glyceraldehyde has been researched along with Insulinoma in 15 studies
Glyceraldehyde: An aldotriose containing the propionaldehyde structure with hydroxy groups at the 2- and 3-positions. It is involved in the formation of ADVANCED GLYCOSYLATION END PRODUCTS.
glyceraldehyde : An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing.
aldose : Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.
Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The addition of the triose D-glyceraldehyde (5-20 mM) to HIT-T15 hamster insulinoma cells caused a rapid, marked depolarisation of the plasma membrane accompanied by a pronounced intracellular acidification, an increase in the cytosolic free calcium concentration [Ca2+]i and enhanced secretion of insulin." | 7.68 | Stimulation of HIT-T15 insulinoma cells by glyceraldehyde does not require its metabolism. ( Best, L; Elliott, AC; Trebilcock, R; Yates, AP, 1993) |
| "D-Glyceraldehyde was transported into HIT-T15 cells at a linear rate for approx." | 5.29 | A possible role for glyceraldehyde transport in the stimulation of HIT-T15 insulinoma cells. ( Best, L; Davies, J; Elliott, AC; Tomlinson, S, 1994) |
| "To elucidate the regulatory pathway through which pancreastatin inhibits insulin secretion, RINm5F insulinoma cells were challenged with physiological and pharmacological probes known to stimulate insulin release through different mechanisms." | 3.69 | Pancreastatin inhibits insulin secretion in RINm5F cells through obstruction of G-protein mediated, calcium-directed exocytosis. ( Hertelendy, ZI; Knittel, JJ; Patel, DG, 1996) |
| " In this study, the effects of galanin and the galanin receptor antagonist, galantide, on the cytoplasmic free Ca2+ [Ca2+]i, were investigated in FURA 2-AM-loaded cells of the rat insulinoma cell line, RIN m5F, in cell suspensions in a cuvette." | 3.68 | Dual action of the neuropeptide galanin on the cytoplasmic free calcium concentration in RIN m5F cells. ( Ahrén, B; Fridolf, T, 1993) |
| "The addition of the triose D-glyceraldehyde (5-20 mM) to HIT-T15 hamster insulinoma cells caused a rapid, marked depolarisation of the plasma membrane accompanied by a pronounced intracellular acidification, an increase in the cytosolic free calcium concentration [Ca2+]i and enhanced secretion of insulin." | 3.68 | Stimulation of HIT-T15 insulinoma cells by glyceraldehyde does not require its metabolism. ( Best, L; Elliott, AC; Trebilcock, R; Yates, AP, 1993) |
| " Amylin significantly reduced insulin secretion in rat insulinoma cell lines (Rin m5F cells) that were stimulated by either isoproterenol and forskolin, but it did not affect insulin secretion stimulated by isobutyl-methylxanthine (IBMX) or dibutyryl cyclic-adenosine monophosphate (db-cAMP)." | 3.68 | The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes. ( Abe, S; Ishizuka, J; Murakami, M; Satoh, Y; Shintani, S; Suzuki, K; Suzuki, S; Thompson, JC; Toyota, T, 1992) |
| "We studied the release of insulin, glucagon, and somatostatin in response to glucose, glyceraldehyde (GA), and alpha-ketoisocaproate (KIC) from rat kidneys containing transplanted insulinomas." | 3.67 | Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney. ( Ferguson, DC; Hoenig, M; Matschinsky, FM, 1984) |
| "D-Glyceraldehyde was transported into HIT-T15 cells at a linear rate for approx." | 1.29 | A possible role for glyceraldehyde transport in the stimulation of HIT-T15 insulinoma cells. ( Best, L; Davies, J; Elliott, AC; Tomlinson, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 9 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wollheim, CB | 2 |
| Ullrich, S | 1 |
| Pozzan, T | 1 |
| Hoenig, M | 3 |
| Ferguson, DC | 2 |
| Matschinsky, FM | 1 |
| Fridolf, T | 1 |
| Ahrén, B | 1 |
| Norling, LL | 1 |
| Colca, JR | 1 |
| Kelly, PT | 1 |
| McDaniel, ML | 1 |
| Landt, M | 1 |
| Davies, J | 1 |
| Tomlinson, S | 1 |
| Elliott, AC | 2 |
| Best, L | 2 |
| Trebilcock, R | 1 |
| Yates, AP | 1 |
| Hertelendy, ZI | 1 |
| Patel, DG | 1 |
| Knittel, JJ | 1 |
| Culberson, LH | 1 |
| Clement, JM | 1 |
| Suzuki, S | 1 |
| Murakami, M | 2 |
| Abe, S | 1 |
| Satoh, Y | 1 |
| Shintani, S | 1 |
| Ishizuka, J | 2 |
| Suzuki, K | 1 |
| Thompson, JC | 2 |
| Toyota, T | 1 |
| Sumi, S | 1 |
| Nickols, GA | 1 |
| Cooper, CW | 1 |
| Townsend, CM | 1 |
| Trautmann, ME | 1 |
| Blondel, B | 1 |
| Gjinovci, A | 1 |
| Petersen, OH | 1 |
| Findlay, I | 1 |
| Dunne, MJ | 1 |
| Sullivan, SJ | 2 |
| Schonbrunn, A | 2 |
| Sharp, GW | 1 |
15 other studies available for glyceraldehyde and Insulinoma
| Article | Year |
|---|---|
Glyceraldehyde, but not cyclic AMP-stimulated insulin release is preceded by a rise in cytosolic free Ca2+.
Topics: Aminoquinolines; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Fluorescent D | 1984 |
Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney.
Topics: Adenoma, Islet Cell; Animals; Cytochalasin B; Diazoxide; Glucagon; Glucose; Glyceraldehyde; Humans; | 1984 |
Dual action of the neuropeptide galanin on the cytoplasmic free calcium concentration in RIN m5F cells.
Topics: Animals; Calcium; Carbachol; Cytoplasm; Galanin; Glyceraldehyde; In Vitro Techniques; Insulin; Insul | 1993 |
Activation of calcium and calmodulin dependent protein kinase II during stimulation of insulin secretion.
Topics: Animals; Autoradiography; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dep | 1994 |
A possible role for glyceraldehyde transport in the stimulation of HIT-T15 insulinoma cells.
Topics: Coumaric Acids; Ethylmaleimide; Glyceraldehyde; Humans; Insulinoma; Membrane Potentials; Sodium; Tum | 1994 |
Stimulation of HIT-T15 insulinoma cells by glyceraldehyde does not require its metabolism.
Topics: Animals; Cricetinae; Glyceraldehyde; Hydrogen-Ion Concentration; Insulin; Insulinoma; Membrane Poten | 1993 |
Pancreastatin inhibits insulin secretion in RINm5F cells through obstruction of G-protein mediated, calcium-directed exocytosis.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Calcium; Carbachol; Chromogranin A; Exocytosis; Glyceral | 1996 |
Na+/Ca2+ exchange in plasma membrane vesicles from a glucose-responsive insulinoma.
Topics: Animals; Calcium; Cell Membrane; Glyceraldehyde; Insulinoma; Ion Pumps; Male; Monensin; Onium Compou | 1992 |
The effects of amylin on insulin secretion from Rin m5F cells and glycogen synthesis and lipogenesis in rat primary cultured hepatocytes.
Topics: Acetates; Amyloid; Animals; Arginine; Blood Glucose; Cell Line; Cells, Cultured; Colforsin; Cyclic A | 1992 |
Role of extracellular magnesium in insulin secretion from rat insulinoma cells.
Topics: Animals; Calcium; Cell Line; Colforsin; Glyburide; Glyceraldehyde; Insulin; Insulin Secretion; Insul | 1992 |
Inverse relationship between glucose metabolism and glucose-induced insulin secretion in rat insulinoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Dose-Response Relationship, Drug; Glucose; Glyceraldehy | 1990 |
Inhibition of K-channels in insulin secreting cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Glyceraldehyde; Insulin; Insulin Secretion; Insulinoma; | 1986 |
Characterization of somatostatin receptors which mediate inhibition of insulin secretion in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Binding, Competitive; Cell Line; Glyceraldehyde; Insulin; Insulin Secr | 1987 |
Distribution of somatostatin receptors in RINm5F insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Cell Fractionation; Cell Membrane; Colforsin; Cytoplasmic Granules; Cy | 1988 |
Glucose induces insulin release and a rise in cytosolic calcium concentration in a transplantable rat insulinoma.
Topics: Adenoma, Islet Cell; Aminoquinolines; Animals; Calcium; Carbachol; Cytosol; Dose-Response Relationsh | 1986 |