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glycerol and Bacterial Meningitides

glycerol has been researched along with Bacterial Meningitides in 23 studies

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Research Excerpts

ExcerptRelevanceReference
"Actuarial recurrence rates were 50% at 12 months and 60% at 24 months."6.43Percutaneous retrogasserian glycerol rhizotomy in the treatment of tic douloureux associated with multiple sclerosis. ( Bisnaire, D; Ferguson, GG; Pickett, GE, 2005)
" An 82-year-old man with trigeminal neuralgia and senile dementia developed signs of meningitis 24 h after retrogasserian glycerol injection."3.68Meningitis due to Gemella haemolysans after neurosurgical treatment of trigeminal neuralgia. ( Aspevall, O; Hillebrant, E; Linderoth, B; Rylander, M, 1991)
"Glycerol and placebo were indistinguishable by colour or taste."2.76Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: a double-blind, randomised controlled trial. ( Ajdukiewicz, KM; Cartwright, KE; French, N; Goodson, P; Lalloo, DG; Molyneux, ME; Mwambene, JB; Scarborough, M; Whitty, CJ; Zijlstra, EE, 2011)
"With bacterial meningitis, the child's presenting status and young age are the most important predictors of hearing impairment."2.75Hearing impairment in childhood bacterial meningitis is little relieved by dexamethasone or glycerol. ( Arbo, A; Bologna, R; Dourado de Andrade, S; Fernández, J; Gonzalez Ayala, S; González Mata, A; Goyo, J; Jauhiainen, T; López, E; Miño, G; Peltola, H; Roine, I; Sarna, S; Zavala, I, 2010)
"Neurological and hearing impairment was assessed at discharge and after 1 month."2.73Role of dexamethasone and oral glycerol in reducing hearing and neurological sequelae in children with bacterial meningitis. ( Bansal, A; Ray, P; Sankar, J; Singhi, P; Singhi, S, 2007)
"Primary end points were death, severe neurological sequelae, or deafness, with the first 2 end points forming a composite end point."2.73Adjuvant glycerol and/or dexamethasone to improve the outcomes of childhood bacterial meningitis: a prospective, randomized, double-blind, placebo-controlled trial. ( Arbo, A; Ayala, SG; Bologna, R; de Andrade, SD; Fernández, J; Goyo, J; López, E; Mata, AG; Miño, G; Peltola, H; Roine, I; Sarna, S; Zavala, I, 2007)
"Glycerol was the only osmotic therapy evaluated, and data from trials to date have not demonstrated an effect on death."2.58Osmotic therapies added to antibiotics for acute bacterial meningitis. ( Ajdukiewicz, KM; Bergman, H; Garner, P; Heyderman, RS; Wall, EC, 2018)
"Adequate and prompt treatment of bacterial meningitis is critical to outcome."2.50Bacterial meningitis. ( Brouwer, MC; Heckenberg, SG; van de Beek, D, 2014)
"Neither of the adjuvants prevented hearing impairment, regardless of agent or timing of antibiotic."2.45Improving the outcomes in children with bacterial meningitis. ( Peltola, H; Roine, I, 2009)
"Actuarial recurrence rates were 50% at 12 months and 60% at 24 months."2.43Percutaneous retrogasserian glycerol rhizotomy in the treatment of tic douloureux associated with multiple sclerosis. ( Bisnaire, D; Ferguson, GG; Pickett, GE, 2005)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (17.39)18.2507
2000's8 (34.78)29.6817
2010's11 (47.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wall, EC2
Ajdukiewicz, KM3
Bergman, H1
Heyderman, RS2
Garner, P2
Forssten, MP1
Thelin, EP1
Nelson, DW1
Bellander, BM1
Musa, SH1
Basri, M1
Masoumi, HR1
Karjiban, RA1
Malek, EA1
Basri, H1
Shamsuddin, AF1
Molyneux, EM1
Kawaza, K1
Phiri, A1
Chimalizeni, Y1
Mankhambo, L1
Schwalbe, E1
Kataja, M1
Pensulo, P1
Chilton, L1
Peltola, H9
Heckenberg, SG1
Brouwer, MC2
van de Beek, D2
Leib, SL1
Singhi, S4
Singhi, P2
Järvinen, A1
Roine, I5
Fernández, J2
González Mata, A1
Zavala, I2
Gonzalez Ayala, S1
Arbo, A2
Bologna, R2
Goyo, J2
López, E2
Miño, G2
Dourado de Andrade, S1
Sarna, S2
Jauhiainen, T2
Cartwright, KE1
Scarborough, M1
Mwambene, JB1
Goodson, P1
Molyneux, ME1
Zijlstra, EE1
French, N1
Whitty, CJ1
Lalloo, DG1
Pickett, GE1
Bisnaire, D1
Ferguson, GG1
Sankar, J1
Bansal, A1
Ray, P1
Ayala, SG1
Mata, AG1
de Andrade, SD1
Sáez-Llorens, X1
McCracken, GH1
Kilpi, T1
Kallio, MJ1
James, EA1
Kibbler, CC1
Gillespie, SH1
Thurston, JH1
Hauhart, RE1
Dirgo, JA1
Aspevall, O1
Hillebrant, E1
Linderoth, B1
Rylander, M1

Reviews

6 reviews available for glycerol and Bacterial Meningitides

ArticleYear
Osmotic therapies added to antibiotics for acute bacterial meningitis.
    The Cochrane database of systematic reviews, 2018, 02-06, Volume: 2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Child; Combined Modality Therapy;

2018
Osmotic therapies added to antibiotics for acute bacterial meningitis.
    The Cochrane database of systematic reviews, 2013, Mar-28, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Child; Combined Modality Therapy;

2013
Bacterial meningitis.
    Handbook of clinical neurology, 2014, Volume: 121

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Dexamethasone; Glycerol; Humans; Meningitis, Bacter

2014
Performance of adjunctive therapy in bacterial meningitis depends on circumstances.
    The Pediatric infectious disease journal, 2013, Volume: 32, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Daptomycin; Developing Countries; Dexamethasone; Gl

2013
Improving the outcomes in children with bacterial meningitis.
    Current opinion in infectious diseases, 2009, Volume: 22, Issue:3

    Topics: Anti-Bacterial Agents; Child; Child, Preschool; Clinical Trials as Topic; Dexamethasone; Glycerol; H

2009
Percutaneous retrogasserian glycerol rhizotomy in the treatment of tic douloureux associated with multiple sclerosis.
    Neurosurgery, 2005, Volume: 56, Issue:3

    Topics: Adult; Analgesics; Carbamazepine; Combined Modality Therapy; Female; Follow-Up Studies; Glycerol; Hu

2005

Trials

7 trials available for glycerol and Bacterial Meningitides

ArticleYear
Glycerol and acetaminophen as adjuvant therapy did not affect the outcome of bacterial meningitis in Malawian children.
    The Pediatric infectious disease journal, 2014, Volume: 33, Issue:2

    Topics: Acetaminophen; Anti-Bacterial Agents; Ceftriaxone; Double-Blind Method; Drug Therapy, Combination; G

2014
Increase in serum osmolality is possible mechanism for the beneficial effects of glycerol in childhood bacterial meningitis.
    The Pediatric infectious disease journal, 2008, Volume: 27, Issue:10

    Topics: Ceftriaxone; Cerebrovascular Circulation; Child; Child, Preschool; Dexamethasone; Double-Blind Metho

2008
Hearing impairment in childhood bacterial meningitis is little relieved by dexamethasone or glycerol.
    Pediatrics, 2010, Volume: 125, Issue:1

    Topics: Administration, Oral; Adolescent; Audiometry; Ceftriaxone; Child; Child, Preschool; Confidence Inter

2010
Glycerol adjuvant therapy in adults with bacterial meningitis in a high HIV seroprevalence setting in Malawi: a double-blind, randomised controlled trial.
    The Lancet. Infectious diseases, 2011, Volume: 11, Issue:4

    Topics: Adjuvants, Pharmaceutic; Adult; Anti-Bacterial Agents; Double-Blind Method; Drug Therapy, Combinatio

2011
Role of dexamethasone and oral glycerol in reducing hearing and neurological sequelae in children with bacterial meningitis.
    Indian pediatrics, 2007, Volume: 44, Issue:9

    Topics: Acute Disease; Administration, Oral; Child; Child, Preschool; Dexamethasone; Dose-Response Relations

2007
Adjuvant glycerol and/or dexamethasone to improve the outcomes of childhood bacterial meningitis: a prospective, randomized, double-blind, placebo-controlled trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Nov-15, Volume: 45, Issue:10

    Topics: Adolescent; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ceftriaxone; Chemotherapy, Adjuvant; Ch

2007
Oral glycerol and intravenous dexamethasone in preventing neurologic and audiologic sequelae of childhood bacterial meningitis. The Finnish Study Group.
    The Pediatric infectious disease journal, 1995, Volume: 14, Issue:4

    Topics: Administration, Oral; Adolescent; Ceftriaxone; Child; Child, Preschool; Confidence Intervals; Dexame

1995

Other Studies

10 other studies available for glycerol and Bacterial Meningitides

ArticleYear
The Role of Glycerol-Containing Drugs in Cerebral Microdialysis: A Retrospective Study on the Effects of Intravenously Administered Glycerol.
    Neurocritical care, 2019, Volume: 30, Issue:3

    Topics: Administration, Intravenous; Adult; Brain Injuries, Traumatic; Cerebrum; Critical Care; Extracellula

2019
Formulation optimization of palm kernel oil esters nanoemulsion-loaded with chloramphenicol suitable for meningitis treatment.
    Colloids and surfaces. B, Biointerfaces, 2013, Dec-01, Volume: 112

    Topics: Anti-Bacterial Agents; Blood-Brain Barrier; Chemistry, Pharmaceutical; Chloramphenicol; Drug Carrier

2013
Glycerol and dexamethasone in bacterial meningitis in low-income countries: response to the editorial commentary by Sáez-Llorens and McCracken Jr.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Sep-01, Volume: 47, Issue:5

    Topics: Child; Developing Countries; Dexamethasone; Glycerol; Humans; Immunologic Factors; Meningitis, Bacte

2008
Glycerol in bacterial meningitis: one strike and out?
    The Lancet. Infectious diseases, 2011, Volume: 11, Issue:4

    Topics: Adjuvants, Pharmaceutic; Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Glycerol;

2011
Glycerol in meningitis should not be condemned so hastily.
    The Lancet. Infectious diseases, 2011, Volume: 11, Issue:12

    Topics: Adjuvants, Pharmaceutic; Anti-Bacterial Agents; Female; Glycerol; HIV Infections; HIV Seroprevalence

2011
Glycerol and bacterial meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Nov-15, Volume: 45, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Chemotherapy, Adjuvant; Child; Child, Preschool; De

2007
Glycerol and bacterial meningitis: a response to the editorial commentary by Sáez-Llorens and McCracken.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Apr-01, Volume: 46, Issue:7

    Topics: Child; Child, Preschool; Dexamethasone; Glycerol; Humans; Meningitis, Bacterial

2008
Meningitis due to oral streptococci following percutaneous glycerol rhizotomy of the trigeminal ganglion.
    The Journal of infection, 1995, Volume: 31, Issue:1

    Topics: Glycerol; Humans; Male; Meningitis, Bacterial; Middle Aged; Mouth; Rhizotomy; Streptococcal Infectio

1995
Glycerol treatment in bacterial meningitis.
    The Pediatric infectious disease journal, 1996, Volume: 15, Issue:1

    Topics: Animals; Glycerol; Humans; Kidney Cortex; Liver; Meningitis, Bacterial; Mice; Rats

1996
Meningitis due to Gemella haemolysans after neurosurgical treatment of trigeminal neuralgia.
    Scandinavian journal of infectious diseases, 1991, Volume: 23, Issue:4

    Topics: Aged; Aged, 80 and over; Glycerol; Gram-Positive Cocci; Humans; Male; Meningitis, Bacterial; Trigemi

1991