Page last updated: 2024-10-18

glycerol and Brain Ischemia

glycerol has been researched along with Brain Ischemia in 63 studies

Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"This systematic review suggests a favourable effect of glycerol treatment on short term survival in patients with probable or definite ischaemic stroke but the confidence intervals were wide and the magnitude of the treatment effect may be only minimal."8.82Glycerol for acute stroke. ( Boysen, G; Cantisani, T; Celani, MG; Ricci, S; Righetti, E; Sterzi, R, 2004)
"There is not enough evidence to evaluate glycerol treatment for people with acute ischaemic stroke."8.80Glycerol for acute ischaemic stroke. ( a'Rogvi-Hansen, B; Boysen, G, 2000)
"This systematic review suggests a favourable effect of glycerol treatment on short term survival in patients with probable or definite ischaemic stroke but the magnitude of the treatment effect may be minimal (as low as a 3% reduction in odds)."8.80Glycerol for acute stroke. ( Boysen, G; Cantisani, T; Celani, MG; Ricci, S; Righetti, E; Sterzi, R, 2000)
"We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model."7.73Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005)
"We here reported the clinical course and therapeutic details of a 16-year-old girl with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had had five stroke-like episodes (two episodes were clinically mild, while the three subsequent episodes were severe)."7.72Beneficial effect of L-arginine for stroke-like episode in MELAS. ( Kubota, M; Momoi-Yoshida, M; Mori, M; Sakakihara, Y; Yamagata, T, 2004)
"A PGI2 derivative, OP-41483, and a hyperosmotic agent, glycerol, were tested for possible beneficial effects on brain edema, metabolism and pathological changes in cerebral ischemia."7.68Effect of a prostacyclin derivative (OP-41483) and a hyperosmotic agent (glycerol) on brain edema and metabolism in cerebral ischemia. ( Kashiwagi, F; Katayama, Y; Memezawa, H; Terashi, A, 1992)
"Using two different models of non ischemic and transient cerebral ischemia in SHR, the effect of hyperosmolar solution with intravenous 10% glycerol on serum lipid peroxides, plasma prostaglandins (TXA2, PGI2), brain water content and brain metabolites were studied."7.67[Effect of glycerol administration on experimental cerebral ischemia--Part 1. Studies on lipid peroxides, prostaglandins, brain edema and brain metabolites]. ( Kashiwagi, F; Katayama, Y; Nagazumi, A; Shimizu, J; Suzuki, S; Terashi, A, 1988)
"The effects of antiedematous agent with intravenous 10% glycerol on cerebral blood flow (CBF) and metabolism were studied in acute cerebral ischemia experimentally induced by bilateral carotid artery occlusion in spontaneously hypertensive rats (SHR)."7.67Effects of intravenous glycerol on cerebral blood flow and tissue metabolism in acute cerebral ischemia in spontaneously hypertensive rats. ( Fujishima, M; Ibayashi, S; Ishitsuka, T; Sadoshima, S; Shiokawa, O; Yoshida, F, 1986)
"The aim of this study is to assess the anticerebral edema effect of glycerol on a large cerebral infarction with magnetic resonance imaging (MRI)."5.10Effect of glycerol on ischemic cerebral edema assessed by magnetic resonance imaging. ( Ando, J; Chishiki, T; Curran, BC; Hagiwara, H; Igarashi, H; Katayama, Y; Nishiyama, Y; Sakamaki, M, 2003)
" The authors' goal was to characterize patterns of markers of energy metabolism (glucose, pyruvate, and lactate) and neuronal injury (glutamate and glycerol) in patients with subarachnoid hemorrhage (SAH), in whom ischemia was or was not suspected."5.09Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage. ( Bjerre, P; Schulz, MK; Tange, M; Wang, LP, 2000)
"This systematic review suggests a favourable effect of glycerol treatment on short term survival in patients with probable or definite ischaemic stroke but the confidence intervals were wide and the magnitude of the treatment effect may be only minimal."4.82Glycerol for acute stroke. ( Boysen, G; Cantisani, T; Celani, MG; Ricci, S; Righetti, E; Sterzi, R, 2004)
"There is not enough evidence to evaluate glycerol treatment for people with acute ischaemic stroke."4.80Glycerol for acute ischaemic stroke. ( a'Rogvi-Hansen, B; Boysen, G, 2000)
"This systematic review suggests a favourable effect of glycerol treatment on short term survival in patients with probable or definite ischaemic stroke but the magnitude of the treatment effect may be minimal (as low as a 3% reduction in odds)."4.80Glycerol for acute stroke. ( Boysen, G; Cantisani, T; Celani, MG; Ricci, S; Righetti, E; Sterzi, R, 2000)
"We assess the effects of ipsapirone (a 5-HT1A receptor agonist), ketanserin (a 5-HT2A receptor antagonist), (-)-pindolol (a 5-HT1A receptor antagonist), and DOI (a 5-HT2A receptor agonist) on heatstroke in a rat model."3.73Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke. ( Chang, CP; Chen, SH; Lin, MT, 2005)
"We here reported the clinical course and therapeutic details of a 16-year-old girl with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had had five stroke-like episodes (two episodes were clinically mild, while the three subsequent episodes were severe)."3.72Beneficial effect of L-arginine for stroke-like episode in MELAS. ( Kubota, M; Momoi-Yoshida, M; Mori, M; Sakakihara, Y; Yamagata, T, 2004)
"Bedside intracerebral microdialysis monitoring of patients with subarachnoid hemorrhage and signs of delayed ischemia revealed dramatic changes in extracellular concentrations of glucose, lactate, and glycerol that could be directly correlated to the clinical status of the patients."3.70Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration. ( Brandt, L; Nilsson, OG; Säveland, H; Ungerstedt, U, 1999)
"A PGI2 derivative, OP-41483, and a hyperosmotic agent, glycerol, were tested for possible beneficial effects on brain edema, metabolism and pathological changes in cerebral ischemia."3.68Effect of a prostacyclin derivative (OP-41483) and a hyperosmotic agent (glycerol) on brain edema and metabolism in cerebral ischemia. ( Kashiwagi, F; Katayama, Y; Memezawa, H; Terashi, A, 1992)
"Using two different models of non ischemic and transient cerebral ischemia in SHR, the effect of hyperosmolar solution with intravenous 10% glycerol on serum lipid peroxides, plasma prostaglandins (TXA2, PGI2), brain water content and brain metabolites were studied."3.67[Effect of glycerol administration on experimental cerebral ischemia--Part 1. Studies on lipid peroxides, prostaglandins, brain edema and brain metabolites]. ( Kashiwagi, F; Katayama, Y; Nagazumi, A; Shimizu, J; Suzuki, S; Terashi, A, 1988)
"The effects of antiedematous agent with intravenous 10% glycerol on cerebral blood flow (CBF) and metabolism were studied in acute cerebral ischemia experimentally induced by bilateral carotid artery occlusion in spontaneously hypertensive rats (SHR)."3.67Effects of intravenous glycerol on cerebral blood flow and tissue metabolism in acute cerebral ischemia in spontaneously hypertensive rats. ( Fujishima, M; Ibayashi, S; Ishitsuka, T; Sadoshima, S; Shiokawa, O; Yoshida, F, 1986)
"With corticosteroids and diuretics, glycerol treatment may be an effective therapy of early edema accompanying focal brain ischemia."3.66Therapy of ischemic brain edema. ( Battistini, N, 1978)
"Thirteen subarachnoid hemorrhage patients (age, 48."2.71Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study. ( Amthauer, H; Haux, D; Küchler, I; Lüdemann, L; Plotkin, M; Sarrafzadeh, AS; Unterberg, AW, 2004)
"Glycerol is an integral component of cell membranes."2.46[Use of intracerebral microdialysis in severe traumatic brain injury]. ( Abe, Y; Kawai, N; Kawakita, K; Kuroda, Y; Tamiya, T; Yano, T, 2010)
"Ischemic brain edema promotes focal cerebral ischemia by increasing intracranial pressure and thereby reducing perfusion pressure, obstructing capillaries and prolonging transport routes within ischemic tissue."2.39[Treatment of ischemic cerebral infarct with glycerine]. ( Hacke, W; Nau, R; Winter, R, 1995)
"Stroke is a major cause of death and disability in China, and no therapies have proven effective to prevent it."1.56Sex differences in the effects of the moon on ischemic stroke incidence: new findings from Beijing, China. ( Chen, J; Hao, Y; He, J; Shi, LS; Wang, MQ; Wang, RR; Zheng, RY, 2020)
"Aneurysmal subarachnoid hemorrhage (SAH) is frequently associated with delayed neurological deterioration (DND)."1.40Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage. ( Jacobsen, A; Nielsen, TH; Nilsson, O; Nordström, CH; Schalén, W, 2014)
"When biochemical signs of cerebral ischemia progressed, i."1.37Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue. ( Nordström, CH; Reinstrup, P, 2011)
"Heatstroke was induced by exposing the anesthetized rats to a high ambient temperature (Ta = 43 degrees C) until the moment at which MAP decreased from its peak level."1.33Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion. ( Ke, DS; Lin, MT; Wang, JL, 2005)
"In the treatment of patients with aneurysmal subarachnoid hemorrhage (SAH), early occlusion of the aneurysm is necessary as well as monitoring and treatment of complications following the primary bleeding episode."1.32Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage. ( Bjerre, P; Kristensen, SR; Schulz, M; Skjøth-Rasmussen, J, 2004)
"Glycerol was measured in microdialysis samples from the frontal lobe cortex in four patients in the neurointensive care unit, during the acute phase after severe aneurysmal subarachnoid haemorrhage."1.30Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain. ( Enblad, P; Hillered, L; Persson, L; Valtysson, J, 1998)
"Forebrain ischemia was induced by clipping of bilateral common carotid arteries for 90 min and reperfused."1.30Effects of mannitol and glycerol on cerebral energy metabolism in gerbils. ( Hatanaka, Y; Izumi, Y; Kitadai, M; Tsuda, Y, 1998)
"Cerebral ischemia was induced by bilateral common carotid artery ligation (BLCL) using spontaneously hypertensive rats (SHR)."1.28Effect of a new hyperosmotic agent, NIK-242 injection, on brain water content, metabolites and cerebral blood flow in cerebral ischemia in the spontaneously hypertensive rat. ( Kamiya, T; Kashiwagi, F; Katayama, Y; Shimizu, J; Terashi, A, 1991)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199015 (23.81)18.7374
1990's13 (20.63)18.2507
2000's27 (42.86)29.6817
2010's5 (7.94)24.3611
2020's3 (4.76)2.80

Authors

AuthorsStudies
Lee, J2
Shin, JA2
Lee, EM2
Nam, M2
Park, EM2
Kofler, M1
Gaasch, M1
Rass, V1
Schiefecker, AJ1
Ianosi, B1
Lindner, A1
Beer, R1
Stover, JF1
Rhomberg, P1
Pfausler, B1
Thomé, C1
Schmutzhard, E1
Helbok, R1
Jacobsen, A1
Nielsen, TH1
Nilsson, O1
Schalén, W1
Nordström, CH4
Tovedal, T1
Jonsson, O1
Zemgulis, V1
Myrdal, G1
Thelin, S1
Lennmyr, F1
Kawai, N1
Kawakita, K1
Yano, T1
Abe, Y1
Kuroda, Y1
Tamiya, T1
Sumbria, RK1
Klein, J1
Bickel, U1
Reinstrup, P1
Schäbitz, WR2
Giuffrida, A1
Berger, C2
Aschoff, A2
Schwaninger, M1
Schwab, S2
Piomelli, D1
Romsi, P1
Kaakinen, T1
Kiviluoma, K1
Vainionpää, V1
Hirvonen, J1
Pokela, M1
Ohtonen, P1
Biancari, F1
Nuutinen, M1
Juvonen, T1
Sakamaki, M1
Igarashi, H1
Nishiyama, Y1
Hagiwara, H1
Ando, J1
Chishiki, T1
Curran, BC1
Katayama, Y6
Chou, YT1
Lai, ST1
Lee, CC1
Lin, MT4
Chang, CK1
Chiu, WT1
Chang, CP2
Skjøth-Rasmussen, J1
Schulz, M1
Kristensen, SR1
Bjerre, P2
Sarrafzadeh, AS2
Haux, D1
Lüdemann, L1
Amthauer, H1
Plotkin, M1
Küchler, I1
Unterberg, AW2
Righetti, E2
Celani, MG2
Cantisani, T2
Sterzi, R2
Boysen, G3
Ricci, S2
Kubota, M1
Sakakihara, Y1
Mori, M1
Yamagata, T1
Momoi-Yoshida, M1
Wang, JL1
Ke, DS1
Chen, SH1
Poca, MA1
Sahuquillo, J1
Mena, MP1
Vilalta, A1
Riveiro, M1
Nguyen, NH1
Gonzalez, SV1
Hassel, B1
Hillman, J1
Aneman, O1
Persson, M1
Andersson, C1
Dabrosin, C1
Mellergård, P2
Eide, PK1
Bentsen, G1
Stanisic, M1
Stubhaug, A1
Zoremba, N1
Schnoor, J1
Berens, M1
Kuhlen, R1
Rossaint, R1
Fatar, M1
Stroick, M1
Griebe, M1
Alonso, A1
Kreisel, S1
Kern, R1
Hennerici, M1
Meairs, S1
Naruse, S1
Horikawa, Y1
Tanaka, C1
Hirakawa, K1
Nishikawa, H1
Watari, H1
Agostoni, A1
Hatashita, S2
Beley, P1
Bralet, J1
Marshall, LF1
Nishijima, M1
Tanaka, S1
Watanabe, T1
Yoshimoto, T1
Suzuki, J1
Misiuk, NS1
Kurgaev, VI1
Pediconi, MF1
Rodriguez de Turco, EB1
Bazan, NG1
Nakatomi, Y1
Winter, R1
Nau, R1
Hacke, W1
Otsubo, K1
Kashiwagi, F5
Muramatsu, H1
Terashi, A5
Kario, K1
Kodama, K1
Koide, M1
Matsuo, T1
Hillered, L1
Valtysson, J1
Enblad, P1
Persson, L1
Tsuda, Y1
Kitadai, M1
Hatanaka, Y1
Izumi, Y1
Nilsson, OG1
Brandt, L1
Ungerstedt, U2
Säveland, H1
a'Rogvi-Hansen, B1
D'Alessandro, G1
Corso, G1
Bottacchi, E1
Schulz, MK1
Wang, LP1
Tange, M1
Restrepo, L1
Silverman, IE1
Ståhl, N1
Hallström, A1
Suzuki, M2
Sato, K1
Dohi, S1
Sato, T1
Matsuura, A1
Hiraide, A1
Schellinger, PD1
Steiner, T1
Sakowitz, OW1
Kiening, KL1
Benndorf, G1
Lanksch, WR1
Battistini, N1
Memezawa, H1
Shimizu, J3
Kamiya, T1
Yamashita, T1
Eguchi, Y1
Kashiwagi, S1
Takasago, T1
Nakano, S1
Hayashi, M1
Urakawa, M1
Shiroyama, Y1
Ito, H1
Hara, H1
Kogure, K1
Kato, H1
Ozaki, A1
Sukamoto, T1
Ohta, K1
Gotoh, F1
Tomita, M1
Tanahashi, N1
Kobari, M1
Shinohara, T1
Terayama, Y1
Mihara, B1
Suzuki, S2
Iida, S1
Frithz, G1
Nagazumi, A1
Dietis, A1
Ehteshami, S1
Harrison, MJ1
Perinpanayagam, NI1
Fujishima, M1
Ishitsuka, T1
Yoshida, F1
Ibayashi, S1
Shiokawa, O1
Sadoshima, S1
Wang, RR1
Hao, Y1
Chen, J1
Wang, MQ1
Zheng, RY1
Shi, LS1
He, J1
Bilenko, NP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779]12 participants (Actual)Observational2017-08-28Completed
Cerebral Autoregulation in Patients With Aneurysmal SubArachnoid Haemorrhage[NCT03987139]45 participants (Anticipated)Interventional2019-06-15Active, not recruiting
Ketone Esters for Optimization of Cognitive Performance in Hypoxia[NCT03659825]16 participants (Anticipated)Interventional2018-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for glycerol and Brain Ischemia

ArticleYear
[Use of intracerebral microdialysis in severe traumatic brain injury].
    No shinkei geka. Neurological surgery, 2010, Volume: 38, Issue:9

    Topics: Adult; Aged; Animals; Brain Chemistry; Brain Injuries; Brain Ischemia; Glucose; Glutamic Acid; Glyce

2010
Glycerol for acute stroke.
    The Cochrane database of systematic reviews, 2004, Issue:2

    Topics: Brain Edema; Brain Ischemia; Glycerol; Humans; Randomized Controlled Trials as Topic; Stroke

2004
Assessment of critical thresholds for cerebral perfusion pressure by performing bedside monitoring of cerebral energy metabolism.
    Neurosurgical focus, 2003, Dec-15, Volume: 15, Issue:6

    Topics: Blood Pressure; Blood-Brain Barrier; Body Water; Brain; Brain Chemistry; Brain Edema; Brain Injuries

2003
[Treatment of ischemic cerebral infarct with glycerine].
    Der Nervenarzt, 1995, Volume: 66, Issue:8

    Topics: Administration, Oral; Brain; Brain Edema; Brain Ischemia; Cerebral Infarction; Glycerol; Humans; Inf

1995
Glycerol for acute ischaemic stroke.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Brain Edema; Brain Ischemia; Glycerol; Humans; Stroke

2000
Glycerol for acute stroke.
    The Cochrane database of systematic reviews, 2000, Issue:4

    Topics: Brain Edema; Brain Ischemia; Glycerol; Humans; Randomized Controlled Trials as Topic; Stroke

2000

Trials

4 trials available for glycerol and Brain Ischemia

ArticleYear
Effect of glycerol on ischemic cerebral edema assessed by magnetic resonance imaging.
    Journal of the neurological sciences, 2003, May-15, Volume: 209, Issue:1-2

    Topics: Aged; Brain; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebral Ventricles; Drug Combination

2003
Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study.
    Stroke, 2004, Volume: 35, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Flow Velocity; Brain; Brain Ischemia; Cerebrovascular Circulation; Ex

2004
Thrombin inhibition in the acute phase of ischaemic stroke using argatroban.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1995, Volume: 6, Issue:5

    Topics: Aged; Antithrombins; Arginine; Brain Ischemia; Double-Blind Method; Female; Fibrin Fibrinogen Degrad

1995
Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2000, Volume: 93, Issue:5

    Topics: Adult; Aged; Brain; Brain Death; Brain Ischemia; Cerebral Angiography; Extracellular Space; Glucose;

2000

Other Studies

53 other studies available for glycerol and Brain Ischemia

ArticleYear
Noggin-mediated effects on metabolite profiles of microglia and oligodendrocytes after ischemic insult.
    Journal of pharmaceutical and biomedical analysis, 2023, Feb-05, Volume: 224

    Topics: Brain Ischemia; Glucose; Glycerol; Humans; Ischemia; Microglia; Oligodendroglia

2023
Noggin-mediated effects on metabolite profiles of microglia and oligodendrocytes after ischemic insult.
    Journal of pharmaceutical and biomedical analysis, 2023, Feb-05, Volume: 224

    Topics: Brain Ischemia; Glucose; Glycerol; Humans; Ischemia; Microglia; Oligodendroglia

2023
Noggin-mediated effects on metabolite profiles of microglia and oligodendrocytes after ischemic insult.
    Journal of pharmaceutical and biomedical analysis, 2023, Feb-05, Volume: 224

    Topics: Brain Ischemia; Glucose; Glycerol; Humans; Ischemia; Microglia; Oligodendroglia

2023
Noggin-mediated effects on metabolite profiles of microglia and oligodendrocytes after ischemic insult.
    Journal of pharmaceutical and biomedical analysis, 2023, Feb-05, Volume: 224

    Topics: Brain Ischemia; Glucose; Glycerol; Humans; Ischemia; Microglia; Oligodendroglia

2023
The Importance of Probe Location for the Interpretation of Cerebral Microdialysis Data in Subarachnoid Hemorrhage Patients.
    Neurocritical care, 2020, Volume: 32, Issue:1

    Topics: Aged; Aneurysm, Ruptured; Brain; Brain Edema; Brain Ischemia; Cohort Studies; Female; Glucose; Gluta

2020
Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage.
    Acta neurologica Scandinavica, 2014, Volume: 130, Issue:3

    Topics: Aged; Biomarkers; Brain Ischemia; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Human

2014
Venous obstruction and cerebral perfusion during experimental cardiopulmonary bypass.
    Interactive cardiovascular and thoracic surgery, 2010, Volume: 11, Issue:5

    Topics: Animals; Biomarkers; Blood Gas Analysis; Blood Glucose; Brain Ischemia; Cardiopulmonary Bypass; Cent

2010
Acute depression of energy metabolism after microdialysis probe implantation is distinct from ischemia-induced changes in mouse brain.
    Neurochemical research, 2011, Volume: 36, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Energy Metabolism; Glucose; Glutamates; Glycero

2011
Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue.
    Neurocritical care, 2011, Volume: 14, Issue:3

    Topics: Blood Glucose; Brain Concussion; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Epoprostenol; F

2011
Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study.
    Stroke, 2002, Volume: 33, Issue:8

    Topics: Aged; Amides; Arachidonic Acids; Brain; Brain Chemistry; Brain Ischemia; Endocannabinoids; Ethanolam

2002
Fructose-1,6-bisphosphate for improved outcome after hypothermic circulatory arrest in pigs.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 125, Issue:3

    Topics: Animals; Brain Chemistry; Brain Ischemia; Calcium; Creatine Kinase; Creatine Kinase, MB Form; Diseas

2003
Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebrovascular Circulation; Corpus

2003
Effect of hypervolaemic haemodilution on cerebral glutamate, glycerol, lactate and free radicals in heatstroke rats.
    Clinical science (London, England : 1979), 2004, Volume: 106, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Free Radicals; Glutamic Acid; Glycerol;

2004
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
    Journal of neurosurgery, 2004, Volume: 100, Issue:1

    Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Ma

2004
Beneficial effect of L-arginine for stroke-like episode in MELAS.
    Brain & development, 2004, Volume: 26, Issue:7

    Topics: Adolescent; Arginine; Brain; Brain Ischemia; Drug Therapy, Combination; Energy Metabolism; Female; G

2004
Heat shock pretreatment may protect against heatstroke-induced circulatory shock and cerebral ischemia by reducing oxidative stress and energy depletion.
    Shock (Augusta, Ga.), 2005, Volume: 23, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Catechols; Cerebrovascular Circulation; Glut

2005
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:4

    Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid;

2005
[Recent advances in regional cerebral monitoring in the neurocritical patient: brain tissue oxygen pressure monitoring, cerebral microdialysis and near-infrared spectroscopy].
    Neurocirugia (Asturias, Spain), 2005, Volume: 16, Issue:5

    Topics: Brain; Brain Chemistry; Brain Infarction; Brain Injuries; Brain Ischemia; Cerebrovascular Circulatio

2005
Formation of glycerol from glucose in rat brain and cultured brain cells. Augmentation with kainate or ischemia.
    Journal of neurochemistry, 2007, Volume: 101, Issue:6

    Topics: Animals; Astrocytes; Brain; Brain Ischemia; Carbon Isotopes; Cells, Cultured; Cerebellum; Glucose; G

2007
Variations in the response of interleukins in neurosurgical intensive care patients monitored using intracerebral microdialysis.
    Journal of neurosurgery, 2007, Volume: 106, Issue:5

    Topics: Brain; Brain Concussion; Brain Injuries; Brain Ischemia; Cathepsin D; Critical Care; Enzyme-Linked I

2007
Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:9

    Topics: Aged; Brain; Brain Ischemia; Female; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Intracr

2007
Brain metabolism during a decrease in cerebral perfusion pressure caused by an elevated intracranial pressure in the porcine neocortex.
    Anesthesia and analgesia, 2007, Volume: 105, Issue:3

    Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Glucose; Glutamic Acid

2007
Effect of combined ultrasound and microbubbles treatment in an experimental model of cerebral ischemia.
    Ultrasound in medicine & biology, 2008, Volume: 34, Issue:9

    Topics: Animals; Biomarkers; Brain Ischemia; Glutamic Acid; Glycerol; Infarction, Middle Cerebral Artery; La

2008
Measurements of in vivo energy metabolism in experimental cerebral ischaemia using 31P-NMR for the evaluation of protective effects of perfluorochemicals and glycerol.
    Neurological research, 1984, Volume: 6, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain Ischemia; Drug Combinations; Electroen

1984
[Current status of medical treatment].
    Minerva medica, 1980, Jul-31, Volume: 71, Issue:29

    Topics: Aminophylline; Animals; Anticoagulants; Aspirin; Barbiturates; Brain Ischemia; Cerebrovascular Disor

1980
[Protective effects of barbiturate, mannitol and glycerol on experimental global cerebral ischemia (Part I)].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:12

    Topics: Animals; Brain Ischemia; Cats; Glycerol; Mannitol; Thiopental

1982
[Protective effects of barbiturate, mannitol and glycerol on experimental global cerebral ischemia (Part II)].
    Neurologia medico-chirurgica, 1982, Volume: 22, Issue:12

    Topics: Animals; Brain Ischemia; Cats; Glycerol; Mannitol; Thiopental

1982
[Release and metabolism of brain noradrenaline during experimental ischemia. Effect of glycerol treatment].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1982, Volume: 176, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Glycerol; Male; Norepinephrine; Rats; Rats, Inbred Strains

1982
Treatment of brain swelling and brain edema in man.
    Advances in neurology, 1980, Volume: 28

    Topics: Barbiturates; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebral Infarction; Dexamethasone; Diur

1980
[Sequential changes in nerve cells during complete ischemia and the preventive effects of various drugs on cerebral infarction (author's transl)].
    No to shinkei = Brain and nerve, 1981, Volume: 33, Issue:3

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dogs; Glucose; Glycerol; Manni

1981
[Effect of glycerol, mannitol, and lasix on cerebrospinal fluid pressure in the acute period of a stroke].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:8

    Topics: Acute Disease; Brain Edema; Brain Ischemia; Cerebral Hemorrhage; Female; Furosemide; Glycerol; Human

1981
Diffusion of intracerebrally injected [1-14C]arachidonic acid and [2-3H]glycerol in the mouse brain. Effects of ischemia and electroconvulsive shock.
    Neurochemical research, 1982, Volume: 7, Issue:12

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Brain Ischemia; Carbon Radioisotopes; Diffusion

1982
[Effect of recirculation on experimental cerebral ischemia. 3. Therapy].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1982, Volume: 73, Issue:9

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulatio

1982
Comparison of the effects of glycerol, mannitol, and urea on ischemic hippocampal damage in gerbils.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Animals; Brain Edema; Brain Ischemia; Cell Survival; Gerbillinae; Glycerol; Hippocampus; Hypertonic

1994
Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain.
    Journal of neurology, neurosurgery, and psychiatry, 1998, Volume: 64, Issue:4

    Topics: Acute Disease; Aged; Biomarkers; Blood-Brain Barrier; Brain Chemistry; Brain Ischemia; Female; Glyce

1998
Effects of mannitol and glycerol on cerebral energy metabolism in gerbils.
    Acta neurologica Scandinavica, 1998, Volume: 98, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Energy Met

1998
Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration.
    Neurosurgery, 1999, Volume: 45, Issue:5

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain Ischemia; Cerebral Cortex; Female; Glutamic Acid; Glyc

1999
Could flumazenil reverse neurological deficits in acute cerebral ischemia?
    Italian journal of neurological sciences, 1999, Volume: 20, Issue:1

    Topics: Acute Disease; Brain Ischemia; Carotid Artery Thrombosis; Carotid Artery, Internal; Cerebral Angiogr

1999
Osmotherapy: a call to arms.
    Stroke, 2001, Volume: 32, Issue:3

    Topics: Blood Viscosity; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Clinical Trials as Topic; Glycero

2001
Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:8

    Topics: Adult; Aged; Brain; Brain Injuries; Brain Ischemia; Energy Metabolism; Female; Glucose; Glycerol; Hu

2001
Effect of beta-hydroxybutyrate, a cerebral function improving agent, on cerebral hypoxia, anoxia and ischemia in mice and rats.
    Japanese journal of pharmacology, 2001, Volume: 87, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Blood Pressure; Body Water; Brain; Brain Ede

2001
Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction.
    Cerebrovascular diseases (Basel, Switzerland), 2001, Volume: 12, Issue:4

    Topics: Adult; Brain Ischemia; Extracellular Space; Glutamic Acid; Glycerol; Humans; Hypothermia, Induced; I

2001
Bedside microdialysis: a tool to monitor cerebral metabolism in subarachnoid hemorrhage patients?
    Critical care medicine, 2002, Volume: 30, Issue:5

    Topics: Adult; Aged; Brain; Brain Ischemia; Environmental Monitoring; Female; Glasgow Coma Scale; Glucose; G

2002
Therapy of ischemic brain edema.
    European neurology, 1978, Volume: 17 Suppl 1

    Topics: Brain Edema; Brain Ischemia; Cerebrovascular Disorders; Drug Evaluation; Glycerol; Humans; Infusions

1978
Effect of a prostacyclin derivative (OP-41483) and a hyperosmotic agent (glycerol) on brain edema and metabolism in cerebral ischemia.
    Japanese circulation journal, 1992, Volume: 56, Issue:12

    Topics: Animals; Body Water; Brain; Brain Edema; Brain Ischemia; Cerebral Cortex; Drug Therapy, Combination;

1992
Effect of a new hyperosmotic agent, NIK-242 injection, on brain water content, metabolites and cerebral blood flow in cerebral ischemia in the spontaneously hypertensive rat.
    Japanese circulation journal, 1991, Volume: 55, Issue:12

    Topics: Animals; Body Water; Brain; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Erythritol; Gl

1991
[The effect of glycerol on local cerebral blood flow in patients with chronic ischemic cerebrovascular lesions].
    No to shinkei = Brain and nerve, 1991, Volume: 43, Issue:11

    Topics: Adult; Aged; Brain Ischemia; Cerebrovascular Circulation; Chronic Disease; Female; Glycerol; Humans;

1991
Amelioration of brain damage after focal ischemia in the rat by a novel inhibitor of lipid peroxidation.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Animals; Brain; Brain Edema; Brain Injuries; Brain Ischemia; Cerebral Arteries; Glycerol; In Vitro T

1991
Effect of glycerol on the hemodynamics of acutely induced ischemic area in the cerebral cortex of cats.
    Advances in neurology, 1990, Volume: 52

    Topics: Animals; Brain Edema; Brain Ischemia; Cats; Cerebrovascular Circulation; Drug Synergism; Female; Fru

1990
Effect of timing and dose of the hyperosmotic agent glycerol on experimental ischemic brain edema and metabolites.
    Advances in neurology, 1990, Volume: 52

    Topics: Animals; Brain Chemistry; Brain Edema; Brain Ischemia; Glycerol; Hypertonic Solutions

1990
Important new treatments for acute ischaemic stroke.
    British medical journal (Clinical research ed.), 1988, Jan-16, Volume: 296, Issue:6616

    Topics: Activities of Daily Living; Aged; Brain Ischemia; Glycerol; Humans; Prognosis

1988
[Effect of glycerol administration on experimental cerebral ischemia--Part 1. Studies on lipid peroxides, prostaglandins, brain edema and brain metabolites].
    No to shinkei = Brain and nerve, 1988, Volume: 40, Issue:2

    Topics: Animals; Body Water; Brain; Brain Edema; Brain Ischemia; Glycerol; Lipid Peroxides; Male; Prostaglan

1988
The effect of isovolaemic haemodilution and intravenous glycerol on the sequelae of middle cerebral artery occlusion in the rat.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:4

    Topics: Animals; Arterial Occlusive Diseases; Brain Ischemia; Cerebral Arterial Diseases; Combined Modality

1986
Effects of intravenous glycerol on cerebral blood flow and tissue metabolism in acute cerebral ischemia in spontaneously hypertensive rats.
    Angiology, 1986, Volume: 37, Issue:2

    Topics: Acute Disease; Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation;

1986
Sex differences in the effects of the moon on ischemic stroke incidence: new findings from Beijing, China.
    Chronobiology international, 2020, Volume: 37, Issue:6

    Topics: Beijing; Brain Ischemia; China; Circadian Rhythm; Female; Humans; Ischemic Stroke; Male; Moon; Retro

2020
[Monthly rhythms of exacerbations and debuts of some diseases and sudden death].
    Klinicheskaia meditsina, 2003, Volume: 81, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Coagulation; Brain Ischemia; Death, Sudden; Female

2003