glycerol has been researched along with Brain Injuries in 67 studies
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to determine the effects of a hyperosmotic agent, 10% glycerol, on both brain energy metabolism and intracellular pH (pHi) in experimental vasogenic brain edema." | 7.69 | 31P-magnetic resonance spectroscopic study on the effect of glycerol on cold-induced brain edema. ( Asakura, T; Fujimoto, T; Kamezawa, T; Kasamo, S; Niiro, M; Yatsushiro, K, 1994) |
| "To clarify the pharmacokinetics and effect of ICP reduction of glycerol administered orally, the serum concentration of glycerol was measured by the enzymatic method and ICP was measured by the subdural balloon method in severe head injured patients with brain edema and increased ICP." | 7.69 | Pharmacokinetics and pharmacodynamics of serum glycerol in patients with brain edema: comparison of oral and intravenous administration. ( Kitahara, Y; Kobayashi, T; Kondo, R; Morii, S; Murase, S; Ohwada, T; Takagi, H; Tomonaga, F; Tsuyusaki, H; Yoshiyama, Y, 1994) |
| "Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percussion, and the rats were divided into groups treated with magnolol (2 mg/kg, intravenously) or vehicle." | 3.79 | Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013) |
| "Traumatic brain injury (TBI) induces brain edema via water and glycerol transport channels, called aquaporins (AQPs)." | 3.78 | Glycerol accumulation in edema formation following diffuse traumatic brain injury. ( Ali, A; Ding, JY; Ding, Y; Dornbos, D; Geng, X; Guthikonda, M; Konakondla, S; Kreipke, CW; Peng, C; Rafols, JA; Schafer, S; Sikharam, C; Zwagerman, NT, 2012) |
| "An LP ratio >25 and glycerol >100 micromol/L, but not glutamate >12 micromol/L, were associated with significantly higher risk of imminent intracranial hypertension (odds ratio: 9." | 3.74 | Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study. ( Belli, A; Kitchen, N; Petzold, A; Russo, S; Sen, J; Smith, M, 2008) |
| "The aim of the present study was to determine the effects of a hyperosmotic agent, 10% glycerol, on both brain energy metabolism and intracellular pH (pHi) in experimental vasogenic brain edema." | 3.69 | 31P-magnetic resonance spectroscopic study on the effect of glycerol on cold-induced brain edema. ( Asakura, T; Fujimoto, T; Kamezawa, T; Kasamo, S; Niiro, M; Yatsushiro, K, 1994) |
| "To clarify the pharmacokinetics and effect of ICP reduction of glycerol administered orally, the serum concentration of glycerol was measured by the enzymatic method and ICP was measured by the subdural balloon method in severe head injured patients with brain edema and increased ICP." | 3.69 | Pharmacokinetics and pharmacodynamics of serum glycerol in patients with brain edema: comparison of oral and intravenous administration. ( Kitahara, Y; Kobayashi, T; Kondo, R; Morii, S; Murase, S; Ohwada, T; Takagi, H; Tomonaga, F; Tsuyusaki, H; Yoshiyama, Y, 1994) |
| "Glycerol is considered to be a marker of cell membrane degradation and thus cellular lysis." | 2.71 | Association between elevated brain tissue glycerol levels and poor outcome following severe traumatic brain injury. ( Alves, OL; Bullock, R; Clausen, T; Doppenberg, E; Reinert, M; Zauner, A, 2005) |
| "Glycerol is an integral component of cell membranes." | 2.46 | [Use of intracerebral microdialysis in severe traumatic brain injury]. ( Abe, Y; Kawai, N; Kawakita, K; Kuroda, Y; Tamiya, T; Yano, T, 2010) |
| "The mannitol-treated rats showed significant improvement in motor function." | 1.39 | Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury. ( Date, I; Haruma, J; Hishikawa, T; Kameda, M; Liu, K; Nishibori, M; Okuma, Y; Sugiu, K; Tokunaga, K; Toyoshima, A; Wang, F; Yasuhara, T, 2013) |
| " Reduced IC combined with intracranial volume insults leads to metabolic disturbances in a rat model." | 1.36 | Metabolic effects of a late hypotensive insult combined with reduced intracranial compliance following traumatic brain injury in the rat. ( Contant, CF; Enblad, P; Goiny, M; Nilsson, P; Piper, I; Salci, K, 2010) |
| "Glycerol is a marker of cellular membrane breakdown." | 1.31 | Delayed increase in extracellular glycerol with post-traumatic electrographic epileptic activity: support for the theory that seizures induce secondary injury. ( Becker, DP; Bergsneider, M; Glenn, T; Hovda, DA; Kelly, D; Martin, NA; Nenov, V; Vespa, P, 2002) |
| " (b) In every group, it appeared that the slower the infusion rate of the same dosage became, the longer the reduction of ICP lasted." | 1.28 | Clinical study of mannitol and glycerol on raised intracranial pressure and on their rebound phenomenon. ( Nakazawa, S; Node, Y, 1990) |
| "Cerebral edema was assessed 0." | 1.28 | Influence of thermal stress and various agents on the brain edema formation in rats following a cryogenic brain lesion. ( Chiu, WT; Lin, LS; Lin, MT; Shih, CJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (16.42) | 18.7374 |
| 1990's | 16 (23.88) | 18.2507 |
| 2000's | 19 (28.36) | 29.6817 |
| 2010's | 19 (28.36) | 24.3611 |
| 2020's | 2 (2.99) | 2.80 |
| Authors | Studies |
|---|---|
| Hägglund, L | 1 |
| Olivecrona, M | 1 |
| Koskinen, LD | 1 |
| Thango, NS | 1 |
| Rohlwink, UK | 1 |
| Dlamini, L | 1 |
| Tshavhungwe, MP | 1 |
| Banderker, E | 1 |
| Salie, S | 1 |
| Enslin, JMN | 1 |
| Figaji, AA | 1 |
| Boruczkowski, D | 1 |
| Pujal, JM | 1 |
| Zdolińska-Malinowska, I | 1 |
| Andelius, TCK | 1 |
| Pedersen, MV | 1 |
| Bøgh, N | 1 |
| Omann, C | 1 |
| Hjortdal, VE | 1 |
| Pedersen, M | 1 |
| Kyng, KJ | 1 |
| Henriksen, TB | 1 |
| Wang, CC | 1 |
| Lin, KC | 1 |
| Lin, BS | 1 |
| Chio, CC | 1 |
| Kuo, JR | 1 |
| Okuma, Y | 1 |
| Wang, F | 1 |
| Toyoshima, A | 1 |
| Kameda, M | 1 |
| Hishikawa, T | 1 |
| Tokunaga, K | 1 |
| Sugiu, K | 1 |
| Liu, K | 1 |
| Haruma, J | 1 |
| Nishibori, M | 1 |
| Yasuhara, T | 1 |
| Date, I | 1 |
| Liang, MY | 1 |
| Tang, ZX | 1 |
| Chen, GX | 1 |
| Rong, J | 1 |
| Yao, JP | 1 |
| Chen, Z | 1 |
| Wu, ZK | 1 |
| Cheshire, EC | 1 |
| Malcomson, RD | 1 |
| Joseph, S | 1 |
| Biggs, MJ | 1 |
| Adlam, D | 1 |
| Rutty, GN | 1 |
| Kawai, N | 1 |
| Kawakita, K | 1 |
| Yano, T | 1 |
| Abe, Y | 1 |
| Kuroda, Y | 1 |
| Tamiya, T | 1 |
| Salci, K | 3 |
| Enblad, P | 2 |
| Goiny, M | 2 |
| Contant, CF | 2 |
| Piper, I | 2 |
| Nilsson, P | 2 |
| Clausen, F | 1 |
| Hillered, L | 3 |
| Gustafsson, J | 1 |
| Timofeev, I | 1 |
| Carpenter, KL | 1 |
| Nortje, J | 1 |
| Al-Rawi, PG | 1 |
| O'Connell, MT | 1 |
| Czosnyka, M | 1 |
| Smielewski, P | 1 |
| Pickard, JD | 1 |
| Menon, DK | 1 |
| Kirkpatrick, PJ | 1 |
| Gupta, AK | 1 |
| Hutchinson, PJ | 1 |
| Larach, DB | 1 |
| Kofke, WA | 1 |
| Le Roux, P | 1 |
| Yokobori, S | 1 |
| Watanabe, A | 1 |
| Matsumoto, G | 1 |
| Onda, H | 1 |
| Masuno, T | 1 |
| Fuse, A | 1 |
| Kushimoto, S | 1 |
| Yokota, H | 1 |
| Mellergård, P | 4 |
| Sjögren, F | 2 |
| Hillman, J | 3 |
| Revuelto-Rey, J | 1 |
| Egea-Guerrero, JJ | 1 |
| Muñoz-Sánchez, MA | 1 |
| Murillo-Cabezas, F | 1 |
| Omerhodzić, I | 1 |
| Dizdarević, K | 1 |
| Rotim, K | 1 |
| Hajdarpasić, E | 1 |
| Niksić, M | 1 |
| Bejtić-Custović, E | 1 |
| Selimović, E | 1 |
| Custović, M | 1 |
| Tanguy, M | 1 |
| Seguin, P | 1 |
| Laviolle, B | 1 |
| Bleichner, JP | 1 |
| Morandi, X | 1 |
| Malledant, Y | 1 |
| Ali, A | 1 |
| Konakondla, S | 1 |
| Zwagerman, NT | 1 |
| Peng, C | 1 |
| Schafer, S | 1 |
| Ding, JY | 1 |
| Dornbos, D | 1 |
| Sikharam, C | 1 |
| Geng, X | 1 |
| Guthikonda, M | 1 |
| Kreipke, CW | 1 |
| Rafols, JA | 1 |
| Ding, Y | 1 |
| Stein, NR | 1 |
| McArthur, DL | 1 |
| Etchepare, M | 1 |
| Vespa, PM | 1 |
| Blanié, A | 1 |
| Vigué, B | 2 |
| Benhamou, D | 2 |
| Duranteau, J | 2 |
| Geeraerts, T | 2 |
| Vespa, P | 1 |
| Martin, NA | 1 |
| Nenov, V | 1 |
| Glenn, T | 1 |
| Bergsneider, M | 1 |
| Kelly, D | 1 |
| Becker, DP | 1 |
| Hovda, DA | 1 |
| Lourido, J | 1 |
| Ederoth, P | 1 |
| Sundvall, N | 1 |
| Ungerstedt, U | 4 |
| Nordström, CH | 5 |
| Diaz-Parejo, P | 1 |
| Ståhl, N | 3 |
| Xu, W | 1 |
| Reinstrup, P | 1 |
| Peerdeman, SM | 1 |
| Girbes, AR | 1 |
| Polderman, KH | 1 |
| Vandertop, WP | 1 |
| Clausen, T | 1 |
| Alves, OL | 1 |
| Reinert, M | 1 |
| Doppenberg, E | 1 |
| Zauner, A | 1 |
| Bullock, R | 1 |
| Poca, MA | 1 |
| Sahuquillo, J | 1 |
| Mena, MP | 1 |
| Vilalta, A | 1 |
| Riveiro, M | 1 |
| Milos, P | 1 |
| Yu, ZQ | 1 |
| Anderson, C | 1 |
| Contant, C | 1 |
| Phillips, DJ | 1 |
| Nguyen, P | 1 |
| Adamides, AA | 1 |
| Bye, N | 1 |
| Rosenfeld, JV | 1 |
| Kossmann, T | 1 |
| Vallance, S | 1 |
| Murray, L | 1 |
| Morganti-Kossmann, MC | 1 |
| Aneman, O | 1 |
| Persson, M | 1 |
| Andersson, C | 1 |
| Dabrosin, C | 1 |
| Wang, Q | 2 |
| Li, AL | 2 |
| Zhi, DS | 2 |
| Huang, HL | 2 |
| Friggeri, A | 1 |
| Mazoit, JX | 1 |
| Merenda, A | 1 |
| Gugliotta, M | 1 |
| Holloway, R | 1 |
| Levasseur, JE | 1 |
| Alessandri, B | 1 |
| Sun, D | 1 |
| Bullock, MR | 1 |
| Belli, A | 1 |
| Sen, J | 1 |
| Petzold, A | 1 |
| Russo, S | 1 |
| Kitchen, N | 1 |
| Smith, M | 1 |
| Millet, A | 1 |
| Slósarek, J | 1 |
| Wang, JY | 2 |
| Chen, JL | 2 |
| Kamezawa, T | 1 |
| Asakura, T | 2 |
| Yatsushiro, K | 2 |
| Niiro, M | 2 |
| Kasamo, S | 1 |
| Fujimoto, T | 2 |
| Tsuyusaki, H | 2 |
| Kondo, R | 1 |
| Murase, S | 1 |
| Yoshiyama, Y | 1 |
| Kobayashi, T | 1 |
| Takagi, H | 2 |
| Kitahara, Y | 1 |
| Morii, S | 1 |
| Tomonaga, F | 1 |
| Ohwada, T | 1 |
| Marklund, N | 1 |
| Lewén, A | 2 |
| Biestro, A | 1 |
| Alberti, R | 1 |
| Galli, R | 1 |
| Cancela, M | 1 |
| Soca, A | 1 |
| Panzardo, H | 1 |
| Borovich, B | 1 |
| Tateishi, A | 1 |
| Soejima, Y | 1 |
| Taira, Y | 1 |
| Nakashima, K | 1 |
| Fujisawa, H | 1 |
| Tsuchida, E | 1 |
| Maekawa, T | 1 |
| Ito, H | 1 |
| Nara, I | 1 |
| Shiogai, T | 1 |
| Hara, M | 1 |
| Saito, I | 1 |
| Endo, M | 1 |
| Kitahara, T | 1 |
| Aquilani, R | 1 |
| Viglio, S | 1 |
| Iadarola, P | 1 |
| Guarnaschelli, C | 1 |
| Arrigoni, N | 1 |
| Fugazza, G | 1 |
| Catapano, M | 1 |
| Boschi, F | 1 |
| Dossena, M | 1 |
| Pastoris, O | 1 |
| Hallström, A | 1 |
| Leitch, AG | 1 |
| McLennan, JE | 1 |
| Balkenhol, S | 1 |
| Loudon, RG | 1 |
| McLaurin, RL | 1 |
| Feuer, H | 1 |
| Oppido, PA | 1 |
| Delfini, R | 1 |
| Innocenzi, G | 1 |
| Di Giugno, G | 1 |
| Pecori-Giraldi, J | 1 |
| Santoro, A | 1 |
| Virno, M | 1 |
| Cantore, GP | 1 |
| Hara, H | 1 |
| Kogure, K | 1 |
| Kato, H | 1 |
| Ozaki, A | 1 |
| Sukamoto, T | 1 |
| Robertson, CS | 1 |
| Goodman, JC | 1 |
| Narayan, RK | 1 |
| Grossman, RG | 1 |
| Sasahira, M | 1 |
| Terada, K | 1 |
| Uchimura, K | 1 |
| Node, Y | 1 |
| Nakazawa, S | 1 |
| Calon, B | 1 |
| Pottecher, T | 1 |
| Frey, A | 1 |
| Ravanello, J | 1 |
| Otteni, JC | 1 |
| Bach, AC | 1 |
| Lin, LS | 1 |
| Chiu, WT | 1 |
| Shih, CJ | 1 |
| Lin, MT | 1 |
| Shats, DM | 1 |
| Ovchinnikova, LF | 1 |
| Meyer, JS | 1 |
| Fukuuchi, Y | 1 |
| Shimazu, K | 1 |
| Mathew, NT | 1 |
| Ouchi, T | 1 |
| Kents, VV | 1 |
| Kolik, LM | 1 |
| Metzel, E | 1 |
| Zimmermann, WE | 1 |
| Puff, G | 1 |
| Meyer, KJ | 1 |
| Troupp, H | 1 |
| Valtonen, S | 1 |
| Vapalahti, M | 1 |
| Obes Polleri, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prostacyclin Treatment in Severe Traumatic Brain Injury: a Microdialysis and Outcome Study[NCT01363583] | Phase 1 | 48 participants (Actual) | Interventional | 2002-01-31 | Completed | ||
| Multimodality Monitoring Directed Management of Patients Suffering From Traumatic Brain Injury[NCT02993549] | 100 participants (Anticipated) | Observational | 2017-09-16 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for glycerol and Brain Injuries
| Article | Year |
|---|---|
Autologous cord blood in children with cerebral palsy: a review.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Brain Diseases; Brain Injuries; Carnitine; Cerebral Pal | 2019 |
[Use of intracerebral microdialysis in severe traumatic brain injury].
Topics: Adult; Aged; Animals; Brain Chemistry; Brain Injuries; Brain Ischemia; Glucose; Glutamic Acid; Glyce | 2010 |
[Cerebral microdialysis in the current clinical setting].
Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Injuries; Cerebrovascular Disorders; Critical | 2012 |
Assessment of critical thresholds for cerebral perfusion pressure by performing bedside monitoring of cerebral energy metabolism.
Topics: Blood Pressure; Blood-Brain Barrier; Body Water; Brain; Brain Chemistry; Brain Edema; Brain Injuries | 2003 |
[Effect of osmotic diuretics, enzyme-inhibiting diuretics and neuroleptics on cerebral perfusion pressure].
Topics: Acetazolamide; Adrenal Cortex Hormones; Animals; Antipsychotic Agents; Brain Edema; Brain Injuries; | 1983 |
Mechanisms of hyperventilation in head injury: case report and review.
Topics: Adult; Brain Concussion; Brain Edema; Brain Injuries; Brain Stem; Cerebral Cortex; Chemoreceptor Cel | 1979 |
Early management of pediatric head injury. Physiologic aspects.
Topics: Brain Edema; Brain Injuries; Carbon Dioxide; Child; Craniocerebral Trauma; Dexamethasone; Glycerol; | 1975 |
8 trials available for glycerol and Brain Injuries
| Article | Year |
|---|---|
Correlation of Cerebral and Subcutaneous Glycerol in Severe Traumatic Brain Injury and Association with Tissue Damage.
Topics: Biomarkers; Brain Injuries; Brain Injuries, Traumatic; Glasgow Coma Scale; Glycerol; Humans; Phospho | 2022 |
Cerebral microdialysis: perioperative monitoring and treatment of severe neurosurgical patient.
Topics: Brain Injuries; Glucose; Glycerol; Humans; Intracranial Hemorrhage, Traumatic; Lactic Acid; Microdia | 2011 |
Cerebral microdialysis effects of propofol versus midazolam in severe traumatic brain injury.
Topics: Adult; Biomarkers; Brain Chemistry; Brain Injuries; Cerebral Cortex; Female; Glucose; Glutamic Acid; | 2012 |
Association between elevated brain tissue glycerol levels and poor outcome following severe traumatic brain injury.
Topics: Adult; Biomarkers; Brain Chemistry; Brain Injuries; Female; Glycerol; Humans; Male; Microdialysis; M | 2005 |
Effect of mild hypothermia on glucose metabolism and glycerol of brain tissue in patients with severe traumatic brain injury.
Topics: Adolescent; Adult; Brain; Brain Injuries; Glucose; Glycerol; Humans; Hypothermia, Induced; Microdial | 2007 |
Osmotherapy for increased intracranial pressure: comparison between mannitol and glycerol.
Topics: Adolescent; Adult; Brain Injuries; Female; Follow-Up Studies; Glasgow Coma Scale; Glycerol; Humans; | 1997 |
The effect of glucose administration on carbohydrate metabolism after head injury.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Blood Glucose; Brain Injuries; Carbohydrate Metab | 1991 |
Long-chain versus medium and long-chain triglyceride-based fat emulsion in parental nutrition of severe head trauma patients.
Topics: Blood Proteins; Blood Urea Nitrogen; Brain Injuries; Combined Modality Therapy; Critical Care; Doubl | 1990 |
52 other studies available for glycerol and Brain Injuries
| Article | Year |
|---|---|
Brain interstitial glycerol correlates with evolving brain injury in paediatric traumatic brain injury.
Topics: Adult; Brain; Brain Injuries; Brain Injuries, Traumatic; Child; Glycerol; Humans; Retrospective Stud | 2021 |
Consequence of insertion trauma - effect on early measurements when using intracerebral devices.
Topics: Animals; Brain; Brain Injuries; Glucose; Glycerol; Lactic Acid; Microdialysis; Prostheses and Implan | 2019 |
Resuscitation from experimental traumatic brain injury by magnolol therapy.
Topics: Animals; Apoptosis; Biphenyl Compounds; Brain Injuries; Disease Models, Animal; Free Radical Scaveng | 2013 |
Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Injuries; Glycerol; Male; Mannitol; Mesenchymal Stem Cell | 2013 |
Is selective antegrade cerebral perfusion superior to retrograde cerebral perfusion for brain protection during deep hypothermic circulatory arrest? Metabolic evidence from microdialysis.
Topics: Analysis of Variance; Animals; Brain; Brain Injuries; Circulatory Arrest, Deep Hypothermia Induced; | 2014 |
Optical clearing of the dura mater using glycerol: a reversible process to aid the post-mortem investigation of infant head injury.
Topics: Autopsy; Brain Injuries; Dura Mater; Glycerol; Hematoma, Subdural, Acute; Humans; Infant; Infant, Ne | 2015 |
Metabolic effects of a late hypotensive insult combined with reduced intracranial compliance following traumatic brain injury in the rat.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Disease Models, Animal; Glycerol; Hypotension; Hypoxant | 2010 |
Cerebral glucose metabolism after traumatic brain injury in the rat studied by 13C-glucose and microdialysis.
Topics: Anaerobiosis; Animals; Blood Glucose; Brain Damage, Chronic; Brain Injuries; Carbon Radioisotopes; E | 2011 |
Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients.
Topics: Adult; Biomarkers; Brain Injuries; Cerebral Cortex; Extracellular Fluid; Female; Glasgow Coma Scale; | 2011 |
Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: a review of available literature.
Topics: Aerobiosis; Anaerobiosis; Blood Glucose; Brain; Brain Injuries; Critical Care; Energy Metabolism; Ex | 2011 |
Time course of recovery from cerebral vulnerability after severe traumatic brain injury: a microdialysis study.
Topics: Analysis of Variance; Biomarkers; Body Temperature; Brain Injuries; Extracellular Fluid; Female; Gla | 2011 |
The cerebral extracellular release of glycerol, glutamate, and FGF2 is increased in older patients following severe traumatic brain injury.
Topics: Adult; Aged; Brain Injuries; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factor 2; | 2012 |
Glycerol accumulation in edema formation following diffuse traumatic brain injury.
Topics: 2-Methoxyestradiol; Animals; Aquaporins; Brain Edema; Brain Injuries; Disease Models, Animal; Estrad | 2012 |
Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation.
Topics: Adult; Blood Pressure; Brain; Brain Diseases, Metabolic; Brain Injuries; Cardiopulmonary Resuscitati | 2012 |
The frontal lobe and thalamus have different sensitivities to hypoxia-hypotension after traumatic brain injury: a microdialysis study in rats.
Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Frontal Lob | 2012 |
Delayed increase in extracellular glycerol with post-traumatic electrographic epileptic activity: support for the theory that seizures induce secondary injury.
Topics: Adult; Biomarkers; Brain Injuries; Electroencephalography; Epilepsy; Female; Glycerol; Humans; Male; | 2002 |
Correlation between blood glucose concentration and glucose concentration in subcutaneous adipose tissue evaluated with microdialysis during intensive care.
Topics: Adipose Tissue; Blood Glucose; Brain Injuries; Critical Care; Energy Metabolism; Glycerol; Humans; H | 2002 |
Cerebral energy metabolism during transient hyperglycemia in patients with severe brain trauma.
Topics: Blood Glucose; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Female; Glutamic Acid | 2003 |
Changes in cerebral interstitial glycerol concentration in head-injured patients; correlation with secondary events.
Topics: Adolescent; Adult; Aged; Brain; Brain Injuries; Female; Glycerol; Humans; Injury Severity Score; Mal | 2003 |
[Recent advances in regional cerebral monitoring in the neurocritical patient: brain tissue oxygen pressure monitoring, cerebral microdialysis and near-infrared spectroscopy].
Topics: Brain; Brain Chemistry; Brain Infarction; Brain Injuries; Brain Ischemia; Cerebrovascular Circulatio | 2005 |
Intracerebral microdialysis in neurosurgical intensive care patients utilising catheters with different molecular cut-off (20 and 100 kD).
Topics: Brain Chemistry; Brain Injuries; Catheters, Indwelling; Cerebral Cortex; Coma; Critical Care; Extrac | 2006 |
Low intracranial compliance increases the impact of intracranial volume insults to the traumatized brain: a microdialysis study in a traumatic brain injury rodent model.
Topics: Animals; Biomarkers; Brain; Brain Chemistry; Brain Edema; Brain Injuries; Cell Membrane; Cerebral He | 2006 |
Activin a release into cerebrospinal fluid in a subset of patients with severe traumatic brain injury.
Topics: Activins; Adolescent; Adult; Aged; Brain Injuries; Case-Control Studies; Female; Follistatin; Glutam | 2006 |
Variations in the response of interleukins in neurosurgical intensive care patients monitored using intracerebral microdialysis.
Topics: Brain; Brain Concussion; Brain Injuries; Brain Ischemia; Cathepsin D; Critical Care; Enzyme-Linked I | 2007 |
Posttraumatic brain vulnerability to hypoxia-hypotension: the importance of the delay between brain trauma and secondary insult.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Gl | 2008 |
Validation of brain extracellular glycerol as an indicator of cellular membrane damage due to free radical activity after traumatic brain injury.
Topics: Animals; Antioxidants; Brain; Brain Injuries; Cell Membrane; Cyclic N-Oxides; Extracellular Fluid; F | 2008 |
Extracellular glycerol in patients with severe traumatic brain injury.
Topics: Adolescent; Adult; Biomarkers; Brain Chemistry; Brain Injuries; Extracellular Space; Female; Glycero | 2008 |
Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study.
Topics: Biomarkers; Brain; Brain Injuries; Glutamic Acid; Glycerol; Humans; Intracranial Hypertension; Lacti | 2008 |
[Attempt to assess the efficacy of intracranial volumetric compensation taking into account the intracranial pressure instability index in patients after closed craniocerebral injuries].
Topics: Adolescent; Adult; Aged; Brain Injuries; Female; Glycerol; Homeostasis; Humans; Intracranial Pressur | 1981 |
Glycerol dehydrates oedematous as well as normal brain in dogs.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Cold Temperature; Dogs; Female; Glycerol; Infusions, In | 1994 |
31P-magnetic resonance spectroscopic study on the effect of glycerol on cold-induced brain edema.
Topics: Acid-Base Equilibrium; Adenosine Triphosphate; Animals; Brain Edema; Brain Injuries; Dogs; Energy Me | 1994 |
Pharmacokinetics and pharmacodynamics of serum glycerol in patients with brain edema: comparison of oral and intravenous administration.
Topics: Administration, Oral; Brain Edema; Brain Injuries; Glycerol; Humans; Infusions, Intravenous; Intracr | 1994 |
Glycerol as a marker for post-traumatic membrane phospholipid degradation in rat brain.
Topics: Analysis of Variance; Animals; Biomarkers; Brain; Brain Injuries; Glycerol; Male; Membrane Lipids; M | 1997 |
Feasibility of the titration method of mild hypothermia in severely head-injured patients with intracranial hypertension.
Topics: Adolescent; Adult; Aged; Brain Damage, Chronic; Brain Injuries; Combined Modality Therapy; Cross Inf | 1998 |
Involvement of reactive oxygen species in membrane phospholipid breakdown and energy perturbation after traumatic brain injury in the rat.
Topics: Analysis of Variance; Animals; Biomarkers; Brain Injuries; Disease Models, Animal; Disease Progressi | 1998 |
Comparative effects of hypothermia, barbiturate, and osmotherapy for cerebral oxygen metabolism, intracranial pressure, and cerebral perfusion pressure in patients with severe head injury.
Topics: Adolescent; Adult; Barbiturates; Blood Pressure; Brain; Brain Injuries; Child; Dose-Response Relatio | 1998 |
Pharmacokinetics of serum glycerol and changes of ICP: comparison of gastric and duodenal administration.
Topics: Brain Injuries; Enteral Nutrition; Glycerol; Humans; Intracranial Hypertension; Intracranial Pressur | 1998 |
Peripheral plasma amino acid abnormalities in rehabilitation patients with severe brain injury.
Topics: Adolescent; Adult; Aged; Amino Acids; Biomarkers; Brain Injuries; Carnitine; Disability Evaluation; | 2000 |
Brain energy metabolism during controlled reduction of cerebral perfusion pressure in severe head injuries.
Topics: Adolescent; Adult; Aged; Biomarkers; Brain Injuries; Cerebrovascular Circulation; Child; Child, Pres | 2001 |
Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions.
Topics: Adult; Aged; Brain; Brain Injuries; Brain Ischemia; Energy Metabolism; Female; Glucose; Glycerol; Hu | 2001 |
Brain oedema and intracranial hypertension treatment by GLIAS.
Topics: Adolescent; Adult; Aged; Ascorbic Acid; Brain Edema; Brain Injuries; Brain Neoplasms; Buffers; Cereb | 1992 |
Amelioration of brain damage after focal ischemia in the rat by a novel inhibitor of lipid peroxidation.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Brain Ischemia; Cerebral Arteries; Glycerol; In Vitro T | 1991 |
Magnetic resonance study of brain oedema induced by cold injury--changes in relaxation times before and after the administration of glycerol.
Topics: Animals; Body Water; Brain; Brain Edema; Brain Injuries; Cold Temperature; Dogs; Glycerol; Magnetic | 1990 |
Clinical study of mannitol and glycerol on raised intracranial pressure and on their rebound phenomenon.
Topics: Adult; Aged; Brain Edema; Brain Injuries; Cerebral Hemorrhage; Drug Administration Schedule; Female; | 1990 |
Glycerol dehydrates traumatic and cold-lesioned brain edema as well as normal brain.
Topics: Animals; Body Water; Brain; Brain Edema; Brain Injuries; Cold Temperature; Glycerol | 1990 |
Influence of thermal stress and various agents on the brain edema formation in rats following a cryogenic brain lesion.
Topics: Animals; Body Water; Brain Edema; Brain Injuries; Cold Temperature; Glycerol; Hot Temperature; Ketam | 1989 |
[Use of glycerin in the treatment of increased intracranial pressure in craniocerebral injuries].
Topics: Brain Injuries; Glycerol; Intracranial Pressure | 1972 |
Effect of regional cerebral blood flow of compression by a mass lesion.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Brain Neoplasms; Carbon Dioxide; Cerebral Hemorrhage; C | 1972 |
[Clinical and electroencephalographic studies during treatment with glycerin of chronic forms of increased intracranial pressure].
Topics: Arachnoiditis; Brain Injuries; Cerebral Cortex; Electroencephalography; Epilepsy; Female; Glycerol; | 1972 |
[Studies on oxygen tension, acid-base equilibrium, acid metabolites and electrolytes in blood and cerebrospinal fluid in brain stem contusions and compared to other brain lesions].
Topics: Acid-Base Equilibrium; Animals; Arteries; Bicarbonates; Brain Injuries; Brain Stem; Carbon Dioxide; | 1972 |
Intraventricular pressure after administration of dehydrating agents to severely brain-injured patients: is there a rebound phenomenon?
Topics: Brain Diseases; Brain Edema; Brain Injuries; Glycerol; Humans; Intracranial Pressure; Mannitol; Retr | 1971 |
[Trial of glycerin in cerebral injury in the newborn].
Topics: Asphyxia Neonatorum; Brain Injuries; Glycerol; Humans; Infant, Newborn | 1965 |