T2DM microdialysate (but not in T1DM) was higher than in healthy volunteers, which is likely explained by sc insulin resistance (insulin is a potent antilipolytic hormone)." | 3.76 | Analyte flux at a biomaterial-tissue interface over time: implications for sensors for type 1 and 2 diabetes mellitus. ( Adamson, U; Brismar, K; Ekberg, NR; Hedblad, MA; Malmstedt, J; Ungerstedt, U; Wisniewski, N, 2010) |
| " During hypoglycemia, hormonal counterregulation was blunted in T1DM (peak: glucagon, 68 +/- 4 vs." | 3.73 | The role of intramyocellular lipids during hypoglycemia in patients with intensively treated type 1 diabetes. ( Anderwald, C; Bernroider, E; Brehm, A; Cline, G; Krssak, M; Roden, M; Shulman, GI; Trajanoski, Z, 2005) |
| "To evaluate the role of glucagon in the pathogenesis of diabetic ketoacidosis in man, we studied the effect of suppression of glucagon secretion by somatostatin on changes in plasma beta-hydroxybutyrate and glucose concentrations (as well as changes in their precursors) after acute withdrawal of insulin from seven patients with juvenile-type diabetes." | 3.65 | Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon. ( Bier, DM; Forsham, PH; Gerich, JE; Karam, JH; Lorenzi, M; Schneider, V; Tsalikian, E, 1975) |
| "People with type 1 diabetes (T1D) develop an impaired glucagon response to hypoglycaemia within 5 years of diagnosis, increasing their risk of severe hypoglycaemia." | 3.11 | Study protocol: a randomised controlled proof-of-concept real-world study - does maximising time in range using hybrid closed loop insulin delivery and a low carbohydrate diet restore the glucagon response to hypoglycaemia in adults with type 1 diabetes? ( Baillie, N; Baxter, F; Forbes, S, 2022) |
| "Twelve people with type 1 diabetes received, in random order, 0." | 2.80 | Effect of subcutaneous insulin detemir on glucose flux, lipolysis and electroencephalography in type 1 diabetes. ( Dijk, DJ; Herring, R; Jackson, N; Johnsen, S; Jones, R; Knight, R; Russell-Jones, DL; Shojaee-Moradie, F; Umpleby, AM, 2015) |
| "Eighteen patients with type 1 diabetes mellitus (mean age 36." | 2.73 | Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study. ( Bock, G; Bodenlenz, M; Fürst-Recktenwald, S; Horvath, K; Magnes, C; Pieber, TR; Plank, J; Regittnig, W; Sinner, F; Theobald, K; Wutte, A, 2008) |
| "Glycerol concentration was 267 +/- 41 micromol/L and 133 +/- 40 micromol/L in PF and venous blood, respectively (P = 0." | 2.73 | Microdialysis technique as a monitoring system for acute complications of diabetes. ( Ciechanowska, A; Foltynski, P; Karnafel, W; Kawiak, J; Krzymien, J; Ladyzynski, P; Pulawska, E; Sabalinska, S; Wojcicki, JM, 2008) |
| "Insulin-dependent diabetes mellitus (IDDM) is characterized by a metabolic and hormonal disarray that may be more evident during exercise." | 1.29 | Lipid and carbohydrate metabolism in IDDM during moderate and intense exercise. ( Bastyr, EJ; Coggan, AR; Gastaldelli, A; Raguso, CA; Sidossis, LS; Wolfe, RR, 1995) |
| "Six adult patients with IDDM were studied on conventional insulin therapy and after 2 mo of intensive insulin therapy while maintaining constant caloric intake and were compared with a group of 6 matched nondiabetic volunteers." | 1.29 | Intensive insulin therapy and weight gain in IDDM. ( Campbell, PJ; Carlson, MG, 1993) |
| "From 1981 to 1994, 112 IDDM patients were on IT." | 1.29 | Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia. ( Annibale, B; Bartocci, L; Bolli, GB; Brunetti, P; Ciofetta, M; Di Vincenzo, A; Epifano, L; Fanelli, C; Lalli, C; Lepore, M; Modarelli, F; Pampanelli, S; Rambotti, AM; Sindaco, PD, 1996) |
| " Dose-response curves were constructed for insulin-stimulated glucose disposal." | 1.28 | Insulin resistance in type 1 (insulin-dependent) diabetes: dissimilarities for glucose and intermediary metabolites. ( Krans, HM; Nijs, HG; Poorthuis, BJ; Radder, JK, 1990) |
| "The patients with IDDM exhibited threefold greater increments in plasma glucose, largely the result of greater increments in glucose production." | 1.27 | Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine ( Berk, MA; Clutter, WE; Cryer, PE; Gingerich, RP; Parvin, CA; Shah, SD; Skor, D, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (46.03) | 18.7374 |
| 1990's | 39 (30.95) | 18.2507 |
| 2000's | 15 (11.90) | 29.6817 |
| 2010's | 12 (9.52) | 24.3611 |
| 2020's | 2 (1.59) | 2.80 |
| Authors | Studies |
|---|---|
| Baxter, F | 1 |
| Baillie, N | 1 |
| Forbes, S | 1 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 7 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Zhang, H | 1 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
| Pickersgill, NA | 1 |
| Vetter, JM | 1 |
| Kim, EH | 1 |
| Cope, SJ | 1 |
| Du, K | 1 |
| Venkatesh, R | 1 |
| Giardina, JD | 1 |
| Saad, NES | 1 |
| Bhayani, SB | 1 |
| Figenshau, RS | 1 |
| Eriksson, J | 1 |
| Landfeldt, E | 1 |
| Ireland, S | 1 |
| Jackson, C | 1 |
| Wyatt, E | 1 |
| Gaudig, M | 1 |
| Stancill, JS | 1 |
| Happ, JT | 1 |
| Broniowska, KA | 1 |
| Hogg, N | 1 |
| Corbett, JA | 1 |
| Tang, LF | 1 |
| Bi, YL | 1 |
| Fan, Y | 2 |
| Sun, YB | 1 |
| Wang, AL | 1 |
| Xiao, BH | 1 |
| Wang, LF | 1 |
| Qiu, SW | 1 |
| Guo, SW | 1 |
| Wáng, YXJ | 1 |
| Sun, J | 2 |
| Chu, S | 1 |
| Pan, Q | 1 |
| Li, D | 2 |
| Zheng, S | 2 |
| Ma, L | 1 |
| Wang, L | 3 |
| Hu, T | 1 |
| Wang, F | 1 |
| Han, Z | 1 |
| Yin, Z | 1 |
| Ge, X | 1 |
| Xie, K | 1 |
| Lei, P | 1 |
| Dias-Santagata, D | 1 |
| Lennerz, JK | 1 |
| Sadow, PM | 1 |
| Frazier, RP | 1 |
| Govinda Raju, S | 1 |
| Henry, D | 1 |
| Chung, T | 1 |
| Kherani, J | 1 |
| Rothenberg, SM | 1 |
| Wirth, LJ | 1 |
| Marti, CN | 1 |
| Choi, NG | 1 |
| Bae, SJ | 1 |
| Ni, L | 1 |
| Luo, X | 1 |
| Dai, T | 1 |
| Yang, Y | 3 |
| Lee, R | 1 |
| Fleischer, AS | 1 |
| Wemhoff, AP | 1 |
| Ford, CR | 1 |
| Kleppinger, EL | 1 |
| Helms, K | 1 |
| Bush, AA | 1 |
| Luna-Abanto, J | 1 |
| García Ruiz, L | 1 |
| Laura Martinez, J | 1 |
| Álvarez Larraondo, M | 1 |
| Villoslada Terrones, V | 1 |
| Dukic, L | 1 |
| Maric, N | 1 |
| Simundic, AM | 1 |
| Chogtu, B | 1 |
| Ommurugan, B | 1 |
| Thomson, SR | 1 |
| Kalthur, SG | 1 |
| Benidir, M | 1 |
| El Massoudi, S | 1 |
| El Ghadraoui, L | 1 |
| Lazraq, A | 1 |
| Benjelloun, M | 1 |
| Errachidi, F | 1 |
| Cassar, M | 1 |
| Law, AD | 1 |
| Chow, ES | 1 |
| Giebultowicz, JM | 1 |
| Kretzschmar, D | 1 |
| Salonurmi, T | 1 |
| Nabil, H | 1 |
| Ronkainen, J | 1 |
| Hyötyläinen, T | 1 |
| Hautajärvi, H | 1 |
| Savolainen, MJ | 1 |
| Tolonen, A | 1 |
| Orešič, M | 1 |
| Känsäkoski, P | 1 |
| Rysä, J | 1 |
| Hakkola, J | 1 |
| Hukkanen, J | 1 |
| Zhu, N | 1 |
| Li, Y | 4 |
| Du, Q | 1 |
| Hao, P | 1 |
| Cao, X | 1 |
| Li, CX | 1 |
| Zhao, S | 1 |
| Luo, XM | 1 |
| Feng, JX | 1 |
| Gonzalez-Cotto, M | 1 |
| Guo, L | 1 |
| Karwan, M | 1 |
| Sen, SK | 1 |
| Barb, J | 1 |
| Collado, CJ | 1 |
| Elloumi, F | 1 |
| Palmieri, EM | 1 |
| Boelte, K | 1 |
| Kolodgie, FD | 1 |
| Finn, AV | 1 |
| Biesecker, LG | 1 |
| McVicar, DW | 1 |
| Qu, F | 1 |
| Deng, Z | 1 |
| Xie, Y | 2 |
| Tang, J | 3 |
| Chen, Z | 2 |
| Luo, W | 1 |
| Xiong, D | 1 |
| Zhao, D | 1 |
| Fang, J | 1 |
| Zhou, Z | 1 |
| Niu, PP | 1 |
| Song, B | 1 |
| Xu, YM | 1 |
| Zhang, Z | 2 |
| Qiu, N | 1 |
| Yin, J | 1 |
| Zhang, J | 3 |
| Guo, W | 1 |
| Liu, M | 2 |
| Liu, T | 2 |
| Chen, D | 5 |
| Luo, K | 1 |
| He, Z | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Placebo-controlled, Double-blinded Cross-over Study of the Pharmacologic Action of a GPR119 Agonist on Glucagon Counter-regulation During Insulin-induced Hypoglycemia in Type 1 Diabetes Mellitus[NCT04432090] | Phase 2 | 67 participants (Actual) | Interventional | 2021-04-21 | Active, not recruiting | ||
| [NCT01739283] | 10 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| The Effect of Type 1 Diabetes on Pan-Arterial Vascular Function and Insulin Sensitivity in Humans[NCT02490124] | 7 participants (Actual) | Observational | 2014-12-31 | Completed | |||
| The Impact of Fitness and Mineralocorticoid Receptor Blockade on Vascular Dysfunction in Adults With Type 1 Diabetes[NCT03174288] | 32 participants (Actual) | Interventional | 2015-08-31 | Completed | |||
| Metformin Therapy for Overweight Adolescents With Type 1 Diabetes (T1D)--Insulin Clamp Ancillary Study for Assessment of Insulin Resistance[NCT02045290] | Phase 3 | 37 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| A Randomized Trial of Metformin as Adjunct Therapy for Overweight Adolescents With Type 1 Diabetes[NCT01881828] | Phase 3 | 164 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Prospective Randomized Trial of Polymem vs. Bacitracin/Xeroform for Superficial Second Degree Burns[NCT00479193] | Phase 1 | 0 participants (Actual) | Interventional | 2006-10-31 | Withdrawn | ||
| The Influence of Glycemic Control and Obesity on Energy Balance and Metabolic Flexibility in Type 1 Diabetes[NCT03379792] | 29 participants (Actual) | Interventional | 2018-03-08 | Active, not recruiting | |||
| The Role of ATGL and G0/G1 Switch Gene Complex in Lipopolysaccaride (LPS) Induced Ketosis - a Controlled, Randomised, Clinical Experimental Study[NCT02157155] | 9 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in percent body fat (NCT01881828)
Timeframe: 0-26 weeks
| Intervention | percentage of change (Mean) |
|---|---|
| Metformin | -0 |
| Oral Placebo | 1 |
(NCT01881828)
Timeframe: 0-26 weeks
| Intervention | percentile (Mean) |
|---|---|
| Metformin | -1 |
| Oral Placebo | 1 |
(NCT01881828)
Timeframe: 0-26 weeks
| Intervention | insulin per kg (Mean) |
|---|---|
| Metformin | -0.1 |
| Oral Placebo | -0.0 |
(NCT01881828)
Timeframe: 0-26 weeks
| Intervention | centimeters (Mean) |
|---|---|
| Metformin | -0 |
| Oral Placebo | 1 |
(NCT01881828)
Timeframe: 0-26 weeks
| Intervention | mm Hg (Mean) | |
|---|---|---|
| Change in Systolic | Change in Diastolic | |
| Metformin | 0 | 0 |
| Oral Placebo | -0 | 0 |
Hemoglobin A1c is a measure of glycemic control over approximately the past 3 months (NCT01881828)
Timeframe: 0-26 weeks
| Intervention | percentage (Mean) | |
|---|---|---|
| HbA1c | Change from Baseline to 26 Weeks | |
| Metformin | 9.0 | 0.2 |
| Oral Placebo | 8.9 | 0.2 |
Hemoglobin A1c is a measure of glycemic control over approximately the past 3 months (NCT01881828)
Timeframe: 0-26 weeks
| Intervention | percentage of participants (Number) | ||
|---|---|---|---|
| HbA1c Decrease ≥0.5% | HbA1c Increase ≥0.5% | HbA1c <7.5% | |
| Metformin | 19 | 44 | 3 |
| Oral Placebo | 18 | 35 | 4 |
(NCT01881828)
Timeframe: 0-26 weeks
| Intervention | mg/dL (Mean) | ||||
|---|---|---|---|---|---|
| Change in LDL | Change in VLDL | Change in HDL | Change in Triglycerides | Change in Total Cholesterol | |
| Metformin | -6 | -0 | -0 | 4 | -5 |
| Oral Placebo | 2 | 1 | -1 | 6 | 3 |
3 reviews available for glycerol and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
beta-adrenergic blockade and diabetes mellitus. A review.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; D | 1983 |
Renal glucose production and utilization: new aspects in humans.
Topics: Animals; Diabetes Mellitus, Type 1; Epinephrine; Glucagon; Gluconeogenesis; Glucose; Glycerol; Human | 1997 |
26 trials available for glycerol and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Study protocol: a randomised controlled proof-of-concept real-world study - does maximising time in range using hybrid closed loop insulin delivery and a low carbohydrate diet restore the glucagon response to hypoglycaemia in adults with type 1 diabetes?
Topics: Adult; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Diet, Carbohydrate-R | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Glycerol Potentiates the Effects of Glucose in Promoting Glucose Recovery During Hypoglycemia: From Basic to Clinical Investigations and Their Therapeutic Application.
Topics: Animals; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Glucose; Glycerol; | 2021 |
Glucose-dependent insulinotropic polypeptide augments glucagon responses to hypoglycemia in type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; | 2015 |
Glucose-dependent insulinotropic polypeptide augments glucagon responses to hypoglycemia in type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; | 2015 |
Glucose-dependent insulinotropic polypeptide augments glucagon responses to hypoglycemia in type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; | 2015 |
Glucose-dependent insulinotropic polypeptide augments glucagon responses to hypoglycemia in type 1 diabetes.
Topics: Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind Method; | 2015 |
Effect of subcutaneous insulin detemir on glucose flux and lipolysis during hyperglycaemia in people with type 1 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Glycated Hemoglobin; Glycerol; Hum | 2015 |
Effect of subcutaneous insulin detemir on glucose flux, lipolysis and electroencephalography in type 1 diabetes.
Topics: Adult; Blood Glucose; Brain; Cross-Over Studies; Diabetes Mellitus, Type 1; Electroencephalography; | 2015 |
Reduced peripheral activity leading to hepato-preferential action of basal insulin peglispro compared with insulin glargine in patients with type 1 diabetes.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glu | 2016 |
The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes.
Topics: Adipocytes; Adult; Diabetes Mellitus, Type 1; Fatty Acids, Monounsaturated; Female; Glucose Clamp Te | 2013 |
Insulin sensitivity and lipolysis in adolescent girls with poorly controlled type 1 diabetes: effect of anticholinergic treatment.
Topics: Adolescent; Blood Glucose; Cholinergic Antagonists; Diabetes Mellitus, Type 1; Female; Glycated Hemo | 2002 |
Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose; Gluc | 2004 |
Effects of recombinant human IGF-I/IGF-binding protein-3 complex on glucose and glycerol metabolism in type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type | 2006 |
Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study.
Topics: Adolescent; Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Double-Blind | 2008 |
Microdialysis technique as a monitoring system for acute complications of diabetes.
Topics: Abdominal Fat; Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 2008 |
Metabolic and circulatory effects of oral salbutamol in the third trimester of pregnancy in diabetic and non-diabetic women.
Topics: Adult; Albuterol; Blood Glucose; C-Peptide; Cyclic AMP; Diabetes Mellitus, Type 1; Fatty Acids, None | 1981 |
The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues.
Topics: Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Gluconeogenesis; Glucose; Gluc | 1995 |
Effects of hyperglycemia on in vivo adipose tissue metabolism studied with microdialysis in IDDM subjects.
Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucose Clamp Technique; Gl | 1994 |
Clinical evaluation of a semipermeable polymeric membrane dressing for the treatment of chronic diabetic foot ulcers.
Topics: Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Foot; Female; Glycer | 1994 |
Characterization of the insulin-antagonistic effect of growth hormone in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucose Clamp T | 1995 |
Exercise-induced changes in neuropeptide Y, noradrenaline and endothelin-1 levels in young people with type I diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Endothelin-1; Energy Metabolism; Exercise; Exercise | 1996 |
Ketosis resistance in fibrocalculous pancreatic diabetes: II. Hepatic ketogenesis after oral medium-chain triglycerides.
Topics: Adipose Tissue; Administration, Oral; Adult; Blood Glucose; C-Peptide; Carnitine; Diabetes Complicat | 1997 |
Metabolic efficacy of preprandial administration of Lys(B28), Pro(B29) human insulin analog in IDDM patients. A comparison with human regular insulin during a three-meal test period.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Blood Glucose; Child; Cross-Over Studies; Diabetes Mellitu | 1997 |
Abnormal glucose handling by the kidney in response to hypoglycemia in type 1 diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Female; Glucose; Glycerol | 2001 |
Metabolic effects of aldose reductase inhibition in diabetic man.
Topics: Alanine; Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Di | 1992 |
Glycerol-insulin raises circulating insulin antibodies in type I diabetic patients treated with permanently implanted devices.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Combinations; Drug Stability; Female; Glycerol | 1988 |
Human ultralente insulin: a comparison with porcine lente insulin as a twice-daily insulin in insulin-dependent diabetic patients with fasting hyperglycaemia.
Topics: 3-Hydroxybutyric Acid; Adult; Animals; Blood Glucose; Circadian Rhythm; Clinical Trials as Topic; Di | 1986 |
Diurnal plasma profiles of metabolite and hormone concentration in insulin-dependent diabetic patients during conventional insulin treatment and continuous subcutaneous insulin infusion. A controlled study.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Gl | 1987 |
98 other studies available for glycerol and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis.
Topics: Adipose Tissue; Adult; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus | 2013 |
Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus, Exper | 2016 |
Modeling changes in glucose and glycerol rates of appearance when true basal rates of appearance cannot be readily determined.
Topics: Adolescent; Algorithms; Blood Glucose; Case-Control Studies; Child; Deuterium; Diabetes Mellitus, Ty | 2016 |
Interstitial measurements of glucose, glycerol and lactate in adolescents with decompensated type 1 diabetes.
Topics: Adipose Tissue; Adolescent; Diabetes Mellitus, Type 1; Female; Glucose; Glycerol; Humans; Lactic Aci | 2010 |
Analyte flux at a biomaterial-tissue interface over time: implications for sensors for type 1 and 2 diabetes mellitus.
Topics: Adult; Aged; Biocompatible Materials; Biopsy; Biosensing Techniques; Diabetes Mellitus, Type 1; Diab | 2010 |
Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: The CACTI study.
Topics: Abdomen; Absorptiometry, Photon; Adipose Tissue; Adult; Blood Glucose; Body Composition; Calcium; Co | 2011 |
Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: The CACTI study.
Topics: Abdomen; Absorptiometry, Photon; Adipose Tissue; Adult; Blood Glucose; Body Composition; Calcium; Co | 2011 |
Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: The CACTI study.
Topics: Abdomen; Absorptiometry, Photon; Adipose Tissue; Adult; Blood Glucose; Body Composition; Calcium; Co | 2011 |
Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: The CACTI study.
Topics: Abdomen; Absorptiometry, Photon; Adipose Tissue; Adult; Blood Glucose; Body Composition; Calcium; Co | 2011 |
Polyethylene glycolated recombinant TNF receptor I improves insulitis and reduces incidence of spontaneous and cyclophosphamide-accelerated diabetes in nonobese diabetic mice.
Topics: Animals; Autoimmune Diseases; Corticosterone; Cyclophosphamide; Diabetes Mellitus, Type 1; Fatty Aci | 2002 |
Effect of gender on counterregulatory responses to euglycemic exercise in type 1 diabetes.
Topics: Adult; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Fatty | 2002 |
Reduction of plasma leptin concentrations by arginine but not lipid infusion in humans.
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fat Emulsions, Int | 2002 |
Defective activation of skeletal muscle and adipose tissue lipolysis in type 1 diabetes mellitus during hypoglycemia.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephri | 2003 |
In situ evidence that peripheral insulin resistance in adolescents with poorly controlled type 1 diabetes is associated with impaired suppression of lipolysis: a microdialysis study.
Topics: Adipose Tissue; Adolescent; Diabetes Mellitus, Type 1; Fats; Female; Glucose; Glucose Clamp Techniqu | 2003 |
In situ evidence that peripheral insulin resistance in adolescents with poorly controlled type 1 diabetes is associated with impaired suppression of lipolysis: a microdialysis study.
Topics: Adipose Tissue; Adolescent; Diabetes Mellitus, Type 1; Fats; Female; Glucose; Glucose Clamp Techniqu | 2003 |
In situ evidence that peripheral insulin resistance in adolescents with poorly controlled type 1 diabetes is associated with impaired suppression of lipolysis: a microdialysis study.
Topics: Adipose Tissue; Adolescent; Diabetes Mellitus, Type 1; Fats; Female; Glucose; Glucose Clamp Techniqu | 2003 |
In situ evidence that peripheral insulin resistance in adolescents with poorly controlled type 1 diabetes is associated with impaired suppression of lipolysis: a microdialysis study.
Topics: Adipose Tissue; Adolescent; Diabetes Mellitus, Type 1; Fats; Female; Glucose; Glucose Clamp Techniqu | 2003 |
The role of intramyocellular lipids during hypoglycemia in patients with intensively treated type 1 diabetes.
Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesteri | 2005 |
Subcutaneous microdialysis before and after an oral glucose tolerance test: a method to determine insulin resistance in the subcutaneous adipose tissue in diabetes mellitus.
Topics: Adult; Anthropometry; Blood Glucose; Body Mass Index; Diabetes Mellitus; Diabetes Mellitus, Type 1; | 2005 |
Antecedent hypoglycemia does not alter increased epinephrine-induced lipolysis in type 1 diabetes mellitus.
Topics: Adolescent; Adult; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids; Female; Glucose; Glucose Cla | 2006 |
Dietary fats, the diurnal blood lipids and ketones in juvenile diabetes.
Topics: Adolescent; Adult; Child; Cholesterol; Circadian Rhythm; Diabetes Mellitus, Type 1; Diet Therapy; Di | 1966 |
Studies on fatty acid metabolism in diabetics during exercise. VI. Infusions of norepinephrine to male, non-insulin-treated, juvenile diabetics.
Topics: Adipose Tissue; Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterif | 1967 |
Adrenergic blockade and hypoglycaemia.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Glucag | 1983 |
Tolbutamide does not alter insulin requirement in Type 1 (insulin-dependent) diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Fatty Acids, Nonesterified; Glucagon; G | 1984 |
Clinical experience with insulin-glycerol solution in an implantable pump.
Topics: Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Glycerol; | 1983 |
Metabolic effects of physical exercise in insulin-dependent diabetics controlled by continuous subcutaneous insulin infusion or conventional injection therapy.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Energy Metabolism; Fatty Acids, Nonesterif | 1984 |
Metabolic effects of intensified insulin therapy.
Topics: Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Schedule; Fatty Acids, Nonest | 1984 |
Short-term of the artificial beta-cell (Biostator) on pancreatic glucagon response in insulin-dependent diabetic (IDDM).
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose; Glyc | 1984 |
The effect of exogenous growth hormone on insulin requirements during closed loop insulin delivery in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Food; Glycerol; Growth Hormone; | 1984 |
Biochemical determination of training effects using insulin clamp technique.
Topics: Adolescent; Adult; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterif | 1984 |
The response of blood intermediary metabolite levels to 24 hours treatment with a blood glucose-controlled insulin infusion system in type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glycerol; H | 1984 |
Effects of acetylsalicylic acid on blood glucose, plasma FFA, glycerol, 3-hydroxybutyrate, alanine, C-peptide, glucagon and growth hormone responses to arginine in insulin-dependent diabetics.
Topics: Adolescent; Adult; Alanine; Arginine; Aspirin; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; | 1980 |
Blood glucose control and lipolysis in diabetes mellitus.
Topics: Adipose Tissue; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glycerol; Humans; Insul | 1980 |
Hormonal, metabolic, and cardiovascular responses to hypoglycemia in diabetic autonomic neuropathy.
Topics: Adult; Autonomic Nervous System Diseases; Blood Pressure; Body Temperature; Diabetes Mellitus, Type | 1981 |
Impaired responses of catecholamines, growth hormone, and cortisol to graded exercise in diabetic autonomic neuropathy.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Epinephrine; Fatty Acids, No | 1980 |
Lipid and carbohydrate metabolism in IDDM during moderate and intense exercise.
Topics: Adult; Blood Glucose; Calorimetry; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Exercise; Fat | 1995 |
Hormonal, metabolic, and circulatory responses to insulin-induced hypoglycemia in pregnant and nonpregnant women with insulin-dependent diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Circulation; Blood Glucose; Blood Pressure; Catecholamines; Diab | 1994 |
Insulin receptor down-regulation and impaired antilipolytic action of insulin in diabetic patients after pancreas/kidney transplantation.
Topics: Adult; Diabetes Mellitus, Type 1; Down-Regulation; Esterification; Fatty Acids; Female; Glucose Clam | 1994 |
Intensive insulin therapy and weight gain in IDDM.
Topics: Adipose Tissue; Adult; Basal Metabolism; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; | 1993 |
Hepatic glucose production during intraperitoneal and intravenous closed-loop insulin regulation of blood glucose in type 1 (insulin-dependent) diabetic patients.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, None | 1993 |
Post-hypoglycaemic hyperketonaemia does not contribute to brain metabolism during insulin-induced hypoglycaemia in humans.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Brain; Cognition; Diabetes Mellitus, Type 1; Female; Glycerol | 1993 |
Effects of different plasma glucose concentrations on lipolytic and ketogenic responsiveness to epinephrine in type I (insulin-dependent) diabetic subjects.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; | 1993 |
Short-term fasting is a mechanism for the development of euglycemic ketoacidosis during periods of insulin deficiency.
Topics: Adult; Bicarbonates; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fasting; Fatty | 1993 |
Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Adm | 1995 |
Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Fatty | 1996 |
Stimulation of adipose tissue lipolysis following insulin-induced hypoglycaemia: evidence of increased beta-adrenoceptor-mediated lipolytic response in IDDM.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Analysis of Varian | 1996 |
Effects of the short-acting insulin analog [Lys(B28),Pro(B29)] on postprandial blood glucose control in IDDM.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mell | 1996 |
Cardiovascular, metabolic, and hormonal responses to noradrenaline in diabetic patients with autonomic neuropathy.
Topics: 3-Hydroxybutyric Acid; Adrenergic alpha-Agonists; Adult; Blood Glucose; Blood Pressure; Cardiac Outp | 1996 |
A circadian rhythm in lipid mobilization which is altered in IDDM.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Blood Glucose; Circadian Rhythm; Diabetes Mellitus | 1997 |
Microdialysis for the assessment of catecholamine-induced lipolysis in adipose and skeletal muscle tissue.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Catecholamines; Diabetes Mell | 1998 |
Lipolytic response during spontaneous hypoglycaemia in insulin-dependent diabetic subjects.
Topics: Adipose Tissue; Adult; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Fatt | 1998 |
Glucoregulation during and after intense exercise: effects of beta-adrenergic blockade in subjects with type 1 diabetes mellitus.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrin | 1999 |
Low-dose IGF-I has no selective advantage over insulin in regulating glucose metabolism in hyperglycemic depancreatized dogs.
Topics: 3-Hydroxybutyric Acid; Alanine; Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Typ | 2001 |
Effect of metaproterenol on ketone body metabolism of the forearm in healthy and diabetic subjects.
Topics: Acetoacetates; Adult; Diabetes Mellitus, Type 1; Forearm; Glycerol; Humans; Hydroxybutyrates; Ketone | 1979 |
Training adaptations in skeletal muscle of juvenile diabetics.
Topics: Adult; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; | 1979 |
Normalisation of growth hormone hypersecretion in uraemic diabetics and non-diabetics. Studies with artificial pancreas and artificial kidney.
Topics: Alanine; Artificial Organs; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Fe | 1979 |
[Studies on the influence of dietary regimens rich in fats and carbohydrates, on the fatty and carbohydrate metabolism of children suffering from diabetes mellitus (author's transl)].
Topics: Adolescent; Bicarbonates; Blood Glucose; Child; Cholesterol; Diabetes Mellitus, Type 1; Dietary Carb | 1978 |
[Stimulation test for carbohydrate metabolism in childhood. "Normal values" of oral glucose tolerance test using 1,75g/kg from venous and capillary blood].
Topics: Adolescent; Blood Glucose; Capillaries; Carbohydrate Metabolism; Child; Diabetes Mellitus, Type 1; F | 1977 |
Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon.
Topics: Adult; Alanine; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Type 1; Diabetic Ketoacidosi | 1975 |
Plasma glucagon and alanine responses to acute insulin deficiency in man.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glyc | 1975 |
The ketosis-resistance in fibro-calculous-pancreatic-diabetes. 1. Clinical observations and endocrine-metabolic measurements during oral glucose tolerance test.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Cholesterol; Diabetes Mellitus; Diabetes Mel | 1992 |
Role of GH in regulating nocturnal rates of lipolysis and plasma mevalonate levels in normal and diabetic humans.
Topics: Adult; Catecholamines; Cholesterol; Circadian Rhythm; Diabetes Mellitus, Type 1; Fatty Acids, Nonest | 1992 |
Normalization of hepatic glucose regulation despite systemic insulin delivery. Studies in patients with pancreatic transplantation for type 1 (insulin-dependent) diabetes mellitus.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucose; Glyce | 1991 |
Decreased hepatic glucagon responses in type 1 (insulin-dependent) diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Fatty Ac | 1991 |
Do enzymatic analyses of serum triglycerides really need blanking for free glycerol?
Topics: Adipose Tissue; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glycerol; Humans; Triglyceride | 1991 |
Glucose counterregulation in diabetes secondary to chronic pancreatitis.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Blood Pressure; Diabetes Mellitus; Diabetes Mellitus, Ty | 1990 |
The short-term effect of nicotinic acid on intermediary metabolism in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Humans; Insul | 1991 |
Physiological effects of mental stress and orthostasis in young insulin-dependent diabetic patients.
Topics: Adolescent; Adult; Analysis of Variance; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; E | 1991 |
Effects of insulin deprivation and replacement on in vivo subcutaneous adipose tissue substrate metabolism in humans.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Dialysis; Ep | 1991 |
Insulin resistance in type 1 (insulin-dependent) diabetes: dissimilarities for glucose and intermediary metabolites.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterif | 1990 |
Effect of phase of menstrual cycle on insulin sensitivity, peripheral blood flow and cardiovascular responses to hyperinsulinaemia in young women with type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Female; Fore | 1990 |
Increased lipolytic sensitivity to catecholamines in diabetic patients with severe autonomic neuropathy.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Adult; Autonomic Nervous System Diseases; Blood Glucose; Cate | 1990 |
Substrate metabolism during modest hyperinsulinemia in response to isolated hyperketonemia in insulin-dependent diabetic subjects.
Topics: 3-Hydroxybutyric Acid; Adult; Diabetes Mellitus, Type 1; Gluconeogenesis; Glucose; Glycerol; Hormone | 1990 |
The relationship of plasma acetate with glucose and other blood intermediary metabolites in non-diabetic and diabetic subjects.
Topics: Acetates; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Fatty | 1989 |
The effects of SMS 201-995 (sandostatin) on metabolic profiles in insulin-dependent diabetes mellitus.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glycerol; Growth Hormone | 1989 |
[Role of insulin and counter-regulatory hormones in the metabolic changes caused by insulin deprivation in diabetic patients].
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Glucagon; Glyce | 1989 |
Sandostatin, a new analogue of somatostatin, reduces the metabolic changes induced by the nocturnal interruption of continuous subcutaneous insulin infusion in type 1 (insulin-dependent) diabetic patients.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Neuropat | 1989 |
Carbohydrate, lipid and amino acid metabolism of insulin-dependent diabetic patients regulated by an artificial beta-cell unit.
Topics: Adult; Amino Acids; Blood Glucose; Carbohydrates; Diabetes Mellitus, Type 1; Drug Administration Sch | 1989 |
Lack of beta-adrenergic role for catecholamines in the development of hyperglycemia and ketonaemia following acute insulin withdrawal in type I diabetic patients.
Topics: Adult; Catecholamines; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids, Nonesterified; Glucagon; | 1985 |
Intermediary metabolism and glycemic control in insulin-dependent diabetic uremic patients treated by continuous peritoneal dialysis.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glycerol; Humans; Insulin; Lactates; Male; | 1988 |
Glucagon, not insulin, may play a secondary role in defense against hypoglycemia during exercise.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Epi | 1988 |
Metabolic effects of low-dose incremental insulin infusion in diabetic man.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Huma | 1986 |
Metabolic rhythms in adolescents with diabetes during treatment with porcine or human insulin.
Topics: Adolescent; Animals; Blood Glucose; Child; Diabetes Mellitus, Type 1; Drug Administration Schedule; | 1986 |
Overnight metabolic profiles in very young insulin-dependent diabetic children.
Topics: Age Factors; Alanine; Blood Glucose; Child; Child, Preschool; Delayed-Action Preparations; Diabetes | 1986 |
Treatment with artificial beta-cell decreases very-low-density lipoprotein triglyceride synthesis in type I diabetes.
Topics: Adult; Aged; Biological Transport; Blood Glucose; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, | 1987 |
Multiple aspects of insulin resistance. Comparison of glucose and intermediary metabolite response to incremental insulin infusion in IDDM subjects of short and long duration.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucose; Glyce | 1987 |
Determination of steady state and nonsteady-state glycerol kinetics in humans using deuterium-labeled tracer.
Topics: Adult; Animals; Deuterium; Diabetes Mellitus, Type 1; Female; Gas Chromatography-Mass Spectrometry; | 1987 |
Muscular exercise in type I-diabetics. II. Hormonal and metabolic responses to moderate exercise.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucago | 1985 |
Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine
Topics: Adult; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 1; Epinephrine; Fatty Acids | 1985 |
Evidence for a substrate regulation of triglyceride lipolysis in human skeletal muscle.
Topics: Adult; Diabetes Mellitus, Type 1; Fructose; Glucose; Glycerol; Humans; Insulin; Lipid Mobilization; | 1985 |
The metabolic response to the euglycemic insulin clamp in type I diabetes and normal humans.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fasting; Fatty Acid | 1985 |
Free insulin levels and metabolic effects of meal-time bolus and square-wave intraperitoneal insulin infusion in insulin-dependent diabetic patients.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonest | 1985 |
Metabolic rhythms in adolescents with diabetes.
Topics: Activity Cycles; Adolescent; Blood Glucose; Child; Circadian Rhythm; Diabetes Mellitus, Type 1; Fema | 1986 |
Plasma-levels of glucose, non-esterified fatty acid, glycerol, and insulin four years before the onset of diabetic ketosis.
Topics: Blood Glucose; Child; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Fatty Acids; Fatty Acids, No | 1967 |
The effect of insulin in vitro on human adipose tissue from normal and diabetic subjects.
Topics: Abdominal Muscles; Acetoacetates; Adipose Tissue; Adult; Aged; Blood Glucose; Carbon Isotopes; Diabe | 1967 |
Adipose tissue cellularity and metabolism in newly diagnosed juvenile diabetics.
Topics: Adenylyl Cyclases; Adipose Tissue; Adolescent; Body Height; Body Weight; Carbon Dioxide; Child; Chil | 1973 |
[The effect of the lipolysis blocker 5-methylpyrazol-3-carbonic acid (MPC) on changes in carbohydrate and lipid metabolism induced by muscle work in insulin-requiring diabetics].
Topics: Acetone; Adult; Blood Glucose; Carboxylic Acids; Diabetes Mellitus, Type 1; Dietary Carbohydrates; D | 1973 |
[Effects of the intravenous infusion of nicotinic acid on blood concentrations of substrates, metabolites and hormones in juvenile-onset diabetes].
Topics: 17-Hydroxycorticosteroids; Animals; Blood Glucose; Carbon Isotopes; Catecholamines; Diabetes Mellitu | 1970 |
Studies on fatty acid metabolism in diabetics during exercise. VII. Plasma glycerol concentrations in juvenile diabetics during exercise before and after adequate insulin treatment.
Topics: Adipose Tissue; Adult; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1; Fatty A | 1969 |
[Muscle work and diabetes mellitus. II. Influence of subliminal insulin doses on the carbohydrate and lipid metabolism under acute work-load].
Topics: Acetone; Adult; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Fasting; Fatty Ac | 1970 |
Ketone body, free fatty acid, and glucose concentrations in 'maturity' and 'juvenile' diabetics after insulin.
Topics: Acetoacetates; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterifi | 1971 |
Metabolism of glycerol in diabetes mellitus.
Topics: Blood Glucose; Cholesterol; Computers; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatty Acids, No | 1967 |
[Stimulation of insulin secretion in diabetics using secretin].
Topics: Adolescent; Adult; Age Factors; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; F | 1968 |
Effects of glucose infusions on adipose tissue lipogenesis in man.
Topics: Acetates; Adipose Tissue; Biopsy; Carbon Dioxide; Carbon Isotopes; Citrates; Culture Techniques; Dia | 1968 |