glycerol has been researched along with Chondromalacia in 6 studies
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.
Chondromalacia: Softening and degeneration of the CARTILAGE.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (66.67) | 29.6817 |
2010's | 2 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Jing, B | 1 |
Wang, Z | 1 |
Li, B | 1 |
Cheng, Z | 1 |
Kang, Y | 1 |
Li, Q | 1 |
Hoemann, CD | 5 |
Chen, G | 1 |
Marchand, C | 1 |
Tran-Khanh, N | 1 |
Thibault, M | 1 |
Chevrier, A | 5 |
Sun, J | 5 |
Shive, MS | 2 |
Fernandes, MJ | 1 |
Poubelle, PE | 1 |
Centola, M | 1 |
El-Gabalawy, H | 1 |
Buschmann, MD | 4 |
Hurtig, M | 2 |
Rossomacha, E | 2 |
McKee, MD | 1 |
Rivard, GE | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Randomized, Comparative Multicenter Clinical Trial Evaluating BST-CarGel™ and Microfracture in Repair of Focal Articular Cartilage Lesions on the Femoral Condyle[NCT00314236] | 80 participants (Actual) | Interventional | 2005-12-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Evaluate the efficacy of BST-CarGel® applied to a microfractured lesion as compared to microfracture alone on the degree of lesion filling of the study knee in subjects with symptomatic pain associated with cartilage damage using MRI scans. The MR images will be acquired using high resolution 3D cartilage imaging sequences, so-called cartilage morphology sequences. (NCT00314236)
Timeframe: 12 months
Intervention | Percentage of lesion fill (Least Squares Mean) |
---|---|
Experimental | 92.81 |
Control | 85.22 |
(NCT00314236)
Timeframe: 12 months
Intervention | Percentage of participants (Number) |
---|---|
Experimental | 97.6 |
Control | 92.3 |
Evaluate the efficacy of BST-CarGel® applied to a microfractured lesion as compared to microfracture alone on the repair tissue quality of the study knee in subjects with symptomatic pain associated with cartilage damage using MRI T2 mapping. T2 maps are created by calculating the T2 relaxation times for repair tissue and cartilage plates for every voxel (picture element of a MRI scan containing the average signal information of a specific spatial location of the imaged body). (NCT00314236)
Timeframe: 12 months
Intervention | milliseconds (Least Squares Mean) |
---|---|
Experimental | 70.46 |
Control | 85.04 |
The three sub-scales: 1) Pain, 2.) stiffness and 3.) function scores ranged from 0-10. Pain had 5 items and stiffness had 2 items, and function had 17 items. The total score for pain ranged from 0 no pain to 50 worst pain. The total score for stiffness ranged from 0 no stiffness to 20 worst stiffness. The total score for function raged from 0 no function to 170 worst function. (NCT00314236)
Timeframe: 12 months
Intervention | Units on a scale (Least Squares Mean) | ||
---|---|---|---|
Pain | Stiffness | Function | |
Control | -16.91 | -6.56 | -60.59 |
Experimental | -16.16 | -5.97 | -55.96 |
6 other studies available for glycerol and Chondromalacia
Article | Year |
---|---|
[A preliminary study of high viscous chitosan/glycerol phosphate with demineralized bone matrix to repair cartilage defects in rabbits].
Topics: Animals; Biocompatible Materials; Bone Demineralization Technique; Bone Matrix; Cartilage; Cartilage | 2008 |
Scaffold-guided subchondral bone repair: implication of neutrophils and alternatively activated arginase-1+ macrophages.
Topics: Adult; Angiogenesis Inducing Agents; Animals; Arginase; Arthroplasty, Subchondral; Blood Coagulation | 2010 |
Temporal and spatial modulation of chondrogenic foci in subchondral microdrill holes by chitosan-glycerol phosphate/blood implants.
Topics: Animals; Biomarkers; Cartilage Diseases; Cell Proliferation; Chitosan; Chondrogenesis; Coagulants; C | 2011 |
Chitosan-glycerol phosphate/blood implants improve hyaline cartilage repair in ovine microfracture defects.
Topics: Animals; Blood Coagulation; Cartilage Diseases; Chitosan; Coagulants; Glycerol; Hyalin; Models, Anim | 2005 |
Chitosan-glycerol phosphate/blood implants elicit hyaline cartilage repair integrated with porous subchondral bone in microdrilled rabbit defects.
Topics: Animals; Blood Coagulation; Cartilage Diseases; Chitosan; Coagulants; Collagen Type II; Glycerol; Hy | 2007 |
Chitosan-glycerol phosphate/blood implants increase cell recruitment, transient vascularization and subchondral bone remodeling in drilled cartilage defects.
Topics: Animals; Blood Coagulation; Cartilage Diseases; Chitosan; Chondrogenesis; Coagulants; Glycerol; Hyal | 2007 |