glyceraldehyde has been researched along with Pancreatic Neoplasms in 13 studies
Glyceraldehyde: An aldotriose containing the propionaldehyde structure with hydroxy groups at the 2- and 3-positions. It is involved in the formation of ADVANCED GLYCOSYLATION END PRODUCTS.
glyceraldehyde : An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing.
aldose : Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To elucidate the regulatory pathway through which pancreastatin inhibits insulin secretion, RINm5F insulinoma cells were challenged with physiological and pharmacological probes known to stimulate insulin release through different mechanisms." | 3.69 | Pancreastatin inhibits insulin secretion in RINm5F cells through obstruction of G-protein mediated, calcium-directed exocytosis. ( Hertelendy, ZI; Knittel, JJ; Patel, DG, 1996) |
| " Amylin significantly reduced insulin secretion in rat insulinoma cell lines (Rin m5F cells) that were stimulated by either isoproterenol and forskolin, but it did not affect insulin secretion stimulated by isobutyl-methylxanthine (IBMX) or dibutyryl cyclic-adenosine monophosphate (db-cAMP)." | 3.68 | The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes. ( Abe, S; Ishizuka, J; Murakami, M; Satoh, Y; Shintani, S; Suzuki, K; Suzuki, S; Thompson, JC; Toyota, T, 1992) |
| "We studied the release of insulin, glucagon, and somatostatin in response to glucose, glyceraldehyde (GA), and alpha-ketoisocaproate (KIC) from rat kidneys containing transplanted insulinomas." | 3.67 | Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney. ( Ferguson, DC; Hoenig, M; Matschinsky, FM, 1984) |
| "Our functional studies showed that pancreatic cancer cells (PANC-1 and MIA PaCa-2) were more resistant to glyceraldehyde treatment compared to normal pancreatic ductal epithelial cells (HPDE), while cytotoxicity effects were observed in all cell types." | 1.62 | Proteomic Investigation of Glyceraldehyde-Derived Intracellular AGEs and Their Potential Influence on Pancreatic Ductal Cells. ( Chen, R; Ma, C; Pan, S; Senavirathna, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Senavirathna, L | 1 |
| Ma, C | 1 |
| Chen, R | 1 |
| Pan, S | 1 |
| Wollheim, CB | 3 |
| Ullrich, S | 1 |
| Pozzan, T | 1 |
| Praz, GA | 1 |
| Halban, PA | 1 |
| Blondel, B | 2 |
| Strauss, AJ | 1 |
| Renold, AE | 1 |
| Hoenig, M | 2 |
| Ferguson, DC | 1 |
| Matschinsky, FM | 1 |
| Norling, LL | 1 |
| Colca, JR | 1 |
| Kelly, PT | 1 |
| McDaniel, ML | 1 |
| Landt, M | 1 |
| Hertelendy, ZI | 1 |
| Patel, DG | 1 |
| Knittel, JJ | 1 |
| Suzuki, S | 1 |
| Murakami, M | 2 |
| Abe, S | 1 |
| Satoh, Y | 1 |
| Shintani, S | 1 |
| Ishizuka, J | 2 |
| Suzuki, K | 1 |
| Thompson, JC | 2 |
| Toyota, T | 1 |
| Sumi, S | 1 |
| Nickols, GA | 1 |
| Cooper, CW | 1 |
| Townsend, CM | 1 |
| Trautmann, ME | 1 |
| Gjinovci, A | 1 |
| Petersen, OH | 1 |
| Findlay, I | 1 |
| Dunne, MJ | 1 |
| Sullivan, SJ | 2 |
| Schonbrunn, A | 2 |
| Sharp, GW | 1 |
13 other studies available for glyceraldehyde and Pancreatic Neoplasms
| Article | Year |
|---|---|
Proteomic Investigation of Glyceraldehyde-Derived Intracellular AGEs and Their Potential Influence on Pancreatic Ductal Cells.
Topics: Apoptosis; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Survival; Glycation End Products, A | 2021 |
Glyceraldehyde, but not cyclic AMP-stimulated insulin release is preceded by a rise in cytosolic free Ca2+.
Topics: Aminoquinolines; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Fluorescent D | 1984 |
Regulation of immunoreactive-insulin release from a rat cell line (RINm5F).
Topics: Adenoma, Islet Cell; Amino Acids; Animals; Cations; Cell Line; Epinephrine; Glucagon; Glucose; Glyce | 1983 |
Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney.
Topics: Adenoma, Islet Cell; Animals; Cytochalasin B; Diazoxide; Glucagon; Glucose; Glyceraldehyde; Humans; | 1984 |
Activation of calcium and calmodulin dependent protein kinase II during stimulation of insulin secretion.
Topics: Animals; Autoradiography; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dep | 1994 |
Pancreastatin inhibits insulin secretion in RINm5F cells through obstruction of G-protein mediated, calcium-directed exocytosis.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Calcium; Carbachol; Chromogranin A; Exocytosis; Glyceral | 1996 |
The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes.
Topics: Acetates; Amyloid; Animals; Arginine; Blood Glucose; Cell Line; Cells, Cultured; Colforsin; Cyclic A | 1992 |
Role of extracellular magnesium in insulin secretion from rat insulinoma cells.
Topics: Animals; Calcium; Cell Line; Colforsin; Glyburide; Glyceraldehyde; Insulin; Insulin Secretion; Insul | 1992 |
Inverse relationship between glucose metabolism and glucose-induced insulin secretion in rat insulinoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Dose-Response Relationship, Drug; Glucose; Glyceraldehy | 1990 |
Inhibition of K-channels in insulin secreting cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; | 1986 |
Characterization of somatostatin receptors which mediate inhibition of insulin secretion in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Binding, Competitive; Cell Line; Glyceraldehyde; Insulin; Insulin Secr | 1987 |
Distribution of somatostatin receptors in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Cell Fractionation; Cell Membrane; Colforsin; Cytoplasmic Granules; Cy | 1988 |
Glucose induces insulin release and a rise in cytosolic calcium concentration in a transplantable rat insulinoma.
Topics: Adenoma, Islet Cell; Aminoquinolines; Animals; Calcium; Carbachol; Cytosol; Dose-Response Relationsh | 1986 |